Volume 1 Issue 5, May 2026

Online harms are an urgent societal challenge, but governments should prepare teenagers to responsibly use digital technology.

Shared leadership between global and African partners is essential to expand early-phase trial capacity in sub-Saharan Africa and ensure that medical innovation serves the populations most affected by disease.

Assessing the effect of climate extremes on maternal and infant health is hindered by gaps in exposure data, vulnerability assessments and integration of sociobehavioural dimensions.

Genomics Thailand offers lessons for middle-income countries that want to advance cost-effective precision health.

This Perspective describes the Colombo Call to Action, a roadmap for countries in South-East Asia to accelerate diabetes prevention and care, aiming to close treatment gaps and meet 2030 coverage targets by setting urgent and actionable priorities.

In a prospective multi-centre cohort in China, people living in areas of high soil selenium had a 35% increased risk of incident diabetes over a 3-year study period, with a stronger effect seen for men.

Nationwide analysis of 30,086 confirmed Oropouche virus cases in Brazil between 2014 and 2025 shows that rural municipalities had over 11-fold-higher incidence than urban areas and identifies demographic, ecological and climatic factors influencing transmission, offering insights for targeted surveillance and control.

Data from 12,608 pregnancies across 7 African countries and a simulation model suggest that the total number of malaria-exposed pregnancies across sub-Saharan Africa exceeded 13 million in 2023, and that current prevention measures avoided more than 2 million malaria-related anaemia cases.

Pregnant women exposed to cumulative days of high temperature saw a twofold-increased risk of gestational diabetes in a time-series study of 8,796 such cases in Barcelona between 2011 and 2022.

Using an integrative spatial Bayesian framework that merges high-resolution environmental pesticide risk modelling with comprehensive cancer registry data, this analysis reveals spatial patterns of pesticide exposure and liver tissue-derived molecular signatures across Peru, establishing links between pesticide usage and cancer insurgence at the national scale.

This scoping review examines previous experience in performing silent evaluations of clinical AI applications, collecting evidence from 75 studies on implementation features and the sociotechnical context.