The β-cell microcapsules prepared by the microfluidic electrospray method were transplanted into the omentum pouch of mice for intelligent release of insulin to treat diabetes. Studies have shown that microcapsules can encapsulate cells while allowing nutrients and metabolites to enter and exit. This ability helps protect cells, improve cell activity, and reduce inflammation. In addition, the β-cell microcapsules can intelligently release insulin. The constructed living cell biosystem was further demonstrated its potential as artificial islets to be transplanted into diabetic mice omentum pouch to control blood glucose levels and thus treat diabetes of mice.
- Xiaoyu Liu
- Yunru Yu
- Ling Li
