Urological manifestations articles from across Nature Portfolio

A study using a large electronic health record database found that patients with colour vision deficiency had lower survival rates for bladder cancer, possibly because they may not be able to detect gross haematuria in time.

Management of erectile dysfunction has previously focused on symptom management, but attention is now being directed towards interventions that facilitate and retain natural erectile ability, treating the underlying cause of the disorder. In this Perspective article, the authors discuss the potential of electrical neurostimulation of the penis, which is in early stages of development as a restorative therapy, targeting the penile-nerve supply that is impaired by disease states, injury or ageing.

Persistent Müllerian duct syndrome (PMDS) is a rare difference in sex development, characterized by the presence of Müllerian duct derivatives in 46,XY individuals with male-typical development. Untreated PMDS is associated with risks of infertility and malignancy. In this Review, the authors provide an comprehensive primer on the epidemiology, pathophysiology and management of the condition, considering the need for a high index of clinical suspicion and timely intervention, raised awareness of PMDS among clinicians and multidisciplinary care to optimize outcomes for patients.

This study investigates the role of SMAD2 genetic variants associated with congenital heart disease on renal development using a CRISPR-engineered human induced pluripotent stem cell model on a microphysiological system.

A study using a large electronic health record database found that patients with colour vision deficiency had lower survival rates for bladder cancer, possibly because they may not be able to detect gross haematuria in time.

The high prevalence of urological conditions means that it should not come as a surprise that we, as urologists, have a high chance of one day needing the assistance of a urological colleague. As a urological patient, the lessons are humbling and provide an incredible opportunity to do better for our own patients.

Large language models have been rapidly adopted in general and clinically; they could also be incorporated into medical education. Results of a recent study suggest that a combination of traditional learning methods and large language model use could improve learning outcomes for medical students.

Pronouns are small but mighty words. However, the conscious use of gender-neutral pronouns has recently led to heated discussions and has been implicated in legislation and cases of employment termination. Importantly, failing to respect a person’s pronouns can lead to real harm in physical and psychological health.