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In this article, authors explore the potential of photoelectrochemical systems for chemical separations, showing that low solar efficiency materials can be viable and cost-effective for water treatment and resource recovery, offering a potentially broader design space than traditional photoelectrochemistry applications.

Nanomagnets are very promising structures for magnetic data storage. However, it is found that during exposure to ambient oxygen for processing, a nanomagnet develops a sidewall oxide layer that is detrimental for its magnetic properties. The problem can be solved by deposition of a metal layer (aluminium) that reduces and almost eliminates the problem.

Here the authors show that rehabilitating nuclear speckles, membraneless organelles involved in mRNA processing and gene regulation, can boost protein quality control and reduce toxic protein buildup, as well as ameliorate models of diseases like tauopathy and retinal degeneration.

Filamentous fungi often grow in porous environments with multiphase flow. Now it is shown that these fungi can actively induce multiphase flow and mobilize trapped fluid phases in porous media.

The function of DNMT1 (DNA methyltransferase 1) in these subsets of immature, migrating cortical inhibitory interneurons is not fully understood. This study shows that DNMT1 regulates cortical development by orchestrating the migration of postmitotic SST+ interneurons and their signaling to cortical progenitors, with implications for proper cortical architecture and function.

The analysis of radial velocity variations of O-type stars in the Small Magellanic Cloud reveals a large fraction of close binaries, suggesting that binary physics also plays a prominent role in the low-metallicity environment of the distant Universe.

Cangkrama et al. show that tumor cells from various cancer types use the mitochondrial trafficking protein MIRO2 and nanotubes to transfer mitochondria into surrounding fibroblasts, thereby inducing cancer-associated fibroblast differentiation and subsequent tumor growth.

Quantum dot spin qubits in Si can be controlled using micromagnet-based electric-dipole spin resonance, but experiments have been limited to small 1D arrays. Here the authors address qubit control in 2D Si arrays, demonstrating low-frequency control of qubits in a 2 x 2 array using hopping gates.

Using 7T resting-state functional MRI data, the authors investigate the effective connectivity of basal forebrain areas in a transdiagnostic sample of patients with anxiety and depression and healthy controls.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Here, the authors report the characterization of stable few-layer PdSe₂ transistors encapsulated in hexagonal boron nitride, showing field effect mobilities up to 700 cm²/Vs at room temperature and signatures of an 8-fold spin-valley degeneracy of the magnetotransport quantum oscillations at cryogenic temperatures.

Label-free and non-destructive infrared near-field microscopy was used to investigate single nanoscale photoswitchable lipid vesicles in water, revealing their chemistry, switching speed and shape transitions below the diffraction limit of light.

Bilayer graphene has been shown to host fractional quantum Hall states. Here, the authors observe the fractional quantum Hall states at quarter- and half-filled Landau levels and the alternation of anti-Pfaffian and Pfaffian phases at half fillings.

The study reveals that a low complexity linker in DNAJB chaperones mediates intramolecular interactions, inducing an autoinhibited state with reduced function, and stabilises the DNAJB–Hsc70 complex by acting as an Hsc70 pseudo-substrate.

Planet-induced flares on HIP 67522, a 17 million-year-old G dwarf star with two known close-in planets, were detected.

Zhang et al. show that genetically simulated IL-6 inhibition is associated with a reduced risk of cardiovascular disease and no increase in infection risk, supporting the use of emerging pharmacological treatments targeting IL-6 rather than its receptor.

The authors highlight inconsistencies and divergencies in the literature reporting data on indirect calorimetry for studies on whole-body energy homeostasis, and propose harmonization of standards to facilitate data comparison and interpretation across different datasets.

Parkinson’s disease (PD) involves toxic protein buildup and energy failure in neurons. Continuously breathing low-oxygen air protected mice from PD-like neuronal loss and reversed symptoms, even after they began, suggesting that hypoxia may protect neurons.

Preventing endosomal damage sensing or using lipids that create reparable endosomal holes reduces inflammation caused by RNA–lipid nanoparticles while enabling high RNA expression.

The presence of a charge order state in underdoped YBCO raises the question of the interplay between this phase and the superconducting one. Here, the authors characterize this material’s phase diagram through specific heat and magnetic measurements, providing strong constrains to theoretical models.

Understanding molecule-surface interactions is key to neat on-surface synthesis of functional nanomaterials. Here, the authors measure interactions of metal surface atoms with CO-terminated tips to reveal their nature and reliable adsorption sites.

Spin ice compounds have localised excitations that behave as magnetic monopoles which move by hopping from site to site, creating a chain of spins. Here the authors show that the hyperfine coupling between electron and nuclear spins is an important part of the mechanism underlying monopole motion.

Material from the Hokioi crater on asteroid Bennu experienced space weathering and suggests microcratering plays a more active role on carbonaceous bodies than initially thought, according to a study of OSIRIS-REx asteroid return samples.

The pathogenic bacterium Pseudomonas aeruginosa can be found in vacuoles and cytoplasm within infected cells. Here, Schator et al. show that extracellular bacteria use a type-III secretion system to induce Ca²⁺ influx into host cells and promote vacuole escape of intracellular bacteria and in vivo dissemination.

β-PdBi2 superconducting properties have been known about since the 1950s, with various works since then indicating the possibility of multiple superconducting gaps and unconventional superconductivity. However, so far only a single gap s-wave superconductivity was detected. Here, using tunnelling spectroscopy under an applied magnetic field, Powell et al observe a transition from s-wave to nodal pairing.

The hydrogen plasma-enabled reduction mechanisms of iron oxide, including reducing species and the rate-controlling process, are identified by observing real-time magnetite nanoparticle morphology changes via nanoscale operando plasma TEM.

A ferroelectric semiconductor field-effect transistor, which uses the two-dimensional ferroelectric semiconductor α-In₂Se₃ as a channel material, could offer enhanced capabilities compared with conventional ferroelectric field-effect transistors in non-volatile memory applications.

An amphiphilic mimotope vaccine can be used in tandem with Food and Drug Administration (FDA)-approved CD19 CAR-T cell products.

Strong light-matter coupling has been realized at the level of single atoms and photons throughout most of the electromagnetic spectrum, except for the THz range. Here, the authors report a THz-scale transport gap, induced by vacuum fluctuations in carbon nanotube quantum dot through the deep strong coupling of a single electron to a THz resonator.

Exciton–lattice interactions suppress thermal noise through vibration isolation, enabling unconventional solitonic superfluorescence at unusually high temperatures in lead halide perovskites.

Flores et al. show that brain-penetrant eIF2B agonists suppress ISR activation in cellular and mouse models of ALS and reduce ISR biomarkers in humans, enabling further clinical studies of ISR inhibition in individuals with neurological diseases

To bypass the limitations of detergents, Ren et al. developed peptide scaffolds that extract membrane proteins directly into lipid nanodiscs, preserving the native environment for structural and functional studies of previously inaccessible membrane protein complexes

Describing the properties of high harmonic photons is challenging due to the complexity of XUV spectroscopy. Here the authors use the photon statistics of the transmitted infrared laser photons to characterize the XUV photon flux without the need of XUV spectrometers.

Pathology-oriented multiplexing (PathoPlex) represents a framework for widespread access to multiplexed imaging and computational image analysis of clinical specimens at a relatively high throughput and subcellular resolution.

The morphogenetic events that occur during gastrulation involve dramatic cell- and tissue-level changes. Here they show that propagation of nematic order, leading to long-range spatial correlation, is universally conserved during metazoan embryogenesis.

Manganese complexes have long been utilized by nature to catalyze the oxygen evolution reaction (OER) but mirroring their efficiency in artificial electrochemical systems has proven difficult. This study centers on alpha-manganese dioxide (α-MnO₂), which closely mimics natural Mn^IV-O-Mn^III-H_xO motifs, presenting a novel method for manipulating proton coupling within the OER process using an external electric field.

Efficient interconversion between electrical and spin signals is critical for the development of spin-based electronics. While the typical approach is to enhance spin-orbit coupling, this usually results in spin dephasing. Here, Barts, Tenzin, and Sławińska show how slow relaxons in chiral tellurium lead to charge-to-spin conversion efficiency of 50%.

The number of individuals in a given space influences animal interactions and network dynamics. Here the authors identify general rules underlying density dependence in animal networks and reveal some fundamental differences between spatial and social dynamics.

Electrified reactive capture converts CO₂ from carbonate solutions but suffers from low Faradaic efficiency. Here, the authors report a templated synthesis with defined pores and Ni single atoms to accumulate CO₂, achieving 46% energy efficiency to syngas at 300 mA/cm²

Perineural invasion and cancer-induced nerve injury of tumour-associated nerves are associated with poor response to anti-PD-1 therapy, which can be reversed by combining anti-PD-1 therapy with anti-inflammatory interventions.

Chiral superconductors are very rare topological materials. Here, the authors report spontaneous magnetic fields inside the superconducting state and low temperature linear behavior in the superfluid density in LaPt₃P, suggesting a chiral d-wave singlet superconducting state.

Here the authors establish a biochromatic method for ultrafast probe and control of the strong field high harmonic generation process in solid by combining strong mid-infrared and weak terahertz fields.

The collective behaviour of electrons trapped in a two-dimensional plane gives rise to fractional quantum Hall states. Amet et al. now observe previously unseen states in boron-nitride-graphene heterostructures in a strong magnetic field that indicate the formation of composite fermions.

The role of the tumour microenvironment in the response to immune checkpoint inhibitors in metastatic melanoma remains poorly understood. Here, single cell profiling of metastatic melanoma samples identifies associations of the mature dendritic enriched in immunoregulatory molecules subtype with immunotherapy response.

I. Silber et al. discover a two-fold symmetry of the superconducting upper critical field in hexagonal 4Hb-TaS₂ just below T_c, a clear signature of nematic, two-component superconductivity. They further suggest a theoretical model that reconciles the nematic superconductivity with the previously-observed time-reversal-symmetry-breaking in this material.

Silane, which is a precursor to the sandy surfaces of rocky planets and dusty clouds on gas giants, is seen directly in another world—a low-metallicity brown dwarf in which oxidation is slow and gas mixing is fast.

Synthetic receptors are a powerful approach for engineering cell-based therapies that can sense and respond to their environment. Here cytokine receptor domains have been repurposed to develop engineered T cells that can sense and respond to cues associated with cancer or immune dysfunction.