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Showing 1–50 of 51 results

Advanced filters: Author: Chunyan Fu Clear advanced filters

A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis

Zhang, Ma et al. report that ROS-activated O-GlcNAc transferase promotes FOXK2 O-GlcNAcylation and nuclear translocation to upregulate SLC7A11 expression, thereby modulating ferroptosis sensitivity, tumour development and chemoradiotherapy efficacy.

Hemeng Zhang
Jialin Ma
Huadong Pei
Research18 Jul 2025
Nature Cell Biology

Volume: 27, P: 1288-1300
Publisher Correction: Selective electrified polyethylene upcycling by pore-modulated pyrolysis

Ji Yang
Qi Dong
Liangbing Hu
Amendments and Corrections14 Aug 2025
Nature Chemical Engineering

P: 1
Selective electrified polyethylene upcycling by pore-modulated pyrolysis

A pore-modulated pyrolysis reactor that enables catalyst-free and energy-efficient upcycling of plastic waste is demonstrated. The graded-pore structure imposes molecular-weight-dependent transport barriers, establishing a gating effect that enhances product selectivity and yields aviation fuel precursor (C₈–C₁₈) with high efficiency.

Ji Yang
Qi Dong
Liangbing Hu
Research22 Jul 2025
Nature Chemical Engineering

Volume: 2, P: 424-435
Tislelizumab (anti-PD-1) plus chemotherapy as neoadjuvant therapy for patients with stage IB3/IIA2 cervical cancer (NATIC): a prospective, single-arm, phase II study

Jindong Sheng
Haitao Luo
Wenxin Liu
ResearchOpen Access04 Jul 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-10
The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy

Jian Chen
Risi Na
Zhihai Peng
ResearchOpen Access14 May 2021
Oncogene

Volume: 40, P: 3974-3988
USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer

Yi Xiao
Xiaoyu Jiang
Pengju Zhang
ResearchOpen Access03 Mar 2023
Oncogenesis

Volume: 12, P: 1-14
Fast segmentation and multiplexing imaging of organelles in live cells

The authors demonstrate an AI-enhanced imaging method combining lipid-specific dyes and super-resolution microscopy enables simultaneous tracking of up to 15 organelles in living cells, revealing dynamic interactions across diverse biological systems.

Karl Zhanghao
Meiqi Li
Dayong Jin
ResearchOpen Access21 Mar 2025
Nature Communications

Volume: 16, P: 1-14
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

A broad-range human antibody with neutralizing activity against various coronaviruses, including SARS-CoV-2, targets a unique epitope within the highly conserved S2’ site and the fusion peptide of the spike protein that is exposed during interaction with the host cell. The pan-coronavirus antibody protects mice against infection with SARS-CoV-2 and HCoV-OC43 following prophylactic and therapeutic treatment.

Xiaoyu Sun
Chunyan Yi
Bing Sun
Research30 Jun 2022
Nature Microbiology

Volume: 7, P: 1063-1074
Self-propelled assembly of nanoparticles with self-catalytic regulation for tumour-specific imaging and therapy

In vivo manipulation of the dynamics of nanoparticles’ is essential for disease-specific imaging and therapy, but tends to involve complex design processes. Here, the authors report a strategy for manipulating the assembly of nanoparticles in vivo through a self-catalysis-instructed dimerization of tyrosine, offering convenient fabrication, high reaction specificity and biocompatibility.

Mengmeng Xia
Qiyue Wang
Daishun Ling
ResearchOpen Access11 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Towards social sustainability in urban communities: exploring how community parks influence residents’ social interaction during the COVID-19 pandemic

Chunyan Yang
Song Shi
Duanfang Lu
ResearchOpen Access08 Nov 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-17
Uncovering the transcriptional regulatory network involved in boosting wheat regeneration and transformation

Wheat functional genomics is limited by low transformation efficiency. This study uncovered the transcriptional regulatory network responsible for wheat regeneration and identified two DOF transcription factors that can enhance regeneration in wheat.

Xuemei Liu
Xiao Min Bie
Jun Xiao
Research04 May 2023
Nature Plants

Volume: 9, P: 908-925
Erratum: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

Min Deng
Ling Wei
Xuejun Zhang
Amendments and Corrections29 May 2013
Nature Genetics

Volume: 45, P: 714
Transforming CO₂ into advanced 3D printed carbon nanocomposites

This work develops a method to sequester carbon emissions into valuable 3D printed materials. By combining a reactor cascade with advanced additive manufacturing, this system offers the ability for carbon utilization at scale, a crucial step for addressing climate change.

Bradie S. Crandall
Matthew Naughton
Feng Jiao
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-9
Percutaneous intervertebral bridging cementoplasty for adjacent multilevel osteoporotic thoracolumbar fractures with vertebral endplate-disc complex injury: technical note

Song Wang
Chunyan Duan
Qing Wang
ResearchOpen Access01 Sept 2020
Scientific Reports

Volume: 10, P: 1-8
Proteomic profiling of HIV-1 infection of human CD4⁺ T cells identifies PSGL-1 as an HIV restriction factor

Proteomic analysis of human immunodeficiency virus (HIV-1)-infected human primary T cells identifies P-selectin glycoprotein ligand 1 as an HIV-1 restriction factor, which can inhibit HIV-1 reverse transcription and block viral infectivity through incorporation in progeny virions antagonized by HIV-1 viral protein U.

Ying Liu
Yajing Fu
Xu Tan
Research04 Mar 2019
Nature Microbiology

Volume: 4, P: 813-825
AtPRMT3-RPS2B promotes ribosome biogenesis and coordinates growth and cold adaptation trade-off

Ribosome biogenesis and translation are essential processes for cellular activity. Here, the authors illustrated the role of AtPRMT3-RPS2B in maintaining ribosome assembly and coordinating growth-stress trade-off.

Zhen Wang
Xiaofan Zhang
Xiaofeng Cao
ResearchOpen Access08 Oct 2024
Nature Communications

Volume: 15, P: 1-14
Inequities in prenatal neonatology consultation in high-mortality neonatal populations

Samantha L. Simpson
Kylie Mena
Emily R. Miller
ResearchOpen Access20 Aug 2025
Journal of Perinatology

Volume: 45, P: 1198-1206
BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability

The genomic instability phenotype characteristic of BRCA2-deficient cells is not fully mechanistically understood. Here the authors show BRCA2 inactivation destabilizes RPA-coated single-stranded DNA and leads to toxic non homologous end-joining events.

Jinhua Han
Chunyan Ruan
Jun Huang
ResearchOpen Access13 Nov 2017
Nature Communications

Volume: 8, P: 1-16
Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii

Tree peony (Paeonia ostii) has the largest chromosome of any sequenced plants to date. Here, the authors assemble its genome and reveal the association of a list of candidate genes with fatty acid biosynthesis and the possible contribution of transposon and histone expansion to maintain the giga-chromosomes.

Junhui Yuan
Sanjie Jiang
Yonghong Hu
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-16
Global systematic review with meta-analysis shows that warming effects on terrestrial plant biomass allocation are influenced by precipitation and mycorrhizal association

Biomass allocation in plants is fundamental for understanding and predicting terrestrial carbon storage. Here, the authors conduct a meta-analysis showing that warming effect on plant root:shoot is influenced by precipitation and the type of mycorrhizal fungi associated.

Lingyan Zhou
Xuhui Zhou
Madhav P. Thakur
ResearchOpen Access20 Aug 2022
Nature Communications

Volume: 13, P: 1-10
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

A small-molecule aldolase inhibitor, aldolazin is reported and shown to selectively activate the lysosomal pool of AMPK, which has glucose-lowering effects in rodents.

Chen-Song Zhang
Mengqi Li
Sheng-Cai Lin
ResearchOpen Access10 Oct 2022
Nature Metabolism

Volume: 4, P: 1369-1401
Sequence and analysis of rice chromosome 4

Qi Feng
Yujun Zhang
Bin Han
Research21 Nov 2002
Nature

Volume: 420, P: 316-320
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis

Min Deng, Kai Wang and colleagues report genome-wide association analyses of amyotrophic lateral sclerosis in the Han Chinese population. They identify two new risk loci at 1q32 and 22p11.

Min Deng
Ling Wei
Xuejun Zhang
Research28 Apr 2013
Nature Genetics

Volume: 45, P: 697-700
Deep convolutional neural network-based classification of cancer cells on cytological pleural effusion images

Xiaofeng Xie
Chi-Cheng Fu
Chunyan Wu
ResearchOpen Access10 Jan 2022
Modern Pathology

Volume: 35, P: 609-614
FBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth

Aberrant EGFR activation is commonly found in non-small cell lung cancer (NSCLC). Here the authors show that E3 ubiquitin ligase FBXL2 targets EGFR and EGFR tyrosine kinase inhibitor (TKI)-resistant mutants for proteasome-mediated degradation to inhibit EGFR-driven NSCLC growth and TKI resistance.

Mengmeng Niu
Jing Xu
Zhi-Xiong Jim Xiao
ResearchOpen Access11 Oct 2021
Nature Communications

Volume: 12, P: 1-15
The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

In cancer the side effects of therapeutic agents can provoke senescence-associated secretory phenotype (SASP), which can drive cancer resistance. During the DNA damage response, transcription factor Zscan4 expression is elevated by an ATM-TRAF6-TAK1 axis leading to long term SASP in human stromal cells.

Boyi Zhang
Da Fu
Yu Sun
ResearchOpen Access30 Apr 2018
Nature Communications

Volume: 9, P: 1-19
Characteristics of patients with autoimmune haemolytic anaemia secondary to lymphoproliferative disorder: A single-centre retrospective analysis

Limin Xing
Manjun Zhao
Zonghong Shao
ResearchOpen Access23 Dec 2019
Scientific Reports

Volume: 9, P: 1-7
Intraoperatively measured tumor size and frozen section results should be considered jointly to predict the final pathology for lung adenocarcinoma

Erjia Zhu
Huikang Xie
Chang Chen
Research11 May 2018
Modern Pathology

Volume: 31, P: 1391-1399
Genetic variations in the fusion protein of respiratory syncytial virus isolated from children hospitalized with community-acquired pneumonia in China

Xiangpeng Chen
Baoping Xu
Zhengde Xie
ResearchOpen Access14 Mar 2018
Scientific Reports

Volume: 8, P: 1-6
A SPR biosensor based on signal amplification using antibody-QD conjugates for quantitative determination of multiple tumor markers

Huan Wang
Xiaomei Wang
Chunyan Yao
ResearchOpen Access12 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans

Polymorphic duplicate genes are important early stages of duplicate gene evolution. Here, the authors characterize polymorphic gene duplicates with respect to dosage, exon–intron structures and allele frequencies for Drosophila and humans.

Dan Zhang
Liang Leng
Yong E. Zhang
Research30 Dec 2021
Nature Ecology & Evolution

Volume: 6, P: 273-287
Impaired 2′,3′-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice

Bin Yan
Chunyan Liu
Xiaofeng Cao
Research09 Sept 2024
Cell Research

Volume: 34, P: 763-775
First mitochondrial genome for the red crab (Charybdis feriata) with implication of phylogenomics and population genetics

Hongyu Ma
Chunyan Ma
Lianjun Xia
ResearchOpen Access30 Jul 2015
Scientific Reports

Volume: 5, P: 1-14
N-methylpurine DNA glycosylase inhibits p53-mediated cell cycle arrest and coordinates with p53 to determine sensitivity to alkylating agents

Shanshan Song
Guichun Xing
Lingqiang Zhang
Research17 Jul 2012
Cell Research

Volume: 22, P: 1285-1303
Multiomics identify the gene expression signature of the spinal cord during aging process

Multiomics sheds light on the gene expression signature of the spinal cord during the ageing process-resistance to ferroptosis via the upregulation of Fth1.

Lintao Xu
Jingyu Wang
Ying-ying Chen
ResearchOpen Access07 Feb 2025
Communications Biology

Volume: 8, P: 1-12
WEE1 kinase polymorphism as a predictive biomarker for efficacy of platinum-gemcitabine doublet chemotherapy in advanced non-small cell lung cancer patients

Di Liu
Chunyan Wu
Bo Su
ResearchOpen Access09 Jun 2015
Scientific Reports

Volume: 5, P: 1-14
Histone chaperone ASF1A accelerates chronic myeloid leukemia blast crisis by activating Notch signaling

Xiaolin Yin
Minran Zhou
Chunyan Chen
ResearchOpen Access03 Oct 2022
Cell Death & Disease

Volume: 13, P: 1-9
Oncoprotein Tudor-SN is a key determinant providing survival advantage under DNA damaging stress

Xiao Fu
Chunyan Zhang
Jie Yang
Research19 Feb 2018
Cell Death & Differentiation

Volume: 25, P: 1625-1637
Metal-free imidazolium salts inhibit the growth of hepatocellular carcinoma in a mouse model

Began Gopalan
Zhiyuan Ke
Lang Zhuo
Research21 Feb 2011
Laboratory Investigation

Volume: 91, P: 744-751
Nonlinear radiative Maxwell nanofluid flow in a Darcy–Forchheimer permeable media over a stretching cylinder with chemical reaction and bioconvection

Chunyan Liu
Muhammad Usman Khan
Ronnason Chinram
ResearchOpen Access30 Apr 2021
Scientific Reports

Volume: 11, P: 1-21
Left ventricular hypertrophy, abnormal ventricular geometry and relative wall thickness are associated with increased risk of stroke in hypertensive patients among the Han Chinese

Shuxia Wang
Hao Xue
Rutai Hui
Research15 May 2014
Hypertension Research

Volume: 37, P: 870-874
Single-cell sequencing depicts tumor architecture and empowers clinical decision in metastatic conjunctival melanoma

Hanhan Shi
Hao Tian
Xianqun Fan
ResearchOpen Access11 Jun 2024
Cell Discovery

Volume: 10, P: 1-17
Vitamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation

Songling Zhu
Shufen Zhong
Yaguang Zhang
Research23 May 2023
Cellular & Molecular Immunology

Volume: 20, P: 794-807
COVID-19 vaccination boosts the potency and breadth of the immune response against SARS-CoV-2 among recovered patients in Wuhan

Hong Liang
Xuanxuan Nian
Xiao-Ming Yang
ResearchOpen Access09 Dec 2022
Cell Discovery

Volume: 8, P: 1-14
Genetic diversity and population structure analysis of Lateolabrax maculatus from Chinese coastal waters using polymorphic microsatellite markers

Wei Wang
Chunyan Ma
Lingbo Ma
ResearchOpen Access27 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways

Yiguo Qiu
Lifei Tao
Bo Lei
ResearchOpen Access25 Aug 2016
Scientific Reports

Volume: 6, P: 1-15
Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway

Zhihua Xing
Zian Xia
Yang Wang
ResearchOpen Access28 Jan 2016
Scientific Reports

Volume: 6, P: 1-14
Runx2-Modified Adipose-Derived Stem Cells Promote Tendon Graft Integration in Anterior Cruciate Ligament Reconstruction

Xin Zhang
Yong Ma
Yingfang Ao
ResearchOpen Access08 Jan 2016
Scientific Reports

Volume: 6, P: 1-15
A SARS-CoV-2 antibody retains potent neutralization against Omicron by targeting conserved RBM residues

Chunyan Yi
Zhiyang Ling
Bing Sun
Correspondence29 Mar 2022
Cellular & Molecular Immunology

Volume: 19, P: 647-649
Rett mutations attenuate phase separation of MeCP2

Chunyan Fan
Honglian Zhang
Falong Lu
CorrespondenceOpen Access16 Jun 2020
Cell Discovery

Volume: 6, P: 1-4

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