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Developing transparent, evidence-based allocation strategies for essential medicines is especially critical in low- and middle-income countries, where affordability and equity challenges are most acute.
PREZODE is a global One Health initiative, involving scientists, communities, governments and practitioners, to prevent zoonotic epidemics and pandemics.
GLP-1 receptor agonists can be classified as transitional longevity therapeutics, but more evidence is needed to assess their direct and indirect effects.
Twenty-five years after its first public repository was established, the PhysioNet resource for biomedical and clinical data has enabled tens of thousands of research papers. Further efforts are ongoing to advance secure data sharing, community engagement and scalable research infrastructure.
Removing race and ethnicity from clinical algorithms is feasible, but it requires careful evaluation of algorithmic changes and systemic efforts to address underlying disparities.
Human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) have declined in recent years, but continued surveillance and research is needed to understand this trend and mitigate future zoonotic threats.
With almost all of the Sustainable Development Goals not being achieved amid declining global solidarity, countries would be better served by regional development goals.
Screening for the sexually transmitted infections chlamydia and gonorrhoea in gay, bisexual and other men who have sex with men drives antimicrobial resistance without reducing incidence and prevalence.
Targeted screening for steatotic liver disease screening should be linked up with existing cardiometabolic care structures, enabling scalable and collaborative disease management.
Disease modelling for low-income settings often lacks reliable data, which leads to modelled outputs that contrast with empirical data and local knowledge
Religious beliefs, practices and institutions shape health behaviours and the provision of care, and should be more effectively integrated with evidence-based medicine.
Current systems of cancer research marginalize knowledge from low- and middle-income countries, where most future cancer cases will occur, by privileging high-income country evidence and often overlooking local expertise and context-specific needs.
