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This journal collection focuses on advancements in cardiovascular tissue regeneration through bioengineering approaches, cell-base therapies, and other advanced technologies. Advancements in technologies and biomaterials to promote regeneration include organoid models, microphysiological systems, 3D bioprinting, tissue engineering, and engineered biomaterials that can be validated with preclinical models. Multi-omics and computational biology associated with disease pathologies can lead to fundamental insights with translational relevance. Therapies based on stem cells, small molecules, and other biologics that promote tissue regeneration are also of particular interest. The collection emphasizes the important role of intercellular interactions among cells/tissues and their surrounding extracellular matrix on disease pathology and tissue regeneration. These technologies, therapeutic strategies, and fundamental insights are applied to the treatment of cardiovascular diseases such as myocardial infarction, atherosclerosis, stroke, vascular dysfunction, and aortic aneurysm.
This Collection aims to integrate knowledge from fundamental biology, applied technologies, and preclinical models, offering new insights and potential therapeutic strategies to promote cardiovascular tissue regeneration.