Clinical Sciences articles for Germany

Time frame: 1 May 2025 - 30 April 2026

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Count: 619

Article ‘Count’ for Clinical Sciences.

Journal Count Share
1 0.08
Dendritic Cell-Inspired Triple-Functional Biocatalysts with Atomic Iron Sites To Eradicate Drug-Resistant Bacteria and Biofilms 0.08
3 0.99
Phagocyte-Inspired Supramolecular Self-Assembly Design of Abiotic Cell-Mimics for Pathogen Recognition and Eradication 0.08
Bio-lubrication in insect joints: A lesson for designing a low-friction micro-bearing 0.75
Fluorescent mapping of osteocyte-driven bone formation at pre-osteocyte and mature osteocyte lacunae 0.17
1 0.29
A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration 0.29
3 2.10
Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain 1.00
Integrating Vibrio natriegens for Photon Manipulation in Living Lighting Devices 1.00
Lattice‐Reconstructed Ru‐Clusters on FeOOH‐Based Self‐Adaptive Artificial Peroxisome with Programmed ROS Regulation for Infectious and Inflammatory Chronic Wounds 0.10
1 0.17
Bi-allelic mutations in FASTKD5 are associated with cytochrome c oxidase deficiency and early- to late-onset Leigh syndrome 0.17
1 0.10
Topical Therapy and Vulvar Malignancy Risk in Lichen Sclerosus: A Large Propensity-Matched Study 0.10
1 0.14
Growth differentiation factor 11 attenuates photoaging through ferroptosis pathway in SZ95 sebocytes 0.14
5 0.37
Electrical impedance tomography-guided PEEP and mortality of patients with the acute respiratory distress syndrome: The EITVent randomized clinical trial 0.02
Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study 0.08
The Effectiveness of Isoniazid Preventive Treatment among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis. 0.05
Physiological Consequences of Breathing Effort According to the Mode of Ventilation During Acute Hypoxemic Respiratory Failure. 0.03
Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3). 0.19
6 4.60
ATR-FTIR Spectroscopy of Saliva and Machine Learning as a Screening Test for Sjögren Disease 0.46
Simultaneous Elemental and Molecular Mass Spectrometry of Tattoo Inks and Tattooed Skin Biopsies: A Novel Laser Ablation-Based Technique for Tattoo Pigment Analysis 1.00
Development of a Novel Homogeneous Liposome-Based One-Step Assay for SARS-CoV-2 Antibody Detection in Human Serum Based on Fluorescent Liposomes and Complement Activity 1.00
p-Cresol and C. difficile: A Love-Hate Story Revealed by Raman Spectroscopy 1.00
Glycan-Induced Transchelation of Gadolinium from Magnetic Resonance Imaging Contrast Agent-Complexes 1.00
Toward “Receive-Only” Nuclear Magnetic Resonance Complementary Metal-Oxide-Semiconductor Microcoil Arrays for High-Throughput Analysis of Environmental Samples 0.14
5 2.63
Recirculation quantified by Trans-ECMO thermodilution to predict mixed venous oxygenation during V-V ECMO: an in vivo porcine study. 0.91
Mechanical power and the association with postoperative impaired oxygenation and pulmonary complications in orthopedic patients: post hoc analysis of a cluster factorial randomized trial. 0.15
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications: A retrospective cohort study. 0.13
Individualized Flow-Controlled versus Pressure-Controlled Ventilation in Cardiac Surgery: A Randomized Controlled Trial. 0.86
Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain. 0.59
6 4.47
Bio-Propelled Stomatocyte Nanomotors with Glutathione-Responsiveness for Osteoarthritis Treatment 0.08
Rapid RASER MRI 0.75
Dual-Channel Fluorescence Assays with Supramolecular Host-Dye Reporter Pairs for Membrane Activity Mapping of Peptides 1.00
Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms 0.75
Non‐Amphiphilic Antimicrobial Polymers 1.00
Modular Synthesis of Dendritic Oligo‐Glycerol Cationic Surfactants for Enhanced Antibacterial Efficacy 0.89
1 0.11
Tranexamic Acid Timing and Mortality Impact After Trauma 0.11
3 0.79
Association Between Body Composition and Cardiometabolic Outcomes : A Prospective Cohort Study. 0.69
High Tibial Osteotomy for Medial Compartment Knee Osteoarthritis : A Randomized Trial With Parallel Preference Arm. 0.05
Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery. 0.05
5 1.19
Longitudinal Phenotypic Trajectories in GNAO1-Related Disorders: Defining Disease Progression and Clinical Profiles 0.04
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort 0.65
Intranasal Seletracetam in a Patient with Reading Epilepsy: First‐in‐Human Use to Prevent Reflex Seizures 0.20
The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype 0.18
The Spectrum of Neurologic Phenotypes Associated With scpiNUS1/i/scp Pathogenic Variants: A Comprehensive Case Series 0.12
3 1.18
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.05
Perioperative Outcomes in Open Versus Minimally Invasive Gastrectomy For Gastric Cancer: A European Multicenter Study Based on the GASTRODATA Registry. 0.13
Timing of Antibiotic Prophylaxis Prior to Abdominal Surgery Has No Impact on Infectious Complications: A Retrospective Matched Cohort Study. 1.00
30 12.41
Response of ultrasound-assessed synovitis to baricitinib, in monotherapy and combined with methotrexate, compared with etanercept in rheumatoid arthritis: a randomised, international, multicentre trial 0.06
Frequency and characteristics of axial involvement in psoriatic arthritis: results from the International Multicentre AXIS Study 0.18
Human blood vessel organoids recapitulate key mechanisms of transition from vasculopathy to fibrosis in systemic sclerosis 0.95
Neutrophil transcriptomics in SLE reveals intrinsic disease signatures, shared ex vivo adaptation, and transcriptional reset after CAR T-cell therapy 0.11
Inhibition of the type I interferon receptor pathway protects against muscle weakness induced by dermatomyositis serum 0.03
Risk score for early mortality to stratify for intensive SSc therapy in the EUSTAR network: the RESIST score 0.10
An app-based nonpharmacological intervention improves patient-reported disease activity, functionality, and quality of life in patients with axial spondyloarthritis: a randomised controlled trial 1.00
Progression from at-risk state to clinical and severe systemic lupus erythematosus involves molecular dysregulations potentially reversible by biologics: implications for early diagnosis and treatment 0.04
The epigenomic landscape of primary tissues in osteoarthritis 0.67
A phase 2, randomised, placebo-controlled study of guselkumab in adults with new-onset or relapsing giant cell arteritis 0.14
The incidence of interstitial lung disease in patients with systemic sclerosis: rate, risk factors and prognostic implications in a EUSTAR cohort analysis (CP 133) 0.14
Identification of novel fibroblast subsets in diffuse cutaneous systemic sclerosis 1.00
Inflammation rather than anticitrullinated protein antibodies is associated with cardiovascular mortality in RA: insights from rheumatoid arthritis and coronary artery disease cohorts 0.22
A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis 0.26
Effects of clofutriben, a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, on the efficacy and toxicity of prednisolone in patients with polymyalgia rheumatica: a single-blind controlled trial with sequential cohorts 0.42
Entheseal tissue signature in response to IL-17A inhibition in psoriatic arthritis: results from the EBIO entheseal biopsy study 0.88
SLE classification criteria item relationships: implications on SLE as a disease entity 0.60
Collagen-binding integrin α11β1 contributes to joint destruction in arthritic hTNFtg mice 0.89
A glossary of signs and symptoms of giant cell arteritis 0.10
AYLo study–elevated relapse risk and dysregulated proinflammatory signalling in giant cell arteritis patients with mosaic loss of the Y chromosome 1.00
Highly selective tyrosine kinase 2 inhibition with zasocitinib (TAK-279) improves outcomes in patients with active psoriatic arthritis: a randomised phase 2b study 0.06
Comparative risk of incident malignancies in rheumatoid arthritis patients treated with Janus kinase inhibitors or bDMARDs: observational data from the German RABBIT register 1.00
Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis 1.00
Exploring the limit of image resolution for human expert classification of vascular ultrasound images in giant cell arteritis and healthy subjects: the GCA-US-AI project 0.21
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland 0.03
CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue 0.03
Spatial multiomics decipher fibroblast–macrophage dynamics in systemic sclerosis 0.33
Radiographic structural damage in axial spondyloarthritis: is there a preferred way to quantify progression over time? Comparison of blinded versus unblinded mSASSS scoring 0.85
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1 0.08
Enhanced B cell and complement cascade gene signatures in patients with neuropsychiatric systemic lupus erythematosus 0.03
14 6.59
High‐resolution deep learning DIXON MRI of the sacroiliac joints is non‐inferior to standard MRI in patients with suspected axial Spondyloarthritis 0.92
18F‐Fluorodeoxyglucose Positron Emission Tomography Imaging Assessment within a Randomized Controlled Trial in Giant Cell Arteritis 0.17
Prediction of Relapse and Glucocorticoid Dependence in Eosinophilic Granulomatosis With Polyangiitis: Findings From a Large European Cohort 0.21
Decision tree analysis as a preliminary evidence‐based tool for identifying the syndrome of undifferentiated recurrent fever in children compared with hereditary recurrent fevers and periodic fever, aphthosis, pharyngitis and adenitis syndrome 0.11
The impact of non‐steroidal anti‐inflammatory drugs on radiographic spinal progression in patients with axial spondyloarthritis: 10‐year results from an inception cohort 0.94
Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation 1.00
Transition from psoriasis to psoriatic arthritis is characterized by distinct alterations in peripheral blood Tc17, Th17 and CD4+ TEM cells 1.00
Efficacy and Safety of ABBV-154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo-Controlled Trial 0.07
Incidence of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis Treated With scpJAK/scp Inhibitors Compared With Biologic Disease‐Modifying Antirheumatic Drugs: Data From an International Collaboration of Registries 0.07
Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the scpHLA/scp Class scpII/scp Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis 0.12
Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study 0.75
Antifibrotic effects of specific targeting of the 5-hydroxytryptamine 2B receptor (5-HT2BR) in murine models and ex vivo models of scleroderma skin 0.62
A randomized, double‐blind, placebo‐controlled trial of abatacept for the treatment of relapsing, non‐severe, granulomatosis with polyangiitis 0.03
Peripheral blood gene expression profiling shows prognostic significance for the course of interstitial lung disease in systemic sclerosis 0.57
7 2.55
Biosignatures of cognitive basic symptoms mark a distinct neurodevelopmental pathway to schizophrenia 0.61
Predictive models for ataxia progression and conversion in spinocerebellar ataxia type 1 and 3 0.10
Memory deficits of MDMA users are linked to cortical thinning related to 5-HT receptor densities 0.18
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease 0.22
Combined genomics and proteomics unveils elusive variants and vast aetiologic heterogeneity in dystonia 0.47
Alzheimer and cardiovascular genetic scores and cognition: the FINGER randomized controlled trial 0.09
Modelling fragile X-associated neuropsychiatric disorders in young inducible 90CGG premutation mice 0.88
6 2.50
Parallel Endografting And Chimney Endovascular (PEACE) registry outcomes in emergency repair of complex abdominal aortic aneurysms 0.07
Performance indicators for organ donation and transplantation programmes in Europe: modified Delphi consensus study 0.06
Treatment strategies for Boerhaave syndrome: multinational retrospective cohort study 0.22
Oncological safety of portal vein embolization without prior tumour clearance in the future liver remnant followed by one-stage hepatectomy for bilateral colorectal liver metastases 0.16
Endoscopic and surgical treatment options for gastroparesis: systematic review and network meta-analysis 1.00
Effect of virtual reality on pain and stress in children during Kirschner-wire removal after fracture treatment: a randomized clinical trial 1.00
1 0.04
Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression 0.04
3 1.55
Mechanism-guided identification of antidepressant G protein-coupled receptor drug targets 0.05
Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease 0.98
Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage 0.51
4 0.83
The DanRI regulatory system in uropathogenic Escherichia coli subverts neutrophil responses 0.67
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase 0.05
A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation 0.09
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease 0.03
4 1.08
Blood-flow restriction resistance training improves skeletal muscle mitochondrial capacity and cardiovascular risk factors in type 2 diabetes 0.84
Gut microbiome-adipose crosstalk modulates soluble IL-6 receptor influencing exercise responsiveness in glycemic control and insulin sensitivity 0.05
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes 0.09
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication 0.10
1 0.05
Engineered intestinal crypt geometry uncovers YAP1-dependent fetal-to-adult transition 0.05
1 0.22
A phage-selective trigger hints at an SOS-independent mechanism of prophage induction by oxidative stress 0.22
1 0.87
Covert triage during the COVID-19 pandemic: A qualitative analysis of rationing in intensive care 0.87
2 0.10
Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: a Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial. 0.07
Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes from the STORM-PE Trial. 0.04
5 0.40
Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries 0.08
Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM) 0.11
The three-gene Xpert Host Response signature for pediatric tuberculosis screening: A prospective diagnostic accuracy study 0.04
Projecting the Impact and Costs of Near Point-of-Care Tuberculosis Screening Assays in Community-based Active Case Finding 0.15
Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study 0.02
8 3.58
The Influence of Older Age on RBC Transfusion Decisions in ICU Patients. 0.02
Location of In-Hospital Cardiac Arrest: An Updated Analysis of Epidemiology, Emergency Response, and Outcomes. 0.21
Conversion From Venovenous to Venoarterial or Hybrid Extracorporeal Membrane Oxygenation: Analysis From the Extracorporeal Life Support Organization Registry. 0.13
The Role of Perceived Urgency and Barriers in Using Emergency Medical Care for Sepsis: A German-Wide, Representative Survey Using Case Vignettes. 1.00
Extracorporeal Membrane Oxygenation Complications Are Not Causal for Mortality in Patients With Infarct-Related Cardiogenic Shock: A Mediation Analysis of the Extracorporeal Life Support in Infarct-Related Cardiogenic Shock (ECLS-SHOCK) Trial. 1.00
Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study. 0.02
Digital Twins to Evaluate the Risk of Ventilator-Induced Lung Injury During Airway Pressure Release Ventilation Compared With Pressure-Controlled Ventilation. 0.20
Multicomponent Communication Intervention to Support Family Members of the Critically Ill: A Controlled Pre-Post Study. 1.00
3 0.67
Cocaine pollution alters the movement and space use of Atlantic salmon (Salmo salar) in a large natural lake 0.05
Conscious awareness determines whether a second learning session disrupts or facilitates earlier learning 0.17
Programmed seasonal brain shrinkage in the common shrew via water loss without cell death 0.45
2 0.13
Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma 0.03
NGN3 oscillatory expression controls the timing of human pancreatic endocrine differentiation 0.10
7 0.97
Global, Regional, and National Estimates of Undiagnosed Diabetes in Adults: Findings From the 2025 IDF Diabetes Atlas. 0.06
Interlaboratory Evaluation of Multiplex Autoantibody Assay Performance in the Islet Autoantibody Standardization Program 2024 Workshop. 0.14
Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. 0.14
Effect of Semaglutide on Insulin Sensitivity and Cardiometabolic Risk Factors in Adolescents With Obesity: The STEP TEENS Study. 0.18
Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial). 0.27
Plasma Metabolome, Long-term Body Weight Change, and Type 2 Diabetes in U.S. Individuals. 0.05
Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis. 0.14
2 0.06
Mobilization of the Environmental Toxicant Chlorpyrifos during Weight Loss and Its Impact on Liver and Adipose Tissue Metabolism in Mice 0.03
Mobilization of the environmental toxicant chlorpyrifos during weight loss and its impact on liver and adipose tissue metabolism in mice. 0.03
1 0.22
Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders 0.22
7 2.94
Prenatal exposure to 33 endocrine-disrupting chemicals and pubertal development at age 9 in Spain 0.08
Disposable plastic-alcohol leachates as emerging Neurotoxicants: Evidence for the mir-330-3p/Acsl1 pathway in cognitive performance 0.09
Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis 0.20
A comprehensive assessment of contaminant exposure in an endangered tern population 1.00
Impact of summer heat on male children's physiological responses during football training 0.75
Adolescent exposure to benzophenone ultraviolet filters: cross-sectional associations with obesity, cardiometabolic biomarkers, and asthma/allergy in six European biomonitoring studies 0.07
Joint effects of environmental and neighborhood socioeconomic factors on cognitive function in the Heinz Nixdorf Recall Study 0.75
4 2.70
Transport and Survival of Marine Tracer Phages in Topsoil at Field Conditions 1.00
Assessment of Population Relevance of Endocrine-sensitive Apical Endpoints in Fish Chronic Studies Using Individual-Based Models 0.60
Phthalate and Nonphthalate Plasticizer Exposure among Children of Korea, Thailand, Indonesia, and Bangladesh: Occurrences and Risk Comparison 0.10
Beyond Estrogenicity: A Comparative Assessment of Bisphenol A and Its Alternatives in In Vitro Assays Questions Safety of Replacements 1.00
3 1.49
C-reactive protein and cardiovascular risk in the general population 0.39
Ischaemic conditioning: a renaissance with wider perspectives? 1.00
Optical coherence tomography- vs angiography-guided coronary stent implantation in calcified lesions: the ILUMIEN IV trial 0.10
2 0.25
Intestinal Ultrasound Scan in Acute Severe Ulcerative Colitis in Children: A Multicenter Prospective Study on Behalf of the Porto Inflammatory Bowel Disease Working Group of European Society for Paediatric Gastroenterology Hepatology and Nutrition 0.13
From Gut Feeling to Gray Matter: Mapping Defecation Urgency in Irritable Bowel Syndrome 0.13
14 4.36
Tryptophan depletion generates hyper-reactive portal neutrophils in alcoholic liver disease 0.97
Novel insights into autoimmune gastritis: clinical profile and gastric neoplastic risk from an international multicentre study 0.07
Oncological impact of universal endoscopic submucosal dissection for large Barrett’s cancers 0.06
<atl>Novel imyo/i -inositol to butyrate fermentation pathway in the prevalent human gut species iDysosmobacter welbionis,/i a bacterium associated with improved metabolic and liver health</atl> 0.04
Targeting MLCK1 uncouples immune checkpoint inhibitor-induced colitis from antitumour immunity 0.03
Gut microbiota predict development of postdischarge diabetes mellitus in acute pancreatitis 0.62
Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis 0.05
A20-mediated KEAP1 ubiquitination orchestrates hepatocyte ferroptosis to ameliorate autoimmune hepatitis 0.06
First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia 0.30
Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial 0.09
Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort 0.22
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies 0.01
CagA-dependent Hobit+ gastric tissue-resident memory T cells confer full protection from Helicobacter pylori reinfection 0.93
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD 0.91
4 0.48
ECM1 produced by hepatic stellate cells serves as a gatekeeper of liver homeostasis in hepatic fibrosis. 0.06
Original research: Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency. 0.19
Multimodal transcriptomics identifies metallothionein as a novel pathway in primary sclerosing cholangitis. 0.14
Comparison of diagnostic accuracy and utility of non-invasive tests for clinically significant liver disease in a general population with metabolic dysfunction. 0.09
2 1.86
Three-Dimensional Anatomical Data Generation Based on Artificial Neural Networks* 1.00
Exploring the Virtual Pivot Point in Unilateral Transfemoral Amputee Locomotion: Implications for Prosthetic Development 0.86
1 0.04
Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma 0.04
1 0.21
Malaria amidst the COVID-19 pandemic in Gabon: an application of autoregressive integrated moving average (ARIMA) models within an interrupted time series (ITS) framework to hospital-based data 0.21
6 3.38
Movement behaviors, psychosocial well-being and childhood obesity: the IDEFICS/I.Family cohort 0.25
Sex-specific longitudinal associations between repeatedly measured movement behaviours and adiposity measures in school-aged children: a compositional data analysis approach 0.03
The long-term effect of metabolic bariatric surgery on innate immune cell phenotype and function 0.10
Detecting monogenic obesity: a systematic exome-wide workup of over 500 individuals 1.00
High fat diet induces gastric production of fibroblast growth factor 23 (FGF23) 1.00
Pre-post changes of integrated care needs in patients undergoing bariatric surgery 1.00
2 0.20
Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes 0.17
High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Diabetes 0.03
10 4.07
Antipsychotic Efficacy and Safety of LB-102 in the Treatment of Adults With Acute Schizophrenia 0.05
Age at First Attention-Deficit/Hyperactivity Disorder Diagnosis and Educational Outcomes 0.54
Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression 1.00
Clozapine After 1 Failed Antipsychotic Drug Trial in First-Episode Psychosis 0.05
Psychological and Psychosocial Interventions for People With Schizophrenia and Co-Occurring Substance Use Disorders 0.96
Mental Disorders as a Risk Factor of Acute Coronary Syndrome 0.01
Measures of General Intelligence and Risk for Alcohol Use Disorder 0.05
Occurrence of Psychosis and Bipolar Disorder in Individuals With Attention-Deficit/Hyperactivity Disorder Treated With Stimulants 0.03
Framework for Brain-Derived Dimensions of Psychopathology 0.38
Simvastatin as Add-On Treatment to Escitalopram in Patients With Major Depression and Obesity 1.00
4 1.77
Preoperative Hemoglobin A1C, Glycemic Status, and Postoperative Outcomes in General Surgery 0.54
Biological vs Synthetic Mesh in Laparoendoscopic Inguinal Hernia Repair 1.00
Diagnostic Accuracy of Imaging in Assessing Nonviability of Disappearing Colorectal Liver Metastasis 0.04
Obesity Treatment With Bariatric Surgery vs GLP-1 Receptor Agonists 0.20
6 0.70
Oral Nalbuphine in Idiopathic Pulmonary Fibrosis–Associated Cough 0.13
Intraoperative Driving Pressure–Guided High PEEP vs Standard Low PEEP for Postoperative Pulmonary Complications 0.10
Discordance in Creatinine- and Cystatin C–Based eGFR and Clinical Outcomes 0.07
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.01
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction 0.31
Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension 0.08
5 1.50
A luminescent reporter assay to quantify SORL1 ectodomain shedding and Retromer-dependent endosome recycling activity 0.13
Differential modulation of polycystin-2 gain-of-function channels by cysteine-reactive compounds, amphiphilic substances, and S4-S5 linker mutations 1.00
Dominant-negative NARS1 R534∗ mutation causes wild-type subunit poisoning and heterodimer predominance in cells 0.11
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice 0.06
Covalent Binding of Thioredoxin to TXNIP is Required for Diet-induced Insulin Resistance in the Liver 0.20
2 0.20
Surgical Treatment of Recurrent Lumbar Disc Herniation: To Fuse or Not To Fuse: A Single-Center Analysis of Clinical and Radiographic Characteristics and Surgical Outcomes of 450 Patients. 0.13
High Failure Rates of Polyethylene Glenoid Components in Stemless Anatomic Total Shoulder Arthroplasty for Primary and Secondary OA. 0.07
11 3.51
Real-world impact of treatment on growth in children with X-linked hypophosphatemia 0.08
International real-world study on osilodrostat efficacy and safety in adrenal Cushing syndrome 0.25
Personalized Drug Screening and Risk Assessment in Patient-Derived Gastroenteropancreatic Neuroendocrine Neoplasms 0.48
Patient-Reported Outcomes in Palopegteriparatide-Treated Adults with Hypoparathyroidism: PaTH Forward Trial Extension 0.06
Secukinumab in Moderate-to-Severe Graves Orbitopathy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study 0.80
Persistent Renin Suppression After Unilateral Adrenalectomy for Primary Aldosteronism: Implications for Adverse Outcome? 1.00
Rapid and Sustained Response of Biochemically Uncontrolled Acromegaly to Once-Daily Oral Paltusotine Treatment 0.17
Near-Adult Height Outcomes in Patients Treated With rhIGF-1 for Severe Growth Failure: Real-World IGFD Registry Data 0.14
MCT8 Deficiency in Females 0.19
High-Throughput Proteomics and Immunohistochemistry of Orbital Connective Tissue in Graves’ Orbitopathy 0.32
Arginine-Vasopressin Dynamics in Relation to Food Intake and 8-Week Intranasal Oxytocin Treatment in Adults With Obesity 0.03
8 1.87
Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis 0.07
Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK–STAT signaling 0.05
Boosting SIV-specific CD8+ T cell responses prior to ART interruption extends time to SIVmac239 rebound 0.10
Secretory kinase FAM20C triggers adipocyte dysfunction inciting insulin resistance and inflammation in obesity 0.12
A pathogenic variant of AMOT leads to isolated X-linked congenital hydrocephalus due to N-terminal truncation 0.63
The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation 0.08
Gut-specific histamine 3 receptor signaling orchestrates microglia-dependent resolution of peripheral inflammation 0.74
Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease 0.10
4 0.41
Immune profiling links autoimmune hepatitis to human herpesvirus 6 and relaxin receptor antigens 0.07
Transcription of HIV-1 is heterogenous among authentic latent CD4+ T cell clones 0.07
Salmonella-superspreader hosts require gut regulatory T cells to maintain a disease-tolerant state 0.13
Neonatal microbiota colonization primes maturation of goblet cell–mediated protection in the pre-weaning colon 0.14
11 1.84
Quantitative regression of qFibrosis with resmetirom: Exploratory histologic endpoints from the MAESTRO-NASH phase III clinical trial 0.09
Kupffer cell plasticity regulates hepatic immunity in mycobacterial infection 0.97
Incidence and implications of abstinence-induced recompensation in alcohol-related cirrhosis 0.17
Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis 0.16
Predicting hepatic decompensation using non-invasive tests in a contemporary multicentre cohort of patients with cACLD 0.09
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials 0.04
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.08
Phase II INTEGRIS-PSC trial of bexotegrast, an αvβ6/αvβ1 integrin inhibitor, in primary sclerosing cholangitis 0.04
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.01
Identification and validation of RIPK3 as a novel biomarker to predict outcomes in patients with acutely decompensated cirrhosis 0.13
Safety and efficacy of elafibranor in primary sclerosing cholangitis: The ELMWOOD phase II randomized-controlled trial 0.07
15 5.90
Treatment Monitoring and Outcome Prediction in Invasive Aspergillosis Using Immunologic Markers 0.15
Tracking Plasmodium knowlesi Through Fecal DNA for Monitoring Zoonotic Transmission in Wild Macaques Across Southeast and South Asia 0.02
RNA Polymerase III suppresses varicella zoster virus in human neurons 0.44
Efficient sensing of a four-segmented Rift Valley fever virus vaccine candidate by human monocytes 0.83
Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV 0.03
<atl>Safety and immunogenicity of a iKlebsiella pneumoniae/i tetravalent bioconjugate vaccine (Kleb4V) administered to healthy adults: A first time in human phase I/II randomised and controlled study</atl> 0.13
Foreign Combatants Wounded in Ukraine colonized by Extensively Drug-Resistant organisms: A Potential Source of Global Dissemination 0.32
Plasma Proteomics Reveals Distinct Signatures in Occult and Microfilaremic Loa loa Infections 0.76
Impact and Cost-effectiveness of Regular Self-digital Anorectal Examination on Syphilis Among Gay, Bisexual, and Other Men Who Have Sex With Men: A Mathematical Modeling Study 0.08
Bacterial and Viral Coinfections in Adult Patients Hospitalized With COVID-19 Throughout the Pandemic: A Multinational Cohort Study in the EuCARE Project 0.32
Risk assessment of Oropouche virus transmission by mosquitoes in Europe 1.00
Host Determinants for the Spread of Panton-Valentine Leukocidin–Positive Staphylococcus aureus in Sub-Saharan Africa 0.50
SARS-CoV-2 Infection of Human Lung Air-Liquid Interface Cultures Reveals Basal Cells as Relevant Targets 1.00
Evaluating the Diagnostic Utility of 16S Oxford Nanopore Technology Sequencing in Patients With Central Nervous System Infections and Its Usefulness in Antimicrobial Stewardship 0.27
iStreptococcus pyogenes/i Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock Syndrome in Rural Japan 0.03
8 4.59
Controlling spatio-temporal sequences of neural activity by local synaptic changes 0.33
Motor-to-limbic design of direct synaptic communication between dopamine neurons in the midbrain 0.67
Dopamine and temporal discounting: revisiting pharmacology and individual differences 0.88
Social Reward Learning Deficits and Concordant Brain Alterations in Rats Overexpressing Disrupted-in-Schizophrenia 1 (DISC1) 0.78
First application of a novel brain template: Motor training improves cortico-cerebellar connectivity in cerebellar ataxia 0.71
Stress-responsive neuronal ensembles and β-adrenergic signaling in the basolateral amygdala modulate the infra-limbic cortical activity and govern the delayed stress-induced fear extinction deficit. 0.14
Exploring Neural Dynamics in the Auditory Telencephalon of Crows using Functional Ultrasound Imaging 1.00
The Functional Anatomy of Nociception: Effective Connectivity in Chronic Pain and Placebo Response 0.08
5 2.57
Neurophysiological sensitivity to envelope and pulse timing interaural time differences in cochlear implanted rats with different hearing experiences 0.43
Profound neuronal differences during exercise‐induced hypoalgesia between athletes and non‐athletes revealed by functional near‐infrared spectroscopy 1.00
A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes 0.86
Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres 0.04
Impact of medial calcification on arterial mechanics and haemodynamics 0.25
1 0.15
Minimally invasive resection of non–small cell lung cancer after chemoimmunotherapy: A multicenter study in academic hospitals 0.15
1 0.02
Adolescents’ Relationships With Their Parents and Peers as Mediators Between Economic Circumstances and Emotional Symptoms: A Multicountry Longitudinal Analysis 0.02
5 1.13
Impact of early treatment of psoriasis on disease recurrence—Results from the STEPIn study 0.07
Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension 0.28
Efficacy and Safety of Ruxolitinib Cream for the Treatment of Moderate to Severe Chronic Hand Eczema: Results From a 16-Week, Multicenter, Randomized, Double-Blind Study 0.11
Real-world treatment patterns in patients with generalized pustular psoriasis (GPP): 0.57
Establishment of standardized definitions and a core set of outcome characteristics following hidradenitis suppurativa surgery developed by an expert Delphi consensus 0.10
3 2.96
Advanced Molecular Tweezers Effectively Target Membranes Lacking Choline Headgroups for Broad-Spectrum Antiviral Efficacy 1.00
Actifensin Evolution in the Human Oral Cavity over the Past 100,000 Years 0.96
Automated Glycan Assembly of iPorphyromonas gingivalis/i Lipopolysaccharide Epitopes for Vaccine Design 1.00
4 0.76
Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of CONFIDENCE Randomized Trial 0.20
Impact of Vutrisiran on Cardiac Biomarkers in Patients With Transthyretin Amyloidosis With Cardiomyopathy From HELIOS-B 0.06
Vutrisiran Improves Survival and Reduces Cardiovascular Events in ATTR Amyloid Cardiomyopathy HELIOS-B 0.10
Effect of Empagliflozin on the Mechanisms Driving Erythropoiesis and Iron Mobilization in Patients With Heart Failure The EMPEROR Program 0.40
4 0.55
Effect of Finerenone on Morbidity and Mortality in CKD. 0.17
Microbes and Glomerular Filtration Rate in Health and CKD in Mice. 0.04
Biomarkers of Kidney Failure and All-Cause Mortality in CKD. 0.05
Use of eGFR Slope Thresholds as End Point Components in a Kidney Disease Progression Hierarchical Composite End Point. 0.29
3 0.39
Tattoos and risk of cutaneous melanoma and non-melanoma skin cancer in France 0.20
Basal cell carcinoma risk prediction in survivors of childhood cancer 0.09
Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study 0.10
16 7.47
Insights from the BLISS-LN Phase 3 study of biomarker associations with kidney response to belimumab in lupus nephritis 0.08
The calcimimetic etelcalcetide restores cardiac function in chronic hyperphosphatemia via calcium sensing receptor–cAMP activation 1.00
Tubular cell-specific platelet-derived growth factor-B drives formation of fibrogenic niches in kidney fibrosis 1.00
A population-based, regression discontinuity analysis examined the effects of nationwide alerting for acute kidney injury on health care and patient outcomes 0.07
A Drosophila model for Dent’s disease type 1 revealed impaired endoplasmic reticulum export of Cubilin as pathogenic mechanism 0.71
Sodium glucose transporter 2 inhibition maintains kidney antibacterial response by decreasing complement C1q 1.00
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy 0.09
Sodium-glucose co-transporter 2 inhibition improves age-dependent kidney microvascular rarefaction 0.19
Sodium glucose cotransporter 2 inhibition does not improve active lupus nephritis in MRLlpr/lpr mice 0.14
Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function 0.83
Patient anti-PLA2R1 autoantibodies cause membranous nephropathy in human PLA2R1 transgenic mice 1.00
Syntaxin 3 regulates apical membrane integrity in proximal tubule epithelial cells and prevents Fanconi syndrome development 0.06
Mineralocorticoid receptor inhibition in parietal epithelial cells prevents focal segmental glomerulosclerosis and crescentic glomerulonephritis. 0.07
A stronger type I interferon signature distinguishes ANCA-associated vasculitis phenotypes and predicts kidney prognosis 0.09
Causal assessment of CKD-MBD biomarker alterations on CKD progression through a g-formula analysis in the EQUAL Study 0.13
Regulation of podocyte surface proteins by the enzyme A Disintegrin And Metalloproteinase 10 (ADAM10) 1.00
1 0.10
Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation 0.10
26 8.54
Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study 0.28
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.03
A longitudinal DNA methylation atlas and its link to brain structure and mental health 0.37
A ventral striatal learning signal reflecting individual differences in the success of fear extinction 0.70
Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis 0.26
Transcriptome-informed brain cartography of polygenic risk and association with brain structure in major psychiatric disorders 0.07
Psychotropic medications and their interactions with subcortical brain volume in bipolar disorder: An ENIGMA mega-analysis 0.19
Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide 0.38
Delay discounting correlates with depression but does not predict relapse after antidepressant discontinuation 0.25
Common alterations of whole and subregion-specific amygdala intrinsic functional connectivity across psychiatric disorders: a meta-analysis 0.23
Prediction of postoperative delirium after cardiac surgery by the interplay between preoperative plasma p-tau181 and IL-6 and heart-brain axis related factors: results from the prospective observational study FINDERI 0.97
MRI-derived estimation of biological aging in patients with affective disorders in a 9-year follow-up - a prospective marker of future recurrence 0.86
Deliberate self-harm and suicide in individuals with cannabis-related hospital contacts in Ontario, Canada 0.03
Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium 0.19
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.39
Relapse risk prediction in patients with first-episode bipolar disorder: development, external validation, and pharmacotherapy associations of a machine learning model 0.13
GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy 0.24
Development and validation of a prognostic model and risk calculator for the estimation of bipolar-spectrum disorder risk in hospitalised adolescents with non-psychotic/non-bipolar mental disorders 0.13
hiPSC-derived cortical neurons from ADHD individuals reveal dysregulated glutamatergic development 0.87
A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity 0.04
Hippocampal Cofilin and CFL1 gene variants are linked to Alcohol Use Disorder phenotypes 0.24
GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study 0.01
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth 0.36
Heavy adolescent drinking makes the adult brain more vulnerable to ethanol by permanently altering the age-dependent interplay between alcohol, GIRK channels and activin 1.00
Neurodevelopmentally rooted epicenters in schizophrenia: sensorimotor-association spatial axis of cortical thickness alterations 0.23
Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism 0.09
12 4.22
Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR 0.15
A spatial atlas of the healthy human liver from live donors 0.04
Albumin orchestrates a natural host defence mechanism against mucormycosis 0.02
Prevalence of Alzheimer’s disease pathology in the community 0.03
Sustained HIV-1 remission after heterozygous CCR5Δ32 stem cell transplantation 0.97
Rare genetic variants confer a high risk of ADHD and implicate neuronal biology 0.20
Spatial fibroblast niches define Crohn’s fistulae 0.03
Programmable antisense oligomers for phage functional genomics 1.00
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury 0.80
Feline infectious peritonitis epizootic caused by a recombinant coronavirus 0.06
The spatiotemporal distribution of human pathogens in ancient Eurasia 0.08
Kupffer cell programming by maternal obesity triggers fatty liver disease 0.85
1 0.83
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis 0.83
102 46.04
Impaired glucose tolerance and mild diabetes induce β-cell dysfunction in mice 0.05
Quantifying phage-host dynamics using droplet microfluidics 1.00
TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network 0.73
Predicting individual differences of fear and cognitive learning and extinction 0.94
Prolonged β2-agonist treatment enhances muscle-specific glucose uptake in individuals with overweight and obesity: a randomized placebo-controlled trial 0.08
Improved dynamic MRI of the wrist and heart at 0.55 T enabled by rapid 3D printed flexible coils 0.11
Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids 0.64
Indirect inhibition of the NLRP3-interleukin-1β axis contributes to the efficacy of JAK1 inhibitors in experimental colitis and human ulcerative colitis 0.79
Structural analyses uncover protease-adhesin interactions and c-di-GMP receptor regulation in sulfate-reducing bacteria 0.71
Wireless electrostimulation implants enable sphincter neuromuscular improvement toward mixed urinary incontinence 0.04
Temporal predictions shape somatosensory perception 1.00
An ancient genome of Streptococcus pyogenes from a pre-Columbian Bolivian mummy 0.10
Subcellular reorganization upon phage infection reveals stepwise assembly of viral particles from membrane-associated precursors 0.34
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.21
A bridge-like lipid transfer protein is critical for generation of invasive stages in malaria parasites 0.90
Sustained visceral fat loss is associated with attenuated brain atrophy and improved cognitive function in late midlife 0.20
Single-cell multi-omic analysis of mitochondrial mutational mosaicism and dynamics 0.93
Frazzled/DCC directs spatial progenitor integration ensuring steady-state intestinal turnover 0.75
Noradrenaline causes a spread of association in the hippocampal cognitive map 0.04
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication 0.50
A human cerebral organoid model of West Nile virus encephalitis shows innate immunocompetency 1.00
Subtypes of adolescent major depressive disorder characterized by divergent information dynamics in sensory-association cortices 0.05
Loss-of-function variants in the CAPN1 activator cause X-linked spastic ataxia 0.94
Latent transition analysis for longitudinal studies of post-acute infection syndromes 0.04
Opposite effects of chronic HIV infection and antiretroviral medication on organismal and organ-specific biological aging 0.12
A 7 T fMRI dataset of synthetic images for out-of-distribution modeling of vision 0.50
Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian 0.13
A microphysiological human mini-bladder reveals urine-urothelium interplay in tissue resilience and UPEC recurrence in urinary tract infections 0.07
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial 0.98
Using the linear references from the pangenome to discover missing autism variants 0.02
Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers 0.06
Endothelial cell responses in sepsis are attenuated by targeting truncated procalcitonin 0.77
High-entropy alloy Janus artificial enzymes for pH-gated sequential redox therapy of drug-resistant bacterial infection 0.08
The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion 0.02
Acute exercise rewires the proteomic landscape of human immune cells 0.95
Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease 0.03
Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors 0.73
Immunologic and biophysical features of the BNT162b2 JN.1 and KP.2 adapted COVID-19 vaccines 0.10
Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men 0.03
A niche-dependent redox rheostat regulates epithelial stem cell fate 0.05
Laser-assisted microbial culturomics 1.00
The NMDA receptor subunit GluN2D is a potential target for rapid antidepressant action 0.89
GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes 0.20
Single versus combination treatment in tinnitus: an international, multicentre, parallel-arm, superiority, randomised controlled trial 0.50
Adaptive stretching of representations across brain regions and deep learning model layers 0.13
Directed evolution of phages in biofilms enhances Pseudomonas aeruginosa control through improved lipopolysaccharide recognition 0.17
Controllability changes pain perception by increasing the precision of expectations 1.00
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction 0.72
Distinct autoreactive CD19 plasma cell subsets accumulate in lupus-prone mice 0.82
Plasma p-tau217 as a biomarker of Alzheimer’s disease pathology in individuals with Down syndrome 0.02
Proteome atlas for mechanistic discovery and risk prediction of diabetic retinopathy 0.02
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.01
scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome 0.96
DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms 0.56
The diagnostic potential of proteomics and machine learning in Lyme neuroborreliosis 0.05
Eosinophil CD48 interactions with Candida albicans Als6 is protective in vitro and in mouse systemic candidiasis 0.08
The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration 0.99
Apolipoprotein A-IV fibrils: structural diagnosis of mixed cardiac amyloidosis 0.30
Thalamic regulation of reinforcement learning strategies across prefrontal-striatal networks 0.11
Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling 0.98
Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites 0.05
Artery formation in the intestinal wall and mesentery by intestine-derived Esm1+ endothelial cells 0.89
SARS-CoV-2 infection dynamics in a MHCI-mismatched lung transplant recipient 0.97
Emergence of a carbapenem-resistant atypical uropathogenic clone as an increasing cause of urinary tract infection 0.06
All-optically controlled phased-array for ultrasonics 0.90
Trait anxiety is associated with reduced reward-related replay at rest 0.04
Neural correlates of human fear conditioning and sources of variability in 2199 individuals 0.39
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge 0.16
Early noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease 0.89
Exome analysis links kidney malformations to developmental disorders and reveals causal genes 0.00
Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model 0.34
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes 0.12
Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning 0.13
A single mutation may contribute to accelerated evolution of SARS-CoV-2 toward Omicron 0.23
Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics 0.49
A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis 0.12
Developing serum proteomics based prediction models of disease progression in ADPKD 1.00
Plasma proteomics for biomarker discovery in childhood tuberculosis 0.02
Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway 0.75
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge 0.08
Genetic risk-dependent brain markers of resilience to childhood Trauma 0.39
Suppression of gut colonization by multidrug-resistant clinical isolates through cooperative niche exclusion 1.00
Spatial and single cell mapping of castleman disease reveals key stromal cell types and cytokine pathways 0.03
The postbiotic ReFerm® versus standard nutritional support in advanced alcohol-related liver disease (GALA-POSTBIO): a randomized controlled phase 2 trial 0.24
Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants 0.50
Abstract rule learning promotes cognitive flexibility in complex environments across species 0.85
Obesity drives depot-specific vascular remodeling in male white adipose tissue 0.69
Confirmation bias through selective readout of information encoded in human parietal cortex 0.71
PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription 0.07
Prion-induced ferroptosis is facilitated by RAC3 0.53
Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62 1.00
Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype 1.00
Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa 0.75
An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis 0.05
Single-cell analyses identify monocyte gene expression profiles that influence HIV-1 reservoir size in acutely treated cohorts 0.06
Modelling POLG mutations in mice unravels a critical role of POLγΒ in regulating phenotypic severity 0.05
Adjunctive phage therapy improves antibiotic treatment of ventilator-associated-pneumonia with Pseudomonas aeruginosa 0.80
Label-free multimodal optical biopsy reveals biomolecular and morphological features of diabetic kidney tissue in 2D and 3D 0.14
Microvascular immunity is organ-specific and remodeled after kidney injury in mice 1.00
HiBC: a publicly available collection of bacterial strains isolated from the human gut 0.92
Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration 0.82
Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes 0.60
4 0.42
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling 0.20
Proteome-wide model for human disease genetics 0.10
Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression 0.02
Genome-wide association study of long COVID 0.11
2 0.41
Quantifying the impact of hair and skin characteristics on fNIRS signal quality for enhanced inclusivity 0.02
Representational dynamics during extinction of fear memories in the human brain 0.39
9 4.18
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size 0.02
Autologous neutralizing antibodies and polyfunctional T cells contribute to long-term HIV-1 post-intervention control 0.10
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses 0.01
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332 glycan-independent epitope 0.41
Skin-derived myeloid precursors and joint-resident fibroblasts spread psoriatic disease from skin to joints 0.68
Enteric nervous system-derived VIP restrains differentiation of LGR5 stem cells toward the secretory lineage impeding type 2 immune programs 0.76
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy 0.37
Spatiotemporal interaction of immune and renal cells controls glomerular crescent formation in autoimmune kidney disease 1.00
The IL-22–oncostatin M axis promotes intestinal inflammation and tumorigenesis 0.85
15 3.44
Semaglutide on liver fibrosis and heart outcomes in patients at high risk of liver fibrosis: a prespecified analysis of the SELECT randomized trial 0.02
Deleterious coding variation associated with autism is shared across ancestries 0.01
Blood phosphorylated tau elevation as a biomarker in immunoglobulin light chain and transthyretin amyloidosis 0.63
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.01
External trigeminal nerve stimulation in youth with ADHD: a randomized, sham-controlled, phase 2b trial 0.06
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure 0.09
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial 0.01
Varicella-zoster virus reactivation and the risk of dementia 0.15
Sonelokimab, an IL-17A/IL-17F-inhibiting nanobody for active psoriatic arthritis: a randomized, placebo-controlled phase 2 trial 0.10
Full-spectrum extract from DKJ127 for chronic low back pain: a phase 3 randomized placebo-controlled trial 0.83
Prevention of type 2 diabetes through prediabetes remission without weight loss 0.85
Early-life serological profiles and the development of natural protective humoral immunity to in a high-burden setting 0.01
Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial 0.08
T and B cell responses against Epstein–Barr virus in primary sclerosing cholangitis 0.59
An international Delphi consensus for reporting of setting in psychedelic clinical trials 0.01
1 0.18
HippoMaps: multiscale cartography of human hippocampal organization 0.18
3 0.26
A neural signature of adaptive mentalization 0.13
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time 0.11
A common computational and neural anomaly across mouse models of autism 0.02
1 0.13
Structure and mechanism of antiphage retron Eco2 0.13
3 0.94
Representational similarity modulates neural and behavioral signatures of novelty 0.17
Structure in noise: Recurrent connectivity shapes neural variability to balance perceptual and cognitive demands in the human brain 0.67
Spontaneous movements and their relationship to neural activity fluctuate with latent engagement states 0.11
9 3.89
Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions 0.02
Aberrant dopaminergic activity during consolidation causes age-related memory generalization in Drosophila 0.18
Prenatal and early postnatal periods differentially shape the maturation of human cortical microstructure and myelin 0.80
Cardiometabolic health and physical robustness map onto distinct patterns of brain structure and neurotransmitter systems 0.70
Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors 0.04
Plasma membrane recycling drives reservoir formation during Toxoplasma gondii intracellular replication 0.83
Catecholamines reduce choice history biases in perceptual decision making. 0.83
Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply. 0.11
Neural evidence that humans reuse strategies to solve new tasks 0.38
4 0.28
Effect of enhanced peer PrEP referral with HIV self-testing delivery among young Kenyan women: A randomized controlled trial of peer networks 0.03
Hospital-based care for hallucinogens and risk of mania and bipolar disorder: A population-based cohort study 0.04
Diagnostic accuracy of the WHO tuberculosis treatment decision algorithms for children with presumptive tuberculosis: An individual participant data meta-analysis 0.14
Predicting knee osteoarthritis progression using neural network with longitudinal MRI radiomics, and biochemical biomarkers: A modeling study 0.07
1 0.92
Phage Display Derived Antibodies Against Antimicrobial Peptide FsPDF2 Reveal Stress Response in European Beech 0.92
19 9.44
Dopamine D1 and D2 receptors differentially control strength and dynamics of abstract decision codes in the primate prefrontal cortex 1.00
Memory B cell development in response to mRNA SARS-CoV-2 and nanoparticle immunization in mice 0.04
Conjunctive population coding integrates sensory evidence to guide adaptive behavior 0.43
Physical exercise increases binding of POMC to blood extracellular vesicles 0.14
The olfactory bulb endocast as a proxy for mammalian olfaction 0.60
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination 0.13
Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease 0.89
Synergistic interactions between Candida albicans and Enterococcus faecalis promote toxin-dependent host cell damage 0.79
Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study 0.87
Micro-offline gains do not reflect offline learning during early motor skill acquisition in humans 0.80
Learning expectations shape cognitive control allocation 0.17
Specificities of chemosensory receptors in the human gut microbiota 0.67
Flavin-deficient erythrocytes offer protection against malaria parasites 0.27
Replay in the human visual cortex during brief task pauses is linked to implicit learning of successor representations 1.00
Cell type–specific purifying selection of synonymous mitochondrial DNA variation 0.39
<atl>Repurposing a drug to punish carbapenem-resistant iAcinetobacter baumannii/i</atl> 0.18
Protein kinase A signaling regulates immune evasion by shaving and concealing fungal β-1,3-glucan 0.04
Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses 0.93
Next-generation rifamycins for the treatment of mycobacterial infections 0.10
2 1.18
Humans choose trunk lean angles consistent with minimal metabolic costs—an integrative experimental and musculoskeletal simulation approach 0.58
Postural stability and optic flow sensitivity following sight restoration from congenital bilateral cataracts. 0.60
6 2.15
Effect of Reporting Mode and Clinical Experience on Radiologists' Gaze and Image Analysis Behavior at Chest Radiography. 1.00
Middle Meningeal Artery Embolization for Subdural Hematoma: CT/MRI End Points of the EMBOLISE Trial. 0.23
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI. 0.17
Deep Learning-based Opportunistic CT Osteoporosis Screening and the Establishment of Normative Values. 0.40
Prognostic Value of Global Longitudinal Strain using Automated Measurement in Cardiac MRI. 0.06
Noninvasive Tumor Profiling: Quantitative Contrast-Enhanced MRI Markers Predict PD-L1 and CTNNB1 Status in Hepatocellular Carcinoma. 0.30
4 1.16
Distinctive DNA sequence features define epigenetic longevity of inflammatory memory 0.27
Estrogen-regulated renal progenitors determine pregnancy adaptation and preeclampsia 0.10
Mitochondria protect against an intracellular pathogen by restricting access to folate 0.62
A metabolite-based resistance mechanism against malaria 0.18
14 5.85
Type 2 lymphocytes restrict type 3 lymphocytes during liver fibrosis and colocalize in fibroblast niches 0.15
Whole-brain meso-vein imaging in living humans using fast 7-T MRI 0.32
Integrin inhibition facilitates fibrocartilaginous transformation in connective tissue in osteoarthritis 0.05
Mechanistic insights into 50S precursor recognition and targeting by erythromycin resistance methyltransferase 0.18
Substitution of human olfaction by the trigeminal system 0.17
Mapping neurophysiological and molecular profiles of heterogeneity and homogeneity in schizophrenia-bipolar disorder 0.23
Immunopeptidome analysis reveals SERPINB3 as an autoantigen driving eczematized psoriasis 0.89
In vivo expression of VCAM1 precedes nephron loss following kidney tubular necrosis 0.04
The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice 0.03
Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection 0.81
Chemically induced deceleration of nuclear spin relaxation (CIDER) preserves hyperpolarization 1.00
HIV-1 manipulates CD96 on CD4+ T cells to subvert antiviral immunity 1.00
Heparan sulfate fine-tuned interleukin-1 (IL-1) signaling inhibits insulin secretion of grafted pancreatic islets 0.93
Staphylococcus aureus LukMF′ targets neutrophils to promote skin and soft tissue infection 0.06
4 2.81
Metabolic acidosis causes a Fanconi-like syndrome with intracellular trafficking defects and proximal tubule dysfunction 0.77
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis 0.07
Low-dose glucocorticoids attenuate crescentic glomerulonephritis by inhibiting the local differentiation of proinflammatory neutrophils 0.97
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion 1.00
4 1.06
Effects of lifestyle interventions in pregnancy on gestational diabetes: individual participant data and network meta-analysis 0.02
Benefits and harms of ADHD interventions: umbrella review and platform for shared decision making 0.02
Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis 0.08
Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial 0.94
5 4.01
Lenacapavir-induced capsid damage uncovers HIV-1 genomes emanating from nuclear speckles 1.00
RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis. 0.26
Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection. 0.87
Morphology-dependent entry kinetics and spread of influenza A virus 0.98
Aldolase-regulated G3BP1/2+ condensates control insulin mRNA storage in beta cells 0.90
4 2.81
Sulfoquinovose degradation by cow rumen microbiota 0.11
DNA virus–host patterns in lake and marine environments over the last glacial cycle 1.00
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition 1.00
Function-based selection of synthetic communities enables mechanistic microbiome studies 0.70
12 2.99
ADAM8 mediates eosinophil and neutrophil infiltration and tissue remodeling in chronic rhinosinusitis with nasal polyps 0.09
IL-2 synergizes with proinflammatory type 3 inducers to amplify mixed type 2–type 3 inflammation in nasal polyps 0.09
Staphylococcal superantigen–specific IgE reveals functional superantigen production beyond Staphylococcus aureus in CRSwNP 0.12
Inhibition of RIPK1 prevents keratinocyte cell death and reduces skin inflammation in type 1–mediated chronic inflammatory skin diseases 1.00
Bimekizumab long-term response in psoriasis: Mechanistic insights into efficacy level and durability 0.06
Epinephrine and Emergency Medical Services Activation Recommendations During Acute Allergic Reactions in Community Settings: International Consensus Report 0.02
Targeting IL-22RA1 with Temtokibart: A Novel Approach in Atopic Dermatitis: Phase 2a Monotherapy Study Results 0.15
Remibrutinib in chronic spontaneous urticaria: 52-Week results from two phase 3 studies 0.05
S-Ruxolitinib: a novel JAK/STAT-targeted therapy through restoring mucosal homeostasis for chronic rhinosinusitis with nasal polyps 0.09
Collagen XXIII (COL23A1): A novel risk factor for eczema herpeticum 1.00
Inhibition of lysosomal degradation increases expression of mutant ADA2 in DADA2 monocytes 0.15
Dissecting key contributions of Th2 and Th17 cytokines to atopic dermatitis pathophysiology 0.18
1 0.08
Nanoclay-Interface-Mediating Charge Redistribution for Effective Wound Healing 0.08
5 1.00
TRPC6 inhibition for the treatment of focal segmental glomerulosclerosis: a randomised, placebo-controlled, phase 2 trial of BI 764198 0.24
Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study 0.03
A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial 0.43
Once-daily oral icotrokinra versus placebo and once-daily oral deucravacitinib in participants with moderate-to-severe plaque psoriasis (ICONIC-ADVANCE 1 & 2): two phase 3, randomised, placebo-controlled and active-comparator-controlled trials 0.20
Once-weekly insulin efsitora alfa versus once-daily insulin glargine U100 in adults with type 2 diabetes treated with basal and prandial insulin (QWINT-4): a phase 3, randomised, non-inferiority trial 0.11
3 0.41
Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study 0.18
Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study 0.10
Surgery for the treatment of arterial hypertension in patients with unilateral adrenal incidentalomas and mild autonomous cortisol secretion (CHIRACIC): a multicentre, open-label, superiority randomised controlled trial 0.13
5 0.63
HIV testing during systematic screening for tuberculosis among household contacts in high-tuberculosis burden settings: a systematic review and meta-analysis 0.03
The aetiology and prevalence of preoperative anaemia in patients undergoing major surgery (ALICE): an international, prospective, observational cohort study 0.21
Melioidosis in Mali: a retrospective observational study 0.14
Causes, associated exposures, and outcomes of cirrhosis and hepatocellular carcinoma in Malawi: an observational cohort and case–control study 0.20
Global variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study 0.05
5 0.40
First-episode psychosis and substance use involvement across birth cohorts in Canada: a retrospective longitudinal population-based study 0.04
Joint detection of risk for psychotic disorders or bipolar disorders in clinical practice in the UK: development and validation of a clinical prediction model 0.02
Efficacy and safety of iclepertin for cognitive impairment associated with schizophrenia (CONNEX programme): results from three phase 3 randomised controlled trials 0.23
Transdiagnostic effectiveness and safety of clozapine in individuals with psychotic, affective, and personality disorders: nationwide and meta-analytic comparisons with other antipsychotics 0.04
Real-world effectiveness of clozapine augmentation with antidepressants: within-subject data evidence from two European nationwide cohorts 0.07
12 1.42
Pulmonary Tuberculosis Detection with MiniDock MTB Using Swab Samples 0.13
Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI 0.14
Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism 0.20
Finerenone in Type 1 Diabetes and Chronic Kidney Disease 0.26
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes 0.07
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy 0.05
Oral Icotrokinra for Plaque Psoriasis in Adults and Adolescents 0.06
Belzutifan for Advanced Pheochromocytoma or Paraganglioma 0.08
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity 0.09
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 0.20
Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma 0.04
Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis 0.09
1 1.00
Action spectrum of Bacillus subtilis spores for validation of polychromatic ultraviolet (UV) systems 1.00

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