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Artificial intelligence and the future of evidence-based medicine

Generative artificial intelligence is transforming how clinical evidence is generated and applied in clinical care by enabling real-time data integration, dynamic trial design and personalized decision support.

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Acknowledgements

The views expressed in this Comment are those of the authors and not necessarily those of the NIHR or Department of Health and Social Care.

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Correspondence to Tien Yin Wong.

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Competing interests

Imperial College London, the employer of L.T.C. and A.M., has received funding for research on AI via the NIHR Applied Research Collaboration NW London.

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Tudor Car, L., Wong, T.Y., Majeed, A. et al. Artificial intelligence and the future of evidence-based medicine. Nat. Health (2026). https://doi.org/10.1038/s44360-025-00002-z

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