Genetics articles for United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 617

Article ‘Count’ for Genetics.

Journal Count Share
1 0.43
De novo variants in KDM2A cause a syndromic neurodevelopmental disorder 0.43
10 4.79
Genome-wide detection of human 5′ UTR variants that impact protein translation 0.33
Genetic variants in ESRRG are associated with a dominant non-progressive congenital movement disorder with ataxia 0.11
Revealing the nervous system requirements of Alzheimer disease risk genes in Drosophila 1.00
Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans 0.15
Distinguishing syndromic and nonsyndromic cleft palate through analysis of protein-altering de novo variants in 818 trios 0.89
Bi-allelic deleterious variants in SNAPIN, which encodes a retrograde dynein adaptor, cause a prenatal-onset neurodevelopmental disorder 0.23
Rare variants in PRKCI cause Van der Woude syndrome and other features of peridermopathy 0.90
Molecular and developmental deficits in Smith-Magenis syndrome human stem cell-derived cortical neural models 0.09
Bi-allelic variants in TM2D3 cause a severe syndromic neurodevelopmental disorder associated with endoplasmic reticulum and mitochondrial abnormalities 0.10
Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children 1.00
1 0.19
Folliculin deletion in the mouse kidney results in cystogenesis of the loops of Henle via aberrant TFEB activation 0.19
2 1.33
Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells 1.00
Setup and Evaluation of the TRACT Assay Principle for the iIn Vitro/i Functional Characterization of Modulators of the Serotonin Transporter and the Serotonin 2A Receptor 0.33
4 2.18
Chemically Synthesized H3K14Ub Unveils Clr4's IDR-Mediated Multivalent Nucleosome Recognition in H3K9 Methylation 0.06
Degradation of G‐Quadruplex‐Binding Proteins by G4L‐PROTAC via Quaternary Complex Formation 0.38
Conformational Change in a Four-Tetrad DNA G-Quadruplex upon Intercalation of a Small-Molecule Ligand PyDH2 0.75
Machine Learning‐Augmented Molecular Dynamics Simulations (MD) Reveal Insights Into the Disconnect Between Affinity and Activation of ZTP Riboswitch Ligands 1.00
3 1.87
The Age at Onset of LRRK2 p.Gly2019Ser Parkinson's Disease Across Ancestries and Countries of Origin 0.14
Diverse Genetic Etiologies of Unilateral Polymicrogyria 0.73
Non-Synaptic Function and Localization of Syntaxin-Binding Protein 1 in a Mouse Model of STXBP1-Related Epileptic Encephalopathy 1.00
1 1.00
Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis 1.00
1 1.00
An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis 1.00
7 3.32
Long-read sequencing identifies FGF14 repeat expansions in Parkinson’s disease 0.85
Microgliosis and aberrant interferon response in Adar Mavs brain are rescued by PKR removal 0.23
TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes 0.64
POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population 1.00
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder 0.37
The genetic and phenotypic spectrum of iGABRB1/i-related disorders 0.19
Biallelic iLGI1/i and iADAM23/i variants cause hippocampal epileptic encephalopathy via the LGI1–ADAM22/23 pathway 0.04
2 1.08
Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer. 0.08
LSD1 Inhibition Induces MHC-I and Dendritic Cell Activation to Promote Antitumor Immunity in Head and Neck Squamous Cell Carcinoma. 1.00
10 6.60
Genome instability triggers intercellular DNA transfer between human cells 0.75
Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states 0.99
Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life 0.75
FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of gene expression in cancer 0.08
Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis 1.00
Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation 1.00
Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism 0.09
Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses 0.20
Bivalent chromatin instructs lineage specification during hematopoiesis 0.83
Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes 0.90
2 2.00
Species-specific chromatin architecture and neurogenesis mediated by a human enhancer 1.00
Multi-omic analysis reveals retinoic acid molecular drivers for dermal fibrosis and regenerative repair in the skin 1.00
1 1.00
A guanosine-containing nucleopeptide self-assembles at the Hoogsteen face to act as a peroxidase mimetic 1.00
1 0.25
Structural dynamics of DNA mimic foldamers 0.25
2 0.93
DAPK2 Regulates PKM2 Phosphorylation at Threonine 45 to Facilitate Disturbed Flow-Induced Atherosclerosis. 0.06
DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases. 0.88
14 11.99
Rapid transcriptional response to a dynamic morphogen by time integration 0.75
An X-to-autosome-to-Y chromosome amplified retrogene family functions in spermatids 1.00
Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore morphogenesis 0.38
Oligomerization and positive feedback on membrane binding stabilize PAR-3 asymmetries in the C. elegans zygote 1.00
Tetrahymena JanusA gene encodes a polo kinase whose loss triggers a dorsal/ventral intracellular homeosis 0.93
A reference brain for the clonal raider ant 1.00
Spatiotemporal dynamics of CYCLOIDEA expression during early floral development in monkeyflower 1.00
Crossover designation recruits condensin to reorganize the meiotic chromosome axis 0.71
Mitochondria transported by Kinesin-3 prevent localized calcium spiking to inhibit caspase-dependent specialized cell death 1.00
Insulin signaling activity in the somatic gonad controls dauer entry via the germ line in C. elegans 1.00
Dynamic control of Argonautes by a rapidly evolving immunological switch 0.22
Negative feedback equalizes polarity sites in a multi-budding yeast 1.00
Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos 1.00
Cell fate ratios are encoded by transcriptional dynamics in the Drosophila retina 1.00
5 3.13
Host-transposon mutualism supports regeneration in planarians 1.00
Pulsatile dynamics propagate crystalline order in the developing Drosophila eye 0.06
Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation center 0.95
Molecular profiling of adult C. elegans glia across sexes by single-nuclear RNA-seq 1.00
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila 0.11
1 0.11
Prenatal Exposure to benzene, toluene, ethylbenzene, and xylene (BTEX) and the Risk of Autism Spectrum Disorders in Children Aged 16 to 37 Months: A Prospective Cohort Study 0.11
2 1.56
Epigenome-wide association study of household air pollution exposure in an area with high lung cancer incidence 0.56
Prenatal Heat and Air Pollution Exposure Alter Progesterone and Child Behavior: A Longitudinal Study 1.00
13 10.47
A dual role for cGAS in shaping cellular and organismal responses to genomic instability 0.17
DAXX directs dual modes of H3.4-to-H3.3 histone replacement in the male germline 0.75
mRNA 3′ UTRs direct microRNA degradation to participate in imprinted gene networks and regulate growth 1.00
A lncRNA drives developmentally timed decay of all members of an essential microRNA family 1.00
The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity 1.00
Retrotransposon activation during spermatogenesis achieves massive ecDNA biogenesis but rare integration 1.00
Exosome-mediated decay of unstable long extended precursors of human telomerase RNA is dependent on 5′-cap trimethylation 0.86
Hunchback functions in the postmitotic larval MDN to restrict axon outgrowth, synapse formation, and backward locomotion 1.00
Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503 0.70
Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repression 0.33
An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis independent of tissue-specific Microprocessor condensates 1.00
Multiple human enhancer RNAs contain long translated open reading frames 0.67
A noncanonical Pol III-dependent, Microprocessor-independent biogenesis pathway generates a germline-enriched miRNA family 1.00
12 6.82
R-loops shape the H2A.Z landscape and promote balanced lineage allocation during differentiation 1.00
Epigenetic characterization of pseudogenes across human tissues 1.00
ACTB methylation regulates SMARCA4 genomic occupancy to promote translation and reduce adhesion in colorectal cancer cells 0.17
Haplotype-resolved telomere-to-telomere genome of Aphelenchus avenae implicates P5CS in nematode desiccation stress response 0.22
Transposable elements contribute to the evolution of host shift–related genes in cactophilic Drosophila species 0.04
Cell type-specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease 1.00
Autism spectrum disorder–risk genes have convergent effects on transcription and neuronal firing patterns in primary neurons 1.00
Quadrupia provides a comprehensive catalog of G-quadruplexes across genomes from the tree of life 0.58
Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-kB binding 0.11
Developmental transcriptomics iniPristionchus/ireveals the environmental responsiveness of a plasticity gene-regulatory network 0.67
Charting the regulatory landscape of TP53 on transposable elements in cancer 1.00
Continuous infiltration and evolutionary trajectory of nuclear organelle DNA iniOryza/i 0.04
1 0.08
SWS1-complex in premature ovarian insufficiency: iSWSAP1/i as a new POI gene 0.08
2 1.89
Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells 1.00
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway 0.89
24 21.71
KMT2D depletion promotes KRAS-induced pancreatic carcinogenesis independent of TP53 1.00
Stable maintenance of MERVL-positive embryonic stem cells reveals sustained transcriptional programs and enhancer remodeling 1.00
Functional characterization of UHRF1 variants in facilitating DNA methylation 1.00
Cleavage of histone H2A during embryonic stem cell differentiation destabilizes nucleosomes to counteract gene activation 1.00
KDM5A methylation modulates its genomic demethylase and transcriptional actions 1.00
Structural basis for the mechanism and stability of the EEPD1 5′ endonuclease 1.00
TOP1 and TOP2 complementarily maintain DNA replication fork progression in vertebrates 0.29
Thymine DNA Glycosylase Binds to R-Loops and Excises 5-Formyl and 5-Carboxyl Cytosine from DNA/RNA Hybrids 1.00
Mechanisms of DNA methyltransferase 3A1-mediated DNA methylation of nucleosomes 1.00
The SETD2 L1609P mutation found in leukemia disrupts methyltransferase activity and reduces histone H3K36 trimethylation 0.10
A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3 0.50
Targeted delivery of rhodopsin’s assembled core is required for outer segment extension in mouse rod photoreceptors 1.00
Rapid DNA Cleavage by the LINE-1 Endonuclease Proximal to DNA Ends and at Mismatches 0.97
4E-BP1 differentially regulates translation of a subset of human mRNAs 1.00
Multiple modes of transcriptional regulation by the nuclear hormone receptor RARγ in human squamous cell carcinoma 1.00
Conserved +1 translational frameshifting in the Saccharomyces cerevisiae gene encoding YPL034W 1.00
Structural Interactions of Ankyrin B with NrCAM and β2 Spectrin 1.00
Jade1 and the HBO1 histone acetyltransferase complex are spatial-selective cofactors of the pluripotency transcription factor Oct4 0.86
DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation 1.00
Apolipoprotein E (APOE) regulates the transport of monosialotetrahexosylganglioside (GM1) 1.00
The bacterial tRNA-modifying enzyme tRNAIle lysidine synthetase is genetically conserved but catalytically variable 1.00
APE1 active site residue Asn174 stabilizes the AP site and is essential for catalysis 1.00
Synergy between RNA editing and alternative splicing modulates the biological properties of the voltage-gated calcium channel CaV1.3 1.00
Characterization of the activity of KTX-1001, a small molecule inhibitor of multiple myeloma SET domain using surface plasmon resonance 1.00
4 3.73
Early resolution of sister chromatids during C. elegans meiosis 1.00
Arc controls organ architecture through modulation of Crb and MyoII 0.88
PLK-1 suppresses centrosome maturation and microtubule polymerization to ensure faithful oocyte meiosis 1.00
CNTD1 is crucial for crossover formation in female meiosis and for establishing the ovarian reserve 0.86
8 5.85
Loss of Kmt2c/d promotes gastric cancer and confers vulnerability to mTORC1 and PD1 inhibition 1.00
T cell receptor signaling induces expression of lysine demethylase KDM6B to maintain Treg homeostasis 1.00
Methyltransferase complex subunit METTL3 maintains genome stability of erythroid cells via MTHFD1-mediated nucleotide biosynthesis 0.06
MRE11 deacetylation by SIRT2 promotes DNA binding to facilitate DNA end resection and ATM-dependent signaling 1.00
Functional consequence of pathogenic GABRA3 variants determines whether X-linked inheritance is dominant or recessive 0.33
EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway 0.88
Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas 0.76
Somatic mutations in TBX3 promote hepatic clonal expansion by accelerating VLDL secretion 0.81
1 0.26
Higher Promoter Methylation of the Ubiquitin-Associated and SH3 Domain Containing A (UBASH3A) Gene Is Associated With T-Lymphocyte Ontogeny and Reduced Susceptibility to Early-Onset Sepsis 0.26
3 3.00
Ribosomal Profiling of the Geniculate Ganglion Identifies the Receptor ALK as Critical for the Development and Maintenance of Oral Sensory Neurons 1.00
Kv4.2V404M Mutation Induces Epileptiform Activity and Multiple Behavioral Abnormalities in Heterozygous Knock-in Mice 1.00
A Novel Mouse Model for Developmental and Epileptic Encephalopathy by Purkinje Cell-Specific Deletion of Scn1b 1.00
1 0.22
Differential negative dominance by KCNA2 variants associated with global developmental delay suggests KCNA2 haploinsufficiency in humans 0.22
7 6.01
Enzyme-Mediated Covalent Labeling Enables In Situ Imaging of RNA Modification States 1.00
Protein–Protein Cross-Linking by a DNA Damage-Derived Histone Modification 1.00
YY1 Interacts with Promoter R-Loops to Regulate Transcription 1.00
Assembling Ternary Dead-End Complex for Covalent Trapping of Protein Lysine Methyltransferases 1.00
Synthesis of Precisely Modified Ribonucleic Acid to Reveal the Site-Specific Effect of Modification on Message Ribonucleic Acid Translation 0.10
Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch 1.00
Designing Reversible Photoswitching Azobenzene-Modified Nucleotide for Controlling Biological Function 0.91
1 1.00
Association of Early Life Risk Factors and scpAPOE/scp ε4 With Incident Dementia: Evidence From 14 Years of U.S. Data 1.00
2 1.98
Testican-2 Interaction with the Extracellular Matrix and Podocyte Protection. 0.98
Podocyte-Specific Deletion of STAT3 in KLF4-Related Experimental Podocytopathy. 1.00
17 13.01
Molecular mechanisms of the MLL4 complex in H3K4 methylation and p53-dependent transcription activation 0.85
Nucleosome spacing regulates linker methylation by DNMT3A2/3B3 1.00
Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders 0.84
GCN2 monitors mRNA translation termination 1.00
NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA 1.00
Rate-limiting enzymes in nucleotide metabolism synchronize nucleotide biosynthesis and chromatin formation 1.00
Transcription-replication conflict resolution by nuclear RNA interference 0.64
Dcr1 senses R-loops for RNAPII termination at sites of replication stress and repair pathway choice 0.25
The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity 1.00
A conserved PIWI silencing complex detects piRNA-target engagement 1.00
Human mitochondrial RNA polymerase structures reveal transcription start site and slippage mechanism 0.50
Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers 1.00
The SWI/SNF-related protein SMARCA3 is a histone H3K23 ubiquitin ligase that regulates H3K9me3 in cancer 1.00
The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance 0.15
Synaptic activity causes minute-scale changes in BAF complex composition and function 1.00
Vostok: A looping factor for the organization of the regulatory genome in the Drosophila brain 0.43
A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma 0.35
27 16.96
Assessing the de novo paradigm in sporadic early-onset Alzheimer disease trios 0.01
Elevated microbially-derived metabolites in autism: a possible diagnostic screening test for a distinct ASD phenotype 0.91
Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na+ channel dynamics in human neurons 0.80
Genome-wide tandem repeat expansions modify schizophrenia risk in the presence of a 22q11.2 deletion 0.34
Towards scalable biomarker discovery in posttraumatic stress disorder: triangulating genomic and phenotypic evidence from a health system biobank 0.97
Neuronal HDAC9: A key regulator of cognitive and synaptic aging, rescuing Alzheimer’s disease-related phenotypes 1.00
Inflammation increases the penetrance of behavioral impairment in haploinsufficiency mice — can it explain the behavioral regression in Autism? 0.70
Uncoupling memory impairments from autism-associated behaviors in Chd2 deficient mice 1.00
Nitric Oxide-Mediated S-Nitrosylation of TSC2 Drives mTOR dysregulation across Shank3 and Cntnap2 Models of Autism Spectrum Disorder 0.08
miR126-mediated alteration of vascular integrity in Rett syndrome 1.00
Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer’s disease 1.00
UBE3A isoform-selective and non-selective contributions to Angelman syndrome phenotypes 0.78
Associations between mosaic loss and schizophrenia or bipolar disorder of young age 0.11
RO4938581, a GABAA-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome 0.07
Aberrant expression of long non-coding RNAs and their regulatory role in chromatin-mediated gene expression changes in the prefrontal cortex of major depressive disorder subjects 1.00
Disrupted Development of the mPFC-Thalamic Circuit in Shank3–/– mice, an autism-associated model 1.00
3D genetic architecture of schizophrenia risk across three neuronal subtypes 0.94
Investigating milk-derived extracellular vesicles as mediators of maternal stress and environmental intervention 0.73
Connectome-based symptom mapping and in silico related gene expression in children with autism and/or attention-deficit/hyperactivity disorder 0.72
Increased expression of ATase1/NAT8B or ATase2/NAT8 in the mouse results in an autistic-like phenotype with altered dendritic branching and spine formation 1.00
Polygenic Risk and Exposure Severity Predict Trajectories of PTSD: A Prospective Cohort Study 1.00
Mutations of schizophrenia risk gene SETD1A dysregulate synaptic function in human neurons 1.00
A phenome-wide association and Mendelian randomization study for suicide attempt within UK Biobank 0.20
Aberrant neural stem cell quiescence is the gateway to autism development linked to Arid1b 0.19
Probiotics derived sodium benzoate improves social behavior of offspring exposed in the maternal immune activation through regulation of histone lysine benzoylation in astrocytes 0.13
Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies 0.09
Distinct and shared intrinsic resting-state functional networks in children with idiopathic autism spectrum disorder and fragile X syndrome 0.20
26 18.57
Substrate selectivity of the human RNA m5C methyltransferase NSUN2 1.00
An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism 0.10
Expanding the human proteome with microproteins and peptideins 0.39
DNA damage burden causes selective CUX2 neuron loss in neuroinflammation 0.53
Developmental organization of sensory and sympathetic ganglia 0.84
The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation 0.63
Mechanism of co-transcriptional cap snatching by influenza polymerase 0.04
Nucleotide signals coordinate activation and inhibition of bacterial immunity 0.67
Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness 1.00
Developmental convergence and divergence in human stem cell models of autism 1.00
PAF15–PCNA exhaustion governs the strand-specific control of DNA replication 0.03
CFAP20 salvages arrested RNAPII from the path of co-directional replisomes 0.04
An RNA splicing system that excises DNA transposons from animal mRNAs 1.00
Viral RNA blocks circularization to evade host codon usage control 1.00
An ancient recombination desert is a speciation supergene in placental mammals 1.00
Secretome translation shaped by lysosomes and lunapark-marked ER junctions 1.00
Transcriptional interferences ensure one olfactory receptor per ant neuron 0.86
KCTD10 is a sensor for co-directional transcription–replication conflicts 1.00
A human-specific regulatory mechanism revealed in a pre-implantation model 0.92
Protecting double Holliday junctions ensures crossing over during meiosis 1.00
CRISPR activation for SCN2A-related neurodevelopmental disorders 0.99
NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers 0.71
Mechanism of cytarabine-induced neurotoxicity 0.71
Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD 1.00
Dynamic assemblies and coordinated reactions of non-homologous end joining 1.00
Subnucleosome preference of human chromatin remodeller SMARCAD1 0.13
3 1.55
Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs 0.13
Programmable initiation of mRNA translation by trans-RNA 0.71
RNA structure modulates Cas13 activity and enables mismatch detection 0.71
12 7.24
NAT10 maintains stem cell homeostasis by mitigating mRNA decay through an acC-independent mechanism 0.08
ATM counteracts chromatin-bound cGAS during DNA replication 1.00
-adenosine methylation enhances nuclear mRNA export through METTL3 and NUP93 0.83
DOT1L provides transcriptional memory through PRC1.1 antagonism 0.10
ER remodelling is a feature of ageing and depends on ER-phagy 1.00
Escape from X inactivation is directly modulated by Xist noncoding RNA 0.11
Transcription factors instruct DNA methylation patterns in plant reproductive tissues 1.00
A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate 1.00
Two microbiome metabolites compete for tRNA modification to impact mammalian cell proliferation and translation quality control 0.60
REM transcription factors and GDE1 shape the DNA methylation landscape through the recruitment of RNA polymerase IV transcription complexes 0.80
A lysosomal surveillance response to stress extends healthspan 0.10
Crossover patterning through condensation and coarsening of pro-crossover factors 0.63
4 3.60
MED1 IDR deacetylation controls stress responsive genes through RNA Pol II recruitment 1.00
Enhancing RNA base editing on mammalian transcripts with small nuclear RNAs 1.00
A Ψ–Ψ codon–anticodon pairing in nonsense suppression and translational recoding 0.60
Designing small molecules targeting a cryptic RNA binding site through base displacement 1.00
1 0.18
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9 0.18
151 102.59
Mitochondrial RNA degradation regulates differentiation, stemness, and immune sensitivity in acute myeloid leukemia 0.05
Cuproptosis inducers mediate cold lethality via SLCR-46.1 in 0.25
Recognition and silencing of a new transposable element 0.67
Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and replication fork protection 0.97
Topological stress regulates replication fork dynamics in unperturbed S phase 0.89
H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers 1.00
A tunable CTD grammar governs the spatial programming of the transcription cycle 0.90
Hierarchical small molecule inhibition of MYST acetyltransferases 1.00
Base modifications shift tertiary structure and activity in synthetic RNA origami and a natural ribozyme 1.00
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trials 0.80
Condensin and topoisomerases cooperate to relieve topological stress at stalled replication forks 0.18
A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response 0.38
Cathepsin B protease mediates high population density-induced mutagenesis to drive genome evolution and competitive growth 0.64
Crystallized and fluid cognitive abilities have different genetic associations with neuropsychiatric disorders 0.57
RNA-induced PRC2 inhibition depends on the sequence of bound RNA 1.00
Functional requirement for Dicer helicase arginine methylation in 26 G siRNA biogenesis and oocyte meiotic program 1.00
Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily 0.30
Cytoplasmic localization of pseudouridine synthase 7 facilitates a pseudouridine-dependent enhancement of cellular stress tolerance 1.00
The effect of the fitness gradient on fixation probability 0.10
POMC neuron METTL14/m6A/YTHDC1/YTHDF2 pathways safeguard energy balance, body weight, and metabolism 1.00
Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cortical organoids 0.94
Astrocyte fatty acid metabolism as a driver of risk for major depressive disorder 0.14
Establishment of DNA methylation during primate germ cell development 0.12
PHIP suppresses NuRD to enable the growth of SWI/SNF-mutant cancers 1.00
Recruitment of Mre11 to recombination sites during meiosis 0.25
Downregulated transcription in chromosomal domains of midbrain dopamine neurons linked to schizophrenia 1.00
Mechanisms of human mitochondrial leaderless mRNA translation initiation 1.00
Trisomy 21 Drives Overexpression and Premature RNA Recoding in the Developing Fetal Brain 0.67
An unbiased approach to measure aberrant DNA methylation alterations 0.88
A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR 0.93
Genetic nurture in intergenerational transmission of substance use 0.13
Hh and EGFR-Ras signaling promote distinct steps of tumor progression in the Drosophila follicle epithelium 0.33
Enzyme-mediated alkynylation enables transcriptome-wide identification of pseudouridine modifications 1.00
RNA functional modulation by Mitoxantrone via RNA structural ensemble repartitioning 0.08
tRNA-derived RNA processing in sperm transmits non-genetically inherited phenotypes to offspring in C. elegans 1.00
Hypusination of the translation factor eIF5A regulates mitochondrial tRNA processing to promote prostate cancer aggressiveness 0.09
Gene expression dynamics of human and mouse craniofacial development at the single-cell level 0.78
p38 MAPK orchestrates cross-tissue potassium homeostasis for survival 0.09
AMR-GNN: a multi-representation graph neural network framework to enable genomic antimicrobial resistance prediction 0.07
Integrative epigenomic landscape of Alzheimer’s Disease brains reveals oligodendrocyte molecular perturbations associated with tau 1.00
Unifying non-Markovian dynamics and agent heterogeneity in scalable stochastic networks 0.10
Quantitative mapping of pseudouridines in bacterial RNA 1.00
Male obesity causes adipose mitochondrial dysfunction in F mouse progeny via a let-7-DICER axis 0.03
Crosstalk between EZH2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity 1.00
Reducing methylation of histone 3.3 lysine 4 in the medial ganglionic eminence and hypothalamus recapitulates neurodevelopmental disorder phenotypes 0.96
Co-transcriptional folding orchestrates sequential multi-effector sensing by a glycine tandem riboswitch 1.00
Structures of the eIF4G-binding RNA domains among picornaviral IRES types are topologically conserved 1.00
Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity 0.97
Genetic regulation of methylation across East Asian and European populations 0.56
Viral mimicry acts as a tumor suppressor in colitis 0.11
A common 19 bp APOE enhancer deletion is protective against Alzheimer’s disease in African Americans 1.00
ALKB-1-dependent tRNA methylation is required for efficient paternal mitochondrial elimination 0.08
NR6A1 is essential for neural crest cell specification, formation and survival 0.73
Human brain prefrontal cortex proteomics identifies compromised energy metabolism and neuronal function in Schizophrenia 0.18
The proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth 1.00
Repeatability of gene expression evolution in experimental environmental adaptation 1.00
Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1 0.73
Silencing lipid catabolism determines longevity in response to fasting 1.00
WDR5 remodels NANOG condensates to drive transcriptional programs and sustain stem cell identity 0.12
Biochemical principles of miRNA targeting in flies 0.67
Molecular determinants of Smc5/6 association with DNA junctions 1.00
Haldane’s law works through X:Autosome incompatibility in Caenorhabditis briggsae/C. nigoni hybrids 1.00
EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization 1.00
A chromosome region linked to neurodevelopmental disorders influences locomotor behavior through sex-specific neural circuits 0.92
A north-south hemispheric migratory divide in the butterfly Vanessa cardui 0.15
Cryo-EM structures of NHEJ assemblies with nucleosomes 0.05
SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia 0.90
H2AK119ub dynamics control hair follicle stem cell quiescence 1.00
Genetic architecture and mechanisms of host-microbiome interactions from a multi-cohort analysis of outbred laboratory rats 0.81
METTL3 safeguards cell identity and epigenome of human trophoblast stem cells 0.02
A cholesterol-responsive hepatic tRNA-derived small RNA regulates cholesterol homeostasis and atherosclerosis development 1.00
Cell type-specific functions of the PBAF chromatin-remodeling complex in neuronal diversification 0.86
Mass spectrometry-based profiling of single-cell histone post-translational modifications to dissect chromatin heterogeneity 0.75
unctionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagy 1.00
Mechanism of RPA phosphocode priming and tuning by CDK1/WEE1 signaling circuit 1.00
Nuclear effects play an important role in determining codon usage-dependent human gene expression 1.00
Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy 0.97
Dietary lipid content modifies wah-1/AIFM1-associated phenotypes via LRK-1 and DRP-1 expression in C. elegans 0.13
Mechanistic insights into histone recognition and H3K14 acetylation by the NuA3 histone acetyltransferase complex 0.06
Maternal histone methyltransferases antagonistically regulate autosomal random monoallelic expression (aRMAE) in C. elegans 1.00
The alkenes Z9-C and Z9-C function as quorum-sensing pheromones stimulating worker reproduction in the bumble bee 0.14
Interferometric imaging of the reversible rhodopsin dynamics in the living rat eye 0.80
An antagonistic epigenetic mechanism regulating gene expression in pollen revealed through single-nucleus multiomics 1.00
Convergent flow-mediated mesenchymal force drives embryonic foregut constriction and splitting 0.90
H3K4me2 orchestrates H2A.Z and Polycomb repressive marks in Arabidopsis 0.07
Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila 0.18
Crossover interference mediates multiscale patterning along meiotic chromosomes 1.00
mop1 affects maize recombination landscapes by modulating methylation of MITEs near genes in open chromatin 1.00
Context-dependent serotonin signaling links dietary quality to foraging decisions 1.00
Nonhomologous end-joining uses distinct mechanisms to repair each strand of a double strand break 1.00
Immunological surveillance against cancer across mammals 0.12
Serum Proteomics Reveals Diagnostic Biomarkers and Molecular Pathways in Cerebral Palsy 0.05
Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress 1.00
YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis 1.00
Dynamic dosage changes in X-linked transposable elements during mammalian dosage compensation 1.00
HIRA defines early replication initiation zones independently of their genome compartment 0.13
Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice 0.77
Pseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation 1.00
Different gametogenesis states uniquely impact longevity in Caenorhabditis elegans 1.00
SETBP1 variants outside the degron disrupt DNA-binding, transcription and neuronal differentiation capacity to cause a heterogeneous neurodevelopmental disorder 0.03
ZMYND11 functions in bimodal regulation of latent genes and brain-like splicing to safeguard corticogenesis 0.96
Quantitative CRACI reveals transcriptome-wide distribution of RNA dihydrouridine at base resolution 0.76
SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis 0.85
Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA 1.00
RNA polymerase II is a polar roadblock to a progressing DNA fork 1.00
DNA2 and MSH2 cooperatively repair stabilized G4 and allow efficient telomere replication 0.96
Structural basis of antiphage defence by an ATPase-associated reverse transcriptase 1.00
Synaptic vesicle endocytosis deficits underlie cognitive dysfunction in mouse models of GBA-linked Parkinson’s disease and dementia with Lewy bodies 0.95
Multiple independent acquisitions of a metallophore-synthesis gene by plants through horizontal microbial gene transfer 0.11
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation 0.50
Controlling intermolecular base pairing in Drosophila germ granules by mRNA folding and its implications in fly development 1.00
GraphVelo allows for accurate inference of multimodal velocities and molecular mechanisms for single cells 0.79
Nanopore sequencing of intact aminoacylated tRNAs 0.94
Transposable element expression and sub-cellular dynamics during hPSC differentiation to endoderm, mesoderm, and ectoderm lineages 0.04
Dopamine signaling drives skin invasion by human-infective nematodes 1.00
Unique metabolic regulation of micromeres contributes to gastrulation in the sea urchin embryo 0.80
An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting 1.00
Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics 1.00
RNAi epimutations conferring antifungal drug resistance are inheritable 0.67
A light-resuming strategy as a screening method for selecting Sec61 inhibitors down-modulating PD-L1 expression 0.12
The RING finger E3 ligase RNF25 protects DNA replication forks independently of its canonical roles in ubiquitin signaling 1.00
Limits on the computational expressivity of non-equilibrium biophysical processes 1.00
Latent infection of by Orsay virus induces age-dependent immunity and cross-protection 0.07
linked myelination deficits and synaptic plasticity alterations drive auditory processing disorders in an ASD mouse model 1.00
Aberrant pace of cortical neuron development in brain organoids from patients with 22q11.2 deletion syndrome-associated schizophrenia 1.00
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers 0.04
The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life 1.00
Removal of promoter CpG methylation by epigenome editing reverses silencing 0.59
Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures 0.60
Somites are a source of nephron progenitors in zebrafish 0.11
The histone H3 lysine 36 demethylase KDM2A/FBXL11 controls Polycomb-mediated gene repression and germ cell development in male mice 0.47
Identification of functional non-coding variants associated with orofacial cleft 1.00
ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis 0.06
sperm and oocytes differentially transmit diet-induced adaptations to their progeny 1.00
Comprehensive resolution and classification of the Epstein Barr virus transcriptome 1.00
Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor 1.00
Targeting microRNA-dependent control of X chromosome inactivation improves the Rett Syndrome phenotype 1.00
A cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific m5C modification 0.08
Single-cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism 1.00
Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome 0.67
Immuno-metabolic stress responses control longevity from mitochondrial translation inhibition in C. elegans 0.08
A Hedgehog–Foxf axis coordinates dental follicle-derived alveolar bone formation 0.83
Isoform characterization of m6A in single cells identifies its role in RNA surveillance 0.16
Autoregulation of the real-time kinetics of the human mitochondrial replicative helicase 0.22
Histone lysine methyltransferases MLL3 and MLL4 direct gene expression to produce platelets efficiently 0.88
Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy 0.82
BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication 1.00
Rim4-seeded stress granules connect temperature sensing to meiotic regulation 1.00
USP37 prevents premature disassembly of stressed replisomes by TRAIP 0.25
Translation suppresses exogenous target RNA-mediated microRNA decay 1.00
Rewired m6A of promoter antisense RNAs in Alzheimer’s disease regulates neuronal genes in 3D nucleome 1.00
7 3.26
Biallelic variants in cause a remarkably frequent developmental and epileptic encephalopathy 0.01
Genetics and environment distinctively shape the human immune cell epigenome 0.91
Pathogenic variants cause a neurodevelopmental syndrome by impairing synaptic function 0.29
Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer 0.99
Bryophytes hold a larger gene family space than vascular plants 0.12
Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue 0.81
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression 0.14
1 1.00
Loss of YTHDF2 enhances Th9 programming and CAR-Th9 cell antitumor efficacy 1.00
3 1.96
Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function 1.00
APOE ε4 carriers share immune-related proteomic changes across neurodegenerative diseases 0.77
The UBE3A-ATS antisense oligonucleotide rugonersen in children with Angelman syndrome: a phase 1 trial 0.19
6 4.63
Autism subtypes identified using cross-species functional connectivity analyses 0.17
Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the optic lobe 0.46
Genetic mapping identifies as a developmental modifier of attention 1.00
Multi-region mA epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci 1.00
to allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition 1.00
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development 1.00
1 0.83
chemosensing accuracy is not limited by stochastic molecule arrivals 0.83
9 7.02
Distinct repair outcomes from single and convergent replication fork collapse 1.00
Dynamic regulation of H3K9 dimethylation drives mouse minor zygotic genome activation 0.06
Resolution of R-loops and transcription–replication conflicts by SETX–BRCA1–BARD1 complex 1.00
Transposable element–gene chimera cartography, origination and role in enhancing transcriptome plasticity 0.88
Cell-cycle-dependent repression of histone gene transcription by histone H4 1.00
Human DICER1 hotspot mutation induces both loss and gain of miRNA function 1.00
Mechanisms of DNMT3A–3L-mediated de novo DNA methylation on chromatin 1.00
tRNA as an assembly chaperone for a macromolecular transcription-processing complex 0.08
eIF1 and eIF5 dynamically control translation start site fidelity 1.00
3 2.06
Protective ApoE variants support neuronal function by effluxing oxidized phospholipids 0.15
A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy 0.91
Cell-type-specific enrichment of somatic aneuploidy in the mammalian brain 1.00
13 9.99
Genetic parallelism underpins convergent mimicry coloration in Lepidoptera across 120 million years of evolution 0.10
Integrated chromatin and transcriptomic profiling reveals sex-specific mechanisms of gene regulation in hepatic nutrient responses 1.00
Dynamic auxin maxima regulate male-to-hermaphrodite conversion and de novo meristem formation in the fern Ceratopteris gametophytes 1.00
A male-transmitted B chromosome undergoes strong meiotic drag in females of the jewel wasp Nasonia vitripennis 1.00
Biased sampling driven by bacterial population structure confounds machine learning prediction of antimicrobial resistance 0.17
Distinct S-adenosylmethionine synthases link phosphatidylcholine to mitochondrial function and stress survival 1.00
New retron systems from environmental bacteria identify triggers of anti-phage defense and expand tools for genome editing 0.80
XDH-1 inactivation causes xanthine stone formation in Caenorhabditis elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell 1.00
Genetic variation influences food-sharing sociability in honey bees 0.78
Active DNA demethylation upstream of rod-photoreceptor fate determination is required for retinal development 1.00
Altered auditory feature discrimination in a rat model of Fragile X Syndrome 1.00
Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies 0.85
Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma 0.31
26 22.83
INS-17 acts as a nutrient deprivation signal to mediate adult IIS-regulated associative behaviors in C. elegans 1.00
Chronic replication stress-mediated genomic instability disrupts placenta development in mice 1.00
The RPA-binding domain and the KKRK motif in Rad26ATRIP cooperate at the perturbed DNA replication fork for initiating checkpoint signalling 0.63
The rewiring of a terminal selector regulatory cascade generates convergent neuronal laterality 1.00
The regenerative period of somatosensory nerves is closed by a DCC signaling axis 1.00
A C. elegans model of copper deficiency: Dietary interventions rescue CTR1/CHCA-1 copper transporter mutant phenotype 0.30
Temperature and genetic background drive mobilization of diverse transposable elements in a global human fungal pathogen 1.00
Cosmopolitan inversions have a major impact on trait variation and the power of different GWAS approaches to identify associations 1.00
LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death 1.00
LIPL-1 and LIPL-2 are TCER-1-regulated lysosomal lipases with distinct roles in immunity and fertility 1.00
Single-cell transcriptomics reveals stepwise transformation of epithelial cells into Non-Professional Phagocytes 1.00
Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental pathology in adult C. elegans 0.71
MYCBP interacts with Sakura and Otu and is essential for germline stem cell renewal and differentiation and oogenesis 1.00
Modeling the length distribution of gene conversion tracts in humans from the UK Biobank sequence data 1.00
METTL3 facilitates the translation of CircSIK2 during chicken myogenesis in an m6A dependent manner 0.13
Loss of meiotic double strand breaks triggers recruitment of recombination-independent pro-crossover factors in C. elegans spermatogenesis 0.56
Probing the molecular determinants of Ty1 retrotransposon restriction specificity in yeast 0.67
A high-resolution crossover landscape in Drosophila santomea reveals rapid and concerted evolution of multiple properties of crossing over control 1.00
Variants in CALD1, ESRP1, and RBFOX1 are associated with orofacial cleft risk 0.84
The Drosophila mauritiana synaptonemal complex protein C(3)G repatterns the recombination landscape of Drosophila melanogaster. 1.00
Distinct cellular and reproductive consequences of meiotic chromosome synapsis defects in syce2 and sycp1 mutant zebrafish. 1.00
MIG-21 interacts with Wnt and Netrin signaling in gonad migration in C. elegans 1.00
Genetic and environmental influences on the distributions of three chromosomal drive haplotypes in maize 1.00
Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity 1.00
Fitness consequences of sex chromosome aneuploidy in Drosophila melanogaster 1.00
Drosophila Trus, the orthologue of mammalian PDCD2L, is required for proper cell proliferation, larval developmental timing, and oogenesis 1.00
1 1.00
Evolutionary Benefits of Fitness-Dependent Mutation Rates 1.00
62 45.26
Genome-wide CG hypomethylation of the Arabidopsis ecotype Cvi linked to structural variation and RNAi at the VIM4–VIM2 locus 0.13
MHC-I diversity enables rapid adaptation during a viral pandemic in wild rabbit populations 0.05
A molecular timer couples organism-wide temporal identity to developmental checkpoints 1.00
The heterogeneous selection landscape of genome evolution in prokaryotes 1.00
Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers 1.00
Mecp2 deficiency induces dysphagia in a preclinical model of Rett syndrome 1.00
YTHDC1 recognizes METTL16-dependent m6A on caRNAs and coordinates cotranscriptional splicing 0.07
Exploring functional transitions of the 2’-dG riboswitch aptamer 1.00
Simulation-based inference captures non-Markovian effects as exemplified in protein production kinetics through cell division 0.40
Antagonism by the type VI secretion system of Bacteroides fragilis is controlled by a TetR family regulator and released small molecule 1.00
Hierarchical genotype networks and incipient ecological speciation in Qβ phage quasispecies 0.10
Pharmaco-behavioral profiling identifies suppressors of autism gene–associated phenotypes in zebrafish 0.96
Active maintenance of meiosis-specific chromosome structures in Caenorhabditis elegans by the deubiquitinase DUO-1 0.83
Pareto optimality reveals an atlas of cellular archetypes 0.67
Loss of function of the chromatin remodeling gene INO80D leads to neurogenic features of schizophrenia 1.00
N6-methyladenine DNA modification modulates pathogen virulence in nematodes 0.15
The Nemp1–Nesprin complex mediates cellular responses to matrix mechanics 0.79
Stability of epigenetic transgenerational inheritance of adult-onset disease and parturition abnormalities 1.00
Pichia-CLM: A language model–based codon optimization pipeline for Komagataella phaffii 1.00
EPOP and MTF2 activate PRC2 activity through DNA-sequence specificity 1.00
Evolutionary pathways in epistatic mechanical networks 1.00
Origin of class B J-domain proteins involved in amyloid transactions 0.14
ADAR-GPT: A continually fine-tuned language model for predicting A-to-I RNA editing sites 0.30
Cell numbers contribute to cell fate during Ciona cardiopharyngeal mesoderm specification 1.00
O-acyltransferase genes involved in the production of volatile sex pheromones in Caenorhabditis elegans 0.92
Immature Caenorhabditis elegans motor neurons control early embryo behavior via both synaptic and nonsynaptic GABA release 1.00
CHAMP1 complex promotes heterochromatin assembly and reduces replication stress 0.95
Lipid-packing defects are sufficient to modulate membrane insertion and the bound state of α-synuclein 1.00
The variability of evolvability: Properties of dynamic fitness landscapes determine how phenotypic variability evolves 0.80
CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1 0.70
An electron transport complex required in the gut sensitizes Bacteroides to a pore-forming type VI secretion toxin 1.00
The human endogenous retroviral envelope HEMO protein interacts with BACE2: Novel partnership acquired in the primate lineage 0.07
Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion 0.44
S-cone-specific circuitry in the outer plexiform layer of a cone-dominant mammal 1.00
Redox regulation of memory formation by Rrp1 in Drosophila 0.01
Autism-associated Scn2a haploinsufficiency disrupts in vivo dendritic signaling and impairs flexible decision-making 1.00
METTL3-dependent m6A RNA methylation suppresses aberrant mammary epithelial differentiation and neoplastic transformation 0.95
<atl>Reevaluation of whether histones are asymmetrically segregated during asymmetric divisions of stem cells in iDrosophila/i</atl> 0.25
Rewarding touch limits lifespan through neural to intestinal signaling 1.00
HEIP1 orchestrates pro-crossover protein activity during mammalian meiosis 0.33
Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors 1.00
Polycomb Repressive Complex 1 and USP16 localize to the mitochondrion and influence its function 0.92
HISTONE DEACETYLASE-1 is required for epigenome stability in Neurospora crassa 0.44
RNA triple helix assembled by the poly(A) tail enhances retrotransposon mobilization by preventing RNA deadenylation 0.17
Ectopic transcription due to inherited histone methylation may interfere with the ongoing function of differentiated neurons 1.00
Favorable epistasis in ancestral diterpene synthases promoted convergent evolution of a resin acid precursor in conifers 0.50
Emergence of activation or repression in transcriptional control under a fixed molecular context 0.58
Protein-mediated stabilization and nicking of the nontemplate DNA strand dramatically affect R-loop formation in vitro 0.67
Structure of a polymorphic repeat at the CACNA1C schizophrenia locus 1.00
G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes 1.00
Asymmetric development and function of paired sperm-storage organs in Drosophila melanogaster 0.64
TRPC4 regulates limbic behavior and neuronal development by stabilizing dendrite branches through actomyosin-driven integrin activation 0.50
Split-YFP-coupled interaction–dependent TurboID identifies new functions of basal cell polarity in Arabidopsis 1.00
RNA polymerase III transcription–associated polyadenylation promotes the accumulation of noncoding retrotransposons during infection 1.00
Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease 1.00
A preclinical pig model of Angelman syndrome mirrors the early developmental trajectory of the human condition 0.89
Cell-type-informed genotyping of mosaic focal epilepsies reveals cell-autonomous and non-cell-autonomous disease-associated transcriptional programs 0.77
Kinetic mechanisms for the sequence dependence of transcriptional errors 1.00
Macroevolutionary changes in natural selection on codon usage reflect evolution of the tRNA pool across a budding yeast subphylum 1.00
In silico evolution of globular protein folds from random sequences 1.00
Transgenerational epigenetic effect of kings’ aging on offspring’s caste fate mediated by sperm DNA methylation in termites 0.14
Disrupted diencephalon development and neuropeptidergic pathways in zebrafish with autism-risk mutations 1.00
11 8.71
Do distinct subpopulations signify modes of behaviour in a noisy single cell? 1.00
Ocular and extraocular expression of opsins reveals evolutionary trends underlying visual and non-visual functions in bivalves (Pteriomorphia) 0.50
A shoot at the root? Unique development and evolution of the stigmarian apical meristem 1.00
Conserved optical adaptations enable amphibious vision in compound eyes 1.00
Diversification of pre-mating behaviours through temporal reordering of components 0.33
Epigenetic variation can promote adaptation by smoothing rugged fitness landscapes 1.00
Drive, suppression and escape from suppression of a selfish chromosome 1.00
Rewired gene interactions during evolution of the analia and genitalia in Drosophila 0.10
Confounding fuels misinterpretation in human genetics 1.00
Heterogeneous constraint and adaptation across the malaria parasite life cycle 1.00
Autosomally-encoded segregation distortion of sex chromosomes. 0.78
12 8.08
Human DHX29 detects nonoptimal codon usage to regulate mRNA stability 0.05
Multiple chromosomal inversions modulate continuous local adaptation along a steep thermal cline 0.94
Interbreeding between Neanderthals and modern humans was strongly sex biased 1.00
Concurrent L1 retrotransposition events promote reciprocal translocations in human tumorigenesis 0.03
Nutritional specialization and social evolution in woodroaches and termites 0.03
Recurrent acquisition of nuclease-protease pairs in antiviral immunity 1.00
Different repair pathways support intact or truncated insertions by R2 retrotransposon protein 1.00
mRNA initiation and termination are spatially coordinated 1.00
Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity 1.00
Lysosomes signal through the epigenome to regulate longevity across generations 1.00
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae 1.00
Introgression dynamics of sex-linked chromosomal inversions shape the Malawi cichlid radiation 0.03
54 37.13
UBA1-CDK16: A female-specific chimeric RNA emerging through evolution and involved in immune regulation 0.74
Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress 1.00
Hypoxia-responsive interaction between P-TEFb, BHLHE40, and Tim8-Tim13 regulates hypoxic gene transcription 1.00
A thyroid hormone–mediated opsin switch initiates metamorphosis in a proto-vertebrate 1.00
Spontaneous mutation rate and spectrum are modulated by organismal fitness 1.00
Estimating in silico causal effects of DNA methylation on gene expression through genetic anchors in airway epithelium in asthma 1.00
A panoramic view of the expression and function of the Doublesex/DMRT gene family in C. elegans 0.50
Peaceful queen succession in the naked mole rat 1.00
Copper deficiency impairs oligodendrocyte maturation and social behavior via mitophagy and mTOR suppression in ASD 0.05
Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide 0.29
Superabundant microRNAs are transcribed from human rDNA spacer promoters insulated by CTCF 1.00
Enhancing plant antiviral responses and productivity through the elimination of m5C methyltransferase 0.05
Differential SP4 expression and HSP60 abundance in buccal swabs from patients with schizophrenia 1.00
Opposing insulin signals underlie the same developmental switch across hemipteran insects 0.13
Deep-sea fish reveal an alternative developmental trajectory for vertebrate vision 0.25
CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells 1.00
Hybrid female sterility due to cohesin protection errors in mouse oocytes 1.00
Quantitative modulation of a spatial enhancer through the biophysical properties of a transcription factor binding site 0.39
Nat10-mediated ac4C epitranscriptomics orchestrates hematopoietic stem/progenitor cell fate determination via translation control 0.08
Circadian-shaped immune variability predicts infection outcome 1.00
Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD 0.33
CRISPRa-mediated disentanglement of the Dux-MERVL axis in the 2C-like state, totipotency, and cell death 0.31
Direct recruitment of TONSOKU by the N-terminal tails of histone variants H2A.X and H2A.W coordinates DNA repair 0.11
The evolution of cheaper workers facilitated larger societies and accelerated diversification in ants 0.06
Unusual inheritance of a functional cki homolog in the human pathogen Schistosoma mansoni 1.00
BE screen reveals METTL3 S2 dephosphorylation sensitizes gastric cancer cells to oxaliplatin by interfering METTL3-eIF3H interaction 0.06
Conservation of cis-regulatory codes over half a billion years of evolution 1.00
Serine tRNAs compete to regulate the mRNA translation of serine-sensitive codons 1.00
Loss of histone macroH2A1.1 causes kidney abnormalities secondary to a change in nutrient metabolization 0.21
Metabolic regulation of behavior by the intestinal enzyme FMO-2 1.00
Transgenerational adaptation to hypoxia 1.00
Nuclear 2′-O-methylation regulates RNA splicing through its binding protein FUBP1 0.75
Mechanism of USP21 autoinhibition and histone H2AK119 deubiquitination 1.00
Gut epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes 1.00
KMT2D temporally activates neuronal transcriptional factor genes to mediate cerebellar granule cell differentiation 1.00
Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo 1.00
Aplf/Dna2 variants drive chromosomal fission and accelerate speciation in zokors 0.04
Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM 1.00
Reticular thalamic hyperexcitability drives autism spectrum disorder behaviors in the Cntnap2 model of autism 1.00
FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia 0.97
An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility 1.00
Acquisition of neural crest promoted thyroid evolution from chordate endostyle 0.59
AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance 1.00
Histone acetylation readers Bdf1 and Yaf9 direct SWR1 remodeler to +1 nucleosome 1.00
Spinal motor neuron development and metabolism are transcriptionally regulated by nuclear factor IA 1.00
Nonchromatin regulatory functions of the histone variant H2A.B in SWI/SNF genomic deposition 0.22
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology 1.00
A Notch signal required for a morphological novelty in Drosophila has antecedent functions in genital disc eversion 1.00
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage 0.08
Sensing of extracellular l-proline availability by the integrated stress response determines the outcome of cell competition 0.10
H3K79 methylation and H3K36 trimethylation synergistically regulate gene expression in pluripotent stem cells 0.80
<atl>Regulation of MORC-1 is key to the CSR-1–mediated germline gene licensing mechanism in iC. elegans/i</atl> 0.86
Vimentin network dysregulation mediates neurite deficits in SNCA duplication Parkinson’s patient–derived midbrain neurons 0.17
The pioneer transcription factor Zelda controls the exit from regeneration and restoration of patterning in Drosophila 1.00
3 2.03
Modulating alternative splicing of MECP2 is a potential therapeutic strategy for Rett syndrome 1.00
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma 0.03
Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury 1.00
11 3.03
Autoinhibitory feedback preserves intestinal stem cell maintenance and fate commitment 0.20
SLX4IP limits replication stress globally and at ALT telomeres 0.35
A spontaneous termination mechanism of RNA polymerase V shapes the DNA methylation landscape in plants 0.15
A leader-repeat hairpin blocks extraneous CRISPR RNA production in diverse CRISPR-Cas13 systems 0.25
Transcription factor NFYA directs male meiotic entry by regulating accessible chromatin at meiotic promoters in mice 0.13
The mechanism of ribosomal recruitment during translation initiation on the Type 2 encephalomyocarditis virus IRES 1.00
Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2 0.08
CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of maternal-to-zygotic transition in teleosts 0.45
Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization 0.11
The RNA m6A landscape during human oocyte-to-embryo transition. 0.11
Genetic polymorphisms lead to major, locus-specific, variation in piRNA production in mouse 0.20
1 1.00
Infancy IgE methylation score and childhood wheezing and asthma: Multicohort study 1.00
2 1.25
Collective RNAP Dynamics Link Transcriptional Strength to Fidelity 1.00
Fano Factor as the Key Measure of Sensitivity in Biological Networks 0.25
1 1.00
Structure and autoinhibitory regulation of MET1 in the maintenance of plant CG methylation 1.00

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