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Showing 1–50 of 671 results

Advanced filters: Author: M Srinivasan Clear advanced filters

Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices

Resistance mutations in BCL-2 reduce the clinical efficacy of venetoclax. DeAngelo et al. show stapled BAD BH3 peptides can retain and even enhance binding to these mutants, offering a structurally informed strategy to overcome this mechanism of cancer drug resistance.

Thomas M. DeAngelo
Utsarga Adhikary
Loren D. Walensky
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-15
Disease-linked regulatory DNA variants and homeostatic transcription factors in epidermis

Here the authors use a range of approaches to examine the interplay between genetic variants linked to risk for polygenic skin diseases and transcription factors (TFs) important for skin homeostasis. The findings implicate dysregulated binding of specific TF families in risk for diverse skin diseases.

Douglas F. Porter
Robin M. Meyers
Paul A. Khavari
ResearchOpen Access25 Sept 2025
Nature Communications

Volume: 16, P: 1-28
Influence of Heterologous Histone on the Synthesis of Cellular and Viral Ribonucleic Acid and Production of Haemagglutinin

A. G. BUKRINSKAYA
A. K. GITELMAN
I. M. SHAPIRO
Research06 Nov 1965
Nature

Volume: 208, P: 557-558
Specificity of the Stereochemical Relationship Between Ribonucleic Acid-Triplets and Amino-Acids

M. G. E. WELTON
S. R. PELC
Research26 Feb 1966
Nature

Volume: 209, P: 870-872
Intrinsic Activity in the Fly Brain Gates Visual Information during Behavioral Choices

Shiming Tang
Mikko Juusola
ResearchOpen Access05 Apr 2010
Nature Precedings

P: 1
Tetrad Analysis by Autoradiography

K. M. MARIMUTHU
S. F. H. THRELKELD
Research01 Jul 1964
Nature

Volume: 203, P: 101-102
Stereochemical Relationship Between Coding Triplets and Amino-Acids

S. R. PELC
M. G. E. WELTON
Research26 Feb 1966
Nature

Volume: 209, P: 868-870
Motion cues provide the bee's visual world with a third dimension

M. Lehrer
M. V. Srinivasan
G. A. Horridge
Research24 Mar 1988
Nature

Volume: 332, P: 356-357
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

Maximilian Zenk
Ujjwal Baid
Spyridon Bakas
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-20
Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

B. Kool
K. Verhaegh
V. Zamkovska
ResearchOpen Access05 Sept 2025
Nature Energy

Volume: 10, P: 1116-1131
Spectrophotometric Method for the Estimation of Vitamin K₃

VANAMALA SATHE
J. B. DAVE
C. V. RAMAKRISHNAN
Research11 Feb 1956
Nature

Volume: 177, P: 276
Honeybees link sights to smells

M. V. Srinivasan
S. W. Zhang
H. Zhu
Research17 Dec 1998
Nature

Volume: 396, P: 637-638
Prior experience enhances pattern discrimination in insect vision

S. W. Zhang
M. V. Srinivasan
Research24 Mar 1994
Nature

Volume: 368, P: 330-332
Is pattern vision in insects mediated by 'cortical' processing?

M. V. Srinivasan
S. W. Zhang
B. Rolfe
Research08 Apr 1993
Nature

Volume: 362, P: 539-540
Ultrasonicated synthesis of 1-(2-hydroxyaryl)-3-(pyrrolidin-1-yl)-prop-2-en-1-ones and their antimicrobial screening

Sharad Shelke
Mahendra Sonawane
Charnshing Gill
ResearchOpen Access09 Feb 2009
Nature Precedings

P: 1
Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

P. I. Schrier
R. Bernards
A. J. van der Eb
Research27 Oct 1983
Nature

Volume: 305, P: 771-775
Power quality improvement and energy management in hybrid microgrids using a dual-optimization approach

S. Joshua Daniel
M. Karpagam
Slim Ben Chaabane
ResearchOpen Access16 Oct 2025
Scientific Reports

Volume: 15, P: 1-19
Correlation between segmental mobility and the location of antigenic determinants in proteins

E. Westhof
D. Altschuh
M. H. V. Van Regenmortel
Research13 Sept 1984
Nature

Volume: 311, P: 123-126
RNA-DNA Hybrids at the Cytological Level

H. A. JOHN
M. L. BIRNSTIEL
K. W. JONES
Research09 Aug 1969
Nature

Volume: 223, P: 582-587
Latest Miocene benthic δ¹⁸O changes, global ice volume, sea level and the ‘Messinian salinity crisis’

David A. Hodell
Kristin M. Elmstrom
James P. Kennett
Research03 Apr 1986
Nature

Volume: 320, P: 411-414
On the astrophysical interpretation of isotope anomalies in meteoritic SiC grains

R. Gallino
M. Busso
C. M. Raiteri
Research22 Nov 1990
Nature

Volume: 348, P: 298-302
p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2⁺ breast cancer that limits trastuzumab deruxtecan efficacy

Hu et al. discovered that the truncated form of human epidermal growth factor receptor 2 (HER2), called p95HER2, drives tumor progression and resistance to the antibody–drug conjugate trastuzumab deruxtecan in HER2⁺ breast cancer. Blocking p95HER2 restores antitumor immunity.

Dong Hu
Xiaoshuang Lyu
Peter C. Lucas
Research27 Jun 2025
Nature Cancer

Volume: 6, P: 1202-1222
Structure of human neutrophil collagenase reveals large S1′ specificity pocket

Travis Stams
John C. Spurlino
Byron Rubin
Research01 Feb 1994
Nature Structural Biology

Volume: 1, P: 119-123
Sedimentation of β-Lactoglobulin (A,B) under Dissociating Conditions in Acid Solution

LILO M. GILBERT
G. A. GILBERT
Research23 Dec 1961
Nature

Volume: 192, P: 1181
A mixed-field formulation for modeling dielectric ring resonators and its application in optical frequency comb generation

Ergun Simsek
Alioune Niang
Curtis R. Menyuk
ResearchOpen Access08 Oct 2025
Scientific Reports

Volume: 15, P: 1-13
Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin

M. Knossow
R. S. Daniels
D. C. Wiley
Research18 Oct 1984
Nature

Volume: 311, P: 678-680
In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

Anu Srinivasan
Kevin A Roth
Kevin J Tomaselli
Research01 Dec 1998
Cell Death & Differentiation

Volume: 5, P: 1004-1016
Leaf venation network evolution across clades and scales

This study reconstructs the evolution of leaf venation networks, describing the transition from fewer, corrugated veins to high vein density and smoother loops. It also suggests herbivory as a potential driver of venation architectural changes.

Ilaine Silveira Matos
Bradley Vu
Benjamin W. Blonder
Research06 Jun 2025
Nature Plants

Volume: 11, P: 1127-1141
A Basic Biological Step?

JOHN O'M. BOCKRIS
Research22 Nov 1969
Nature

Volume: 224, P: 775-777
Messenger Activity of Purified RNA from Rat Liver Nuclei

R. BRENTANI
M. BRENTANI
I. RAW
Research10 Jun 1967
Nature

Volume: 214, P: 1122-1123
Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue

Capillaries are thought to be the main suppliers of oxygen to tissues. Here the authors challenge this view by showing that, at baseline brain activity, half of blood oxygen is extracted from arterioles, whereas capillaries supply an oxygen reserve when neuronal activity is high or cerebral blood flow is decreased.

Sava Sakadžić
Emiri T. Mandeville
David A. Boas
Research08 Dec 2014
Nature Communications

Volume: 5, P: 1-11
Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD

A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

Ahyeon Hwang
Mario Skarica
Matthew J. Girgenti
ResearchOpen Access18 Jun 2025
Nature

Volume: 643, P: 744-754
Activation of a cellular transforming gene in tumours induced by Abelson murine leukaemia virus

Mary-Ann Lane
Dorothy Neary
Geoffrey M. Cooper
Research16 Dec 1982
Nature

Volume: 300, P: 659-661
Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes

Genome-wide association analyses identify new risk loci for heart failure and its subtypes, extending understanding of the underlying biological pathways and disease mechanisms.

Albert Henry
Xiaodong Mo
R. Thomas Lumbers
ResearchOpen Access04 Mar 2025
Nature Genetics

Volume: 57, P: 815-828
Unusual Twinning in Graphite

JOHN M. THOMAS
E. E. GLENDA HUGHES
BRIAN R. WILLIAMS
Research16 Feb 1963
Nature

Volume: 197, P: 682-683
Predominantly Electrochemical Nature of Biological Power-producing Reactions

J. O'M. BOCKRIS
S. SRINIVASAN
Research08 Jul 1967
Nature

Volume: 215, P: 197
Thermoluminescence dates for the Neanderthal burial site at Kebara in Israel

H. Valladas
J. L. Joron
B. Vandermeersch
Research18 Nov 1987
Nature

Volume: 330, P: 159-160
Intensity-dependent quasi-periodic oscillations in the X-ray flux of GX5-1

M. van der Klis
F. Jansen
M. Sztajno
Research18 Jul 1985
Nature

Volume: 316, P: 225-230
Fabrication and operation of a two-dimensional ion-trap lattice on a high-voltage microchip

Microfabricated ion traps offer a promising platform for scalable ion quantum computing systems. Sterling et al.realize a two-dimensional ion-trap lattice on a microchip using a new fabrication method that allows very-high voltages to be applied to the chip, enabling very deep ion traps.

R. C. Sterling
H. Rattanasonti
W. K. Hensinger
Research04 Apr 2014
Nature Communications

Volume: 5, P: 1-6
A search for human influences on the thermal structure of the atmosphere

B. D. Santer
K. E. Taylor
S. Tett
Research04 Jul 1996
Nature

Volume: 382, P: 39-46
c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression

S S Ganguly
L S Fiore
R Plattner
Research05 Sept 2011
Oncogene

Volume: 31, P: 1804-1816
XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries

Siddiqui et al. explore the role of islet-specific XBP1 expression in type 2 diabetes (T2D) and glycemic traits across diverse ancestries. XBP1 eQTL is associated with T2D, beta-cell function, HbA1c and drug response in East and South Asians in whom this variant is common and beta-cell dysfunction is a significant driver of early onset T2D.

Moneeza K. Siddiqui
Theo Dupuis
Ana Viñuela
ResearchOpen Access24 Sept 2025
Communications Medicine

Volume: 5, P: 1-10
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Genome-wide analyses using fetal and parental genotypes identify 40 independent associations influencing placental weight and highlight the role of the fetus in preeclampsia risk and placental growth regulation via insulin signaling.

Robin N. Beaumont
Christopher Flatley
Pål R. Njølstad
ResearchOpen Access05 Oct 2023
Nature Genetics

Volume: 55, P: 1807-1819
Modeling farmer responses to reservoir operation policies using agent based analysis of risk behavior and irrigation adoption

Ehsan Ebrahimi
Mojtaba Shourian
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-18
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
A cytoplasmically transmitted disease of Ceratocystis ulmi

C. M. Brasier
Research15 Sept 1983
Nature

Volume: 305, P: 220-223
Common cervicovaginal sequencing methods result in discordant molecular diagnoses of bacterial vaginosis and reveal strain level effects of Gardnerella vaginalis

Courtney A. Broedlow
Erik Swanson
Nichole R. Klatt
ResearchOpen Access05 Jul 2025
npj Women's Health

Volume: 3, P: 1-12
Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy

Genome-wide association analyses comprising 14,256 cases and 1,199,156 controls and incorporating correlated cardiac magnetic resonance imaging traits provide insights into the molecular etiology of dilated cardiomyopathy.

Sean L. Zheng
Albert Henry
R. Thomas Lumbers
ResearchOpen Access21 Nov 2024
Nature Genetics

Volume: 56, P: 2646-2658
irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein assemblies on RNA

EGF-induced recruitment of UPF1 adjacent to HNRNPC induces splicing surveillance of cell proliferation mRNAs.

Luca Ducoli
Brian J. Zarnegar
Paul A. Khavari
Research26 Mar 2025
Nature

Volume: 641, P: 769-778
Calcium Hydroxide in Sucrose Solution as a Reagent for the Preparation of Water-dispersible Calcium Proteinates

M. SRINIVASAN
P. N. ACHUTAMURTHY
V. SUBRAHMANYAN
Research29 Dec 1962
Nature

Volume: 196, P: 1313-1314

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