Immunology articles for Harvard University, United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 182

Article ‘Count’ for Immunology.

Journal Count Share
1 0.00
Universal Nanovial Screening Enables Functional Discovery of Metabolite-Reactive T-Cell Receptors for Cancer Therapy 0.00
1 0.88
Nanodisc-Based Platform for HLA Antibody Identification 0.88
1 0.78
Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming 0.78
1 0.09
DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study 0.09
1 0.29
Diagnostic implications and correlates of plasma ADA2 activity and ADA2 variants 0.29
7 1.17
Plasmin modulates neutrophilic inflammation and alveolar macrophage function, protecting mice from pneumococcal pneumonia 0.04
The C/EBPα-(PU.1-LOUP) regulatory circuit regulates monocyte/macrophage development and immune functions 0.22
Predicting development of pediatric chronic immune thrombocytopenia at disease onset using a statistical risk model 0.07
RGI-2001 for the prophylaxis of acute graft-versus-host disease after allogeneic HCT 0.13
A single dose of a CD137 antibody–drug conjugate protects rhesus macaque allogeneic HCT recipients against acute GVHD 0.63
Phase 1/2 study of high-dose palifermin for GVHD prophylaxis in patients undergoing HLA-matched unrelated donor HCT 0.06
Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study 0.03
2 0.99
Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer 0.76
CCL3 is produced by aged neutrophils across cancers and promotes tumor growth 0.23
3 0.26
ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion 0.07
ZNF296 Drives Immune Evasion in Epithelial Cancers by Repressing Immune Stimulatory Genes. 0.10
Cytotoxic CD8+ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma that Drives Antitumor Immunity. 0.09
5 2.92
In vivo detection of immune responses via cytokine activity labeling 0.25
Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity 0.91
CRATER tumor niches facilitate CD8+ T cell engagement and correspond with immunotherapy success 0.81
Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV 0.32
Structure of gut microbial glycolipid modulates host inflammatory response 0.64
2 1.04
Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis 0.06
An image-based transcriptomics atlas reveals the regional and microbiota-dependent molecular, cellular, and spatial structure of the murine gut 0.98
1 0.71
HEV-Targeted Antibody-Drug Conjugate Promotes Long-Term Cardiac Allograft Acceptance. 0.71
2 0.10
Infections After Kidney Transplantation From Donors With Human Immunodeficiency Virus (HIV) to Recipients With HIV 0.03
IL12RB1 Deficiency Appearing in North America: Expanding the Clinical Phenotypes 0.07
1 0.14
Plasma Soluble Intercellular Adhesion Molecule-1 Has a Central Role in Biomarker Network Analysis and Is Associated With Poor Outcomes in Two Distinct Pediatric Cohorts of Acute Respiratory Distress Syndrome and Acute Respiratory Failure. 0.14
1 0.17
Genetic Polymorphisms in Nuclear Receptors Drive Variations in Responses to Environmental Exposures 0.17
1 0.38
Neutrophil extracellular traps and peptidylarginine deiminase 4–mediated inflammasome activation link diabetes to cardiorenal injury and heart failure 0.38
1 0.81
Loss of the tumor suppressor PTEN activates cell-intrinsic interferon signaling to drive immune resistance 0.81
12 3.42
Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging 1.00
Interleukin-4-producing type 2 innate lymphoid cells in the lymph node promote proallergic Tfh13 cell differentiation 0.36
Commensal-myeloid crosstalk in neonatal skin regulates interleukin-1 signaling and cutaneous type 17 inflammation 0.01
Scalable TCR synthesis and screening enable antigen reactivity mapping in vitiligo 0.25
Sequential class switching generates antigen-specific gut IgA from IgG1 B cells 0.11
FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry 0.00
Myeloid cells mediate interferon-driven resistance to immunotherapy in advanced renal cell carcinoma 0.58
The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells 0.00
Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity 0.00
DOCK8 in T cells promotes Th17 and Treg cell functionality to restrain mucosal mast cells and limit susceptibility to oral anaphylaxis 0.62
A conserved immune dysregulation signature is associated with infection severity, risk factors prior to infection, and treatment response 0.00
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction 0.48
1 1.00
Early-life exposure to ambient temperature and polycystic ovary syndrome: a nationwide cohort study 1.00
1 0.10
Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment 0.10
2 1.09
Stress-induced glucocorticoid signaling impairs enteric neurotrophin BDNF–TrkB pathway and drives gastrointestinal dysmotility 0.63
Identification and characterization of nanobodies specific for the human ubiquitin–like ISG15 protein 0.47
2 0.77
The BIOPREVENT machine-learning algorithm predicts chronic graft-versus-host disease and mortality risk using posttransplant biomarkers 0.14
Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9 0.62
2 0.77
Randomized, Placebo-Controlled Trial of B-Cell Depletion for Prevention of Corticosteroid-Requiring Chronic Graft-Versus-Host Disease. 0.74
Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation. 0.03
6 1.11
Blimp-1 integrates alarmin signals in ILC2s and drives proinflammatory functions required for type 2 immunity 0.00
A PI3Kδ-Foxo1-FasL signaling amplification loop rewires CD4+ T cell signaling and differentiation 0.01
DOCK8 and STAT3 cooperate to restrain IgE-inducing T follicular helper cells 0.16
Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation 0.77
S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum 0.05
Noncanonical T cell responses are associated with protection from tuberculosis in mice and humans 0.12
4 0.61
Allograft Rejection and the Latent HIV Reservoir in Kidney Transplant Recipients with HIV 0.03
Impact of COVID-19 Monoclonal Antibody Therapy on Subsequent Vaccine-Elicited SARS-CoV-2 Immune Responses 0.15
A Test-Negative Design for Immune Correlates Approximates a Traditional Exposure Proximal Design but Requires Far Fewer Blood Samples 0.06
National- and state-level SARS-CoV-2 immunity trends from January 2020 to December 2023: a mathematical modeling analysis 0.38
1 0.03
Switching between Janus kinase inhibitors for treatment of alopecia areata: A Multi-Center Retrospective Review 0.03
3 1.88
Mechanistic insights from transcript analysis of long-term pig to non-human primate kidney xenografts 1.00
Single-cell spatial transcriptomics reveal intraglomerular cell activation and ligand-receptor relationships in chronic, active antibody mediated rejection 0.78
A systematic literature review and meta-analysis evaluated modifiable risk factors for the development of BK polyoma virus-associated complications 0.10
11 1.87
Linear RAG scanning mediates editing of Igκ variable region repertoires 1.00
Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity 0.02
Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion 0.06
Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist 0.00
Neuro-epithelial circuits promote sensory convergence and intestinal immunity 0.05
Erythropoietin receptor on cDC1s dictates immune tolerance 0.00
iHALT unlocks liver functionality as a surrogate secondary lymphoid organ 0.17
Multi-omics analysis of a pig-to-human decedent kidney xenotransplant 0.01
Physiology and immunology of pig-to-human decedent kidney xenotransplant 0.01
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours 0.09
WSTF nuclear autophagy regulates chronic but not acute inflammation 0.47
1 0.62
A druggable redox switch on SHP1 controls macrophage inflammation 0.62
26 10.46
Whole-protein screening and multi-modal profiling of antigen-specific CD4+ T cells at single-cell resolution 0.01
Efficacy and durability of immediate versus delayed single-dose HPV vaccination for persistent infection among young women in Kenya: a randomized, blinded, cross-over clinical trial 0.17
PTPN2 inhibition unleashes response to STING agonism in head and neck squamous cell cancer 0.94
In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer 0.82
Tim-3 agonist restrains ILC2 function and attenuates airway hyperreactivity via NLK pathway 0.10
Tuft cells shape airway remodeling by eliciting OXGR1- and SOX9-dependent stem cell programs 1.00
TYK2 mediates neuroinflammation in Alzheimer’s disease brains with TDP-43 pathology 0.84
A conserved, immune-regulated peritrophin promotes Vibrio cholerae colonization of the arthropod intestine 1.00
CD8 T cell loss induces autoinflammation in inborn errors of cell death 0.03
STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways 0.02
Negative feedback regulation of STING signaling by TAX1BP1-directed Golgiphagy 0.05
Intelectin-2 is a broad-spectrum antimicrobial lectin 0.13
Sideways lipid presentation by the antigen-presenting molecule CD1c 0.17
The resting and ligand-bound states of the membrane-embedded human T-cell receptor–CD3 complex 0.01
Discovery of a small molecule TLR3 agonist adjuvant 0.93
Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity 0.02
A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice 0.80
Specification curve analysis of the TEDDY study reveals large variation in microbiome-based T1D predictive performance 0.76
APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signaling 0.07
Selective HLA knockdown and PD-L1 expression prevent allogeneic CAR-NK cell rejection and enhance safety and anti-tumor responses in xenograft mice 0.59
Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV 0.00
Physiologic Homeostasis in a Living Human after Pig Kidney Xenotransplantation 0.83
A citrullinated histone H3 monoclonal antibody for immune modulation in sepsis 0.04
Urinary Complement proteome strongly linked to diabetic kidney disease progression 0.57
Intestinal CD4−CD8αβ−TCRαβ+ T cells function as tolerogenic antigen presenting cells in mice 0.08
Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro 0.46
1 0.10
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation 0.10
18 4.90
A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines 0.49
HLA class I signal peptide variation predicts strength of NKG2A NK cell response to missing-self and risk of human disease 0.09
The immunometabolic topography of cellular organization and bacterial control in tuberculosis granulomas 0.04
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function 0.07
Stability and progressive differentiation of TFR cells are intrinsically and extrinsically controlled by TFH programs 0.70
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors 0.05
Tissue-resident exhausted and memory CD8 T cells have distinct ontogeny, function and roles in disease 0.01
DC subsets and states unraveled across human juxtatumoral and malignant tissues 0.02
Interferon-mediated NK cell activation increases cytolytic activity against T follicular helper cells and limits antibody response to SARS-CoV-2 0.11
Thrombospondin-1–CD47 signaling contributes to the development of T cell exhaustion in cancer 0.02
Peanut allergy oral immunotherapy drives single-cell multi-omic changes in peanut-reactive T cells associated with sustained unresponsiveness 0.03
The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells 0.12
Transient tissue residency and lymphatic egress define human CD56 NK cell homeostasis 0.04
Spatial and functional diversity of innate lymphoid cells in the human female genital tract may contribute to antiviral responses to HIV 0.04
Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesis 0.93
A STUB1–CHIC2 complex inhibits CD8+ T cells to restrain tumor immunity 0.94
PD-1 is requisite for skin TRM cell formation and specification by TGFβ 0.37
IL-4 impairs the formation of skin-resident memory CD8 T cells 0.86
5 1.05
Linavonkibart and pembrolizumab in immune checkpoint blockade-resistant advanced solid tumors: a phase 1 trial 0.10
Interpretable inflammation landscape of circulating immune cells 0.08
Immune profiling in a living human recipient of a gene-edited pig kidney 0.69
Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma 0.10
Anti-sporozoite monoclonal antibody for malaria prevention: secondary efficacy outcome of a phase 2 randomized trial 0.08
1 0.25
IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin 0.25
25 7.80
Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation 0.18
Selective depletion of virus-specific CD8 T cells from the liver after PD-1 therapy with Fc-intact antibody during chronic infection 0.13
Deep learning–enabled scaffolding of spatial arrays of PfCSP epitopes 0.01
Phage display–mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila 1.00
Tim-3-targeted vaccines overcome tumor immunosuppression and reduce cDC1 dependence to elicit potent anti-tumor immunity 0.01
Extracellular heme:DNA complexes promote oxidative stress and inflammation during lupus-associated hemolysis 0.68
Regulatory T cells safeguard liver health during metabolic-associated steatohepatitis 0.86
Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease 0.11
Shigella OspF blocks rapid p38-dependent priming of the NAIP–NLRC4 inflammasome 0.29
IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis 0.06
Rroid2 regulates effector-to-memory CD8+ T cell differentiation during infection in vivo 0.07
Modulation of the PGRMC1/NLRP7/HLA-C axis by autophagy is linked to both spontaneous preterm birth and gestational choriocarcinoma 0.08
Dynamics and variegation in the Treg response to Interleukin-2 0.72
High-throughput screening for class I peptide MHC binding via yeast surface display 0.13
Restoration of cGAS in cancer cells promotes antitumor immunity via transfer of cancer cell–generated cGAMP 0.81
Local control of T cell fate in lymph nodes safely and durably reverses myelin-driven autoimmunity 0.07
Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation 0.69
Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow 0.04
Synovial MS4A4A correlates with inflammation and counteracts response to corticosteroids in arthritis 0.02
Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state 0.05
Seeding of visceral adipose tissue with perinatally generated regulatory T cells shapes the metabolic tenor in mice 1.00
Macrophage TBK1 signaling drives the development and outgrowth of breast cancer brain metastasis 0.18
ER-resident CCDC134 safeguards TLR4 maturation by maintaining gp96 stability 0.13
Elucidating the role of Campylobacter concisus–derived indole metabolites in gut inflammation and immune modulation 0.42
BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza 0.06
5 1.71
Disordered protein LAT encodes relative levels of signaling pathways in T cell activation 0.24
Sialylated CD43 forms a glyco-immune barrier that restrains antileukemic immunity 0.66
Overcoming T cell tolerance to tumor self-antigens through catch-bond engineering 0.00
Intestinal mast cell–derived leukotrienes mediate the anaphylactic response to ingested antigens 0.08
Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense 0.73
6 1.44
Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center 0.56
Droplet-based single-cell pairing for high-throughput interaction mapping of antigen-receptor combinations 0.07
Conserved CD8 T cell vaccines without B cell epitopes drive robust protection against SARS-CoV-2 that is enhanced by intranasal boost 0.58
Acoustofluidic system for targeted antibody removal in transplantation: Enabling small-volume therapeutic apheresis 0.01
IgM and IgG1 B cell receptors differentially affect B cell fates and dictate the pathogenesis of mature B cell lymphomas 0.09
Origin of immunoglobulins and T cell receptors: A candidate gene for invasion by the RAG transposon 0.13
3 1.57
Phase 1 and preclinical studies reveal safety, pharmacokinetics, and efficacy of intranasal delivery of the influenza antibody CR9114 0.26
Germline-encoded recognition of peanut underlies development of convergent antibodies in humans 0.31
IFN-γ–resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models 1.00
1 0.10
Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells 0.10
6 3.39
Heterozygous variants in DOCK2 leading to susceptibility to viral illnesses 0.83
A clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases 0.71
Interactions between host genetics and gut microbiome influence susceptibility to childhood asthma and lung function 0.80
Prevalence of KIT D816V in anaphylaxis or systemic mast cell activation 0.04
Effect of Dupilumab on Small Airways Measured by Airway Oscillometry in VESTIGE 0.11
T cell and autoantibody profiling for primary immune regulatory disorders 0.89
8 0.73
Immunogenicity and Safety of vYF, a Yellow Fever Vaccine — A Phase 2 Trial 0.02
A Phase 2 Randomized Trial of Mezagitamab in Primary Immune Thrombocytopenia 0.08
Romiplostim versus Placebo for Chemotherapy-Induced Thrombocytopenia 0.15
Ianalumab plus Eltrombopag in Immune Thrombocytopenia 0.04
Engasertib versus Placebo for Bleeding in Hereditary Hemorrhagic Telangiectasia 0.12
Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 0.23
Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency 0.03
RSV Prefusion F Vaccine for Prevention of Hospitalization in Older Adults 0.06

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