Nature Search

Contrasting age-dependent leaf acclimation strategies drive vegetation greening across deciduous broadleaf forests in mid- to high latitudes

This study reports age-dependent negative correlations between temporal changes in maximal leaf area index and growing season length, indicating contrasting leaf acclimation strategies driving vegetation greening in young versus old deciduous broadleaf forests.

Fangyi Wang
Meimei Xue
Xiuzhi Chen
Research08 Sept 2025
Nature Plants

Volume: 11, P: 1748-1758
Impacts of rising atmospheric dryness on terrestrial ecosystem carbon cycle

Atmospheric dryness is increasing as air temperatures rise because of climate change. This Review explores temporal trends and spatial heterogeneity in global atmospheric dryness and the implications for plant growth, productivity and terrestrial carbon cycling.

Wenping Yuan
Jie Tian
Xiuzhi Chen
Reviews07 Oct 2025
Nature Reviews Earth & Environment

P: 1-16
Positional BMP signaling orchestrates villus length in the small intestine

BMP signaling forms an intestinal gradient regulating villus length by balancing cell proliferation with apoptosis to optimize nutrient absorption efficiency across regions.

Xu Wang
Siqi Li
Ye-Guang Chen
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Publisher Correction: The P-loop NTPase RUVBL2 is a conserved clock component across eukaryotes

Meimei Liao
Yanqin Liu
Eric Erquan Zhang
Amendments and CorrectionsOpen Access19 Jun 2025
Nature

Volume: 643, P: E12
The P-loop NTPase RUVBL2 is a conserved clock component across eukaryotes

A study finds that RUVBL2 is a conserved component of eukaryotic circadian clocks and suggests that slow ATPase activity, which was initially discovered in cyanobacteria, is a shared feature of eukaryotic clocks.

Meimei Liao
Yanqin Liu
Eric Erquan Zhang
ResearchOpen Access26 Mar 2025
Nature

Volume: 642, P: 165-173
LensAge index as a deep learning-based biological age for self-monitoring the risks of age-related diseases and mortality

Age is closely related to health, but chronologically defined age often disagrees with biological age. Here, the authors develop an indicator of biological age - LensAge index - to reveal individuals’ aging level, and it can be implemented with smartphones, showing potential for self-monitoring of aging.

Ruiyang Li
Wenben Chen
Haotian Lin
ResearchOpen Access06 Nov 2023
Nature Communications

Volume: 14, P: 1-13
Predictive efficacy and role of 2HG in MGMT promoter methylation in gliomas: a retrospective study based on MRS and mediator variable analysis

Ying Ge
Meimei Yu
Huicong Shen
Research30 Jul 2025
British Journal of Cancer

Volume: 133, P: 1003-1009
Author Correction: CYP72A enzymes catalyse 13-hydrolyzation of gibberellins

Juan He
Qingwen Chen
Guodong Wang
Amendments and Corrections03 Oct 2019
Nature Plants

Volume: 5, P: 1194
Correction: Corrigendum: B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Irene Puga
Montserrat Cols
Andrea Cerutti
Amendments and Corrections21 Jan 2014
Nature Immunology

Volume: 15, P: 205
Cost-effectiveness and cost-utility of a digital technology-driven hierarchical healthcare screening pattern in China

Economic evaluation of utilization of digital technologies for cataract screening remains unknown. Here the authors show that digital hierarchical screening is cost-effective in China and annual screening proved to be the most cost-effective option.

Xiaohang Wu
Yuxuan Wu
Haotian Lin
ResearchOpen Access30 Apr 2024
Nature Communications

Volume: 15, P: 1-11
Machine learning and metagenomics reveal shared antimicrobial resistance profiles across multiple chicken farms and abattoirs in China

A data mining and machine learning approach for improving surveillance reveals clinically relevant antimicrobial resistance profiles across chicken farms, abattoirs and environments in three provinces in China.

Michelle Baker
Xibin Zhang
Tania Dottorini
ResearchOpen Access10 Aug 2023
Nature Food

Volume: 4, P: 707-720
A signalling pathway for transcriptional regulation of sleep amount in mice

Virus-mediated somatic genetics experiments in adult mouse brain identify key roles of LKB1 and SIK3 upstream of HDAC4/5 and CREB in the transcriptional regulation of non-rapid eye movement sleep.

Rui Zhou
Guodong Wang
Qinghua Liu
Research07 Dec 2022
Nature

Volume: 612, P: 519-527
Convergence of resistance and evolutionary responses in Escherichia coli and Salmonella enterica co-inhabiting chicken farms in China

Bacteria in the same environment can share genetic material but the extent to which this influences development of antimicrobial resistance is unclear. Here, the authors investigate the evidence for co-evolution of antimicrobial resistance in bacteria found coexisting in animals and the environment in chicken farms and slaughterhouses in China.

Michelle Baker
Xibin Zhang
Tania Dottorini
ResearchOpen Access05 Jan 2024
Nature Communications

Volume: 15, P: 1-21
Circulating cell-free DNA correlate to disease activity and treatment response of patients with radiographic axial spondyloarthritis

Yun Peng
Yuanhui Wu
Guixiu Shi
ResearchOpen Access02 Jan 2024
Scientific Reports

Volume: 14, P: 1-9
CYP72A enzymes catalyse 13-hydrolyzation of gibberellins

Gibberelins comprise a large number of species, with some being bioactive forms and the others being inactive. The different gibberelin species are interconvertible, and a new subfamily of cytochrome P450 enzymes has now been identified to be responsible for gibberelin deactivation in Brassicaceae.

Juan He
Qingwen Chen
Guodong Wang
Research16 Sept 2019
Nature Plants

Volume: 5, P: 1057-1065
Defect and structural evolution under high-energy ion irradiation informs battery materials design for extreme environments

Defect and structural evolution are critical in determining the stability of battery materials. Here, the authors use high-energy Kr ion irradiation to induce rapid defect and study structural evolution in Li- and Na-layered cathodes to find that Li-layered cathodes are more resilient under irradiation.

Muhammad Mominur Rahman
Wei-Ying Chen
Feng Lin
ResearchOpen Access11 Sept 2020
Nature Communications

Volume: 11, P: 1-13
Automated detection of retinal exudates and drusen in ultra-widefield fundus images based on deep learning

Zhongwen Li
Chong Guo
Haotian Lin
Research03 Aug 2021
Eye

Volume: 36, P: 1681-1686
Risk factors of restenosis after paclitaxel-coated balloon treatment in symptomatic intracranial atherosclerotic disease

Yingkun Chen
Kaiyue Dong
Ju Han
ResearchOpen Access24 May 2025
Scientific Reports

Volume: 15, P: 1-8
Mitsugumin 53 drives stem cell differentiation easing intestinal injury and inflammation

Yumeng Pei
Meng Fang
Rui-Ping Xiao
ResearchOpen Access11 Jun 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-13
HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

Patients infected with human immunodeficiency virus (HIV) have profoundly dysfunctional T and B cell populations. Cerutti and colleagues show that HIV-infected macrophages form long-range conduits that deliver the immunosuppressive HIV protein Nef to distal B cells, inhibiting their function.

Weifeng Xu
Paul A Santini
Andrea Cerutti
Research02 Aug 2009
Nature Immunology

Volume: 10, P: 1008-1017
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

Immunoglobulin class-switch recombination can be induced by the secreted factors BAFF and APRIL. Cerutti and colleagues show that the receptor TACI conveys such signals via the adaptor MyD88 to induce class-switch recombination.

Bing He
Raul Santamaria
Andrea Cerutti
Research01 Aug 2010
Nature Immunology

Volume: 11, P: 836-845
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Follicular T cells provide help to B cells to elicit antibody responses. Cerutti and colleagues show that neutrophils provide help to marginal-zone B cells that produce T cell–independent antibodies.

Irene Puga
Montserrat Cols
Andrea Cerutti
Research25 Dec 2011
Nature Immunology

Volume: 13, P: 170-180
Investigating the mechanism of Gentiopicroside in rheumatoid arthritis through network pharmacology, molecular docking, and experimental validation

Rongyue Jing
Yueyue Chen
Suling Wu
ResearchOpen Access06 Jun 2025
Scientific Reports

Volume: 15, P: 1-18
Efficacy and safety of KN026, a bispecific anti-HER2 antibody, in combination with KN046, an anti-CTLA4/PD-L1 antibody, in patients with advanced HER2-positive nonbreast cancer: a combined analysis of a phase Ib and a phase II study

Dan Liu
Jifang Gong
Lin Shen
ResearchOpen Access19 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-10
Noninvasive early prediction of preeclampsia in pregnancy using retinal vascular features

Yuxuan Wu
Lixia Shen
Haotian Lin
ResearchOpen Access05 Apr 2025
npj Digital Medicine

Volume: 8, P: 1-9
Modification of Different Pulps by Homologous Overexpression Alkali-Tolerant Endoglucanase in Bacillus subtilis Y106

Meimei Wang
Jian Du
Jian Zhao
ResearchOpen Access12 Jun 2017
Scientific Reports

Volume: 7, P: 1-10
Targeting AKT induced Ferroptosis through FTO/YTHDF2-dependent GPX4 m6A methylation up-regulating and degradating in colorectal cancer

Ge Zhang
Wunan Mi
Yingjie Zhang
ResearchOpen Access15 Dec 2023
Cell Death Discovery

Volume: 9, P: 1-13
Artificial intelligence manages congenital cataract with individualized prediction and telehealth computing

Erping Long
Jingjing Chen
Yizhi Liu
ResearchOpen Access28 Aug 2020
npj Digital Medicine

Volume: 3, P: 1-10
DR-region of Na⁺/K⁺ ATPase is a target to treat excitotoxicity and stroke

Meimei Shi
Lei Cao
Jin-Song Bian
ResearchOpen Access18 Dec 2018
Cell Death & Disease

Volume: 10, P: 1-15
Natural forest growth and human induced ecosystem disturbance influence water yield in forests

Natural forest growth does not decrease water yield and forest responses to human disturbances and management interventions vary with ecosystem complexity, according to a global meta-analysis that includes 496 watersheds and spans 25 years.

Zhen Yu
Xiuzhi Chen
Xiang Zhao
ResearchOpen Access27 Jun 2022
Communications Earth & Environment

Volume: 3, P: 1-8
A Novel Direct Factor Xa Inhibitory Peptide with Anti-Platelet Aggregation Activity from Agkistrodon acutus Venom Hydrolysates

Meimei Chen
Xiaohui Ye
Yi Kong
ResearchOpen Access02 Jun 2015
Scientific Reports

Volume: 5, P: 1-11
The relationship of polluted air and drinking water sources with the prevalence of systemic lupus erythematosus: a provincial population-based study

Jiaqi Chen
Wenqiang Qu
Lingyun Sun
ResearchOpen Access20 Sept 2021
Scientific Reports

Volume: 11, P: 1-11
Safety and activity of WX-0593 (Iruplinalkib) in patients with ALK- or ROS1-rearranged advanced non-small cell lung cancer: a phase 1 dose-escalation and dose-expansion trial

Yuankai Shi
Jian Fang
Huaize Geng
ResearchOpen Access28 Jan 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-10
Automatic identification of triple negative breast cancer in ultrasonography using a deep convolutional neural network

Heng Ye
Jing Hang
Dong Zhang
ResearchOpen Access14 Oct 2021
Scientific Reports

Volume: 11, P: 1-10
Hypertension combined with atherosclerosis increases the risk of heart failure in patients with diabetes

Lili Wu
Jingli Gao
Jiang Hong
Research15 Dec 2023
Hypertension Research

Volume: 47, P: 921-933
Clinical and laboratorial outcome of different age-onset systemic lupus erythematosus patients in Jiangsu, China: a multicentre retrospective study

Lihui Wen
Ziyan Chen
Lingyun Sun
ResearchOpen Access23 Jun 2022
Scientific Reports

Volume: 12, P: 1-8
TMED10-mediated unconventional secretion of IL-33 regulates intestinal epithelium differentiation and homeostasis

Yang Wang
Meimei Huang
Liang Ge
Correspondence08 Jan 2024
Cell Research

Volume: 34, P: 258-261
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system

Yangyang Zhu
Hao Zhang
Longping Wen
Research14 Sept 2022
Cell Death & Differentiation

Volume: 30, P: 168-183
DefectTrack: a deep learning-based multi-object tracking algorithm for quantitative defect analysis of in-situ TEM videos in real-time

Rajat Sainju
Wei-Ying Chen
Yuanyuan Zhu
ResearchOpen Access20 Sept 2022
Scientific Reports

Volume: 12, P: 1-14
Deep learning from “passive feeding” to “selective eating” of real-world data

Zhongwen Li
Chong Guo
Haotian Lin
ResearchOpen Access30 Oct 2020
npj Digital Medicine

Volume: 3, P: 1-9
Pathogenic BALB/c mice infection model for evaluation of mpox countermeasures

Lin Cheng
Wenqi Huang
Zheng Zhang
CorrespondenceOpen Access13 Oct 2024
Cell Discovery

Volume: 10, P: 1-3
The cisplatin-induced lncRNA PANDAR dictates the chemoresistance of ovarian cancer via regulating SFRS2-mediated p53 phosphorylation

Hao Wang
Lei Fang
Peiling Li
ResearchOpen Access30 Oct 2018
Cell Death & Disease

Volume: 9, P: 1-15
Efficacy of synthetic surfactant (CHF5633) bolus and/or lavage in meconium-induced lung injury in ventilated newborn rabbits

Yaling Xu
Xiaojing Guo
Bo Sun
Research14 Jun 2022
Pediatric Research

Volume: 93, P: 541-550

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