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Showing 1–50 of 54 results

Advanced filters: Author: Yonghui Zhao Clear advanced filters

TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease

TNF inhibitors show clinical benefits for Behçet’s disease (BD), but the underlying molecular insights are still unclear. Here the authors use both patient samples and mouse genetic models to show that TNF inhibitors may target a metabolite/TRPM2/calcium signaling positive feedback loop of inflammation amplification for dampening vasculitis in BD.

Menghao Zhang
Na Kang
Wenjie Zheng
ResearchOpen Access26 Oct 2024
Nature Communications

Volume: 15, P: 1-17
Helical-caging enables single-emitted large asymmetric full-color circularly polarized luminescence

Circularly polarised luminescence (CPL) is essential for asymmetric synthetic photochemistry. Here, the authors integrate white quantum dots with chiral nematic liquid crystal or liquid crystal polymer to achieve single-emitted tuneable full-colour or white CPL for enantioselective polymerization.

Yajie Zhou
Yaxin Wang
Taotao Zhuang
ResearchOpen Access04 Jan 2024
Nature Communications

Volume: 15, P: 1-8
Atomic Ga triggers spatiotemporal coordination of oxygen radicals for efficient water oxidation on crystalline RuO₂

Advancements in proton-exchange membrane water electrolyzers rely on developing oxygen evolution reaction catalysts with high activity and stability. Here, the authors report a method to enhance the spatiotemporal coordination of oxygen radicals in a Ru-based catalyst for improved performance.

Haifeng Wang
Chao Lin
Wei Luo
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-13
Structural and functional analysis of human pannexin 2 channel

The PANX2 channel is involved in skin homeostasis and neuronal development, but the molecular basis of channel function remains largely unknown. Here, the authors provide detailed analysis of the structure, function, and pharmacology of human PANX2.

Zhihui He
Yonghui Zhao
Peng Yuan
ResearchOpen Access27 Mar 2023
Nature Communications

Volume: 14, P: 1-10
Maternal adiposity and perinatal and offspring outcomes: an umbrella review

This umbrella review of 194 observational meta-analyses and 748 interventional studies finds that maternal adiposity is associated with 12 adverse perinatal and offspring outcomes. Maternal weight loss interventions can only reduce some of these effects.

Ziyi Yang
Gengchen Feng
Zi-Jiang Chen
Research11 Oct 2024
Nature Human Behaviour

Volume: 8, P: 2406-2422
Atomic-scale strain engineering of atomically resolved Pt clusters transcending natural enzymes

Strain engineering is promising for improving catalytic capability of biocatalysts, but it is challenging to modify the atomic-scale strain for specific enzyme-like reactions. Here, the authors report the biocatalysts with atomically-resolved Pt clusters laminated on PdAu nanocrystals and show that the tensile strains contribute to the enzyme-like activities greater than that of natural enzymes.

Ke Chen
Guo Li
Xiao-Dong Zhang
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-18
Author Correction: TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease

Menghao Zhang
Na Kang
Wenjie Zheng
Amendments and CorrectionsOpen Access03 Jan 2025
Nature Communications

Volume: 16, P: 1
Lifelike agility and play in quadrupedal robots using reinforcement learning and generative pre-trained models

A key challenge in robotics is leveraging pre-training as a form of knowledge to generate movements. The authors propose a general learning framework for reusing pre-trained knowledge across different perception and task levels. The deployed robots exhibit lifelike agility and sophisticated game-playing strategies.

Lei Han
Qingxu Zhu
Zhengyou Zhang
Research05 Jul 2024
Nature Machine Intelligence

Volume: 6, P: 787-798
Automated high-throughput genome editing platform with an AI learning in situ prediction model

A large number of cell disease models with pathogenic SNVs are needed. Here the authors report an automated high-throughput platform to perform the genome editing process from gRNA design to the analysis of the editing results; they characterise in situ base editing outcomes.

Siwei Li
Jingjing An
Meng Wang
ResearchOpen Access30 Nov 2022
Nature Communications

Volume: 13, P: 1-11
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2

A broad-range human antibody with neutralizing activity against various coronaviruses, including SARS-CoV-2, targets a unique epitope within the highly conserved S2’ site and the fusion peptide of the spike protein that is exposed during interaction with the host cell. The pan-coronavirus antibody protects mice against infection with SARS-CoV-2 and HCoV-OC43 following prophylactic and therapeutic treatment.

Xiaoyu Sun
Chunyan Yi
Bing Sun
Research30 Jun 2022
Nature Microbiology

Volume: 7, P: 1063-1074
Synthesis of orthogonally assembled 3D cross-stacked metal oxide semiconducting nanowires

Orthogonal self-assembly of amphiphilic diblock copolymers and polyoxometallates followed by calcination allows the formation of cross-stacked multilayer 3D arrays of tungsten oxide nanowires.

Yuan Ren
Yidong Zou
Yonghui Deng
Research02 Dec 2019
Nature Materials

Volume: 19, P: 203-211
HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N⁶-methyladenosine

Cells respond to heat shock with transcriptional and translational adaptations but how HSP90 inhibition alters the heat shock proteome is largely unclear. Here, the authors analyze proteome changes upon HSP90 inhibition and show that an m⁶A-mediated mechanism contributes to the heat shock-induced upregulation of DNAJB4.

Weili Miao
Lin Li
Yinsheng Wang
ResearchOpen Access09 Aug 2019
Nature Communications

Volume: 10, P: 1-12
Metagenome-wide association of gut microbiome features for schizophrenia

Gut microbiome has been linked to neurogenerative diseases. Here, the authors present a metagenome-wide association study of schizophrenia (SZ) in human cohorts and identify SZ-associated specific gut-brain functional modules and pathways including SCFAs and neurotransmitters.

Feng Zhu
Yanmei Ju
Xiancang Ma
ResearchOpen Access31 Mar 2020
Nature Communications

Volume: 11, P: 1-10
Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters

Potassium channels and membrane potential may influence macrophage function during inflammation. Here the authors show that the Kir2.1 potassium channel affects macrophage metabolism by altering cell surface retention of nutrient transporters and subsequently regulates inflammatory disease responses.

Weiwei Yu
Zhen Wang
Di Wang
ResearchOpen Access21 Jun 2022
Nature Communications

Volume: 13, P: 1-18
Mechanisms of the regulation of ester balance between oxidation and esterification in aged Baijiu

Yonghui Deng
Ayuan Xiong
Qing Zheng
ResearchOpen Access13 Oct 2020
Scientific Reports

Volume: 10, P: 1-7
Unveiling the drivers of environmental performance by investigating the Nexus of energy, economic complexity and institutional quality in G7 nations

Yonghui Cai
Xingyu Li
Yumin Huang
ResearchOpen Access29 Mar 2025
Scientific Reports

Volume: 15, P: 1-18
Research on application of thin-walled metal pressure device in large deformation tunnel

Like Zhao
Xueqi Zhang
Wujian Xiao
ResearchOpen Access27 Mar 2025
Scientific Reports

Volume: 15, P: 1-15
Bipolar Hemiarthroplasty should not be selected as the primary option for intertrochanteric fractures in elderly patients

Jincheng Huang
Yanxin Shi
Hongkai Lian
ResearchOpen Access16 Mar 2020
Scientific Reports

Volume: 10, P: 1-5
Pressure-induced superconductivity in MoP

Zhenhua Chi
Xuliang Chen
Zhaorong Yang
ResearchOpen Access30 May 2018
npj Quantum Materials

Volume: 3, P: 1-7
Alleviating NIR-II emission quenching in ring-fused fluorophore via manipulating dimer populations for superior fluorescence imaging

This study presents a dimer-dominated emission quenching mechanism that enhances second near-infrared emission in ring-fused fluorophores by reducing dimer populations for high-resolution vascular fluorescence imaging.

Xiaofei Miao
Mingxuan Jia
Wenbo Hu
ResearchOpen Access04 Mar 2025
Light: Science & Applications

Volume: 14, P: 1-11
An improved bistable stochastic resonance method and its application in early bearing fault diagnosis

Yonghui Zhao
Anqi Jiang
Xiaoyang Gu
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Defects in Silicene: Vacancy Clusters, Extended Line Defects and Di-adatoms

Shuang Li
Yifeng Wu
Yonghao Zhao
ResearchOpen Access26 Jan 2015
Scientific Reports

Volume: 5, P: 1-7
Estimation of land-surface evaporation at four forest sites across Japan with the new nonlinear complementary method

Zhipin Ai
Qinxue Wang
Deni Eer
ResearchOpen Access19 Dec 2017
Scientific Reports

Volume: 7, P: 1-8
Experimental demonstration of a reconfigurable electro-optic directed logic circuit using cascaded carrier-injection micro-ring resonators

Yonghui Tian
Zilong Liu
Lin Yang
ResearchOpen Access25 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
Study on energy absorption characteristics of the corrugated straight tube flip type energy absorption device

Jianzhuo Zhang
Fengnian Zhao
Yonghui Xiao
ResearchOpen Access19 Feb 2025
Scientific Reports

Volume: 15, P: 1-23
Identification of a biomass unaffected pale green mutant gene in Chinese cabbage (Brassica rapa L. ssp. pekinensis)

Yonghui Zhao
Shengnan Huang
Hui Feng
ResearchOpen Access11 May 2022
Scientific Reports

Volume: 12, P: 1-10
Assessment of the responses of soil pore properties to combined soil structure amendments using X-ray computed tomography

Yonghui Yang
Jicheng Wu
Chun Chen
ResearchOpen Access12 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Diurnal cycle and seasonal variation of cloud cover over the Tibetan Plateau as determined from Himawari-8 new-generation geostationary satellite data

Huazhe Shang
Husi Letu
Jiancheng Shi
ResearchOpen Access18 Jan 2018
Scientific Reports

Volume: 8, P: 1-8
Prediction of human population responses to toxic compounds by a collaborative competition

Crowdsourcing analysis improves computational prediction of cytotoxic responses in humans.

Federica Eduati
Lara M Mangravite
Julio Saez-Rodriguez
ResearchOpen Access01 Sept 2015
Nature Biotechnology

Volume: 33, P: 933-940
Selection of renewable energy development path for sustainable development using a fuzzy MCDM based on cumulative prospect theory: the case of Malaysia

Taikun Li
Hong Wang
Yonghui Lin
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-16
SNORD1C maintains stemness and 5-FU resistance by activation of Wnt signaling pathway in colorectal cancer

Yonghui Liu
Chengwen Zhao
Xudong Wang
ResearchOpen Access14 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-11
Cobalt carbide nanoprisms for direct production of lower olefins from syngas

Lower olefins are hydrocarbons that are widely used in the chemical industry, and can be generated from syngas by the ‘Fischer–Tropsch to olefins’ process; here, a new catalyst is described that can generate lower olefins from syngas with high selectivity, with little formation of undesirable methane.

Liangshu Zhong
Fei Yu
Hui Wang
Research05 Oct 2016
Nature

Volume: 538, P: 84-87
Author Correction: Plasma extracellular vesicle long RNA profiles in the diagnosis and prediction of treatment response for breast cancer

Yonghui Su
Yuchen Li
Jiong Wu
Amendments and CorrectionsOpen Access15 Mar 2022
npj Breast Cancer

Volume: 8, P: 1
GABA_AR-PPT1 palmitoylation homeostasis controls synaptic transmission and circuitry oscillation

Jia Tong
Jingjing Gao
Lihao Ge
ResearchOpen Access18 Dec 2024
Translational Psychiatry

Volume: 14, P: 1-12
Development of a nomogram for deep vein thrombosis in patients with tibial plateau fractures based on systemic Immune-inflammation index

He Ling
Wencai Li
Zhao Huang
ResearchOpen Access12 Oct 2024
Scientific Reports

Volume: 14, P: 1-13
A chemical approach for global protein knockdown from mice to non-human primates

Xiuyun Sun
Jun Wang
Yu Rao
ResearchOpen Access05 Feb 2019
Cell Discovery

Volume: 5, P: 1-13
Forecasts for the concentration of petroleum gas leakage diffusion under different liquid level heights of a sealing ring of sizeable floating roof tank

Yonghui Wei
Wenfeng Wu
Min Guo
ResearchOpen Access09 Nov 2022
Scientific Reports

Volume: 12, P: 1-14
Plasma extracellular vesicle long RNA profiles in the diagnosis and prediction of treatment response for breast cancer

Yonghui Su
Yuchen Li
Jiong Wu
ResearchOpen Access10 Dec 2021
npj Breast Cancer

Volume: 7, P: 1-10
Thermal fluid fields reconstruction for nanofluids convection based on physics-informed deep learning

Yunzhu Li
Tianyuan Liu
Yonghui Xie
ResearchOpen Access22 Jul 2022
Scientific Reports

Volume: 12, P: 1-23
Single-cell transcriptomics reveals intestinal cell heterogeneity and identifies Ep300 as a potential therapeutic target in mice with acute liver failure

Jie Yin
Ziming Zhao
Yonghui Zhang
ResearchOpen Access25 Jul 2023
Cell Discovery

Volume: 9, P: 1-23
A comprehensive AI model development framework for consistent Gleason grading

Huo, Ong et al. present a comprehensive workflow to try to overcome key limitations in prior approaches for artificial intelligence (AI)-assisted prostate cancer Gleason grading. Their approach incorporates automated quality control, efficient annotation and visualization, and pathologist-AI interaction.

Xinmi Huo
Kok Haur Ong
Soo Yong Tan
ResearchOpen Access09 May 2024
Communications Medicine

Volume: 4, P: 1-13
Fatal Community-acquired Pneumonia in Children Caused by Re-emergent Human Adenovirus 7d Associated with Higher Severity of Illness and Fatality Rate

Zhiwu Yu
Zhiwei Zeng
Qiwei Zhang
ResearchOpen Access16 Nov 2016
Scientific Reports

Volume: 6, P: 1-12
Structural insights into HetR−PatS interaction involved in cyanobacterial pattern formation

Hai-Xi Hu
Yong-Liang Jiang
Cong-Zhao Zhou
ResearchOpen Access18 Nov 2015
Scientific Reports

Volume: 5, P: 1-11
CircCYP24A1 hampered malignant phenotype of renal cancer carcinoma through modulating CMTM-4 expression via sponging miR-421

Xiaorong Wu
Jiale Zhou
Wei Xue
ResearchOpen Access26 Feb 2022
Cell Death & Disease

Volume: 13, P: 1-11
Research on the comparison of impact resistance characteristics between energy absorption and conventional hydraulic columns in fluid–solid coupling

Jianzhuo Zhang
Hao Guo
Fengnian Zhao
ResearchOpen Access25 Nov 2023
Scientific Reports

Volume: 13, P: 1-20
On enhancing the noise-reduction performance of the acoustic lined duct utilizing the phase-modulating metasurface

Yang Ou
Yonghui Zhao
ResearchOpen Access13 Dec 2023
Scientific Reports

Volume: 13, P: 1-20
Exome sequencing analysis on products of conception: a cohort study to evaluate clinical utility and genetic etiology for pregnancy loss

Chen Zhao
Hongyan Chai
Peining Li
Research26 Oct 2020
Genetics in Medicine

Volume: 23, P: 435-442
PROTAC-induced BTK degradation as a novel therapy for mutated BTK C481S induced ibrutinib-resistant B-cell malignancies

Yonghui Sun
Xingwang Zhao
Yu Rao
Correspondence06 Jun 2018
Cell Research

Volume: 28, P: 779-781
Characteristics of serum metabolites in sporadic amyotrophic lateral sclerosis patients based on gas chromatography-mass spectrometry

Rui Jia
Qiaoyi Chen
Jingxia Dang
ResearchOpen Access21 Oct 2021
Scientific Reports

Volume: 11, P: 1-11
Genetic variations in adiponectin levels and dietary patterns on metabolic health among children with normal weight versus obesity: the BCAMS study

Ge Li
Ling Zhong
Shan Gao
Research29 Oct 2021
International Journal of Obesity

Volume: 46, P: 325-332

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