Clinical Sciences articles for Japan

Time frame: 1 May 2025 - 30 April 2026

View topic

Count: 309

Article ‘Count’ for Clinical Sciences.

Journal Count Share
1 0.10
Evaluation of Malaria Parasite Transmission Competency Using a Nanozyme-Based Immunodiagnostic Targeting Female Gamete Antigen Release 0.10
1 1.00
Genetic predisposition for immunoglobulin E production explains atopic risk in children: Tohoku Medical Megabank cohort study 1.00
2 2.00
Iron and bile acids synergize to exacerbate congenital cholestatic liver injury via ferroptosis 1.00
Low-potassium triggers tubular epithelial NLRP3/ASC-driven kidney inflammation independently of inflammasomes 1.00
4 2.88
Early Changes of Lung Mechanics After PEEP Reduction in ARDS: A 4D-CT Study 0.86
Lung stress mapping: an innovative technology to visualize the hidden risk of ventilator-induced lung injury 1.00
Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study 0.02
Transcriptomic Profiling in Mycobacterium avium Complex Pulmonary Disease Identifies Clusters Linked to Disease Severity and Neutrophil Activation. 1.00
2 1.86
Antimicrobial Peptide Activity in Lipid Bilayers with Smooth-Type Lipopolysaccharides 1.00
Seamless Tiling and Scalable Coherent Raman Spectroscopic Analysis Reveals Developmental Maturation of Lipids in the Mouse Brain 0.86
2 2.00
Adverse events associated with airway management in pediatric anesthesia: A prospective, multicenter, observational Japan Pediatric Difficult Airway in Anesthesia (J-PEDIA) study. 1.00
Synergistic effects of commonly used ICU drugs and high temperature on skeletal muscle at the cellular and tissue levels. 1.00
2 1.77
Aggregation‐State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL‐37 and HNP1 0.85
A Photoresponsive Hybrid of Viruses and Supramolecular Peptide Fibers for Multidimensional Control of Patterning and Infection 0.92
1 0.04
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis. 0.04
1 0.04
Longitudinal Phenotypic Trajectories in GNAO1-Related Disorders: Defining Disease Progression and Clinical Profiles 0.04
6 2.34
Prognostic Impact of Postoperative Complications After Neoadjuvant Therapy Followed by Esophagectomy for Esophageal Cancer: An Exploratory Analysis of Phase III Trial JCOG1109. 1.00
Two-stage Hepatectomy Versus Liver Transplantation for Patients with Marginally Resectable Extensive Bilobar Colorectal Liver Metastases. 0.18
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.10
MiR-7-5p as a Diagnostic and Monitoring Biomarker for Neuroendocrine Tumors: Insights from the SKY-NET Multicenter Study. 1.00
Novel Benchmark for Robotic Liver Resection - Bridging Tradition with Innovation. 0.03
Abnormal Milan Score and Compromised Esophageal Mucosal Integrity Stratify Gastroesophageal Reflux Disease Severity. 0.04
5 2.15
Risk score for early mortality to stratify for intensive SSc therapy in the EUSTAR network: the RESIST score 0.05
Quantitative MRI tenosynovitis volume explains the association between tendon involvement and future development of clinical arthritis in anti-cyclic citrullinated peptide-positive at-risk individuals 0.06
Spacing of a TNF inhibitor or dose reduction of methotrexate vs continued treatment in patients with rheumatoid arthritis in remission or low disease activity: a randomised, controlled trial (SORAIRO trial) 1.00
Integrative spatial multiomics analysis reveals regulatory mechanisms of VCAM1+ proximal tubule cells in lupus nephritis 0.05
Osteoarthritis risk associated with romosozumab compared with teriparatide in individuals with osteoporosis: a target trial emulation study 1.00
1 1.00
Spatial sound modulation through manual reconfiguration of phased plate 1.00
5 5.00
Integrated Structural Analysis of Trunk Function Assessment After Stroke—New Evaluation Model Based on Multiscale Factor Analysis and Rasch Analysis 1.00
Association Between Mobility as a Time-Dependent Exposure Factor and Risk of Fall: A Retrospective Cohort Study of Older Patients with Orthopedic Conditions in a Sub-acute Rehabilitation Setting 1.00
Does the Minimal Detectable Change in the 10-Meter Walk Test and Timed Up and Go Test Differ by Parkinson’s Disease Severity? 1.00
The dose-response relationship between gait training dose and gait independence in individuals with hemiparetic stroke 1.00
Association between weekly amount of home-visit rehabilitation and changes in activities of daily living: A retrospective cohort study using home-visit nursing station records 1.00
11 5.18
Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA-Reporter Assay 1.00
Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study 1.00
Baseline Interleukin‐10 Levels as a Predictive Biomarker for Achieving Clinical Response With Abatacept in Patients Who Were Disease‐Modifying Antirheumatic Drug Naive and Anti–Citrullinated Protein Antibody Positive With Early Rheumatoid Arthritis 0.07
Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus 1.00
Relapse Rate After Glucocorticoid‐free Remission in patients with Idiopathic Inflammatory Myopathies and Validation of the International Myositis Assessment and Clinical Studies Group (IMACS) Criteria for Complete Clinical Response and Worsening 0.08
Toward a treat‐to‐target strategy in juvenile dermatomyositis: what are the suitable targets and optimal timing of their achievement? 0.05
Longitudinal Changes in Serum Urate Levels from Pre‐menopause through Post‐menopause: Interrupted Time‐Series Analyses 0.55
Efficacy and Safety of ABBV-154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo-Controlled Trial 0.07
ADAM9 promotes glycolysis in Th17 cells and autoimmunity through activation of IGF‐1 signaling 0.21
Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China 0.15
HLA class I‐downregulated senescent epidermal basal cells orchestrate skin pathology in cutaneous lupus erythematosus 1.00
2 1.18
Transthyretin variants impact blood–nerve barrier and neuroinflammation in amyloidotic neuropathy 0.18
Oligoadenylate synthetase 1a suppresses prion infection through binding to cellular prion protein 1.00
1 0.12
Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression 0.12
1 0.03
FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression 0.03
1 1.00
Niche-preserving transplantation promotes functional engraftment of intestinal organoids in rat short bowel syndrome 1.00
2 0.16
TRPM7 Deficiency Protects Against Myocardial Ischemia-Reperfusion Injury by Regulating Intracellular Zn2+ Homeostasis. 0.09
Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: a Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial. 0.07
2 1.06
Randomized Pragmatic Trial of the Comparative Effectiveness of Chicken Egg-Based Inactivated, Mammalian Cell Culture-Based Inactivated, and Recombinant Protein Quadrivalent Seasonal Influenza Vaccines in United States Military Health System Beneficiaries 0.06
Contamination of Blood Cultures Drawn From Arterial Catheters Versus Venipuncture or Venous Catheters in Critically Ill Patients: A Systematic Review and Meta-analysis 1.00
1 1.00
Temporal dynamics in the content of wishes after the expression of suicidal ideation on Twitter: Focusing on changes in retweet content 1.00
13 11.66
Temporal Trends in Outcomes After Out-of-Hospital Cardiac Arrest Transported to Critical Care Medical Centers in Japan, 2014-2022: A Nationwide Retrospective Observational Study. 1.00
Association Between Systemic Anticoagulation and Outcomes in Patients With Acute Respiratory Distress Syndrome Receiving Venovenous Extracorporeal Membrane Oxygenation: Insights From a Multicenter Propensity-Weighted Study. 1.00
Gender Disparity in Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest. 0.69
Recombinant Human Soluble Thrombomodulin and In-Hospital Mortality in Acute Pancreatitis With Disseminated Intravascular Coagulation: A Japanese Nationwide Study. 0.92
Risk of Developing Lower Limb Ischemia in Patients With Extracorporeal Cardiopulmonary Resuscitation: A Secondary Analysis of the Study of Advanced Cardiac Life Support for Ventricular Fibrillation With Extracorporeal Circulation in Japan II (SAVE-J II) Study. 1.00
Acute Kidney Injury After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest. 1.00
Association Between Activation of a Rapid Response Team and Outcomes of Sepsis in General Wards: A Nationwide Observational Study Using the Japanese Intensive Care Patient Database. 1.00
Differentiating Lung From Chest Wall Mechanics Is Difficult Without Esophageal Manometry in Children With Acute Respiratory Distress Syndrome. 0.20
Association Between Patients' Admission to the ICU and Psychological Disorders in Their Families: A Retrospective Matched-Pair Cohort Study. 1.00
Association of Medical Burden and Capacity Changes With Clinical Outcomes Among Patients Without COVID-19 During the Pandemic: A Multicenter Retrospective Cohort Study. 1.00
The Impact of Hospital-Level Median Door-to-Extracorporeal Cardiopulmonary Resuscitation Time on the Prognosis of Patients With Refractory Out-of-Hospital Cardiac Arrest. 0.86
Comparison of the Incidence of Arterial Pressure Line Insufficiency Between Polyethylene and Polyurethane Catheters in the ICU: A Randomized Study. 1.00
Association Between Rewarming Rate and Survival and Neurologic Outcome of Accidental Hypothermia. 1.00
4 2.58
Motivation under aversive conditions is regulated by a striatopallidal pathway in primates 1.00
Monkeys adjust goals and strategies in a foraging task based on time constraints 1.00
Conscious awareness determines whether a second learning session disrupts or facilitates earlier learning 0.33
Excitatory drive to the globus pallidus external segment facilitates action initiation in non-human primates 0.25
2 1.07
Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial). 0.07
Prediction of Sarcopenia Onset in Type 2 Diabetes Using Urinary Titin Levels: A Japanese Prospective Cohort Study. 1.00
1 1.00
Effects of Bisphenol A and Retinoic Acid Exposure on Neuron and Brain Formation: a Study in Human Induced Pluripotent Stem Cells and Zebrafish Embryos. 1.00
3 1.06
Associations of prenatal exposure to organophosphate pesticides with eczema and allergic rhinoconjunctivitis in 4-year-old children: The Japan Environment and Children's Study 1.00
Prenatal exposure to persistent organic pollutants and sex-specific neonatal outcomes in the ENVIRONAGE birth cohort 0.03
Chemical exposure in childhood: A study on organophosphate flame retardants and plasticizers in a Flemish birth cohort 0.03
4 0.26
Silent plaque ruptures in non-obstructive lesions of non–infarct-related arteries: a multimodality, serial intracoronary imaging study 0.13
C-reactive protein and cardiovascular risk in the general population 0.04
Fractional flow reserve-guided renal artery stenting in atherosclerotic renovascular hypertension: the FAIR randomized trial 0.04
Cardiac amyloidosis detection from a single echocardiographic video clip: a novel artificial intelligence-based screening tool 0.04
1 0.00
RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery 0.00
5 1.17
Novel insights into autoimmune gastritis: clinical profile and gastric neoplastic risk from an international multicentre study 0.02
Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes 0.04
Autophagy of Kupffer cells modulates CD8+ T cell activation in primary biliary cholangitis 0.06
Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease 0.05
Prophylactic clip closure after endoscopic submucosal dissection of large flat and sessile colorectal polyps: a multicentre randomised controlled trial (EPOC trial) 1.00
4 0.16
Head-to-head comparison between vibration-controlled transient elastography and histology in predicting liver-related events due to metabolic dysfunction-associated steatotic liver disease. 0.05
Predictors of fibrosis, clinical events and mortality in MASLD: Data from the Global-MASLD study. 0.03
Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study. 0.03
Association between longitudinal weight change and clinical outcome in individuals with MASLD. 0.05
1 0.15
Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity 0.15
1 0.13
Concerted Reactive Adsorption and Photocatalytic Degradation of Bisphenol-S on Molybdenum Cluster-Modified Nanoceria 0.13
1 1.00
Relationship between shingles and coronavirus disease 2019: a self-controlled case series study 1.00
2 1.96
Clinical characteristics and survival in sarcopenic obesity defined by the Japanese working group on sarcopenic obesity criteria versus existing definitions in older adults: findings from the Otassha study 1.00
The impact of slope-adjusted visit-to-visit body mass index variability on early dementia risk prediction 0.96
1 0.29
Oral Semaglutide in an East Asian Population With Overweight or Obesity, With or Without Type 2 Diabetes 0.29
1 0.11
Differential Associations of Dopamine and Serotonin With Reward and Punishment Processes in Humans 0.11
1 0.44
Diagnostic Accuracy of Imaging in Assessing Nonviability of Disappearing Colorectal Liver Metastasis 0.44
3 1.11
Discordance in Creatinine- and Cystatin C–Based eGFR and Clinical Outcomes 0.07
Rituximab for Relapsing Nephrotic Syndrome in Adults 1.00
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.04
7 5.93
Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and composition 1.00
Structural basis for heme binding by the Shr protein from Streptococcus pyogenes. 1.00
Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis 0.04
Adductome-based identification of lysine monomethylation as a key post-translational protein modification in autoimmune diseases 1.00
ZFP36L1 and L2 as novel antiviral factors for Crimean-Congo hemorrhagic fever virus via interaction with viral nucleoprotein 1.00
Induction of the zinc finger transcription factor GATA2 promotes kidney inflammation-related gene expression 1.00
Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice 0.90
8 6.47
Radiographic Measurement of Psoas Muscle Width: A Simple and Reliable Screening Tool for Sarcopenia. 1.00
Transthyretin Amyloid May Drive Fibrosis and Proliferation of Tenosynovial Fibroblasts in Carpal Tunnel Syndrome. 1.00
Compensatory Load Sharing by Residual Rotator Cuff Subregions Preserves Glenohumeral Mechanics in Partial and Massive Tears. 0.38
The Trapezius Aponeurosis Insertion on the Acromion: An Anatomical Study with a Possible Implication for Dynamic Stabilization of the Acromioclavicular Joint. 1.00
Diagnostic Utility of a Rapid Myeloperoxidase Test in Synovial Fluid for Chronic Periprosthetic Joint Infection 1.00
Normalization of Subchondral Bone Density Patterns After Surgical Treatment for Capitellar Osteochondritis Dissecans: A Quantitative Analysis. 1.00
Minimized Medial Soft Tissue Release with Bone-Recut Adjustment Improves Short-Term Outcomes: Compared with Medial Release in Posterior-Stabilized Total Knee Arthroplasty. 1.00
The T4-L1-Hip Axis Objectifies the Roussouly Classification Using Continuous Measures. 0.09
1 0.10
Natural bio-photosensitizers in sludge: Extracellular polymeric substances (EPS)-driven persulfate activation for sustainable antibiotic degradation 0.10
17 15.31
Real-world impact of treatment on growth in children with X-linked hypophosphatemia 0.31
Partial pressure of oxygen-guided adrenal venous sampling in primary aldosteronism 1.00
Automatic acromegaly detection using deep learning on hand images: a multicenter observational study 1.00
Magnesium sulfate may unmask subclinical excess vasopressinase-induced arginine vasopressin disorder 1.00
Inflammatory Markers Link Steroid Profiles to Bone Status in Patients with Autonomous Cortisol Secretion 1.00
Comprehensive Molecular Studies in 88 Japanese Patients With Congenital Hypogonadotropic Hypogonadism 1.00
Enhancing Accuracy of Newborn Screening for 21OHD: Strategic Use of 21-Deoxycortisol in a Large-Scale Tokyo Cohort 1.00
Trends In Reported Outcomes for Growth Hormone Therapy In Children With Growth Hormone Deficiency 0.05
Genetic and Clinical Characteristics of Monogenic Diabetes in Japan: A Nationwide Study by the Japan Diabetes Society 0.96
Impact of minimal dose strategy before anti-thyroid drug discontinuation on relapse risk in Graves’ disease 1.00
The time of the hypertonic saline infusion test for the diagnosis of AVP deficiency can be shortened with LC-MS/MS 1.00
The Significance of High Expression of Circulating miR-222-3p in Patients With Unilateral Primary Aldosteronism 1.00
PHEX Protein in the Parathyroid Gland Contributes to Phosphate Sensing 1.00
Multiple or Single Endocrine Abnormalities Associated With Immune Checkpoint Inhibitors 1.00
Clinical and Genetic Characteristics of Adult Nonautoimmune Hypothyroidism: A Single-Institution Study 1.00
Coproporphyrinogen oxidase deficiency causes primary adrenal insufficiency and 46,XY DSD 1.00
CCNA2 and CCND2 are differentially involved in β-cell proliferation in perinatal Japanese autopsied subjects 1.00
3 0.71
Postnatal Slc26a4 gene therapy improves hearing and structural integrity in a hereditary hearing loss model 0.25
Intermittent ischemia/reperfusion as a potent insulin-sensitizing intervention via blood flow enhancement and muscle decanoyl-l-carnitine suppression 0.21
Histamine H1 receptor inverse agonists improve structure and pain in an osteoarthritis mouse model 0.25
4 0.87
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials 0.04
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.02
Reversal of ACLF and ALF using whole blood extracorporeal system combining HLA-depleted liver organoids with granulocyte-monocyte apheresis 0.76
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.06
4 2.97
Tracking Plasmodium knowlesi Through Fecal DNA for Monitoring Zoonotic Transmission in Wild Macaques Across Southeast and South Asia 0.31
Epidemiological, clinical, and virological characterizations of Yezo virus infections, an emerging tick-borne orthonairovirus disease in Japan 1.00
Prevalence of Candidate Vaccine Targets and Genomic Features of Pediatric Invasive Streptococcus Agalactiae in Japan 1.00
iStreptococcus pyogenes/i Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock Syndrome in Rural Japan 0.66
8 5.33
Dopamine Dynamics in the Nucleus Accumbens Reflect Confidence in Detecting the Occurrence and Non-Occurrence of Visual Signals in Perceptual Decision-Making 0.11
Mesocorticostriatal reinforcement learning of state representation and value with implications for the mechanisms of schizophrenia 0.50
Local neuronal ensembles that co-reactivate across regions during sleep are preferentially stabilized 1.00
Functional near-infrared spectroscopy reveals functional rewiring between macaque motor areas following post-infarction recovery of manual dexterity 1.00
Behavioral relevance of early neural coding of low-level odor features in humans 1.00
Differential and temporally dynamic involvement of primate amygdala nuclei in face reality and reward information processing 1.00
Striatal Gradient in Value-Decay Explains Regional Differences in Dopamine Patterns and Reinforcement Learning Computations 0.50
Structural Regeneration and Functional Recovery of the Olfactory System of Adult Zebrafish Following Brain Injury 0.22
3 3.00
Intramuscular neutrophil‐derived immunometabolic niches locally boost insulin‐responsive GLUT4 translocation after muscle contraction 1.00
A novel stromal cell source of RANKL during sustained osteoclast activation in disuse osteoporosis 1.00
Cross‐modal predictive oculomotor control: visually acquired prediction transfers to vestibular‐driven eye movements 1.00
6 5.85
The harvesting technique affects the production of nitric oxide and endothelin in the internal thoracic artery graft 1.00
Short-term outcomes of thrombolysis versus surgical pulmonary embolectomy in patients with high-risk pulmonary embolism 1.00
Long-term clinical outcomes and morphology of no-touch saphenous vein grafts 1.00
Optimal size matching leads to a favorable outcome for single-lobe living-donor lung transplantation 1.00
Combined inflation and cooling method improves lung function in uncontrolled donation after circulatory death 0.85
Outcomes of adult-to-adult living-donor lobar lung transplantation: A single institution experience 1.00
1 0.06
Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension 0.06
1 1.00
Expanding the Chemical Space of Antimicrobial Peptides via Enzymatic Prenylation 1.00
2 1.04
Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of CONFIDENCE Randomized Trial 0.07
Frailty Scale Captures Multidimensional Vulnerability and Predicts Mortality in Heart Failure 0.97
5 4.29
Association Between Frailty and Patients' Experience of Cancer Treatment and Care 0.75
Cataract Surgery Under General Anesthesia in Older Adults With Advanced Cataracts and Dementia: Visual Acuity and Visual Function Outcomes 1.00
scpSGLT2/scp Inhibitors in Older Adults With Cardiovascular Disease: A Systematic Review and Meta‐Analysis 0.54
Clinical and Prognostic Utility of the Essential Frailty Toolset in Older Patients With Heart Failure 1.00
Prevalence and Prognostic Implication of Sarcopenia Among Patients With Stage B Heart Failure: The PAPRIKA-HF Cohort Study 1.00
6 3.82
Structural Plasticity of Aged Podocytes Revealed by Volume Electron Microscopy 1.00
Pyruvate Dehydrogenase and Cellular Metabolism in Calcineurin Inhibitor-Induced Kidney Fibrosis. 0.71
Differential Cell-Specific, Regulatory Roles of FcγRIIB through IgG in IgA Nephropathy. 0.03
Cardiac LIM Protein, Kidney Fibrosis, and Vascular Change after Acute Cardiorenal Syndrome. 0.07
Cdc42 Activation in Anti-nephrin Antibody-Induced Nephropathy. 1.00
Voclosporin Overdose-Induced Peroxisomal Structural Changes and AKI Are Prevented by Renal Indole Detoxifier, INMT. 1.00
2 0.96
Roles of WNK1 and mTORC2 in aldosterone-independent regulation of potassium secretion in the distal nephron. 0.14
Syntaxin 3 regulates apical membrane integrity in proximal tubule epithelial cells and prevents Fanconi syndrome development 0.81
12 7.21
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.09
Antipsychotic-like effects of the selective Rho-kinase 2 inhibitor KD025 in genetic and pharmacological mouse models of schizophrenia 1.00
NADPH oxidase-1 suppression prolongs the antidepressant-like effect of ketamine 0.94
The dynamics of AMPA receptors underlies the efficacy of ketamine in treatment resistant patients with depression 0.98
Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide 0.01
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.05
Generalizable stratification based on thalamo–somatomotor functional connectivity predicts responses to antidepressants in patients with depression 1.00
Interrelations between dopaminergic-, gabaergic- and glutamatergic neurotransmitters in antipsychotic-naïve psychosis patients and the association to initial treatment response 0.09
Rapid and long-lasting antidepressant-like effects of the pituitary adenylate cyclase-activating polypeptide receptor antagonist PA-915 in chronic stress mouse models 1.00
Effects of esketamine on electrophysiology and metabolic reprogramming in brain organoids: insights into antidepressant mechanisms 0.05
Brain structure characteristics in children with attention-deficit/hyperactivity disorder elucidated using traveling-subject harmonization 1.00
Single-molecule DNA analysis implicates brain mitochondria pathology in bipolar disorder 1.00
4 2.02
B cell imprinting in children impairs antibodies to the haemagglutinin stalk 0.02
The astrocytic ensemble acts as a multiday trace to stabilize memory 0.98
mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity 0.02
Microbiota-driven antitumour immunity mediated by dendritic cell migration 1.00
38 23.51
The role of Pth1r in posterior cranium cartilage regulation and craniosynostosis 1.00
Phage homing endonuclease amplifies anti-defense genes to evade bacterial immunity 0.67
Aberrant laminin signaling drives melanocyte dedifferentiation and unveils a tractable therapeutic target in vitiligo 1.00
Fc-free single-chain antibody mRNA therapy for airway infection of multidrug-resistant Pseudomonas aeruginosa 1.00
An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells 0.78
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.08
Role of the primate ventral striatum as a neural hub bridging option valuation and action selection 1.00
A genetic toolkit for the human gut bacterium Mediterraneibacter gnavus identifies capsular polysaccharides as a competitive colonization factor 1.00
Excess FGFR3 signaling in achondroplasia disrupts turnover of resting zone chondrocytes via CREB signaling 1.00
Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian 0.13
Using the linear references from the pangenome to discover missing autism variants 0.01
An H5N1 clade 2.3.4.4b virus vaccine that elicits cross-protective antibodies against conserved domains of H5 and N1 glycoproteins 0.05
Disturbances of paraventricular thalamic nucleus neurons in bipolar disorder revealed by single-nucleus analysis 0.80
Spatially heterogeneous acetylcholine dynamics in the striatum promote behavioral flexibility 0.89
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity 0.96
Enhanced neural plasticity in monkey TE compared to TEO during learning of a feature-ambiguous visual categorization task 0.33
PTEN regulates vagal-insulin signaling to optimize autonomic output determining peripheral inflammatory and metabolic homeostasis 0.06
Autoantibody landscape and functional role of anti-C-C motif chemokine receptor 8 autoantibodies in systemic sclerosis: post-hoc analysis of a B-cell depletion trial 0.73
Structural mechanism of the Retron-Eco7 anti-phage defense system 1.00
Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation 0.96
Methylene blue treatment of fatal cerebral malaria and identification of potential blood biomarkers 0.03
Chromatin remodeling enhances MAP3K8 expression in HAM: a key pathogenesis for therapeutic intervention 1.00
Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes 1.00
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.00
Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome 1.00
Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival 0.17
Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjögren’s disease reveals common and distinct immune activation and fibroblast-mediated inflammation 0.97
Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility 1.00
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes 0.08
ATG7 in innate immune cells is required for host defense against nontuberculous mycobacterial pulmonary infections 0.05
HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation 0.32
Single-cell analysis reveals immune cell abnormalities underlying the clinical heterogeneity of patients with systemic sclerosis 1.00
An unbiased tissue transcriptome analysis identifies potential markers for skin phenotypes and therapeutic responses in atopic dermatitis 0.95
TIGIT deficiency promotes autoreactive CD4+ T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositis 0.06
SARS-CoV-2 virus lacking the envelope and membrane open-reading frames as a vaccine platform 0.28
A protein language model for exploring viral fitness landscapes 0.94
Acellular, bioresorbable, ultra-purified alginate gel implantation for intervertebral disc herniation: Phase 1/2, open-label, non-randomized clinical trials 1.00
Dietary amino acids regulate Salmonella colonization via microbiota-dependent mechanisms in the mouse gut 0.22
1 0.02
Genome-wide association study of long COVID 0.02
2 0.04
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses 0.01
Influenza vaccine based on AS03-adjuvanted chimeric HA induces long-lived stalk-specific plasma cells in bone marrow and lymph nodes of nonhuman primates 0.03
4 0.13
Antisense oligonucleotide-mediated knockdown therapy in two infants with severe epileptic encephalopathy 0.03
Deleterious coding variation associated with autism is shared across ancestries 0.05
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.01
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure 0.04
1 0.04
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine 0.04
2 1.33
A neuromodulatory circuit-to-molecular pathway for reformatting aversive memories during recall 1.00
Temporal-orbitofrontal pathway regulates choices across physical reward and visual novelty 0.33
1 0.82
Aberrant dopaminergic activity during consolidation causes age-related memory generalization in Drosophila 0.82
2 0.20
Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation 0.15
Genetic disease risks of under-represented founder populations in New York City. 0.04
18 13.13
Brain–computer interface–based neurofeedback training enables transferable control of cortical state switching in humans 1.00
Identification of somatostatin+ inhibitory engrams for extinction in the basolateral amygdala 0.03
Ultrasonic vocal communication of negative affective states in laboratory mice 1.00
Negative feedback regulation of alcohol ingestion through the FGF21-PVH oxytocin-VTA dopamine system 0.85
M cell–dependent commensal uptake confers encephalitogenic phenotypes on γδT17 cells in Peyer’s patches 1.00
Neural substrate of conditioned stimulus for associative learning in the hippocampus 1.00
Enhanced insulin signaling via circulating ATG7: A potential therapeutic strategy for diabetes 0.04
Recovery of infectious recombinant human norovirus using zebrafish embryos 1.00
Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer 0.06
Spatial gene expression analysis reveals pathological niches in Japanese encephalitis virus neuroinvasion 0.84
Formation of a complex between TMEM217 and the sodium-proton exchanger SLC9C1 is crucial for mouse sperm motility and male fertility 1.00
DNA polymerase β suppresses somatic indels at CpG dinucleotides in developing cortical neurons 1.00
Phosphatidic acid production on the vacuole harboring Legionella pneumophila is a signal for recognition of interferon-induced GTPases 1.00
Threonine phosphorylation of STAT1 safeguards gut epithelial integrity and restricts interferon-mediated cytotoxicity 0.93
Motilin stimulates food intake linked to gastric motility in Suncus murinus: Simultaneous recordings of food intake and gastric motility in the conscious state 1.00
Contribution of glutamatergic projections to neurons in the nonhuman primate substantia nigra pars reticulata for reactive inhibition 0.25
JunB–HBZ nuclear translocation by TGF-β is a key driver in HTLV-1-mediated leukemogenesis 1.00
Healthy sleep durations appear to vary across cultures 0.14
1 0.08
Intratumoral Microbiome-related MRI Model for Predicting Breast Cancer Shrinkage Pattern Following Neoadjuvant Therapy. 0.08
2 0.70
Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex 0.04
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin 0.67
8 4.54
<atl>Cryo-EM structure of bacteriophage Bas63 reveals structural conservation and diversity in the iFelixounavirus/i genus</atl> 0.25
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate 0.14
Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis 0.06
Dorsomedial striatum monitors unreliability of current action policy and probes alternative one via the indirect pathway 1.00
Phage lysis protein LysM acts as a wedge to block MurJ conformational changes 1.00
Identification of distinct epitopes in dipeptidyl peptidase-4 inhibitor–associated bullous pemphigoid 1.00
Microglial BDNF modulates arketamine’s antidepressant-like effects through cortico-accumbal pathways 0.09
Fibronectin in the olfactory mucus increases sensitivity of olfactory receptor response to odorants 1.00
3 0.16
Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses 0.04
CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice 0.08
Impairment of stromal-epithelial regenerative cross-talk in Hirschsprung disease primes for the progression to enterocolitis 0.03
1 1.00
Comprehensive Integration Framework of CFD – Local and Whole Body Hybrid PBPK in Indoor Chemical Exposure Modeling: An Inhalation Exposure Study 1.00
1 1.00
Effectiveness of screening and ultra-brief intervention for hazardous drinking in primary care: pragmatic cluster randomised controlled trial 1.00
1 1.00
CDKAL1 dysfunction impairs lysine codon translation in podocytes and accelerates chronic kidney disease 1.00
7 3.14
IL-31 blockade elevates thymus and activation-regulated chemokine by lifting LAMP3+CD1c+ mature dendritic cells from calcitonin gene–related peptide–calcitonin receptor–like neuroimmune suppression in atopic dermatitis 0.97
Bimekizumab long-term response in psoriasis: Mechanistic insights into efficacy level and durability 0.06
Epinephrine and Emergency Medical Services Activation Recommendations During Acute Allergic Reactions in Community Settings: International Consensus Report 0.02
Remibrutinib in chronic spontaneous urticaria: 52-Week results from two phase 3 studies 0.09
Periostin promotes inflammation and neovascularization in atopic keratoconjunctivitis 0.91
Effects of type 3 and neutrophilic inflammation on type 2 chronic rhinosinusitis with nasal polyps 0.10
Eosinophil-derived neurotoxin and eosinophil cationic protein are key molecules for blister formation in bullous pemphigoid 1.00
6 0.30
Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on oral antiretroviral therapy: 48-week results of a phase 3, multicentre, randomised, open-label, non-inferiority trial 0.05
Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on bictegravir, emtricitabine, and tenofovir alafenamide: 48-week results of a phase 3, multicentre, randomised, controlled, double-blind, non-inferiority trial 0.05
Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study 0.01
Once-daily oral icotrokinra versus placebo and once-daily oral deucravacitinib in participants with moderate-to-severe plaque psoriasis (ICONIC-ADVANCE 1 & 2): two phase 3, randomised, placebo-controlled and active-comparator-controlled trials 0.03
Efficacy and safety of intravenous induction and subcutaneous maintenance therapy with guselkumab for patients with Crohn's disease (GALAXI-2 and GALAXI-3): 48-week results from two phase 3, randomised, placebo and active comparator-controlled, double-blind, triple-dummy trials 0.05
Once-weekly insulin efsitora alfa versus once-daily insulin degludec in adults with type 2 diabetes currently treated with basal insulin (QWINT-3): a phase 3, randomised, non-inferiority trial 0.11
4 0.30
Safety, tolerability, pharmacokinetics, and efficacy of burosumab in infants with X-linked hypophosphataemia: an open-label, multicentre, non-randomised study 0.07
Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis 0.03
Once‑weekly IcoSema versus once‑weekly insulin icodec in type 2 diabetes management (COMBINE 1): an open‑label, multicentre, treat‑to‑target, randomised, phase 3a trial 0.10
Once-weekly IcoSema versus multiple daily insulin injections in type 2 diabetes management (COMBINE 3): an open-label, multicentre, treat-to-target, non-inferiority, randomised, phase 3a trial 0.10
1 0.09
Efficacy and safety of iclepertin for cognitive impairment associated with schizophrenia (CONNEX programme): results from three phase 3 randomised controlled trials 0.09
5 0.42
Sibeprenlimab in IgA Nephropathy — Interim Analysis of a Phase 3 Trial 0.21
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy 0.05
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension 0.08
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 0.07
Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma 0.02
2 2.00
Balloon dilatation for bronchoscope delivery: first-in-human trial of a novel technique for peripheral lung field access 1.00
Gabapentinoids and risk for asthma exacerbations: a nationwide retrospective cohort study 1.00
2 1.14
Development of Microbial Source Tracking Markers for Detection of Human-Associated Clostridium perfringens 1.00
Carbon composites with photo-allosteric switch for waterborne virus removal 0.14

Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.