Medical Biotechnology articles for China

Time frame: 1 May 2025 - 30 April 2026

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Count: 1061

Article ‘Count’ for Medical Biotechnology.

Journal Count Share
93 89.67
Modular Functionalized Gates for Field-Effect Transistor Biosensors Enabling Reliable Detection of Trace miRNAs 1.00
Self-Assembling Enveloped Virus-Mimicking Particle for Extrahepatic Targeting mRNA Delivery 1.00
A Hybrid Phospholipid Monolayer-Based Interface for Interaction-Enhanced Electrical Detection in Biofluids 0.90
Direct Activation of Follicular Melanocytes by Polymeric Tyrosinase Nanocapsules for Reversing Hair Graying 1.00
Ultrasound-Controlled Nano-Oxygen Delivery Modulates Endothelial Cells to Enhance Tumor Perfusion 1.00
Developing Inner Ear Organoids in Ultrasound-Activated Piezoelectric Hydrogel for Assessing Ototoxicity 1.00
A Strand-Displacement Enabled DNA Nanomachine for Targeted St6Gal1 Silencing and Immune Reprogramming in Melanoma 1.00
Triple-Cascade Responsive Pneumatic Nanomotor Enhance Cancer Immunotherapy by Oncolytic Virus-Triggered Pyroptosis 1.00
Aptamer-Driven DNA Framework Switches for Clearing Programmed Cell Death-Ligand 1 Positive Extracellular Vesicles via Macrophage Recruitment 1.00
Mucosal-Penetrating Nanovaccine Enhances Mucosal and Systemic Immunity against Respiratory Syncytial Virus Infection 1.00
Bioorthogonal Click-Engineered Microneedle Patch Enables Adeno-Associated Virus-Mediated Dermal Acidic Fibroblast Growth Factor Expression for Hair Loss Treatment 1.00
Fingerprinting Fluorescent In Situ Hybridization Enables Multiplexed Identification of Pathogenic Bacteria 1.00
Tailored Extracellular Matrix-Biomimetic Coating Favors Tissue Healing by Modulating the Microenvironment 1.00
Gravity-Driven Formation of Water-in-Wax Spheres for Efficient One-Pot CRISPR Diagnostics 1.00
Multi-Activity Nanozyme-Integrated Scaffolds: Harnessing Synergistic Enzyme-like Effects for Complete Treatment of Infected Bone Defects 1.00
A Dual-Hue Recognizable Lateral Flow Immunoassay Corresponding to Distinct Sensitivity Ranges for Timely and Quantitative Diagnosis of Prostate Cancer 1.00
Priming the Liver Endocytic Pathway to Accelerate Hepatobiliary Clearance of Nanoparticles 1.00
Reactive Oxygen Species-Activatable Topological Transition Nanogel Integrated with cfDNA Degradation Function for Adaptive Barrier Repair in Inflammatory Bowel Disease 1.00
Caveolar Endocytosis Governs Nanoneedle Transfection 0.13
Dissolution-Mediated Synthesis of Atomically Thin High-Entropy Hydroxides for Efficient Polyester Glycolysis 1.00
Ultrasound-Triggered Charge-Reversal Nanoparticles via Golgi-Dependent Iterative Transcytosis for Enhanced Deep Tumor Penetration 1.00
A Dual-Fusogenic Virus-like Vector Enables Direct Cytosolic Delivery of mRNA Vaccines to Dendritic Cells 0.94
Piezoelectric Nanofibers Synchronize Mitochondrial Dynamics and Immune Responses for Regeneration of Infected Wounds 1.00
Self-Carrier Nanoagonist Enabling Positive Feedback Regulation of Cuproptosis-Immunity for Potent Antitumor Therapy 1.00
Phosphorothioate and 2′-Fluoro Ribose Substitution-Mediated Hydrophobic Effect Empowers RNA Probes for Highly Sensitive and Subtype-Selective miRNA Imaging 1.00
Self-Powered Gravity Domino Microfluidics for Rapid At-Home Immunoassays with Artificial Intelligence 1.00
Bone-Targeted Multifunctional Nanoplatform Combining Osteoimmunoregulation and Mild Photothermal Effect to Promote Fracture Repair 1.00
Bioinspired Reconstruction of Polysaccharide Nanofibers Driven by Shear and Cavitation in High-Pressure Microfluidics 0.56
Redox-Responsive Peptide Coacervates for Enhanced mRNA Delivery and Intracellular Release 1.00
Shape-Dependent Entropic Forces Govern Synergistic Bystander Nanoparticle Uptake 0.89
Exosome-Infused DTM-MPs Hydrogel Scaffold: A Smart Platform for Tendon Repair with Sustained Bioactivity and Anti-Inflammatory Benefits 1.00
Engineering of Metal–Organic Networks as Band-Aid for the Repair of Osteoporotic Bone Fractures 1.00
Bioinspired Face Mask for Exhaled Breath Condensate Collection and Multiplexed Biomarkers Analysis 1.00
Bioactive Multifunctional Hydrogel Scaffolds Remodel the Inflammatory Microenvironment and Osteogenic-Osteoclastic Homeostasis to Advance Osteoporotic Bone Defect Repair 1.00
Bioinspired miRNA-Responsive Ca2+ Nanoregulator with Dual Interference Pathways and Self-Amplifying Cascade for Tumor-Targeted Mitochondrial Dysfunction 1.00
Dual-Functional Nanotherapy-Reinforced Hydrogel for Synergistic Antimicrobial and Immunomodulatory Oral Tissue Repair 1.00
Reactive Oxygen Species-Responsive Glycocalyx-Mimetic Hydrogel-Engineered Bioprosthetic Valves with Integrated Anticoagulant, Anti-Inflammatory, and Endothelialization Properties 1.00
All-in-One Nanounit Embedded with Biomimetic Peptide for Comprehensive Caries Repair 1.00
Tumor-Specific Delivery of Nanomedicines via a Nutrient Sensing-Driven Pathway Mediated by Niemann-Pick C1-Like 1 1.00
Spatial Lipid Metabolic Remodeling from Placenta to Multiple Suborgans during the Gestational Micro- or Nanoplastics Exposure 1.00
Osteoinductive and Piezoelectrically Malleable Nanocomposite Bone Graft 0.79
Nanopeptides-Loaded Electro-Assembled Oriented Collagen Matrix for the Synergistically Promotes Early Angiogenesis in Tendon Healing 1.00
A Tumor Microenvironment-Responsive Self-Oxygenating Nanoplatform for Dual-Enhanced Cuproptosis and Sonodynamic Synergistic Immunotherapy 0.86
Induced Pluripotent Stem Cell-Derived Extracellular Vesicles Prevent Neural Stem Cell Senescence to Promote Cognitive Recovery after Traumatic Brain Injury 1.00
Multiplex Nanopore Detection of Structurally Diverse Per- and Polyfluoroalkyl Substances in Surface Water 1.00
Orbital Hybridized MoO3/MoSe2 Heterojunction for Dual-Driven Interfacial Reaction and Charge Transfer Toward Enhanced Electrochemical Response 1.00
Flower-Shaped Lipid Nanoparticles Evade Apolipoprotein E-Mediated Liver Tropism for Safe and Enhanced Cytokine-Based Cancer Immunotherapy 1.00
Disulfide-Appended siRNA Nanoeyedrops: Noninvasive Gene Therapy for Targeting Retinal Angiogenesis 1.00
Mass-Ratio-Controlled Organ-Selective Phosphatidyl Polymer Carrier for In Vivo Targeted mRNA Delivery 1.00
Intelligent Responsive Zeolitic Imidazolate Framework-8@Copper Oxide Nanocomposite 3D-Printed Scaffolds for Efficient Repair of Infected Bone Defects 1.00
Fenton Reaction-Mediated Endolysosomal Disruption for Efficient Cytosolic Protein Delivery 1.00
Common Divalent Cations Elicit Sublethal Effects of Negatively Charged Nanoplastics on Shewanella oneidensis by Compromising Membrane Protein Functionality 0.89
Mesenchymal Stem Cell-Derived Extracellular Vesicles Ameliorate Temporomandibular Joint Osteoarthritis by Suppressing Osteoclast Activity Via let-7a-5p/Integrin β3 Axis 1.00
Bioinspired Ultrastable Cu(I)-Bovine Serum Albumin Single-Atom Nanozymes Enable MRI-Trackable Synergistic Catalytic Therapy and Cuproptosis for Tumors 1.00
Nanobiocatalyst-Driven Spatiotemporal Hydrogen Delivery Induces Dormancy Potentiated Catalytic Tumor Therapy 1.00
Directional Biomimetic Scaffold-Mediated Cell Migration and Pathological Microenvironment Regulation Accelerate Diabetic Bone Defect Repair 1.00
An Aggrecanase-Responsive Delivery Hydrogel System of miRNA-17 Facilitates Microfracture-Mediated Articular Cartilage Regeneration by Reprogramming Hostile Inflammatory Niche 1.00
ZnCe-LDO Nanozyme-Based Multifunctional Hydrogel Promotes Bone Regeneration by Inflammatory Macrophage Reprogramming and Piezo1 Activation 1.00
Effective RNA Delivery with Aggregation-Induced Lipid Backfolding 1.00
M-Sec Overexpressed Stem Cells Growing Abundant Tunneling Nanotubes for Diverse Active Transferring 1.00
Ordered DNA-Wrapped Single-Chirality Carbon Nanotubes Enable an Unparalleled Sensing Platform for Copper Ion Detection 1.00
An Immunomodulating Regenerating Hydrogel That Rescues the Oxidative Microenvironment and Reverses Cell Senescence for Osteoporotic Bone Defects 0.87
Polyethylene and Polyvinyl Chloride Nanoplastics in Human Follicular Fluid and Seminal Plasma: Impact on Fertilization and Sperm Quality 1.00
Establishment of a Cochlear Organoid Platform for Remodeling the Extracellular Matrix 1.00
Deep Learning-Enhanced Hand-Driven Spatial Encoding Microfluidics for Multiplexed Molecular Testing at Home 1.00
Electrically Driven Chimeric Extracellular Vesicles Crossing the Fundus Barrier for Retinoblastoma Treatment 1.00
Wide Dynamic Range Multiplex Digital Clustered Regularly Interspaced Short Palindromic Repeat Chip for Rapid Detection and Absolute Quantification of Nucleic Acids 1.00
High-Performance Graphdiyne Oxide/Au Nanoparticle Electrode for Electrochemical Non-enzymatic Glucose Sensor 1.00
Reversible Adhesive Hydrogel Balancing Conflicting Needs of Strong Adhesion and Painless Removal for Diabetic Joint Wound Healing 1.00
Mechanically Matched Heart-on-a-Chip Platform Mediated Maturation of Excitation–Contraction Coupling 0.83
Bioinert Albumin Surface Enables Ultra-High Vascular Cell Selectivity Superior to Specific Binding Ligands 1.00
Mitochondria-Targeted Microneedles Reverse Doxorubicin Resistance via Apoptosis-Ferroptosis Synergy 1.00
Injectable Thymosin β4-Modified Hyaluronic Acid Hydrogel with Exosomes for Stem Cell Homing and Neuronic–Angiogenic–Osteogenic Coupled Cranial Repair 1.00
Flexible Mechanoporation Chips for High-Throughput Intracellular Delivery Based on Controlled Pneumatic Microvalve Array 1.00
Three-Dimensional Bioprinted Scaffolds Loaded with Multifunctional Magnesium-Based Metal–Organic Frameworks Improve the Senescence Microenvironment Prompting Aged Bone Defect Repair 1.00
Virus-like Nanoparticles Deliver Small Interfering RNA to Pancreatic Cancer Cells through Filopodia-Mediated Internalization 1.00
Adipose-Derived Stem-Cell-Derived Exosomes Encapsulated Patch for Modulating Inflammation and Promoting Tissue Regeneration 0.90
Differential Mapping of Intracellular Metallic Nanoparticles and Ions and Dynamic Modeling Prediction 0.73
Living Microecological Microneedle Patches Enable Proregenerative Microenvironmental Remodeling for Promoting Infected Diabetic Wound Healing 1.00
Astragalus Polysaccharide Hydrogels with Drug-Carrying Super Self-Assembly from Natural Herbs Promote Wound Healing 1.00
Lab on Pipette: Robust Biochemical Sensing with Functional Laser-Induced Graphene Electrode Array for On-Site and Disposable Urine Analysis 1.00
Iterative Screening of Vitamin E-Based Functional Lipid Nanoparticles for mRNA Delivery 1.00
Deciphering the Distinct Roles of Molecular and Supramolecular Chirality in Osteogenic Differentiation of Mesenchymal Stem Cells in 3D Hydrogels 1.00
Enhanced Nano-Vaccine Utilizing Biomineralized Virus-like Particles for Efficient Glioblastoma Immunotherapy via the Nose-To-Brain Delivery Pathway 1.00
A Generative Artificial Intelligence Copilot for Biomedical Nanoengineering 0.40
Tamibarotene-Loaded Nanoemulsion Incorporating Toll-like Receptor 2/6 Agonist as an Intramuscular Adjuvant System Enhances Gastrointestinal Mucosal Immunity 1.00
Trehalose Acts as a Mediator: Imbalance in Brain Proteostasis Induced by Polystyrene Nanoplastics via Gut Microbiota Dysbiosis during Early Life 1.00
Discrimination of Respiratory Tract Infections by a Reduced Graphene Oxide Array Modified with Metal−Organic Frameworks and Metal Phthalocyanines 1.00
Ultrastiff Bioinspired Protein–Carbon Nanotube Hybrid Sponge with Shape Memory Effects 1.00
Ultrasound-Driven Selenium Nanoparticles Realize Bone Defect Repair through Activating Selenoproteins to Regulate PI3K/AKT Signaling Pathway 1.00
Remodeling the Senescent Microenvironment for Promoting Osteoporotic Tendon-to-Bone Healing via Synergizing Senolytic Quercetin and Aligned Nanowire-Structured Hydrogels 1.00
Mechanism of S-Palmitoylation in Polystyrene Nanoplastics-Induced Macrophage Cuproptosis Contributing to Emphysema through Alveolar Epithelial Cell Pyroptosis 1.00
A Gold Nanoparticles and MXene Nanocomposite Based Electrochemical Sensor for Point-of-Care Monitoring of Serum Biomarkers 1.00
72 69.22
Supramolecular dynamic hydrogels loaded with bevacizumab nanoparticles promote hyaline cartilage regeneration by inhibiting angiogenesis 1.00
Carrier-Free Spherical Nucleic Acids Engineered by Coordination-Competition for Programmable Release and Cancer Immunotherapy 1.00
A Nitric Oxide-Releasing Zwitterionic Glycocalyx-Mimetic Hydrogel Armored Bioprosthetic Valve with Integrated Antithrombotic, Endothelialization-Promoting, and Immunomodulatory Capacities 1.00
Multifunctional bioactive peptide-laden and adhesion-switchable dual-crosslinked hydrogel for accelerated healing of infected deep burn wounds 1.00
In vivo self-assembled DNA vaccine elicits efficient immune protection against viral myocarditis by targeting draining lymph nodes 1.00
Preparation of nanofibrous membrane-covered saccule gastric tubes and their treatment of radiation esophagitis 0.70
Kinetic negative-feedback-based barrier membrane attenuates pathological fluctuations and promotes bone regeneration in diabetes 1.00
A pH-responsive hyaluronic acid hydrogel facilitates lesion-localized integrin α5β1 agonism to attenuate osteopontin signaling and fibrosis in intrauterine adhesions 0.78
Dual Crosslinked Thermosensitive Hydrogel Engineered with Multiple Dynamic Hydrogen Bonds for Enhanced Photodynamic Antibacterial Activity and Wound Healing 1.00
Chemical Modifications of RNA Influence the Micellar Assembly Stability and Intracellular Distribution of Polycation/RNA Complexes 1.00
PFSSTKT(PFS)-functionalized Hierarchical Porous ECM Scaffolds Facilitate Articular Cartilage Regeneration through the Recruitment of Endogenous Stem Cells and Chondrogenic Induction 1.00
A scaffold-free, collagen-guided self-assembling adipose construct for functional soft tissue reconstruction 1.00
Ultrasound-mediated blockade of nociceptive transmission by targeted liposomes for efficient cancer pain therapy 1.00
Mitochondrial transfer through tunneling nanotubes inspires an innovative strategy for intercellular drug delivery 1.00
Sulfide-based, Pro-regenerative, Anti-inflammatory Vascular Grafts: Impregnation of Slow-released Sulfide Signals into Graft Implants 0.07
Helix-Guarded Molecular Clips Confer Robust Scavenging of Intra-Articular Cell-Free DNA for the Treatment of Rheumatoid Arthritis 1.00
Mechanically Responsive Yes-associated protein-Inhibiting Peptide Hydrogel for Scarless Wound Healing 1.00
A bioorthogonal click reaction-based platelet-rich plasma delivery system for accelerating wound healing 1.00
Fabrication and in vitro evaluation of a high-strength, flexible, and bioresorbable warp-knitted silk patch for tendon tissue repair 1.00
Self-Adaptive 3D-Printed PCLA/BCP Scaffolds Functionalized using Vapor Etching and Nanocoating for Immunomodulatory and Antibacterial Bone Regeneration 1.00
Learning mechanical inhomogeneity of keloid scars in vivo with shear wave elastography based on physics-informed neural networks 1.00
Hydrogen enhanced photothermal therapy for redox-regulated tumor apoptosis and immune reprogramming 1.00
Near Infrared Excitation of an Upconversion Nanoparticle@TiO2-Nitrate System to Generate Nitrate Radicals for Deep Tissue Penetration in Tumor Catalytic Therapy 1.00
Inflammation-Responsive Biodegradable Nanocomposite Hydrogels for Enhanced Metalloimmunotherapy in Chronic Periodontitis 0.93
Injectable, Antifouling Granular Zwitterionic Hydrogels for Preventing Postoperative Intrauterine Adhesion and Restoring Fertility 1.00
In situ pro-regenerative and repair capabilities of human umbilical mesenchymal stem cells and collagen hydrogel complex in mice with thin endometrium 1.00
Copper-Manganese Bimetallic Oxide-Encapsulated Hydrogels with Multienzyme Activities Accelerate MRSA-Infected Wound Healing by Disrupting Bacterial Protein Expression 1.00
Dual-functional bioinspired nanospray for accelerated wound healing: Visible light-activated bismuth composites 1.00
Electrosprayed hydrogel microsphere dressing promotes vascularization and accelerates wound healing 0.92
One-step Solid phase Reaction-Induced Hydroxyapatite/Magnesian Whitlockite Bioceramics for Enhanced Bone Regeneration 1.00
The Clinic-in-a-Dressing Paradigm: Synchronized Diagnosis and Treatment in Chronic Wounds via Hydrogel-Nanofiber Matrices 0.96
Autologous platelet-rich plasma dual-network hydrogel promotes human endometrial regeneration 1.00
A viral infection-biomimetic strategy for Antibody-Guided Targeted Protein Degradation 1.00
Endothelial function-biomimetic hydrogel-surface engineered non-glutaraldehyde bioprosthetic valve with antithrombotic, immunomodulatory and pro-endothelialization performance 1.00
Characterization of Stability and Shell Elasticity of Monodisperse Microbubbles with Different Pegylated-lipid Content using Pressure-Dependent Attenuation Spectra 0.75
The Mo-14Re alloy, a promising candidate material for bioresorbable vascular scaffolds 1.00
M2 macrophage-laden vascular grafts orchestrate the optimization of the inflammatory microenvironment for abdominal aorta regeneration 1.00
Structural and Mechanical Properties of Engineered Silkworm-Spider Composite Silk 1.00
Bilayer vascular grafts incorporated with S-nitrosated keratin nanoparticles and resveratrol to enhance long-term nitric oxide release and endothelialization 1.00
A costal-cartilage derived stem cell-laden prominin-1-derived peptide collagen hydrogel for angiogenesis and bone regeneration 0.83
Biomimetic self-gelling and adhesive powder for seamless sealing and neural regeneration after brain injury 1.00
A hydrated fibrous gene patch codelivers TGF-β1 siRNA/TAT and berberine for the treatment of peritendinous antiadhesion 1.00
A Tumor Microenvironment-responsive Nanocomposite for Enhanced Copper Retention and Hypoxia Reversal to Promote Cuproptosis in Tumor Treatment 1.00
Deciphering the heterogeneity of calcified structure in different entheses via high-resolution characterization techniques 1.00
Spatiotemporal self-reinforcing hydrogel spray with antibacterial and anti-inflammatory properties for accelerated diabetic wound healing 1.00
Anti-inflammatory itaconate-loaded, cell-adhesive peptide-conjugated artificial small diameter vascular grafts for blood vessel regeneration 1.00
Mechanically-adaptive Janus hydrogel enhances scarless tendon healing with tissue-adhesion prevention 1.00
NIR-II responsive copper-nitrogen doped photocatalysts for pyroptosis and cuproptosis 1.00
Nano-carriers mediate reciprocally chained promotion between ROS and mitochondrial calcium overload for enhanced antitumor therapy 1.00
Microenvironment-responsive recombinant collagen XVII-based composite microneedles for the treatment of androgenetic alopecia 1.00
Poly(ethylene glycol)-norbornene-heparin-piposome composite hydrogels for in situ spraying and ultra-fast adhesion: meeting the challenges of endothelial repair of vascular injury 0.96
A biomimetic nanofiber composite hydrogel with tissue adhesion, self-healing and antibacterial ability for infected wound healing 1.00
An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment 0.92
Delivery of siGPX4 through a thiol-mediated pathway using a fluorinated cell-penetrating poly(disulfide) for inducing ferroptosis in breast cancer 1.00
Coaxial printing of slow-release heparin-binding epidermal growth factor scaffold to avoid the occurrence of intrauterine adhesions 1.00
Engineering of bioprosthetic heart valves with synergistic zwitterionic surface modification and zirconium cross-linking for improved biocompatibility and durability 1.00
Biodegradable Zn-xY alloys with enhanced osteogenesis and angiogenesis effects for bone implant applications 1.00
Flexible beam-based microelectrode arrays integrated with oriented nanofiber scaffolds for electrophysiological monitoring of cardiac tissue 1.00
Improving tendon repair through spatiotemporal modulation of TGF-β1 expression using an ultrasound-responsive hydrogel carrying siRNA-loaded nanoparticles 1.00
A dissolvable microneedle platform for the delivery of tumor-derived total RNA nanovaccines for enhanced tumor immunotherapy 1.00
Biodegradable Zn-Li-Mn alloy to achieve optimal strength and ductility for bone implants 1.00
Catechol crosslinked bioprosthetic valves derived from caffeic acid and dopamine-conjugated porcine pericardia exhibit enhanced antithrombotic, immunomodulatory and anticalcification performance 1.00
Programmed drug delivering Janus hydrogel adapted to the spatio-temporal therapeutic window for Achilles tendon repair 1.00
Natural regeneration-inspired sequential delivery of synergistic growth factors for structural and functional endometrial regeneration 1.00
Vascular grafts with a mimetic microenvironment extracted from extracellular matrix of adipocytes can promote endothelialization in vivo 1.00
A self-powered casein hydrogel E-dressing with synergistic photothermal therapy, electrical stimulation, and antibacterial effects for chronic wound management 1.00
Boosting the angiogenesis potential of self-assembled mesenchymal stem cell spheroids by size mediated physiological hypoxia for vascularized pulp regeneration 1.00
Pollen-like mesoporous silica nanoparticles facilitate macrophage-mediated anti-inflammatory response via physical contact cues in the osteoimmune microenvironment 0.70
Nucleus pulposus cell-mimicking nanoparticles for cell-specific HIF1A editing to modulate SASP-mediated disc inflammation via autophagy activation 1.00
CXCR4-targeted ultrasound microbubbles for imaging and enhanced chemotherapy/Immunotherapy in liver cancer 1.00
Osteogenic surgical sutures for tendon traction and fixation: A model of achilles tendon sleeve avulsion 0.77
Construction of anti-calcification small-diameter vascular grafts using decellularized extracellular matrix/poly (L-lactide-co-ε-caprolactone) and baicalin-cathepsin S inhibitor 0.93
104 99.87
Bioresorbable Piezo-Triboelectric Patch Enabled Bioelectric Stimulation for Accelerated Wound Healing 1.00
Synergistic Piezoelectricity and Lubrication in an Injectable Hydrogel for Osteochondral Regeneration 1.00
Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma 0.93
Multi-Responsive Dendrimer-Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy 0.50
Microenvironment-Responsive Nanozyme for all Stages of Infectious Chronic Wound Management through Macrophage Reprogramming 1.00
Novel Flexible Wearable Field-Effect Transistor Aptasensor with DNA Hydrogel for In Situ Wireless Detection of Organophosphorus Pesticide Residues 1.00
Framework Nucleic Acid Nanoparticles Ameliorate Achilles TENDINOPATHY Through Tissue Penetration and Dual Regulation of the PI3K/AKT and MAPK Signaling Pathways 1.00
Microbial Rhamnolipid‐Stabilized mRNA Nanovaccines Enhance Adaptive Immunity via Dendritic Cell Targeting 1.00
Bioengineered CBD‐hBD‐3 Fusion Peptide‐Functionalized Collagen Scaffold Reprograms Fibroblast Fate to Attenuate Fibrosis and Promote Multilayer Vaginal Regeneration 1.00
Photothermal Hydrogel with Gel–Sol Transition for Programmed Antibacterial and Wound Healing 1.00
Multifunctional Hydrophilic Selenium-Polyurea for Controlled Ion Release of Biodegradable Alloys and Immuno-osteogenic Synergistic Modulation 1.00
Hierarchical Mineralization Buffer Zone for Dentin Interface Reconstruction via Protein-Guided Nonclassical Mineralization 1.00
Noninvasive, Electro‐Boosted Catalytic Anti‐Inflammation System for on‐Demand Osteoarthritis Treatment 1.00
Mitochondria-Targeting Nanocuproptosis Breaks Immune Resistance 1.00
A Thermoplastic and Visualizable Bone Scaffold Dynamically Enhances Hemostasis and Osteogenesis in Bone Defects 1.00
Rational Design of Lamellar Heterostructural Mg/PLLA Composite Membrane Enables Spatiotemporal-Sequential Neuro-Vascularized Bone Regeneration 0.93
Improvement of Paracrine and Tissue Regenerative Functions of Mesenchymal Stem Cells via Nanostructure‐Mediated Localized Mild Photothermal Signals 1.00
Atomic‐Precision NiCo Dual‐Atom Nanozybiotic for Drug‐Resistant Infections and Tissue Repair 1.00
3D‐Printed StrontiumSilicate Hydrogel Scaffold Promotes Sensory Innervation and Tissue Regeneration Through Modulating Macrophage Senescence 1.00
Bioinspired Hydrogel Prepared by Core-Shell Nanofibers: Accelerating Wound Healing via Macrophage Polarization Modulation 1.00
Injectable Dual-Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration 1.00
Disentangled Hydrogel With Rare Earth-Activated Multi-Enzymatic Activity Reverses the Pathological Vicious Cycle by Establishing a Closed-Loop for Postoperative Melanoma Treatment 1.00
Bimetallic MOF-Incorporated Hydrogel Scaffolds for Astaxanthin Delivery: Remodeling Bone Microenvironment and Accelerating Bone Repair 1.00
Janus Piezoelectric Fibrous Scaffolds with Ultrasound‐Triggered Electroresponsive Drug Release for Dual‐Lineage Induction and Immune Microenvironment Remodeling in Tendon‐Bone Interface Regeneration 1.00
Endogenous Glucose/pH Dual‐Responsive PEEK Implant With Cascade‐Amplified Antibacterial and Osteogenic Activities for Infected Diabetic Bone Defects 1.00
Photothermal‐Driven Spatiotemporal Delivery of Bioactive Facilitators for Coordinated Cartilage and Subchondral Bone Regeneration in Osteoarthritis 1.00
Functionally Designed Liquid Crystal Elastomer Foams for Cartilage Regeneration 1.00
ROS-Responsive Titanium Implant Coatings Enhance Osteoporotic Osseointegration via Microenvironment Remodeling and Mitochondrial Repair 1.00
An Ultrafast Self-Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine 1.00
Hierarchical Silk Fibril Networks Exhibit Structure Dependent Mechanical Performance 1.00
Mitochondrial‐Targeted Ultrasmall Hydrophobic Cationic Graphene Nanosheets Potentiating Tumor Photoimmunotherapy 1.00
A NIR‐Responsive MXene‐Based Hydrogel with Antibacterial and Repair‐Promoting Functions for Treating Infected Wounds 1.00
Spatiotemporally Orchestrated H2S/NO-Releasing Stent for Synergistic Vascular Healing 1.00
A MOF‐based Core–Shell System Enables Controlled Release and Ordered Assembly of Nano‐Hydroxyapatite for Enamel Remineralization 1.00
Ultrasound‐Propelled Antioxidant Nanobowls for the Treatment of Osteoarthritis 1.00
A Rapid In Vitro Endothelialization Approach for Small-Diameter Vascular Grafts via Covalent Reaction 1.00
Fluorescence/Colorimetric Lateral Flow Immunoassay Based on Dual-Aptamer Domain Recognition and Upconversion Signal Amplification for Sensitive H1N1 Hemagglutinin Detection 1.00
Engineered Poly(ethylene glycol)‐Alendronate‐Magnesium Hydrogels Potentiate Site‐Specific Immunomodulation for the Healing of Osteoporosis Fractures 1.00
Dual-Network Bioactive Implant Promotes Weight-Bearing Bone Healing via Mechano-Bioelectric Coupling 1.00
Thermoelectric Bionic Skin Promotes Diabetic Wound Healing by Restoring Bioelectric Field Microenvironment 1.00
Nanoparticle Endocytosis Mediated Intracellular Ion/Small Molecule Storm Triggered Mitochondrial Repair Determined Macrophage Reprogramming for Accelerate Diabetic Wound Healing 1.00
Bioinspired Alginate/α-TCP Organic–Inorganic Interpenetrating Network Microspheres for Bone Repair 1.00
Piezoelectric Catalysis‐Induced Intratumoral Carbon Monoxide Explosion for Tumor Respiration Inhibition 1.00
Non-Thermal Plasma-Induced Selective Glycosidic Cleavage in Chitosan Produces Multifunctional Antibacterial Wound Care Biomaterials 0.25
A Versatile Approach to Synergistically Combine Physical Barriers and Bioactive Agents for Intrauterine Adhesion Prevention 0.94
Ion‐in‐Conjugation‐Enabled Remineralized Scaffold for Spatiotemporal Control of Infection and Bone Regeneration 1.00
An off‐the‐Shelf Injectable MSC Hydrogel with Microenvironment‐Driven Responsiveness for Precision Osteoarthritis Treatment 1.00
The Coupling of Gradient Mechano-Electrical Microenvironments Promotes Interface Regeneration via Ca2⁺ Signaling Activation 1.00
Band Alignment in TiO2/UiO-67 S-Scheme Heterojunction for Anti-Interference Phosphate Sensing 1.00
PEG-Free Monosialoganglioside Lipid Nanoparticles with Spleen-Selective mRNA Delivery for Cancer Immunotherapy 1.00
A Morinda Officinalis Extracellular Vesicles‐Encapsulated Redox Homeostasis Modulatory Hydrogel Promotes Growth Plate Injury Repair by Regulating the Oxidative Stress Microenvironment 1.00
Stem Cell Fishing at Bone‐Implant Interface: A Cell‐Clicking Bioadhesion Strategy to Enhance Osteointegration 0.95
Bioimplantable Bifunctional Zinc/Magnesium–Oxygen Battery for Synergistic Gas Therapy and Hypoxia‐Activated Chemotherapy 1.00
Melanin‐derived Biomimetic Nanoparticles Improve Patency and Tissue Regeneration of Vascular Grafts via ROS Scavenging and Immunomodulation in an Atherosclerotic Rat Model 1.00
Modular Integration of Self-Adjuvanting mRNA Delivery with Real-Time Vaccine Efficacy Tracking for Timely Optimization of Cancer Immunotherapy 1.00
Biodegradable Dual-Stimuli Hydrogel Scaffoldoid Synergizing Piezoionic and Lithium-Ion Release for Critical-Sized Bone Defect Regeneration 0.94
Biodegradable Anti-Stenosis Microsurgical Implantable Hydrogel Stent for Efficient Vas Deferens Recanalization 0.86
Engineering a Biomimetic DentinLayer via Light-Responsive Self-Mineralizing Collagen Matrix for Dentin Repair 1.00
Biomimetic Nanofabrication by Silkworm-Inspired Spinning: A Supertough Nano-Skin Fiber Through Sequenced Interactive Fiber-Microfluidics 1.00
Ultrafast Electrochemical Biosensor for SARS-CoV-2 Viral Nucleic Acids Sensitive Detection Using Os-Complex/3D Vertical Graphene Dual Signal Amplification 1.00
A Biothiol‐Reactive and Mitochondria‐Targeting Photosensitizer for Dual‐Modal Antitumor Treatment Combining Photodynamic and Nitric Oxide Therapies 1.00
Advanced Electroactive and Anti‐Inflammatory Sutures for Enhancing Tendon and Bone Regeneration to Promote Repair of Achilles Tendon Sleeve Avulsion 0.77
A Self‐Reinforcing Metabolic Nanojammer for Activating Cascade‐Augmented Cuproptosis‐Driven Immunotherapy 1.00
Multifunctional Nanoparticle Reinforced GelMA Hydrogel for Osteoporotic Pathophysiological Microenvironment Improvement and Bone Defect Regeneration 1.00
Ultrasound‐Driven Piezoelectric Bi‐Ru Heterojunctions for Water‐Splitting Gas Therapy in Tumors 1.00
Regional Cellular Reprogramming via a Non‐Coding RNA Engineered Electrospun Fibrous Patch 1.00
Bioinspired Stratified Janus Hydrogel Enables Neuro‐Osteogenic Regeneration via Microenvironment‐Matched Repair After Tooth Extraction 1.00
pH‐Triggered Aggregation of Polylysine Nanoparticles Enhances TNF‐α siRNA Delivery for Rheumatoid Arthritis Therapy 1.00
Immunomodulation‐Based Multifunctional Decellularized Matrix Bioink Derived from M2 Macrophages Remodels the Bone Microenvironment via Neurogenesis and Angiogenesis 1.00
Vascular Intima‐Biomimetic Bilayer Hydrogel Coating of Central Venous Catheters with Dual‐Modal Anti‐Coagulation and Self‐Adaptive Immunomodulation 1.00
Biomimetic Microgrooved Methacrylated Silk Fibroin Cartilage Scaffold for Tracheal Injury Repair 1.00
In Situ Engineering Mesenchymal Stem Cells for Osteogenic Differentiation to Reverse Inflammaging and Restore Periodontal Bone Homeostasis 0.92
Nano‐Interlocking Enhanced Electroactive Dressing: Electromagnetic Induction for Accelerated Diabetic Wound Healing and Wound Microenvironment Monitoring 1.00
Biodegradable Polymeric Nanoparticle Employing a Photodynamic/Photothermal/Thermodynamic Combination Strategy for Treatment of Acute Maxillofacial Wound Infections 1.00
From Snapshot to Movie: Visualizing Native Silk Spinning Defines the Paradigm for Bio‐Inspired Spinning 0.86
Amorphous Region Modifications Enhance Genetically Engineered Spider Silk for Advanced Wearable Applications 0.72
Label‐Free and Low‐Power Driven Cancer Biomarker Detection Enabled by 2D Hexagonal Titanium Oxide 0.39
Biomimetic Grooved Spinneret Enables High‐Performance Regenerated Silk Fibers Surpassing Natural Silkworm Silk 1.00
Metal‐Organic Nanosheet Gels: Hierarchically Porous Materials for Selective Loading and Differential Release 0.50
The Rational Design of Pt Single Atoms‐Bridged Nanozyme with Enhancing Direct Electron Transfer Pathway for Glucose Oxidation 1.00
Bonyzymes: Efficient Anti‐Inflammatory, Antibacterial and Osteogenic Agents for Peri‐Implantitis Reconstruction Treatment 1.00
Pubertal Bone Matrix Microparticles Support Rapid Generation of Mini‐Bone Organoids and Minimally‐Invasive Injection in Repairing Bone Defect 1.00
Alkaline Gradient Induced Hydrogen Bond Stabilized Adhesive Dressings for Gastric Ulcer Healing 1.00
Metformin‐Induced Fibrillation of Copper Formate into Biocompatible Antibacterial Hydrogel for Enhanced Fungal Infection Wound Healing 1.00
Histidine‐Engineered ZIF‐8 Nanoparticles for High‐Efficiency siRNA Delivery and Gene Therapy of Intervertebral Disc Degeneration 1.00
Biomimetic Bacterial Framework‐Driven Point‐of‐Care Platform Enables Broad‐Spectrum Bacterial Sensing via PAMPs‐Triggered Competitive Recognition 0.90
Streamlined Synthesis of Ga‐Cu Dual Single‐Atom Nanozymes for Advanced Electrochemical Sensing Applications 0.79
Engineering Mesenchymal Stem Cells with Antioxidant Catalase‐Loaded Metal–Organic Frameworks for Targeted Spinal Cord Injury Therapy 1.00
Electroactive Dressing Induces Piezoelectric Signals and Ca2⁺ Activation to Enhance Osteoblast Differentiation and Bone Regeneration in Negative Pressure Therapy 1.00
Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction 0.96
Nanofiber-Reinforced Self-Adaptive Hydrogels with Desired Sequential Delivery Capability of Bioactive Factors and Magnesium for Vascularized Osteochondral Regeneration 0.90
A Mitochondria‐Targeted Biomimetic Nanocarrier Improves Oxygen Metabolism and Potentiates Chemo‐Sonodynamic Antitumor Therapy 1.00
“Small Dots, Multiple Functions”: Unveiling the Veil of a Bioactive Quercetin Carbon Dot and Its Multifaceted Antibacterial and Osteogenesis Mechanisms for Infectious Bone Defect Repair 0.94
Charge and Size‐Variable Biodegradable Nanocomposites for Self‐Reinforcing CDT, PTT, and Chemotherapy: Augmented Cuproptosis and Ferroptosis against Tumor Hypoxia via Glycolysis/Redox Dual Disruption 1.00
Macrophage‐Targeted Efferocytosis Therapy Promotes Diabetic Wound Healing via Cellular Level Debridement 1.00
n-Butanol Enables OMVs as Heat-Responsive Nanometer Ultrasound Contrast Agents for Tumor Imaging 1.00
Mechanically‐Compliant Magnetoelectric Sutures for Wound Management 1.00
Molecular Dynamics Simulations of Hybrid Cell Membrane‐Coated Porphyrin Nanoparticles for Enhanced Photochemotherapy of Breast Cancer 1.00
An Ultrasound-Responsive Hydrogel for Diabetic Wound Electrotherapy Based on Interfacial Ion/Electron Transfer 1.00
Janus Fibrous Dressing with Controllable Nitric Oxide-Releasing and Unidirectional Exudate Transport Activities for Bacteria-Infected Burn Wound Therapy 1.00
Tempo‐Functionalized Janus Hydrogel Crosslinked by Tandem Dynamic Covalent Bonds for Internal Organ Injury Repair and Deep Second‐Degree Burn Wound Healing 1.00
Ultrasound‐Driven Piezoelectric Strategy and Performance: Polyurethane‐Based Functioning Networks in Actuating Bone Repair 1.00
Injectable Spiky Artificial Peroxidase‐Encapsulated Hydrogels for Bioadaptively and Synergistically Combating Endometrial Infections 0.91
3D‐Printed Carbon Scaffolds With Osteoinductivity via Nanotopography‐Mediated Mechanotransduction 1.00
58 56.07
A Structurally Stabilized Lipopolymer Nanoplatform Targeting Pan‐Tissue Antigen‐Presenting Cells Enables Durable in situ mRNA Cancer Immunotherapy 1.00
Igniting Endogenous Calcipoptosis via ER-Mitochondrial Calcium Shuttle Hijacking for Potent Antitumor Immunity 1.00
Disrupting KAT8 Liquid–Liquid Phase Separation with Hybrid Vesicle–Liposome Platform for Enhanced PD-L1 Blockade Treatment 1.00
Adhesive Microneedle-Nanosheets With Temporally Orchestrated Antimicrobial, Immunomodulatory, and Osteogenic Functions for Periodontal Regeneration 1.00
Brake–Drive Osteo System: Sequential Modulation of the Inflammatory Microenvironment and Osteogenesis for Osteoporotic Bone Defect Regeneration 1.00
Osteogenic Nanozymes for Diabetic Bone Regeneration via Synergistic Antioxidant and Osteoinductive Functions 1.00
Photosynthetic Nanobacteria Drive Metabolic-Immune Synergy for Hypoxia-Resistant Cancer Therapy 1.00
Unlocking an Efficient SOD-to-CAT Catalytic Relay in a MOF Nanozyme via Dopamine-Driven Interfacial Nanoreconstruction for Osteoarthritis Therapy 1.00
Micropore‐Confined ROS‐Responsive 3D‐Printed Shell‐Core Scaffolds for Long‐Term NO Release to Orchestrate Immunomodulation and Angiogenesis in Diabetic Bone Defect Repair 1.00
Safeguarding VSMC Contractile Phenotype With In Situ circRNA‐mediated Endothelial Olaratumab Engineering to Prevent Vascular Graft Stenosis 1.00
Trace Detection of Multiple Macromolecular Biomarkers in Saliva by Enzymatic Responsive Serial‐Nanofluids Strategy 1.00
DNA Supramolecular Hydrogel Alters Exosomal microRNA Atlas and Paracrine Secretory Profile of MSCs to Promote Bone Remodeling and Ameliorate Osteoradionecrosis of the Jaw 1.00
Fusion Peptide-Incorporated Lipid Nanoparticles Boost Endosomal Escape and Enhance Cytosolic mRNA Delivery 1.00
Engineering Asymmetric and Highly Exposed Fe Single‐Atom Nanozymes for siMMP13 Delivery and Ferroptosis Inhibition in Osteoarthritis Therapy 1.00
Bioinspired Engineered Virus-Mimetic Vesicles for Enhanced Cytosolic Delivery of STING Agonists Into Dendritic Cells 1.00
A 3D-Printed Piezoelectric Scaffold With Bio-Inspired Gradient and Dynamic Adaptation for Tendon Regeneration 1.00
Optimizing Peptide Ionizable Lipids Enables Efficient and Low-Toxicity mRNA Delivery for In Vivo Prime Editing and Protein Replacement Therapy 1.00
Combinatorial Assembly of Biomimetic Janus Membrane with Multiscale Architectures for Guided Bone Regeneration 0.93
A Bio‐Orthogonal Engineered Chitosan Platform for Enhanced Mesenchymal Stem Cells Delivery and Function in Peripheral Nerve Repair 1.00
Bioinspired Engineering of Living Materials to Reconstruct Stromal-Parenchymal Interactions for Post-Stroke Neural Regeneration 1.00
Stiffness‐Gated Cytoplasmic mRNA Delivery Through Engineered Membrane Fusion for Breast Cancer Immunotherapy 1.00
Endogenous Metal Ion‐Enriched Immunostimulating Biomimetic Scaffold Improves In Situ Bone Regeneration 1.00
Coupling Mitochondrial Homeostasis to Oxi‐Inflamm‐Aging Network Disruption via Peptide‐Functionalized Nanocomposite Hydrogel for Osteoarthritis Intervention 1.00
Metabolic Osteoimmune Biodegradable Zn–Mn Alloys: High Strength-Ductility and In Situ Vascular-Osteogenic Coupling 1.00
Reprogramming mRNA Delivery Tropism via Nitrogen-To-Sulfur Substitution in Ionizable Lipids 1.00
Small Molecule‐Driven Organic Electrochemical Transistors for Rapid, Ultrasensitive and Amplification‐Free Detection of RNA Biomarkers 0.66
Lock-and-Shield Strategy Enables Stable and Stimuli-Responsive Tumor-Targeted Gene Delivery 0.38
Engineered Cryo‐Shocked Cancer Cells Deliver Dual‐Function Gene Medicines for Melanoma Immunotherapy 1.00
Akkermansia Muciniphila-Inspired Oral siRNA Delivery by Active Matrix-Penetration and Intracellular Endoplasmic Reticulum Accumulation 1.00
Resolving the mRNA Encapsulation‐Release Trade‐off via Compensatory Forces in Engineered Ionizable Lipids 1.00
A Pseudo-Mytilus Edulis Foot Protein-Based Hydrogel Adhesive with Osteo-Vascular-Immune Coupling Effects for Osteoporotic Bone-Implant Integration 1.00
siAkt2‐Loaded Nanoparticles Reprogramming Macrophages to M2 Phenotype for Effective Bone Defect Repair 1.00
Modular Assembly of Lipid Nanoparticles for Targeted mRNA Therapeutics and Vaccines 1.00
Wrinkled Layered Sulfide With Tunable Channels Unlocks Precision in Rare Earth Extraction From Radioactive Wastewater 1.00
DNA-Scaffolded Bispecific Antibodies Enhance Mesenchymal Stromal Cell Therapy for Inflammatory Bowel Disease 1.00
Construction of Diverse Calcium-Based Nanomaterials through a Microemulsion Method for Pyroptosis-Initiated Antitumor Immunotherapy 1.00
Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases 1.00
Environmental Response Temporal Release Injectable Hydrogel for Controlled Growth Factor Release to Enhance Inflammatory Periodontal Bone Defect Regeneration 1.00
Calcium Phosphate Nanoparticle-Immobilized Macrophage-Derived Extracellular Vesicle Nanohybrid Facilitates Diabetic Bone Regeneration 1.00
Supramolecular Amino Acids‐Encoded Nanodots (SEND) with pH‐ and Ion‐Responsive Phase Separation for Serum‐Tolerant Cytosolic Protein Delivery 1.00
Temporal Immunomodulatory Hydrogel Regulating the Immune-Osteogenic Cascade for Infected Bone Defects Regeneration 1.00
Diatom‐Inspired Scaffold for Infected Bone Defect Therapy: Achieving Stable Photothermal Properties and Coordinated Antibacterial‐Osteogenic Functions 1.00
A Readily Synthesized All‐In‐One Nanowire Hydrogel: Toward Inhibiting Tumor Recurrence and Postoperative Infection 0.85
Bio-Orthogonal Engineering of Neural Stem Cells with Membrane-Bound Microsatellites for Enhanced Brain Repair 1.00
Artificial Transmembrane Oligopeptide-Integrated Interferon mRNA with Monoclonal Antibody to Improve Specificity and Efficacy of Cancer Immunotherapy 1.00
Engineered Virus‐Like Nanoparticles Enable Multimodal Protein Degradation for Enhanced Tumor Therapy 0.83
Host Cell Membrane‐Cloaked Nanomedicine Reprograms Endothelial Surface for Enhanced Patency in Allogeneic Vascular Grafts 1.00
Piezoelectric Injectable Anti‐Adhesive Hydrogel to Promote Endogenous Healing of Tendon Injuries 1.00
Bioinspired Immunomodulatory Scaffold Based on Mineralized Lotus Stalks Laden with MnCO Microspheres for Accelerated Bone Regeneration 1.00
Self-Growing Scaffold for Spatial and Border Expansive Regeneration 1.00
An Environmentally Responsive Molecular Engineering Framework for Subcellular Drug Translocalization 0.83
Clinically Accurate Diagnosis of Alzheimer's Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers 0.83
Inflammation‐Activatable Nanoscavengers for Sustainable Cell‐Free DNA Capture and Cleavage 1.00
Nanozyme‐Reinforced Hydrogel Spray as a Reactive Oxygen Species‐Driven Oxygenator to Accelerate Diabetic Wound Healing 1.00
Biocatalytic and Redox‐Regulated Nanoarchitectures for Precision Inflammation and Immune Homeostasis Modulation to Combat Rheumatoid Arthritis 1.00
Noninvasive Optogenetics Realized by iPSC‐Derived Tentacled Carrier in Alzheimer's Disease Treatment 1.00
Ultrasound‐Triggered Nanoparticles Induce Cuproptosis for Enhancing Immunogenic Sonodynamic Therapy 0.88
Nanoconfinement of Ammonia Borane via Hybrid-Phased Titanate Nanocrystals Enables Sustained H2 Release for Diabetic Bone Repair 0.89
2 1.07
Rora Regulates Hematopoietic Stem Cell Phenotypes and Progression of Chronic Myelogenous Leukemia 1.00
Pharmacological inhibition of glutamate dehydrogenase 1 (GLUD1) improves functional recovery of neuromuscular junctions and muscle function in Duchenne muscular dystrophy. 0.07
1 0.93
Prostaglandin I2 Receptor Activation Promotes Alveolar Regeneration via the JUN/p53 Pathway 0.93
292 283.93
Mitochondria-Targeted Fluorescent Probe for Super-Resolution Imaging of HNO in Lung Cancer 1.00
Integrating Acridinium Ester with a Soluble Macromolecular Amplification Carrier for Ultrasensitive Detection of Aβ1-42 in Plasma 1.00
Localized Dual-Cycle Amplification Integrating Entropy-Driven Reaction and Catalytic Hairpin Assembly for miRNA Imaging in Living Cells and Tissues 1.00
One-Pot Ligation-Recombinase Polymerase Amplification-Clustered Regularly Interspaced Short Palindromic Repeats/Cas12a-Powered Trimode Lateral Flow Assay for Sensitive MicroRNA Detection 1.00
Digital Counting of Quantum Dots Nanobeads on Lateral Flow Test Strips Enables Ultrasensitive Point-of-Care Diagnostics 1.00
A Disposable CRISPR-Nanozyme Electrochemical Biosensor for Rapid and Sensitive Detection of Breast Cancer Circulating Tumor DNA 0.88
Target-Induced Tandem Built-In Electric Fields in the Hollow SnS2/ZIS@ZnS Heterojunction for the Photoelectrochemical Immunoassay 1.00
Rapid and Specific Detection of Gastric Cancer EVs Using a Cas12a-Powered Aptasensor with a Novel Targeting Aptamer 0.92
Single-Atom Fe/Au Nanozymic Electrode to Accelerate Glucose Oxidation for Self-Powered Sensing 1.00
A Tailored Monoclonal Antibody for Visual Detection of an Emerging Insecticide Chlorfenapyr: Rational Hapten Design and Molecular Insights 1.00
One-Step Chemiluminescent Immunoassay for the Key Synthesis Protein of Ochratoxin A Using a Shark Single-Domain Antibody-Alkaline Phosphatase Fusion Protein 1.00
Integrated Microfluidic SERS Sensor Featuring Au NPs@Cu MOF/Hydrogel for Label-Free and Specific Creatinine Detection 0.88
Hydrogel RT-LAMP Enables Rapid, Quantitative Assessment of Mycobacterium tuberculosis Immune Responses 1.00
Rational Hapten Engineering Enables a Monoclonal Antibody for the Masked-Mycotoxin Zearalenone-14-Glucoside and Field-Deployable Digital Immunoassays 1.00
Self-Hybridization Chain Polymerization-Driven Transcriptional Synthesis of Fluorescent Aptamers for One-Step Detection of Cancer-Associated RNA Biomarkers 1.00
Clustered Regularly Interspaced Short Palindromic Repeat-Based Colorimetric Aptasensor Combined with Smartphone Imaging and Deep Learning Enables Selective Recycling and Visual Prediction of Microplastics in the Environment 1.00
Paper-Based Tests with a Rapid Plug-and-Play Aptameric Switch for Metabolic Disease Diagnosis at the Point of Care 1.00
Single-Cell Analysis of Zinc Ions During Electrical Stimulation-Induced Pyroptosis by DNAzyme-Functionalized Glass Nanopipettes 1.00
A Droplet-Free and Oil-Free Microfluidics Based on Self-Pumping Hydrogel for Point-of-Care Multiplex Digital Nucleic Acid Detection 1.00
An All-in-One Microfluidic Platform for POCT-Ready Nucleic Acid Extraction from Heterogeneous Clinical Samples 1.00
Engineering High-Performance Aptamers via Optimized SELEX and Structure-Guided Dimer Assembly for Clinical Malaria Diagnostics 0.44
Double-Stranded Universal Probe Strategy Enables Cost-Effective and Versatile Nucleic Acid Amplification Tests 1.00
Electrocontrolled Injection-Coupled Droplet Microfluidic Platform for Antimicrobial Resistance Screening 1.00
Target-Amplification-Free Detection of Pathogenic Bacteria Via a Cascaded Nuclease Reaction 1.00
Chemiluminescent Nanoflower with Inherent Oxygen Vacancies for Coreactant-Free and Label-Free Immunoassay of pTau181 1.00
A Wearable Supramolecular Fingertip Sensor for Colorimetric Detection of Food-Derived Tyramine 1.00
PEG-Modified Selenium Nanoparticles Dramatically Increases Antibody Binding Sites for Ultrasensitive Point-of-Care Detection of NT-proBNP 1.00
Site-Specific Evolution of DNA Aptamers to Detect ADAR1p150 in Complex Biological Samples 1.00
Cell Probe Cocktail Enables Ratiometric miRNA Detection with Enhanced Sensitivity and an Extended Dynamic Range 1.00
Organic–Inorganic Core–Shell Satellite Nanostructures for Dual-Readout Detection of Escherichia coli O157:H7 1.00
Graphene Field-Effect Transistors Loaded with DNA Walkers for Detection of miRNAs 1.00
SIMPLE-CRISPR: A Sample-to-Result Platform for Point-of-Care Detection of Nucleic Acids via a Functionalized Magnetic-Bead-Based CRISPR Assay 1.00
Electrochemiluminescence Biosensing Platform Based on CRISPR/Cas12a and DNA Nanotweezer-Mediated Catalytic Hairpin Assembly Amplification 1.00
Direct RNA Triggering of Cas12a through the Native crRNA Architecture Enables Clinical Nucleic Acids Diagnostics 1.00
Bacterial Metabolism-Driven Dual-Enzyme Cascade Colorimetric Sensor for Antimicrobial Susceptibility Testing with Readily Interpretable Signals 1.00
One-Pot CRISPR/Cas12a Assay Based on Ultrashort HDA for Ultrasensitive and Universal Nucleic Acid Detection 1.00
High-Speed, Label-Free Antimicrobial Susceptibility Testing in Picoliter Droplets: Combining Cage-Based Phase Contrast Microscopy with YOLO-SAM Algorithm 1.00
Side-Port Puncture Needle-Assisted, Multistep Vacuum-Driven Microfluidic Chip for Multiplexed Molecular Analysis 1.00
Influence of Molecular Crowding on Aptamers and Application in Lateral Flow Assays 1.00
Hydroxyl Radical–Activatable NIR-II Ratiometric Fluorescence Probe for Visualization In Vivo Tracking of Oxidative Stress and Therapeutic Response in Arthritis 1.00
TOI-IGRA: A Fingertip Blood Biosensing Technology for Decentralized Quantification of Pathogen-Specific T-Cell Responses 1.00
High-Affinity Three-Way Junction Aptamers for Sensing Cationic Polymyxin Antibiotics 0.50
Rigid Restriction-Enabled Ultrabright Luminescence through Feather-like Metal-AIEgens Frameworks and Coupling the Collaborative Interfacial Recognition Mechanism for Pathogen Diagnosis 1.00
Microwave-Assisted Synthesis of PNA@AuNRs with Temperature Gating for Precise Amplification of Nucleic Acids 1.00
Culture-Free Microfluidics for Ultra-Rapid Antimicrobial Susceptibility Testing with AI in Resource-Limited Settings 1.00
A Hydrogel-Based 3D Microfluidic Platform with Optimized Flow and Mass Transfer for Rapid Antimicrobial Susceptibility Testing 1.00
pH-Responsive 1,8-Naphthalimide Probe for a One-Step Loop-Mediated Isothermal Amplification Assay 1.00
Breathomics-Guided Solid-State Sensor for Noninvasive Point-of-Care Diabetes Screening 1.00
Bridging Target Recognition with Direct Molecular Counting: A DNA Framework Converter-Mediated nFCM Assay Platform for Quantifying Diverse Biochemical Analytes 1.00
Aptamer-Mediated Proximity Labeling (ApMPL) for Spatially Resolved Deciphering of Cell Membrane Protein Interactomes 1.00
Atomic Fe-Centered Hemin–TiO2 Graphdiyne Nanozyme Sensor for Colorimetric Fingerprinting of Bacterial Extracellular Vesicles 1.00
Copper-Based MOF Derivative with Enhanced Electrocatalytic Activity for Highly Sensitive and Ultrafast Detection of Salivary Glucose 1.00
Catalytic Amplification-Mediated Single-Nanotag Assembly for Sensitive Detection of Circulating microRNAs 0.86
Pronounced Fluorescence Polarization Enhancement Driven by RPA-CRISPR/Cas12a Induced Nucleoprotein Assembly for Salmonella Analysis in Animal-Derived Food Matrices 1.00
Real-Time Acoustic Spectroscopy of Nanoparticle Sedimentation in Microfluidic Systems Using Phononic Crystal-Based Ultrasonic Interferometry 0.25
DNA-Fueled Molecule Machine-Mediated Atom Transfer Radical Polymerization Amplification for 17β-Estradiol Assay in Clinical Samples 0.80
Feedback-Guided SERS-Photothermal Patch for Maintaining Redox Homeostasis in Diabetic Foot Ulcers 0.78
Laser-Printed Electrochemical Microfluidic Aptasensing Chip for Simultaneous Detection of Multiple Pesticides 1.00
Aptamer-Mediated Protein Corona In Situ Multiplex Microfluidic Detection for Cancer Diagnosis 1.00
Ultrasensitive Electrochemiluminescence Detection of Dual Tumor Markers on Living Cell Surface with a Closed Bipolar Electrode Array Chip 1.00
Micropore Confinement in Flow Systems Enables Subsecond Bipolar ECL Biosensing 1.00
An Integrated 3D-Printed Portable Device Coupling Bimetallic FeCo-MOF Nanozymes with Freeze-Dried Hydrogel Carriers for Point-of-Care Testing of Serum Acid Phosphatase 1.00
One Blow To Obtain Integrated Information on Metals, NO, and Metabolites in Breath Gas by Mass Spectrometry 1.00
A High-Sensitive Photothermal-Readout Strategy for Commercial Lateral Flow Immunoassays with an Optical Microfiber Mach–Zehnder Interferometer 1.00
A Real-Time, Programmable, and Multiplex Ligation Chain Reaction-MNAzyme Platform for Single-Nucleotide Variant Detection 1.00
Wettable Porous Arrays with Structural Color Barcodes Integration for Multiplex Urinary Tract Infection Bacteria Screening 1.00
Eutectogel-Based Antifouling Interface: Addressing Sensitivity and Accuracy Challenges in Complex Serum 1.00
Selection of a High-Affinity Aptamer for Phalloidin and Application in a Dual-Mode LRET/Colorimetric Aptasensor 1.00
Integrated Dual-Modality Biosensor for Antimicrobial Susceptibility Testing and Antibiotic Prescription Guidance 1.00
Development of a Paper-Based SERS Platform for On-Site Separation and Detection of Mercury Species in Aqueous Environments 1.00
A Robust Nonfouling Biosensor Based on an Engineered Multifunctional Monocyclic Peptide for Electrochemical Detection of Biomarkers in Human Blood 1.00
DNAzyme-Powered Rolling Circle Amplification for the Synthesis of Hairpin DNA-Templated Fluorescent Copper Nanoclusters: A Label-Free miRNA Sensing Platform 0.40
Quantification of Hydrogen Sulfide in Single Living Cells by Azido-Functionalized Glass Nanopores 1.00
Push-Button Microfluidic Platform with Dual-Signal Nanoprobes for Enhanced Sensitivity Detection of Healthcare-Associated Infection Pathogens at Point-of-Care 1.00
An Integrated Centrifugal Microfluidic Point-of-Care Low-Cost Chip for Rapid Pathogen Nucleic Acid Detection and Diagnosis of Bloodstream Infections 1.00
Wet–Dry–Wet Experiments Enable Simultaneous Aptamer Isolation and Critical Binding Domain Identification 1.00
Three-Dimensional Fluorescence Fingerprint Integrated PCR Enables Accurate Analysis of 9 Pathogens 1.00
Long-Lived Phosphorescent CDs@SiO2 Coupled with Magnetic Quencher Fe3O4@PDA: A Dual-Mode Lateral Flow Immunochromatographic Assay for Sensitive Determination of Acetamiprid 1.00
Rapid and Sensitive Visual Detection of Gene Mutations via LIVE-SNP 1.00
Self-powered Photoelectrochromic Biosensor for Visual Detection Using a Distance-Based Signal Readout 1.00
Electrochemical Gating of d-Band Engineering in Hierarchically Bridged Dual-Site Nanozymes for Synergistic Cascade Catalysis and Wearable Biosensing 0.88
Dual-Mode Lateral Flow Assay for Simultaneous Quantification of Antibiotic and Bacteria 1.00
Novel One-Pot Detection of Tumor mRNA Vaccine by the Target Serving as crRNA of the Split Cas12a System and Synergistically Triggering an Entropy-Driven Reaction 1.00
Exploring the Feasibility of Paper-Based Substrates for User-Friendly Electrochemiluminescent Sensors 0.17
Fabricating a SMVF@GO@Ag Composite Aerogel SERS Sensor for the Enrichment and Label-Free Detection of Urinary VOCs 1.00
Controlled Nanozyme-Substrate Accessibility for Ultrasensitive Electrochemical Detection of miRNA 1.00
Gold-Coated Optical Fiber Electrode for In Situ Monitoring of Hydrogen Peroxide Released from Living Cells via Transmitted Electrogenerated Chemiluminescence 1.00
CRISPR-AD: Combinational Detection of Blood Protein and miRNA with Digital CRISPR-Based Assay Enable to Improve the Diagnostic Performance of Alzheimer’s Disease 1.00
Rapid and Sensitive Pathogen Detection and Viability Evaluation: A Lateral Flow Assay Based on One-to-Multiple Signal Amplification 1.00
A Novel 2-Chloro-4-Nitrophenol Photoelectrochemical Sensor Based on MWCNTs@MIL-68(In) Derivatives and In2O3 Composite Films 1.00
Chitosan-Functionalized Magnetic Graphene Oxide Nanocomposites Enable High-Purity mRNA Enrichment To Avoid False Positives in LC-MS/MS Modification Profiling 1.00
Aptamer-Functionalized Microchannel-Gated Field-Effect Transistor Biosensor for In Vivo Detection of Dopamine 1.00
Optical-Antenna-Enhanced LED Biochips for Femtomolar Detection of Protein Biomarkers 1.00
Ultrasensitive CRISPR Platform Enables Rapid and Extraction-Free Detection of Viral Nucleic Acid 1.00
UV-DOAS Combined with Spectral Projection Decoupling Neural Network (SPDNN): An Online System for the Simultaneous Detection of Ammonia and Isoprene at Sub-ppb Levels 1.00
Rapid Single-Cell Phenotypic Antifungal Susceptibility Testing on a SlipChip Enabled by Deep Learning 1.00
An AND-Logic Gate-Based Biosensor for Simultaneous Detection of SARS-CoV-2 Nucleic Acids and Nucleocapsid Proteins 1.00
From Hapten Design to Mechanism Exploration: Developing a High-Specificity Immunochromatography Strip for Fluridone Detection 1.00
Synergistic CRISPR/Cas12a-Nanozyme System for Iontronic Sensing of Site-Specific Septin9 Methylation 1.00
A Simple and Rapid Bst Polymerase-Catalyzed Isothermal Exponential Amplification Reaction for Multiplex Detection of MicroRNAs 1.00
AI-Assisted Multiplex SYBR Green I-Based qPCR for the Identification and Quantitative Analysis of Oral Microbiota 1.00
A Reusable Dual-Mode Aptasensor Based on Bipolar Electrode for Sensitive Detection of Live Clostridium perfringens 1.00
Wettability-Enhanced Photothermal Vertical Flow Biosensor on a Syringe for PSA Detection Using TaTe2 Nanosheets 1.00
Application of Engineered Split Aptamers in Fluorescence-Colorimetric Dual-Mode Detection of Chloramphenicol 1.00
Recruitment of Enzymatic Labels via Glycan-Lectin Interactions for Electrochemical Immunosensing of Anti-dsDNA Antibodies 1.00
Novel Ultrafast Sample-to-Answer Microfluidic Platform for Highly Sensitive On-Site Quantification of Avian Influenza Virus 1.00
Ultrasensitive Fluorescence Detection of Lung Cancer-Related miRNAs Based on DNA Tetrahedron and DNAzyme Catalytic Reaction 1.00
Metal–Organic Framework@Gold Nanoparticles Enables Point-of-Care Diagnostics To Have Comparable Analytical Performance to Chemiluminescent Immunoassays 1.00
Ultrasensitive Electrochemical Biosensor for DNA Methylation Detection Based on Fe-MOF/PANI and Catalytic Hairpin Assembly Cascade Reaction 1.00
A Relay CRISPR/Cas12a System for Extraction-Free and Ultrasensitive Detection of Staphylococcus aureus in Complex Food Samples 1.00
Lateral Flow Strip-Compatible Nucleic Acid Testing for Facile Diagnosis of Infectious Pet Diseases 1.00
Hyaluronic Acid-Gentamicin Hydrogel and pH Indicator Mediated by Mesoporous Silica Nanoparticles as Antibacterial and Indicatable Wound Dressings for Real-Time Monitoring of the Healing Process 1.00
Device Simplification: Example of the Application of a Bifunctional Molecularly Imprinted Polymer Membrane in a Visual Photoelectrochromic Chip 1.00
Dopamine Self-Polymerization-Assisted Oriented Antibody Immobilization on a Transistor for Alzheimer’s Disease Diagnosis 1.00
A Highly Sensitive Multiplex Immunosensor for Detecting Three Sulfonylurea Herbicides: From Hapten Design to Molecular Recognition Mechanism 1.00
Fluorescent Microneedle Sensor Array for Continuously Monitoring Sodium and Hydrogen Ion Concentrations in Interstitial Fluid and Its Application in Diabetes Complication Management 1.00
Janus Metal-AIEgen Framework@Hydrogel Patch for Ultrasensitive, Multivariate Responsive, and Intelligent Point-Of-Care Sensors 1.00
Integrated Biosensing Platform Based on Bi2S3/BiFeO3 Heterojunction and BiVO4 for Ultrasensitive Organic Photoelectrochemical Transistor and Colorimetric Dual-Mode Detection of Prostate-Specific Antigen 1.00
Molecular Simulation Guided Optimization of Multi-Epitope Nanobody Affinity for Enhanced Förster Resonance Energy Transfer System Performance 1.00
Magnetic Rolling Circle Amplification-Assisted Automated Electrochemiluminescence Immunoassay for Ultrasensitive Determination of Protein Biomarkers 1.00
Development of a Self-Activating Dandelion-Shaped DNA Nanodevice for Amplified Imaging of mRNA and Precise Gene Silencing 1.00
Highly Specific Detection of miRNA Mutants Using a Combined Analysis of Functionalized Micropipette and Hybridization Free Energy 1.00
A Smart Dual-Amplification Electrochemical Analyzer: Product-Activated Tripedal DNA Walker for Glioma Grading 1.00
A Versatile CRISPR/Cas12a Autocatalytic Cascade System via Structure-Switching V-Type Split Probe for Highly Sensitive DNA Diagnostics 1.00
Hierarchically Porous Amino-Functionalized Microporous Organic Networks Coated Fiber for Sensitive Breath Metabolite Profiling: A Noninvasive Strategy for Gastric Cancer Diagnosis 0.75
Combined Use of Engineered PfAGO and LbCas12a for Nucleic Acid Detection 1.00
Selection of Allosteric DNAzymes for Theophylline Sensing by Expression-SELEX 1.00
A Dual-Signal Amplification Detection of Tumor mRNA Vaccines Based on the Novel Full-Length Catalytic Loop Initiating DNAzyme 1.00
Catalase-Driven Microflow Displacement for Rapid, Visual Antimicrobial Susceptibility Testing 1.00
Deprotonated Nanofilms-Enabled Fluorescence-Colorimetric Dual-Mode Sensing of 3-Hydroxy-2-butanone 1.00
Culture- and PCR-Free Femtomolar Detection of Antibiotic Resistance Genes in Clinical Urine via Cascaded Molecular Machines and Electrokinetic Enrichment 1.00
Digital-to-Droplet Microfluidic Platform Powered Digital Isothermal Nucleic Acid Amplification for On-Demand Detection of Post-Transplantation Infection-Causing Viruses 1.00
AI-Assisted Microfluidic Paper-Based Analytical Device with Au–Pt Nanoparticles for Multiplex, Interference-Resistant Quantification of Urinary Biomarkers 1.00
Ultra-Fast Laser Marking of TiO2/Ti Arrays on Titanium Foils for Scalable Construction of All-Metal Light-Addressable Photoelectrochemical Sensors 1.00
Efficient 2D HOF@Au SERS Substrates Synergized with the G-quadruplex Network-Based Catalytic Amplification Strategy for Low-Background Trimode Detection of Lomefloxacin 1.00
Homogeneous Femtomolar Detection of P-tau181 via Proximity Extension and CRISPR/Cas Technique 1.00
A Pre-Amplification-Free Modular Dual-CRISPR System for Enhanced Pathogen Detection Sensitivity 1.00
Allosteric Regulation of Spherical Nucleic Acid for Facile Discrimination of Patients with Different Heart Failure Severity 1.00
Time-Lapse Deep Learning for Single-Cell Subcellular Structural Phenotypic Antimicrobial Susceptibility Testing 1.00
Ultrahigh-Power Sonicator Lysis Enables Deep Proteomic Profiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery 1.00
Rapid Bacterial Identification and Antimicrobial Susceptibility Testing Directly from Urine Samples via an Asymmetric Polymerase Chain Reaction-Cas12a Platform 1.00
Electrochemical Biosensing Platform Based on MOF Carrier Signal Probes and CRISPR/Cas12a Cleavage for Sensitive Detection of MicroRNAs 1.00
Single-Cell Super-Resolution Quantification of Oxidative DNA Damage via Aptamer-Assisted DNA-PAINT 1.00
Amplification-Free CRISPR-Cas System Integrated Centrifugal Digital Microfluidic Platform Developed for Multiplexed Respiratory Pathogen Nucleic Acid Analysis 1.00
Aggregation-State Engineered Melamine-Carbon Dots: Ultrasensitive Ethanol Quantification for Diagnosing and Classifying of Auto-Brewery Syndrome 0.81
Deep Learning-Decoded Raman Spectroscopy for Hour-Scale iPSC Pluripotency Assessment via Lipid–Protein Biomarkers 1.00
Adjuvant Tracer Strategy Combined with a Portable Steam Penetration Gas Membrane Separation Device for Peroxynitrite Detection 1.00
Aptamer-Gated Organic Photoelectrochemical Transistor Biosensor Based on a TiO2-Embedded Vertically Ordered Mesoporous SiO2 Film for Sensitive Detection of Carcinoembryonic Antigen 1.00
Spatially and Multivalent Matched Neutralizing Aptamer-Based DNA Nanostructure Alleviates Shiga Toxin Type 2 Infection 1.00
The Dual Nondestructive Amplification Strategy Realizes the Ultrasensitive Detection of Soluble TRAIL in Human Plasma 1.00
Deep Learning-Enabled Real-Time Single-Shot Refocusing of Microwell Array for Digital Melting Curve Analysis 1.00
Field-Deployable Photoelectrochemical Biosensor Using Atomically Defect-Engineered Heterojunction for Ultrasensitive Microcystin-LR Monitoring via Aptamer-Mediated Fe–S Conduction 1.00
The Cu Nanocluster-Sensitized and Filter-Concentrated Strategy for Rapid and Ultrasensitive Naked-Eyed Colorimetric Detection of Pathogens 1.00
A CRISPR-Cas12a Fluorescent Aptasensor for Point-of-Care Drug Concentration Detection: A Synergistic Regulation by DNA Aptamer and RNA Blocker 1.00
Engineered Nanobodies-Based Sandwich-Competitive Immunoassay Broadens the Detection Range for Aflatoxin B1 1.00
Programmable Fluorescent RNA with a Catalytic Hairpin Assembly System Enables Label-Free Monitoring of MicroRNA in Living Cells 1.00
Photoresponsive HOF-Based Platforms for Large Language Model-Assisted Multimodal Diagnosis of Metabolic Diseases 1.00
AI-Enhanced Lateral Flow Assay Enables 3-Minute Quantitative Detection with Laboratory-Grade Accuracy 1.00
An Ultrasensitive and Robust CircRNA Nanobiosensor via Magnetic Control Depuration and Catalytic Hairpin Assembly Cascade Amplification for Clinically Accessible Liquid Biopsy 1.00
Ultrasensitive Multiplexed Detection of Protein Biomarkers via Aptamer-Driven T7 RNA Polymerase Amplification 1.00
Automated Microchannel Resistance Readout of Immunorecognition via Programmable Nuclease Mediation for On-Site Biosensing 1.00
Immuno-RAFT Fluorescence Array Sensing for High-Throughput Analysis of CD81 Protein 1.00
Digital Microfluidic Platform Based on Printed Circuit Board for Affinity Evaluation of Mertansine Aptamers 1.00
One-Step, Signal-On, and Modification-Free Electrochemical Sensing Platform Based on Aptamer Switch Hydrogel 1.00
Allosteric Genetically Encoded Dual-Color Fluorogenic RNA Biosensor Simultaneously Illuminates miRNA and Its Precursor 1.00
Bifunctional Fluorescence Aptasensor Based on Target-Induced Strand Displacement Enables Simultaneous Detection of Dopamine and Serotonin in Multiple Body Fluids 0.90
Programmable Hairpin Argonaute–Nanopore Detection System for Multiplex Mycotoxin Analysis 0.86
Dual-Gate Carbon-Based FET Trace Gas Sensors: Enhancing Sensitivity through Work Function Modulation 1.00
Arginine-Rich Gold Silver–Nanoprobe for Rapid Virus Imaging and Real-Time Tracking in Infected Live-Cells 1.00
Trace Detection of Staphylococcal Enterotoxin B Based on Hydrogen-Terminated Diamond Solution-Gate Field-Effect Transistor 1.00
StratoLAMP-2: A Microfluidics-Free, Deep-Learning Platform for Multiplex Digital Molecular Diagnostics 1.00
A Microfluidic Colorimetric Biosensor Integrated with Water-Soluble Nonwoven Fabrics for Collection and Detection of Bacterial Aerosols 0.91
Dual-Polarity Switching Photoelectrochemical Biosensor Based on Z-Scheme Bi2S3/Bi2WO6 Heterojunction for Clinical Thalassemia Screening: Cascade Signal Amplification via 3D DNA Walker and Target Recycling 1.00
Flow-LAMP: Label-Free Digital LAMP Using Scatter-Based Flow Cytometry on Vortex-Generated Polydisperse Gel Beads 1.00
AI One-Click-Processing-Assisted Ratiometric RTP Paper-Based Sensor Array for the Rapid Discrimination and Detection of Mixtures of Oxolinic Acid and Flumequine 1.00
Ultrafast Detection of Small Molecules Using a U-Shaped Transmission Terminal and Straight Plasmonic Sensing Region Fiber Probe Biokinetic Platform: A Case Study of Label-Free Hcy Detection via Indirect Competitive Immunoassay 1.00
Machine Learning-Enhanced Analysis of miRNA Biomarkers for Accurate Breast Cancer Diagnosis Using DNA Seagrass 1.00
Critical Factors Affecting Digital PCR Quantification Accuracy in HBV DNA Reference Material for In Vitro Diagnostics 1.00
IDSP-IA: Immunotriggered Double Stem-Loop Probe-Mediated Isothermal Amplification for Attomolar Protein Quantification 1.00
Monitoring Chemotherapeutic Drugs Release from the Single Core–Shell Nanocarrier at a Monolayer Graphene-Based Total Internal Reflection Imaging Platform 1.00
Broad-Spectrum Aptamer Selection of Challenging Retronecine-Type Hepatotoxic Pyrrolizidine Alkaloids for Biosensor Construction 1.00
CRISPR-Programmed CuO Nanocatalyst Release for Ultrasensitive Detection of Pathogens in Sterile Body Fluids 1.00
Graphene Oxide Nanofluidic Ion Channels with Two-Gene Rolling Circle Amplification for Ultrasensitive and Specific Detection of SARS-CoV-2 1.00
Machine Learning-Assisted Terahertz Metagrating Biosensor for Label-Free Bacterial Identification Based on Spectral Fingerprinting 1.00
A Composite Hydrogel for Simultaneous SERS Detection of Glucose Concentration and Drug Therapy on Chronic Wound Surfaces in Diabetes Mellitus 1.00
A Dual-Response Quantum Dot Biosensor for Viral Protease and Nucleic Acid Detection 1.00
Glycan-Evoked Silver Deposition for Highly Sensitive Electrochemical Assay of Anti-dsDNA Antibodies 1.00
Peptide-Conjugated Dual-Photoelectrode Platform for Enhanced Anti-Interference Photoelectrochemical Cytosensing 1.00
One-Pot and Enzyme-Free Analysis of mRNA Vaccines Based on a Double Amplification System Featured by Adjustable Structure MNAzyme 1.00
Palindrome-Mediated Isothermal Cascade DNA Amplification and Effortless Nanosignal Transduction for One-Pot and Ultrasensitive miRNA Sensing 1.00
Breath Analysis Based on Advanced Photoinduced Charge Transfer Resonance-Assisted Strategy for Oxidative Stress Monitoring 1.00
Organic Photoelectrochemical Transistor/Visual Sensing Platform Based on CS/MCS Schottky Heterojunction and CRISPR/Cas12a-Driven Triple-Modal Synergistic Signal Amplification 1.00
Field-Deployable Immuno-Solid-Phase Microextraction Coupled with Photothermal Imaging for Rapid Pathogen Surveillance in Environmental and Clinical Matrices 0.71
3D-Printed Array Helical Monolithic Column Chip with Hierarchical Porous Structure for High-Throughput ICP-MS Analysis of Trace Rare-Earth Elements 1.00
Background-Free Rolling Circle Amplification for SERS Bioassay Using a Chimeric Hairpin-Integrated CRISPR/Cas12a System 1.00
Programmable Dual-Phase Electrochemical Biosensor Combines Homogeneous CRISPR/Cas12a Activation with Interfacial Poly-G Signaling for miRNA-21 Detection 1.00
Smart Lateral Flow Strip Biosensor for Visual and Portable Sensing of Antibiotic Residues Based on Cascaded Logic Circuits and DNA Biocomputations 1.00
Ligand Engineering-Based High-Efficiency Photothermal Sensors Powered Sensitive Lateral Flow Immunoassay Platform 1.00
Thioflavin T Is a More General and Less Interfering Probe for Aptamer Binding Assays Than SYBR Green I 0.17
Metabolite Fusion between Breath and Blood Enables More In-Depth Understanding of the Endogenous Metabolome 0.82
High-Affinity Aptamer Selection for Microbial Transglutaminase and Application in Colorimetric–SERS Dual-Mode Detection 1.00
Dual-Probe Strategy-Enabled Multiplex Photoelectrochemical Sensor for Highly Sensitive Screening of Diabetes and Related Complications 1.00
Assessment of Nanoplastic-Induced Disruption in Cellular Glutathione Metabolism Using a Bubble-Assisted Photothermal Capture SERS Sensor 1.00
Intelligent Visualization of Single Microbead Bubbling Enables Attomolar Protein Quantification 1.00
Investigation of Characteristic Volatile Organic Compounds in Esophageal Cancer Organoids by Mass Spectrometry 1.00
One-Pot Rlock-Mediated CRISPR/Cas12a-Driven RCA Cycle for Rapid and High-Sensitive APE1 Detection 1.00
Multiple Loci DNA Methylation Profiling for Rapid Colorectal Cancer Diagnosis Based on a Smartphone-Integrated Microfluidic Biosensing Platform 1.00
In Situ Plasmonic Gold Staining-Boosted Paper Test Kits of Human Albumin for Urinary Healthcare Monitoring 1.00
Assessing the Activity of Single Bacteria through Extracellular Recording of the Dynamical Extrusion of Protons 1.00
“Bio-inspired Nanoeye” Localizes Potentiated Antibody Binding Capacity for Driving Salmonella typhimurium Detection 1.00
Construction of a Self-Enhanced Fluorescent Aptasensor Based on Lanthanide Ligand Self-Assembly and Catalytic Hairpin Assembly for Highly-Sensitive Detection of Anatoxin-a 1.00
CRISPR/Cas12a-Mediated Electrochemical Aptasensor for Simultaneous Determination of Alzheimer’s Disease Biomarkers in Human Blood 1.00
CRISPR/Cas12a-Mediated Rolling Circle Amplification for the Development of Liquid Crystal-Based Sensors 1.00
Acryloyl Gelatin as Polymer Additive to Droplet Digital LAMP for DNA Quantification 0.83
Spatially Layered Dual-Porous Nanohybrids Enabling a Colorimetric-Fluorometric-Catalytic Continuous Gradient Signal Response for High-Performance Immunochromatographic Diagnosis 1.00
Single-Cell Detection of Circulating Tumor Cells by a Proximity-Enabled Singlet-Oxygen Chemiluminescence Assay 1.00
Advancing Microfluidic Photoelectrochemical Aptasensing Platform with Photogenerated Carrier Regulation for Protein Biosynthesis Inhibitors Detection 0.94
Dual DNAzyme-MoS2/GDY Catalytic Assembly Enables Smartphone-Based Multiplex Detection of Sugarcane Pokkah Boeng Pathogens at Sub-Femtomolar Levels 1.00
Broad-Specificity Immunochromatographic Strip Assay for Alkaloids: From Hapten Design to Antibody Recognition 1.00
A Finger-Actuated Microfluidic System for Point-Of-Care Detection of SARS-CoV-2 and Influenza A 1.00
Ultrasensitive Detection of Nucleic Acid and Protein at Ambient Temperature by Using an Engineered CRISPR-Cas12a-Based Digital Assay 1.00
Self-Sustaining miRNA Amplification Diagnostics via Catalytic Hairpin Assembly and Split Activator-Initiated CRISPR/Cas12a Hybrid Feedback Circuit with Target Regeneration and Recycling 1.00
Integrating Fluorogenic DNAzymes with Photonic Crystals for Bacterial Detection on a Microfluidic Biochip 1.00
Selective Interfacial Assembled Asymmetric Porous Nanomotors as Maneuverable Labels for Boosting Capture and Ultrasensitive Detection 1.00
Reusable Visualization Photoelectrochromic Molecularly Imprinting Chip Lower-Voltage Driven by Photoassisted Fuel Cells 1.00
A Selective and Sensitive Method for Colistin Detection by G-Quadruplex Ligand Competition 0.81
Novel Self-Powered Biosensor Based on Highly Efficient Cosignal Accelerator and Multiple Signal Amplification Strategies toward Ultrasensitive miRNA-141 Assay 0.89
Mitochondria-Targeted Polymeric Liposomes for Pre-miRNA Imaging and Gene Therapy 1.00
Multifunctional Amyloid-Like Porous Nanofilm-Decorated Transistor-Based Biosensor for Accurate Detection of Alzheimer’s Disease Biomarker 1.00
Hollow Cu/Zn-MOF@Au/Ferrocene Nanoarchitectures: A Universal Leap from Colorimetric to Dual-Mode Colorimetric/Electrochemical Lateral Flow Assays 0.88
Synergistic Catalysis in Ni/Pt Dual-Atom Systems for Dynamic Sweat Metabolite Tracking 1.00
EDTA-Masked Tl+ Detection Using a Pair of Non-G-Quadruplex Aptamers with Opposite Fluorescence Responses 0.50
Benzonase-Based Closed-Tube DNA Degradation Strategy for Elimination of Nucleic Acid Contamination 1.00
Ultrasensitive Quantum Weak Measurement Biochemical Sensor via a Porous Anodic Alumina Nanostructure 1.00
Condensation-Enhanced DNA Nanotracker on Facilitating Spatially Selective Intracellular miRNA Profiling and Robust Gene Therapy/Chemotherapy 1.00
Ru(phen)32+-Sensitized GaN-Gated Organic Photoelectrochemical Transistor for Sensitive and Selective Detection of Human Papillomavirus DNA 1.00
Attomolar Nucleic Acid Detection Using CRISPR Enhanced Phase-Sensitive Surface Plasmon Resonance Imaging 0.98
Glycosylation-Engineered Chitosan Bioelectronic Interfaces for P. aeruginosa Gradient Analysis 1.00
Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae 1.00
Ultrasensitive Label-Free Biomarker Detection Utilizing a Large-Core Biconical Fiber-Embedded Optofluidic Biochip with Optimized Optical Architecture and Multimodal Signal Amplification 1.00
Hyperbranched Rolling Circle Amplification Enabled Nanopore Sensing Platforms for Ultrasensitive Multiplex MicroRNA Detection and Logic-Gated Molecular Diagnostics 1.00
Fully Integrated Wearable Biosensor for Multiple iIn Situ/i Phosphorylated Tau Protein Detection 1.00
A 3D Printed Meridian-Arrayed Microfluidic Device for Dual-Physical Fields Induced Highly Efficient Intracellular Delivery 1.00
Temperature-Modulated SERS Fusion Enables Accurate Diagnosis of Clinical Fungal Pathogens 1.00
Sensitive Detection of Exosomal Biomarkers via a Drop-Shaped Porous Microfluidic Chip for Potential Diagnosis of Alzheimer’s Disease 1.00
A Monolith-Based μHPLC-SERS Integrated Microplatform Featuring Mg2+-Regulated Dual-Capture Mechanism for Real-Time Online ATP Monitoring 1.00
Simultaneous Bioelectrochemical Detection of Nitrate and Nitrite with a Whole-Cell Hydrogel Electrode 0.94
One-Step Detection of RNA in Small Extracellular Vesicles from Plasma for Diseases Diagnosis by a Multisatellites@planets Molecular Imprinting Platform 1.00
A Novel Hand-Held Spinning Platform with Centrifugal Microfluidics for Rapid, Cost-Effective Urinary Total Protein Detection at the Point of Care 1.00
Enhancing Classification Robustness in Real-Time Digital PCR via Amplification Curve Regulation and Clustering Analysis 1.00
Prussian Blue Nanozyme-Based Dry-Dipstick Reflectometry for Multiplex Detection of Low Molecular Weight Metabolites 1.00
Hapten Design and Antibody Production for a Highly Sensitive Broad-Spectrum Immunoassay for Detection of Seven Organochlorine Pollutants in Soil and Oilfield Chemicals 1.00
Real-Time Fluorescence Aptasensor Based on Programmable Switch-Coupled Exponential Amplification Transduction for Ultrasensitive and Specific Vibrio parahemolyticus Determination 1.00
Selection of Aptamers Targeting Different Epitopes of Recombinant Thyroid-Stimulating Hormone Receptor Protein 1.00
Real-Time Detection of Trace Breath Isoprene Based on Circular Domain Spectral Reconstruction Filtering Combined with Convolutional Neural Network 1.00
On-Site Therapeutic Drug Monitoring for Program Death-1 Antibody Using a Quantum Dot Nanobeads-Based Lateral Flow Immunoassay 1.00
Small-Molecule Binding-Guided Nucleic Acid Amplification and Its Ultrasensitive Electrochemical Detection of Aflatoxin B1: A Split Aptamer Ligation Chain Reaction via Click Chemistry 1.00
Liquid-Phase Barrier Modified Nitrocellulose Membrane: A Strategy for Boosting Chemiluminescent Detection in Lateral Flow Assays 1.00
Precise Determination of CpG Methylation through Entropy-Driven Cascade Circuit 1.00
Slice-Inference-Assisted Lightweight Small Object Detection Model for Holographic Digital Immunoassay Quantification 1.00
Studying the Effect of Receptors Clustering on Hyaluronic Acid Binding with CD44 and the Cell Entry of Hyaluronic Acid Targeting Nanodrugs at Single Molecule/Particle Level 1.00
A Woundplast of Hydrogel Microneedles with In Vivo ATP-Responsive Therapeutic Logic for Bacteria-Infected Wound Healing 1.00
Self-Powered and Sensitive Assay of Caspase-3 Activity Based on an Ultralarge Photocathodic Current Amplified by Polydopamine Modification and a CdIn2S4/CdS Heterojunction Photoanode 1.00
Mutually Activated Dual-Exponential Amplification DNA Machine Enhances Robust CRISPR/Cas12a Feedback Propagation for Ultrasensitive miRNA Detection 1.00
Elimination of Carryover Contamination during Nucleic Acid Amplification Based on Damaged Base Excision by DNA Repair Enzymes 1.00
Split G-Quadruplex-Integrated CRISPR-Cas Biosensor for One-Pot, Signal-On Visual Detection of Pathogen Nucleic Acids 1.00
Application of Non-G-Quadruplex Hemin Aptamers to Hemin Detection and Heme Oxygenase 1 Activity Evaluation via Spatial Conformational Constraint 1.00
Construction of a Near-Infrared-Light-Triggered Dual-Signal Biosensing Platform for Microcystin-RR Detection Based on the Z-Type Heterojunction of Bi2S3/In(OH)3 1.00
High-Output Droplet Electricity Generator for Intelligent Self-Powered Biochemical Analysis 1.00
An Artificial Intelligence Olfactory-Based Diagnostic Model for Parkinson’s Disease Using Volatile Organic Compounds from Ear Canal Secretions 1.00
Reversible Ligand–Receptor Interaction-Induced “Tango”-like Dancing of Nanodisks on Living Cell Membrane 1.00
Pheno-Molecular Testing Enabled by Multiplex Droplet Digital PCR for Rapid and High-Content Detection of Carbapenem-Resistant Enterobacterales 1.00
High-Performance Selection of Small-Molecule Nucleic Acid Aptamers and Their Applications 0.95
A Rapid Electrochemical DNA Biosensor for Serum Uric Acid Using the Pre-equilibrium Binding Mechanism 1.00
Cascade Signal Amplification of Time-Resolved Fluorescence Immunoassay through Enzyme Catalysis Coupled with Dissolution Enhancement 1.00
Property Characterization of Leucine-Integrated Oligonucleotide 1.00
Development of a Cell Membrane-Anchored Aptamer Sensor for IL-2 Detection In Situ 1.00
Breaking the Sensitivity-Specificity Trade-Off: A Nanoconfined Dual-DNA Aptamer Synergy Strategy 1.00
Reconfiguration/Immobilization “Dual-Free” Self-Powered Multiplex Photoelectrochemical Strategy for Dual Magnetic Bead-Mediated Dimension Differentiate Type Complex Sample Assay 1.00
Digital SERS Nanostructured Platform for Amplification-free Single-Molecule DNA Detection and Pre-Symptomatic Diagnosis of Kiwifruit Soft Rot 1.00
Pericyte Biomarkers for Ischemic Stroke: Potential and Prospects 1.00
Highly Sensitive Detection of Let-7a in Different Tumor Cells Based on a Dual Cascade Signal Amplification Strategy 1.00
Dual-Amplification CRISPR Biosensor for Ultrasensitive miRNA Detection: A Powerful Tool for Cancer and Immune Monitoring 1.00
Lattice Substitution Induced Fast Charge Transport in Integrated and Flexible Organic Photoelectrochemical Transistors for Portable Sensing 0.86
Fluorescence Aptasensor for sST2 Detection Using In Vitro Selected Aptamers 1.00
Investigation of Body Fluids Intervention Impact on Aptamer Screening via Capillary Electrophoresis 1.00
Assembling ″Balloon-String″ Colorimetric Probes through Click Chemistry and Hybridization Chain Reaction for Dual-Signal Amplification in Aptamer-Based Lateral Flow Assays 0.89
S9.6 Antibody-Mediated Bivalent Capture Biosensor Using Vacuum-Assembled HCR Amplifier for One-Pot, Record-Fast and Ultrasensitive Detection of Nucleic Acid 1.00
Single-Tube Multiplex Detection of High-Risk HPV Subtypes Utilizing Lanthanide Nanoprobes 0.80
Phosphorothioate-Modified Hairpin G-Triplex Reporter-Assisted Split CRISPR/Cas12a-Powered Biosensor for “Turn-On” Fluorescent Detection of Nucleic Acid and Non-Nucleic Acid Targets 1.00
RH-RPA: A Rapid and Highly Sensitive Assay for Nucleic Acid Detection Based on RNase HII Combined with Recombinase Polymerase Amplification 1.00
S9.6 Antibody-Mediated Wireless Portable Biosensor with Multiple Affinity Enhancements for Comprehensive Detection of Nucleic Acid in Serum 1.00
35 33.70
A NIR-Gated Nanogenerator Enables Low-Dose Nitric Oxide-Potentiated Phototherapy 1.00
Rapid Discrimination of Single-Virus Entry Pathways via a Bioorthogonal Activatable Fluorescent Probe 1.00
The Precise Modulation of Probe Effective Charges by Debye Length for Enhancing Performance of Aptamer–FET Biosensors 1.00
Remote Molecule Activation in Living Mice Triggered by Therapeutic Ultrasound 1.00
Near‐Infrared‐Activated Multiphoton Photocatalytic System for Synergistic Therapy via CO Generation and •OH Production 1.00
Manganese-Coordinated Polyvalent Aptameric System (COMPASS) Enables DC-Targeted mRNA/Mn2+ Co-Delivery for Cancer Immunotherapy 1.00
Thiourea-Functionalized Ionizable Lipids Enable Systemic mRNA Delivery to Secondary Lymphoid Organs and Dual-Modal Lymphatic Metastasis Imaging 1.00
A Label-Free Phosphate-Transfer DNAzyme for the Cost-Effective Point-of-Care Detection of Influenza Virus 1.00
CO/H2S Dual Prodrugs Activated by Proximity-Enhanced Chemiexcitation for Suppression of Tumor Growth and Metastasis 1.00
Point-of-Care Diagnosis of Respiratory Viruses at Single-Nucleotide Resolution with an Autocatalytic Rolling Circle Amplification System 1.00
Harnessing Deaminated DNA to Modulate mRNA Translation for Controlled and Sequential Protein Expression 0.10
Small-Molecule Probes Enhance in Vivo Field-Effect Transistor-Based Biosensing by Overcoming Debye Length Limitations 1.00
Bioorthogonal RNase L Recruitment Enables Targeted Inducible Degradation of SARS-CoV-2 RNA 1.00
Tungstotellurate(VI)-Based Nanocomposite Inhibits Breast Cancer Proliferation and Metastasis by Enhancing Cuproptosis and Apoptosis 1.00
Zinc‐Coordinated Lipids: Facilitators for Enhanced mRNA Delivery Efficacy 1.00
Single-Cell Antimicrobial Susceptibility Testing via Stimulus-Responsive Resonance Raman Scattering Imaging 1.00
Ultrasensitive Digital Immunoassay in Homogenous Format by Singlet‐Oxygen Activated Up‐conversion Luminescence 1.00
Stabilizing Cu3+ Active Center by Intramolecular Electron Transfer for Boosting Complete Glucose Electrooxidation 1.00
A Reusable Substrate for Capture and Red Light‐Responsive Release of Circulating Rare Cells with High Cytoactivity 1.00
Individual Virus Detection by Peptide–Gold Nanocluster-Assembled Artificial Binder 1.00
A Versatile DNAzyme-Amplified Protease-Sensing Platform for Accurate Diagnosis of SARS-CoV-2 and Reliable Classification of Colorectal Cancer 1.00
Sub‐1 nm CuO‐Phosphomolybdic Acid Nanosheets for Ultrasound‐Controlled Pyroptosis Activation and Tumor Immunotherapy 1.00
Engineering Neural Stem Cells with Micropatches for Improved Therapy of Traumatic Brain Injury 1.00
Dual‐Responsive Ultrathin Polymersomes with Reversible Transitions on Acidochromism and Fluorochromism Performances for Multiple Information Encryption 1.00
Functional Dendrimer Nanogels for DNA Delivery and Gene Therapy of Tumors 0.63
Supramolecular Polyanions as Effective Interphase Layers for Anode‐Free Lithium Metal Batteries 1.00
Surface Engineering of Hollow Microreactors with Catalytic Nanobrushes for Orthogonal Tandem Catalysis 1.00
Stimuli‐Responsive Catenane‐Branched Dendrimers with Tunable Dimension for Reversible Guest Binding 1.00
Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry 1.00
Erasable Fluorescence Imaging Technology Enables Continuous Tracking for Identical Living Cells 1.00
An Engineered Multivalent TMV Nanodisk Platform for Modulating Integrin Clustering and Cell Signaling 1.00
DNA Nanotubule‐Based Nanodevices with ATP‐Responsive Gating for Direct Cytosolic Delivery of Nucleic Acids and Proteins 1.00
AM-DMF-ddRPA: an All-in-One Digital Microfluidic Platform for Rapid and Automatic Digital Nucleic Acid Analysis 0.98
From Theophylline to Adenine or preQ1: Repurposing a DNA Aptamer Revealed by Crystal Structure Analysis 1.00
Precise PBAEs: A Highly Efficient Single‐Molecularly Defined Gene‐Delivery System 1.00
1 0.01
Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau scpPET/scp Clocks 0.01
1 0.94
TBXAS1 deficiency causes autoinflammation responsive to IL-6 inhibitor 0.94
6 5.13
Performance enhancement of Love wave sensor via a cost-effective and robust dual-layered waveguide 0.91
Rapid malaria detection using a spin Hall magnetoresistance sensor 0.22
Early diagnosis of Parkinson's disease by highly sensitive monitoring of glucose using an atomic-level defect-enriched MoS2/Au SERS sensor enabled by LSPR-PICT synergy 1.00
CoSe2 nanoparticles catalyzed the formation of Cu-BTC polyhedral nanoframes enabling biosensing of endogenous opioid peptides 1.00
Label-free and ultra-low concentration detection of gastric cancer biomarker miRNA 106a using In-Sn-Zn-O thin-film transistor biosensor 1.00
A CIPS-based negative capacitance field-effect transistor biosensor with extended-gate structure 1.00
2 2.00
Single‐cell transcriptomic analysis on multi‐subtypes of idiopathic inflammatory myopathy reveals pathological hallmarks associated with stromal stem and immune cells in damaged skeletal muscles 1.00
Mesenchymal Stromal Cell Therapy Alleviates Lupus Nephritis Through Inhibiting Caspase‐4/5/11‐mediated Noncanonical Pyroptosis in Macrophages 1.00
3 0.99
Nucleoplasmic ZNF467 condensates boost hematopoietic stem cell engraftment via ICAM1-mediated mechanical reprogramming 0.83
Marstacimab Prophylaxis in Hemophilia A/B Without Inhibitors: Results from the Phase 3 BASIS Trial 0.11
Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study 0.05
3 2.01
iIn vivo/i self-assembled siRNAs ameliorate neurological pathology in TDP-43-associated neurodegenerative disease 1.00
Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer’s disease spectrum 0.01
Interleukin-17B is a new biomarker of human muscle regeneration in dystrophinopathies 1.00
1 1.00
Lipid Nanoparticle–Encapsulated mRNAs Encoding Tumor-Specific Toxin Proteins Selectively Target Cancer Cells and Stimulate T-cell Infiltration 1.00
9 6.38
2'3'-cGAMP-induced membrane shearing promotes broad antiphage immunity 1.00
p53 safeguards chemical reprogramming of human somatic cells toward pluripotency 1.00
Fertilization triggers early proteomic symmetry breaking in mammalian embryos 0.18
RNA innate immunity constitutes a barrier for interspecies chimerism 0.24
Fibroblast bioelectric signaling drives hair growth 0.85
A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells 0.96
A mechano-resistance mechanism in skin adapts to terrestrial locomotion 1.00
An alternate receptor for adeno-associated viruses 0.27
Senescence-resistant human mesenchymal progenitor cells counter aging in primates 0.89
8 6.05
Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo 1.00
Preservation of chondrocyte microspheroids by local sustained hydrogen supply improves osteoarthritic cartilage repair 1.00
Dysplastic epithelial repair promotes the tissue residence of lymphocytes to inhibit alveolar regeneration post viral infection 1.00
3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy 1.00
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling 0.05
Signaling reprogramming via Stat3 activation unravels high-fidelity human post-implantation embryo modeling 0.98
Chemical reprogramming of human blood cells to pluripotent stem cells 1.00
Human airway submucosal gland organoids to study respiratory inflammation and infection 0.02
26 24.29
ROS-accelerated quinone formation from gossypol in a dendritic AIE polymer enables synergistic type I photodynamic therapy and chemotherapy 1.00
A dual-mode aptasensor integrating ratiometric fluorescence and colorimetry for on-site Cu2+ detection 1.00
Perovskite-gold shell composite nanoprobe for trimodal lateral flow immunoassay detection of SARS-CoV-2 antibodies 1.00
Functionalized nanopipettes for pH-gated single cell DNA delivery 1.00
A DNAzyme-induced disposable strip biosensor for visual detection of trace levels of UO22+ in remote areas 1.00
Photoelectrochemical assay for E. coli based on CBT–Cys-guided rolling circle amplification 1.00
Coupling calcination with sulfidation strategy to fabricate a hydrophilic bimetallic transition nanozyme for boosting antibacterial efficiency 1.00
CRISPR-coupled triple cascade amplification for simultaneous lateral flow detection of Mycoplasma pneumoniae and H1N1 1.00
Fluorescent protein display on cellular mimic enables rapid and accurate identification of natural killer cell phenotypes 1.00
Intracellular biosensors by functional nanomaterial-integrated CRISPR technologies for real-time molecular sensing 0.25
Combining aptamers for thiamphenicol and chloramphenicol for detecting both antibiotics 0.17
Unraveling the mechanisms behind porous calcium phosphate ceramics-instructed osteoinduction: a systematic review 1.00
A pseudo-circular DNA walker-mediated electrochemical biosensor for sensitive detection of the apolipoprotein E4 gene 1.00
Epitope bias in antibody affinity assays arising from charge-dependent orientation in carbodiimide-mediated protein immobilization using β2-microglobulin as a model antigen 1.00
C–SiO2 hollow nanostructures by a pseudo-hard-template route for outstanding perfluorooctanoic acid removal 1.00
Nucleus-targeted protein delivery via lysine dendron conjugation 1.00
Rapid detection of antibiotics using self-developed electrochemical analyzer and sensor chip 1.00
Revealing the effects of the cell cycle on cellular uptake of nano-drugs at single particle level 1.00
Amino-modified high-surface-area radial-pore silica microspheres for efficient perfluorooctanoic acid removal 1.00
Single nanoparticle analysis-based CRISPR/Cas12 bioassay for amplification-free HIV detection 0.88
Ferrocene-functionalized COF-derived Fe single-atom dispersed N-doped porous carbon for enhanced electrochemical sensing of chloramphenicol 1.00
iS/i-Nitrosylated Au@COF nanohybrids for synergistic light-nitric oxide killing of bacteria 1.00
Extremes meet: changeover between pro- and antioxidant activities of Cu-based nanozymes 1.00
Stimuli-responsive peptide-based nanodrug delivery systems for tumor therapy 1.00
In situ enrichment and ultrasensitive analysis of interstitial fluid miRNA enabled by hydrogel microneedles coupled with DNA-gated metal–organic frameworks 1.00
iTwo birds with one stone:/i colorimetric and photothermal dual-mode biosensor based on CoOOH nanorings for detecting β-galactosidase activity and iEscherichia coli/i 1.00
10 8.42
Time-ordered-expression mRNA (TOE mRNA) for melanoma RNA vaccines 1.00
Atomic Ce sites promote a four-electron pathway of Pt as NADH oxidase mimics for in situ coenzyme regeneration 1.00
A preliminary profile of RNA bound on the cell surface 1.00
A simple epoxide modification strategy to construct amino-functional poly(2-oxazoline) mRNA delivery vectors 1.00
Multi-dimensional analysis of single particles with sequential dual-nanopipette sensors 1.00
A general transition metal binding aptamer following the Irving–Williams series 0.36
Multi-site orbital coupling in Ru-based high-entropy alloy-enabled hydroxyl spillover for enhanced peroxidase-like activity 1.00
Aptamer single-molecule dispersion on single-atom anchoring sites for high-selectivity in vivo detection 1.00
Multifunctional cerium-based nanozymes as moonlighting protein mimics for atherosclerosis diagnosis and therapy 1.00
Highly selective DNA aptamer sensor for intracellular detection of coenzyme A 0.06
1 0.13
Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial. 0.13
2 2.00
Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation 1.00
Proteomics-based multi-omics identifies the roadmap of transcription-translation-protein dynamics in planarian regeneration 1.00
6 6.00
CuO Nanoparticles Trigger Cuproptosis-Linked Mitochondrial Damage and Gut Microbiota–Metabolome Disruption in Zebrafish 1.00
Machine learning frameworks for predicting pulmonary cell toxicities induced by metal ions in the atmosphere 1.00
Gestational exposure to micro- and nanoplastics leads to poor pregnancy outcomes by impairing placental trophoblast syncytialization 1.00
A sensitive colorimetric immunosensor for clozapine, norclozapine, and clozapine-N-oxide simultaneous detection based on monoclonal antibodies preparation with homogeneous cross-reactivity☆ 1.00
Amplified toxic effects of nanoplastic composite norfloxacin on liver cells in mice: Mechanistic insights and multiscale evaluation 1.00
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice 1.00
16 15.66
Deposition Patterns of Carbon Black Nanoparticles in Pulmonary Lobes and Airway Generations: Implications for Lung Remodeling 1.00
MXene-Based Nanoconfined Ion Channels for Ultratrace Detection of Short-Chain Per- and Polyfluoroalkyl Substance Trifluoromethanesulfonic Acid and Its On-site Application 1.00
Usage Analysis and Multicriteria Alternative Assessment of Alternative Plasticizers: Are They Safer Alternatives? 1.00
Method Development and Sensitivity Optimization Paradigm for One-Step RPA-CRISPR/Cas12a Rapid Detection of the Hard-to-Amplify Gene blaNDM 1.00
Biotransformation of Atmospheric-Aged Metal-Sulfide Nanosheets in Respiratory Tract Fluids Potentiates Ferroptosis toward Alveolar Macrophages 1.00
The Analysis and Assessment of Exhaled VOCs in Adults under Ambient Ozone Exposure 1.00
Polysaccharide Hydration Networks Suppress Pyrophoricity and Preserve Reactivity of Iron Nanoparticles for On-Demand Environmental Remediation 1.00
Highly Sensitive Bioactivity Assessment of Thyroid-Disrupting Chemicals in Human Samples across the Entire Exposome Landscape 1.00
Deep Learning-Enabled Unbiased Precision Toxicity Assessment of Zebrafish Organ Development 1.00
Advanced Breathomics Reveals Human Absorption of Exogenous Volatile Organic Compounds 1.00
ZnO-NPs Neurotoxicity to iCaenorhabditis elegans/i: Disorders of Fatty Acid Synthesis and Glutathione Metabolism 1.00
Portable Real-Time Detection of Hydrogen Sulfide in Wastewater Using a Pt/CrWN2-Based Electrochemical Sensor 1.00
Ultrasensitive Nanofluidic Detection of 17β-Estradiol in Natural Water by DNA Circuit-Mediated Hyperbranched DNA Nanowire Dual-Signal Amplification 0.91
Continuously Responsive Surface-Enhanced Raman Scattering Sensors for Long-Term On-Site Free Chlorine Monitoring in Aquatic Environments 0.92
ExposomeX: Development of an Integrative Exposomic Platform to Expedite Discovery of the “Exposure−Biology−Disease” Nexus 0.83
Air Toxicity Surveillance across Thirteen Cities Using Rats 1.00
1 0.94
CD177+ neutrophils drive extracellular matrix remodelling and HGF-alpha release in ALPPS-induced liver regeneration 0.94
2 2.00
GPC3-based circular RNA vaccine suppresses hepatocellular carcinoma progression by activating adaptive immune responses. 1.00
Proenkephalin produced by neonatal T-bet+ Treg cells promotes periportal hepatocyte maturation. 1.00
1 1.00
CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo 1.00
5 5.00
Breaking the “Industrial Vitamin” Paradigm: La-N4 Single-Atom Sites Enable Highly Active Multicomponent Electrochemical Sensing in Tear Fluid 1.00
Biodegradable Ca-MOF Nanoplatform with Intracellular H2O2-Triggered CO Release to Augment Mitochondrial Ca2+ Overload for Synergistic Cancer Therapy 1.00
Polyethylenimine-Mediated Assembly of Dual-Emissive CsPbBr3@SiO2@EuW10 Composite Nanospheres for Ratiometric Detection of 2,6-Dipicolinic Acid 1.00
Fluorescent Microneedle Sensors Based on Tb3+@Hydrogen-Bonded Organic Frameworks for Real-Time Food Freshness Monitoring 1.00
Metal–Organic Framework-Based Self-Powered Chemodynamic Therapy Nanosystem: CaO2@PCN-222(Fe) and Its Mixed Matrix Membranes for Promoting Infected Wound Healing 1.00
2 2.00
The RING E3 ligase RLIM drives oxidative stress-induced stem cell dysfunction through MDM2-p53 signaling 1.00
Calcitonin gene-related peptide inhibits macrophage migration and differentiation via the GTPase Rap1 1.00
3 2.23
Prevascularized Bone Marrow-Derived Mesenchymal Stem Cell Sheets Promote Tendon-Bone Integration in Rotator Cuff Repair. 1.00
Comparative Efficacy of Surgical Versus Nonsurgical Management for Acute Achilles Tendon Rupture in a Novel Mouse Model. 0.83
Bezeotermin Alfa (rhBMP-6) Administration in Lumbar Interbody Fusion Surgery Using a Posterior Approach 0.40
2 1.71
Structure-guided and sustainable engineering silk sericin powder with improved storability, redissolution, and biocompatibility 0.71
Selenium-doped NiCo2O4 drives nanozyme innovation: new ideas in water disinfection 1.00
1 1.00
Effect of rhGM-CSF in promoting wound healing via macrophage immunomodulation 1.00
2 1.93
BM-derived mesenchymal stem cell microvesicles protect enteric neural precursor cells and alleviate diabetes-associated enteric neuropathy 1.00
Combined FXIII-C3 autoantibodies elicit bleeding and complement dysfunction in autoimmune FXIII deficiency 0.93
2 2.00
IFRD1 orchestrates hepatocyte metabolism and macrophage interactions to facilitate liver regeneration 1.00
Setd4-expressing cells drive regenerative recovery in chronic liver injury 1.00
41 35.87
Site-Specifically Modified Circular Ribonucleic Acid Serves as Multitarget miRNA Sponge with Low Immunogenicity 1.00
Diffusion-Mediated Synthesis of Durable High-Entropy Sulfide Nanocrystals: Le Chatelier-Driven and Electron Configuration Effects 1.00
Bioinspired Diffusion-Limited Silicification in Coacervate Assemblies Enables Smart Nanotoroids for Deep and Sensitive Tumor Penetration 0.85
Ultrasound-Activated Prodrugs for Tumor-Specific Immunotherapy 1.00
Unraveling the Role of Ionizable Lipid Isomerism in Modulating Lipid Nanoparticles for mRNA Delivery 1.00
Engineering Polymer–Lipid Integrated Nanoparticles with Quantitative Design Principles for Organ-Selective mRNA Delivery 1.00
Safe and Highly Efficient Lipid-Pro-Dexamethasone Nanoparticles for mRNA Delivery and Base Editing 1.00
FAP-Synergistic Organ-Targeted mRNA-LNP for Overcoming Delivery Barriers in Hepatic and Pulmonary Fibrosis 1.00
Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia 1.00
Electrochemomics Profiling Metabolic Dynamics in Biofluids 0.32
Aromatic Ionizable Lipids Enhance mRNA Delivery via Coordinating Multiple Mechanisms 1.00
Synchronous 3D-DNA Walking-Driven Dual-Color RNA Aptamers Lighting-Up for Label-Free and Attomolar Profiling of Multiple circRNAs in Breast Cancer 1.00
Mirror-Image L-DNA Aptamers Enable Stable In Vivo Dopamine Sensing 1.00
BODIPY-Doped Nanocarrier Engineering (BONE) Improves Bone Marrow mRNA Delivery by NIR-II Bioimaging Guided Screening 0.68
Tailoring Square-Shaped 2D Mesoporous Nanosheets via an Interface-Confined Anisotropic Assembly Strategy 0.82
Amino Acid Residue-Driven Nanoparticle Targeting of Protein Cavities: Surface Chemistry Dictates Binding Specificity beyond Size Complementarity 0.68
Evolution of Cross-Linking Aptamers for Long-Lasting Membrane Protein Labeling 1.00
Active Polymer-Templated Porous Metal Oxide Nanospheres with Tailored Single-Atom Modification for Olfactory Intelligence 0.87
Autonomous Exponential Amplification via Rolling Circle–DNAzyme Feedback Programming 0.86
Thioketal-Incorporated Biodegradable Lipid Nanoparticles Deliver mRNA to Ductal Epithelial Cells for Improved Pancreatic Cancer Treatment 1.00
Lipid Nanoparticle Chaperone with Redox-Adaptive Intracellular Microenvironment Modulation Potentiates the Potency of mRNA Vaccines 0.80
An O2-Independent Copper(II) Phototherapeutic Agent for Photoactivating H2O2 to Enhance Antitumor Immunotherapy 0.50
Hydrogen Bond-Assisted Two-Component Lipid Nanoparticles for Spleen-Specific mRNA Delivery 1.00
Glycolipids Substitute PEG lipids in Lipid Nanoparticles for mRNA Delivery 1.00
A General Synthesis Strategy for Alkali Metal Halide Nanosalts 1.00
Fluorinated Ionizable Lipids for Efficient Spleen-Targeted mRNA Delivery in Cancer Immunotherapy 1.00
Personalized Cancer-Specific Protein-Aptamer Corona for Orthogonal Multiplex Cancer Diagnosis 1.00
Targeted RNA Degradation via LipoSM-RiboTAC Nanoparticles: A Versatile Platform for Cancer Therapy 1.00
Computationally Aided Design of Ionizable Cholesteryl Lipids for Lipid Nanoparticles to Modulate Hepatic mRNA Accumulation 0.57
Spatial Conformation of Ionizable Lipids Regulates Endosomal Membrane Disruption 0.05
Strain-Promoted mRNA Transdermal Delivery by Lipoic Lipid Nanoparticles for Therapeutic Skin Genome Editing 0.92
Photochemical Generation of Peroxynitrite: Concurrent Inhibition of Glycolysis and Glutamine Metabolism for Enhanced Metabolic Therapy 0.75
mRNA-Based FRET-FLIM Imaging Platform for Quantifying Lipid Nanoparticle Endosomal Escape and Membrane Damage 1.00
Ultrasound-Activatable Lipid Nanoplatform for Region-Confined Innate Immune Stimulation and mRNA Vaccination Therapy of Cancer 0.86
Amplifying Engineered Bacterial Outer Membrane Vesicle Production Using Functional Peptidoglycan Inhibitors 0.35
Carbonate-Bearing Ionizable Lipids for mRNA Delivery to Splenic NK Cells 1.00
Ternary Interactions Balance Enabled Sequential Assembly toward the Synthesis of Hierarchically Mesoporous Metal Hydroxide Nanoparticles 1.00
Breaking Endosomal Barriers: Thiol-Mediated Uptake Lipid Nanoparticles for Efficient mRNA Vaccine Delivery 1.00
High-Throughput Multiplexed Quantification of Molecules by Aptamer Sequencing (Apt-seq) in Single Cells 1.00
Ultrasound-Triggered Activation of p-Azidobenzyloxycarbonyl-Based Prodrugs via Radical-Mediated Cascade Elimination 1.00
RNA Editing-Mediated Correction of TP53 Nonsense Mutations via Lipid Nanoparticle-Delivered Circular ADAR-Recruiting RNAs 1.00
2 1.88
Robust Artificial Spider Silk via Synergistic Cross-Linking of Slide-Ring and Covalent Bonds 0.88
Efficient Access to Functionalized Mesoporous Materials with Bicontinuous Morphologies via a Kinetic Approach 1.00
2 1.04
Aberrantly integrated adult-born immature neurons disrupt brain-wide networks during spatial memory processing 0.08
Associations between trajectories of plasma biomarkers for Alzheimer’s disease, brain structures, and cognitive function: a prospective cohort study in the UK Biobank 0.96
28 27.46
On-Demand Switching of a pH/ROS-Responsive Ce Single-Atom Nanozyme Spray for Infected Wounds 1.00
Evolution of Aptamer Materials Maps Exosomal Surface Proteins at the Nano–Bio Interface 1.00
Single Microbead Floating/Sinking-Enabled Digital Biosensing 1.00
Polyphenol-Engineered Bimetal Oxides Promote Stem Cell Differentiation via Immune Microenvironment Reprogramming 1.00
Mass Spectrometry-Assisted High-Throughput Discovery of Lung-Specific Lipid Nanoparticles for In Vivo Protein Delivery 1.00
Adhesive Conductive Hydrogel Interface for Noninvasive Electrochemical Sensing of Nitric Oxide in Plant Leaves and Fruits 1.00
Interfacial Electric Locking of the Aptamer Conformation for Accurate Liquid Biopsy Detection 1.00
Noninvasive Salivary Ketone Monitoring: A Ratiometric Pdot Biosensor toward Personalized Ketogenic Management 1.00
Encapsulation of RNA with DNA Six-Helix Bundle Nanostructures 1.00
Spatially Controlled DNA Hydrogel–MXCT Nanofluidic Biosensor for Noninvasive Iontronic Detection of Estradiol across the Menstrual Cycle 0.91
A Universal Framework Nucleic Acid Platform for Kidney-Targeted Delivery of Natural Bioactive Compounds 1.00
Targeted SERS Nanoparticle Accumulation on Bacteria Enables On-Site Accurate Vibrio Typing in 10 min with AI-Powered SERS 1.00
RNA Resolution in an Electric Double Layer Generated by Metal–Organic Frameworks 0.95
Single-Atom-Engineered Implant Materials with Lactate Dehydrogenase-Like Activity for Sustainable Bone Repair and Regeneration 1.00
A DNA Origami-Based Uricase Nanovehicle for Reducing Blood Uric Acid Levels 1.00
Nanopore Fingerprinting of Structurally Diverse Amino Acid-Conjugated Bile Acids 1.00
Natural Ginger-Derived Exosomes as Effective Therapeutics for Glioblastoma 0.93
Fluorinated Covalent Organic Framework Films Modified Graphene Field-Effect Transistor Biosensors with Size-Dependent Sieving and Antibiofouling Effect 1.00
Nebulized Lipid Nanoparticles Deliver mRNA to the Liver for Treatment of Metabolic Diseases 1.00
Laser–Ultrasound Responsive Nanoreactor to Remodel the Microenvironment of Antibiotic-Resistant Bacterial Infection for Diabetic Wound Healing 1.00
Spatiotemporal Characteristics of the Hierarchical Relaxation Dynamics for Topological Soft Nanoparticles 1.00
Target-Mediated EV-SNA Clustering as an Amplifier for In Situ miRNA Imaging in Living Cells 0.67
Crystal-Phase Engineering Enables Al3+ Liberation from Nanoclay for Ion Interference Tumor Therapy 1.00
An Ultrasensitive Wearable Nanosensor for Minimally Invasive Self-Screening of Alzheimer’s Disease 1.00
Nanopore-Based Electroporation Enables High-Efficiency, Rapid RNA-Mediated Reprogramming of Primary Fibroblasts into Human iPSCs 1.00
Engineering DNA Condensate Droplets as a Versatile Nanovector 1.00
Circularization of Aptamer Nanomedicine Improves Nuclease Resistance, Targeted Recognition, and Transdermal Effect for Topical Psoriasis Therapy 1.00
Imaging Low-Abundance, Short Cellular RNAs Using G-quadruplex FISH 1.00
3 1.97
Multicentre gene therapy for -related deafness followed up to 2.5 years 0.98
Rete ridges form via evolutionarily distinct mechanisms in mammalian skin 0.07
Modelling late gastrulation in stem cell-derived monkey embryo models 0.93
1 1.00
Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells 1.00
4 3.25
A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures 0.25
A continuous totipotent-like cell-based embryo model recapitulates mouse embryogenesis from zygotic genome activation to gastrulation 1.00
Remodelling bivalent chromatin is essential for mouse peri-implantation embryogenesis 1.00
Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm state 1.00
112 101.76
Circulating extracellular microRNAs as tissue-specific biomarkers of human health and disease 0.35
Epitranscriptomic regulation of mRNA stability in pivotal transcription factors modulates the second cell fate decision 1.00
CAR-CD34 (+) hematopoietic stem/progenitor cells produced in vivo protect against thoracic aortic aneurysm and dissection 1.00
Mitophagy promotes lung repair and regeneration by restoring epithelial metabolic fitness 0.92
BRD4 directs myofiber identity and metabolic adaptation through CHD4 cooperation 0.95
Gmppb-mutant mice exhibit dystroglycanopathy symptoms that are rescued with GSK3β inhibition or AAV-mediated GMPPB gene replacement 1.00
De novo-designed ribozyme-controlled riboregulator for cell-free diagnostics 1.00
Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs 0.07
Modulating nuclear stiffness and envelope barrier facilitates AAV nuclear entry and reduces immunogenicity 1.00
Reinforced biotubes as readily available and regenerative vascular grafts 0.96
Aptamers with magnetically tunable affinity for divalent cobalt ions 0.71
Low-intensity focused ultrasound-activated piezoelectric gel bandage for diabetic wound repair and neuropathic pain relief 1.00
A selective enrichment and specific probe terminal mediated strategy for highly sensitive detection of microRNAs 1.00
Endogenous VEGF signaling acts as a guardian of human primed pluripotency 1.00
PTBP1 inhibition reprograms myogenesis to rescue impaired muscle regeneration in mdx mice through correcting E2A splicing 1.00
Perivascular mesenchymal cells instruct ST2+ reparative macrophages to promote endovascular injury-induced neointimal hyperplasia in mice 1.00
Cryo-ET comparison of the hierarchical ultrastructure of silkworm, spider, and artificial silk fibers 1.00
Reversible surface modifications of functional proteins for accelerated cytosolic delivery via cell-penetrating peptide clusters 1.00
Hybrid macrophage-mitochondria extracellular vesicles for mitochondrial ROS regulation in diabetic wounds 0.85
An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice 1.00
Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia 1.00
Sono-mechanical nanostructures-enabled sustained precise ultrasound brain stimulation 1.00
Structural organization of HBV pgRNA genome driven by phase separation in capsid confinement 1.00
Do-it-yourself protein arrays as high-throughput immunoassays enabled by confined droplets on patterned plasmonic chips 1.00
Spatiotemporal interplay between epithelial and mesenchymal cells drives human dentinogenesis 1.00
FOXF2 regulates pericyte–endothelial signaling required for vascular homeostasis after neonatal hyperoxic lung injury 0.45
PRICE: direct and robust detection of microRNAs at single-nucleotide resolution 0.88
Paper-based fluorescent assay for blood typing and antibody titer determination using long-term ambient-stored bioengineered RBCs 1.00
Template-in-template assembly nanostructured microspheres for high performance chromatography 1.00
Bio-orthogonal functionalization of bacterial cellulose combining metabolic glycoengineering and click chemistry 1.00
Organic di-selenide hydrogel microspheres for multimodal treatment of osteoarthritis 1.00
Engineered internal architecture of core-shell lipid nanoparticles promotes efficient mRNA endosomal release 1.00
Engineered VPg saRNA achieves cap-independent, low-immunogenic and precise encoding of therapeutic proteins in vivo 0.79
Homotypic membrane-powered electrochemical microfluidic analysis of extracellular vesicles for precise cancer diagnosis 1.00
Decidualization-empowered ECM hydrogel integrating sustained Tβ4 release drives endometrial regeneration in intrauterine adhesions 1.00
Ependymoglial cells are critical for cortex regeneration in axolotls 1.00
Bionic Janus hydrogel drives infected Achilles tendon regeneration via mechano-immune spatiotemporal steering 1.00
OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states 1.00
Molecular heterogeneity of the non-human primate cochlea 1.00
Wearable textile-based phototherapy platform with customized NIR OLEDs toward non-invasive hair loss treatment 0.25
Filament assembly induced by the recognition of target DNA activates the prokaryotic Argonaute SPARDA system 1.00
Rapid endothelialization of printed vascular grafts by perivascular niche-circulating endothelial progenitors crosstalk 1.00
FGF7 promotes load-bearing tendon regeneration and suppresses fibrosis 1.00
Lymphatic–stem cell crosstalk promotes tendon regeneration via Notch1–Srebp2–mediated cholesterol metabolism 0.89
Pre- and postsynaptic upregulation of FasII synergistically underlies neuropathological and behavioral phenotypes in a Drosophila model of myotonic dystrophy 0.35
S100B triggers neuroendocrine macrophage networks to drive airway regeneration in mice 1.00
AAV-delivered engineered suppressor tRNA rescues visual function in mice with an inherited retinal disease 1.00
Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy 0.50
Transcytotic transportation of size-controlled nanocarriers into dystrophic skeletal muscle leads to therapeutic outcome in mice 0.65
mRNA vaccine developed for sequential selective organ-to-cell targeting of glioma 1.00
Dynamic magnetic fields transform pivoting H2SiO3 particles to hollow microspheres with nanofibrous interior 1.00
Nociceptive sensory neuron-derived NGF orchestrates a fibrotic mesenchymal stromal cell neurogenic niche to drive tendon pathological fibrosis 1.00
Breaking the durability barrier with d band optimized Cu Fe twin crystal nanozymes for long term suppression of Botrytis cinerea 1.00
Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis 0.90
Mitochondria-targeted gene delivery using fluorinated lipid nanoparticles to alleviate Leber’s hereditary optic neuropathy 0.98
An RNA interference therapeutic potentially achieves functional cure of chronic hepatitis B virus infection 1.00
Controlled microphase separation and strain programming in hydrogel fibers toward biomimetic architectures and properties 0.78
Single-cell multiomics analysis reveals CTCF as a key regulator of lung morphogenesis and progenitor maintenance 1.00
Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process 1.00
Directed rescue strategy for enhanced implant osteointegration in aged rats 0.92
Thermally programmed one-pot CRISPR assay for on-site pandemic surveillance 0.78
Microenvironment-responsive multifunctional enzyme-linked hydrogel for diabetic bone defect regeneration 1.00
A newly evolved small secretory peptide enhances mechanical properties of spider silk 1.00
Transcription factor ZNF263 primes human embryonic stem cells for pluripotency dissolution and lineage commitment 1.00
Coupling of polymerase-nucleoprotein-RNA in an influenza virus mini ribonucleoprotein complex 0.78
Interplay of ECM organization, ROCK signaling, and cell polarity drives mesothelium formation and lung growth 0.92
Common genetic variation influencing the human lung imaging phenotypes 1.00
Injectable micropore-forming microgel scaffold for neural progenitor cells transplantation and vascularization after stroke 1.00
Advancing sleep health equity through deep learning on large-scale nocturnal respiratory signals 1.00
Tetrahedral DNA dendritic nanostructure-enhanced FISH for high-speed, sensitive spatial transcriptomics 1.00
Engineering a streamlined virus-like particle for programmable tissue-specific gene delivery 1.00
Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration 1.00
Muscle-specific gene editing therapy via mammalian fusogen-directed virus-like particles 1.00
Programmable afterglow tuning in monodisperse SiO2 microparticles through spatially confined emitter doping 1.00
Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy 1.00
A combined pseudouridine biomanufacturing platform enabled by a streamlined designer pathway 1.00
Stage-specific and cell-autonomous functions of Delta-like 1 in skeletal muscle stem cells and myogenesis 0.06
Metal-organic polyhedra maintain the self-renewal of embryonic stem cells 1.00
Pulsed electromagnetic fields mediate sensory nerve regulation for bone formation in aging models 1.00
Ocular delivery of lipid nanoparticles-formulated mRNA encoding lanosterol synthase ameliorates cataract in rats 1.00
Circular RNA-based protein replacement therapy mitigates osteoarthritis in male mice 1.00
Sensitive pathogen DNA detection by a multi-guide RNA Cas12a assay favoring trans- versus cis-cleavage 0.79
The Notch ligand Jagged1 plays a dual role in cochlear hair cell regeneration 0.42
Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons 1.00
RKIP regulates bone marrow macrophage differentiation to mediate osteoclastogenesis and H-type vessel formation 1.00
Space-confined synthesis of sinter-resistant high-entropy nanoparticle library 1.00
Galectin-3-integrin α5β1 phase separation disrupted by advanced glycation end-products impairs diabetic wound healing in rodents 0.91
Gut microbiota mitigate the reproductive toxicity of silver nanoparticles through thiamine-derived metabolites 1.00
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring 1.00
Stem cell secretome armed magneto-actuated micromotors as spatio-temporal manipulators for wound healing acceleration 1.00
Linear and non-linear proteome-wide association studies provide novel insight into venous thromboembolism 1.00
Increased and synergistic RNAi delivery using MOF polydopamine nanoparticles for biopesticide applications 1.00
Divide-and-conquer strategy with engineered ossification center organoids for rapid bone healing through developmental cell recruitment 1.00
Sono-activable and biocatalytic 3D-printed scaffolds for intelligently sequential therapies in osteosarcoma eradication and defect regeneration 0.97
Bioengineered nanovesicles for efficient siRNA delivery through ligand-receptor-mediated and enzyme-controlled membrane fusion 1.00
Self-reinforced piezoelectric chip for scaffold-free repair of critical-sized bone defects 1.00
Cascade-heterogated proton nanotransistors for multiplex pH-interval imaging 1.00
Rewiring of 3D chromatin topology orchestrates transcriptional reprogramming in muscle fiber-type specification and transformation 1.00
Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles 1.00
Production of live monkeys and their genetically matched embryonic stem cells from single embryos 1.00
In vitro generation of a ureteral organoid from pluripotent stem cells 0.17
Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish 0.04
Forebrain neural progenitors effectively integrate into host brain circuits and improve neural function after ischemic stroke 0.95
De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS 1.00
Deciphering signaling mechanisms and developmental dynamics in extraembryonic mesoderm specification from hESCs 1.00
Freezing induced incorporation of betaine in lipid nanoparticles enhances mRNA delivery 1.00
DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases 0.95
Streamlined metal-based hydrogel facilitates stem cell differentiation, extracellular matrix homeostasis and cartilage repair in male rats 0.89
Immunomodulatory multifunctional janus collagen-based membrane for advanced bone regeneration 1.00
Gene Therapy with Enterovirus 3 C Protease: A Promising Strategy for Various Solid Tumors 1.00
Structure-guided design of endosomolytic chloroquine-like lipid nanoparticles for mRNA delivery and genome editing 1.00
A potent protective bispecific nanobody targeting Herpes simplex virus gD reveals vulnerable epitope for neutralizing 1.00
1 1.00
Maternal factor OTX2 regulates human embryonic genome activation and early development 1.00
6 4.79
Crosslinked ionizable lipids reprogram dendritic cell metabolism for potent mRNA vaccination 0.07
Monolithic cell-on-memristor architecture enables wafer-scale integration of oscillatory chemoreceptors for bio-realistic gustatory chips 1.00
Tissue-specific mRNA delivery and prime editing with peptide–ionizable lipid nanoparticles 1.00
Peptide codes for organ-selective mRNA delivery 0.93
Albumin-recruiting lipid nanoparticle potentiates the safety and efficacy of mRNA vaccines by avoiding liver accumulation 0.78
Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury 1.00
4 1.93
Predicting onset of symptomatic Alzheimerʼs disease with plasma p-tau217 clocks 0.01
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology 0.01
Factor IX-Padua AAV gene therapy in hemophilia B: phases 1/2 and 3 trials 1.00
AAV gene therapy for autosomal recessive deafness 9: a single-arm trial 0.92
3 0.54
Rational design of rigid mRNA folding architecture to enhance intracellular processing and protein production 0.36
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape 0.03
Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches 0.15
1 1.00
piRNA gene density and SUMOylation organize piRNA transcriptional condensate formation 1.00
3 3.00
<atl>Molecular Targeted Suppression of Male Fertility in scp iAmaranthus palmeri/i /scp S. Watson: Function and Layered Double Hydroxide Nanosheets‐Based Delivery System of scpApmiR319/scp</atl> 1.00
An Ultra-Sensitive Quarantine Pathogen On-Site Detection Based on a One-Pot Asymmetric Recombinase Polymerase Amplification and MNAzyme-Assisted Target Recycling Biosensor (OAR-MNA) 1.00
High-Efficiency and Eco-Friendly Management of Multiple Fungal Diseases by a Novel Carbon Dots sCDP Delivered RNA Nano-Pesticides 1.00
25 19.54
Self-adjuvanting α-helical polypeptide simultaneously delivers neoantigen mRNAs and activates dendritic cells to eradicate tumors 0.05
Alternative splicing of the Rbm24 gene is essential for cochlear hair cell stereocilia integrity and hearing function in mice 0.67
Maternal IntS11 primes embryonic totipotency by organizing early zygotic transcription initiation 1.00
Convergence of external and internal stressors on a stress-responsive enhancer of the Sonic hedgehog gene to induce hair disorders 0.89
Endogenous ATP–powered nanomotors directing neural stem cell differentiation for Parkinson’s disease treatment 1.00
m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses 1.00
Charge-reversal proteolysis polymers enable tissue-specific STING degradation in rheumatoid arthritis 1.00
Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification 0.94
Artificially constructed collagen-targeting receptors on mesenchymal stromal cells promote anoikis resistance and tissue repair 1.00
Gpr171 regulates embryonic hematopoietic stem cell emergence via ERK1/2 and Notch signaling 1.00
Adult neural stem cells mediate hippocampal synapse elimination for circuit homeostasis through MERTK 1.00
Fluorinated lipid nanoparticles enable real-time tracking of mRNA delivery and uncover spatiotemporal mechanisms of immune activation 0.92
Dysregulated NAMPT signaling underlines the immune-suppressive microenvironment in venous leg ulcers 0.89
Cryo-EM structure of the Rift Valley fever virus envelope protein in complex with a potent neutralization antibody 1.00
Ace2 safeguards embryonic hematopoietic stem and progenitor cell production by restraining Nlrp3-mediated pyroptosis 1.00
Multipotent progenitors with distinct origins, clonal lineage fates, transcriptomes, and surface markers yield two hematopoietic trees 0.09
An adipo-osteoprogenitor population in the endosteal niche contributes to bone and fat formation in adult mouse bone marrow 0.06
Intrinsically disordered linkers and terminal domains codrive aciniform spidroin self-assembly through liquid–liquid phase separation 0.90
The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development 0.08
Pdgf mediates a transient regeneration-activated cell state in planarian tissue regeneration 1.00
Organoid-based neutralization assays reveal a distinctive profile of SARS-CoV-2 antibodies and recapitulate the real-world efficacy 0.96
Precise antibody delivery to the brain via nanobubble-actuated focused ultrasound alleviates depression 1.00
Structural basis and affinity improvement for an ATP-binding DNA aptamer 1.00
SETDB1 ensures the continuity of embryonic to adult neural stem cells through metabolic alterations in the dentate gyrus 1.00
SHANK2 establishes auditory hair bundle architecture essential for mammalian hearing 0.08
1 1.00
CRISPR/Cas9-Engineered Triple-Fusion Reporter Gene Imaging System for Monitoring Transplanted Neural Progenitor Cells in Ischemic Stroke. 1.00
4 3.69
Commensal-driven serotonin production modulates in vivo delivery of synthetic and viral vectors 1.00
SPARK-seq: A high-throughput platform for aptamer discovery and kinetic profiling 1.00
Deep generative models design mRNA sequences with enhanced translational capacity and stability 0.69
Reactivation of mammalian regeneration by turning on an evolutionarily disabled genetic switch 1.00
33 28.24
Targeted intracellular oral RNA delivery through tea polyphenol nanovesicle to outer membrane vesicle transfer for colitis treatment 1.00
One-component ionizable amphiphilic Janus dendrimers as a delivery platform for efficient mRNA vaccine development 0.19
A worm-like nucleic acid nanostructure for gene delivery and endosomal escape via ClC3 ion exchanger 1.00
Activation of the YAP1/pSTAT3/NRP1 axis in peritendinous sensory nerves promotes tendon healing 1.00
Cell surface engineering with a pseudofibrotic ECM reprograms the antifibrotic activity of mesenchymal stromal cells 1.00
Control of airway basal stem cell–mediated lung repair by TGF-β signaling 1.00
Facile active gel–enhanced synthesis of molecular-sieving membranes with record-breaking performance 0.83
Spectral fingerprint diagnosis: Spatially independent analysis of biomarker patterns in homogeneous systems 1.00
Ultrasonic cavitation shock wave exfoliation dynamics of 2D materials revealed in situ by MHz XFEL imaging and multiphysics modeling 0.02
Structure-guided design of nucleosome-inspired nanoparticles for overcoming pulmonary barriers in fibrotic lung gene therapy 1.00
Blocking nuclear receptor Nr4a3 unlocks the senescence barrier to promote direct cardiac reprogramming 1.00
Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation 0.03
Xenopus IgX informs engineering strategies of IgM and IgG hexamers 1.00
Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging 0.10
Cascade-targeting pH/ROS microneedles promote scarless diabetic wound healing by macrophage metaboimmune reprogramming 1.00
Ionizable guanidine-based lipid nanoparticle for targeted mRNA delivery and cancer immunotherapy 1.00
Spatiotemporally controlled delivery of biological effectors from nanofiber scaffolds accelerates skin wound healing in porcine models 0.89
Reinforced plant-derived lipid nanoparticles for oral precise epigenome editing in colonic diseases 0.81
Integrated horizontal convective PCR system for clinical diagnostics 1.00
An energy-embodied paralleled liquid manipulation for equipment-free, quantitative multiplexed liver function monitoring 1.00
A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy 1.00
Neurons derived from NeuroD1-expressing astrocytes transition through transit-amplifying intermediates but lack functional maturity 0.67
Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3 0.89
Architecture mechanics mediated osteogenic progression in bone regeneration of artificial scaffolds 1.00
A wearable device for continuous immunoassay-based monitoring of C-peptide in interstitial fluid 1.00
Dynamically covalent lipid nanoparticles mediate CRISPR-Cas9 genome editing against choroidal neovascularization in mice 1.00
Pressure-driven microinjection (PMI) of porous-coated balloon for ultrafast endoluminal drug delivery across biological barriers 1.00
Widespread presence of bone marrow–like hematopoietic stem cell niche in invertebrate skeletons 1.00
A spatially organized Cd24a+/Pax9+ stem cell core governs postnatal tooth establishment 1.00
Mechanoregulative hydrogel facilitates rapid scarless healing by self-adaptive control of wound niche at different stages 1.00
PTMA controls cardiomyocyte proliferation and cardiac repair by enhancing STAT3 acetylation 1.00
Hedgehog-interacting protein orchestrates alveologenesis and protects against bronchopulmonary dysplasia and emphysema 0.82
A tube-based biosensor for DNA and RNA detection 1.00
4 3.51
Aberrant bone marrow granulopoiesis generates neutrophils that promote B cell activity in neuromyelitis optica spectrum disorder 0.94
HDAC5 deacetylates cytosolic ACTN4 during skin reepithelialization and represents a therapeutic target for chronic wound healing 1.00
A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical models 0.97
A complete Sigmodon hispidus genome and dynamic single-cell transcriptomics reveal evolutionarily conserved responses to RSV infection 0.61
3 1.08
TET knockout cells transit between pluripotent states and exhibit precocious germline entry. 0.04
NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction. 0.04
GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1+ tendon sheath progenitors 1.00
2 2.00
Structural Passivation Engineering of Montmorillonite Nanoclay Attenuates the ROS–HIF-1α–Ferroptosis Axis for Enhanced Biosafety 1.00
Release-Independent Transcription from Covalently Cross-Linked Hierarchically Folded DNA Condensates 1.00
1 0.08
Efficacy and safety of inclisiran in adolescents with heterozygous familial hypercholesterolaemia (ORION-16): a two-part, randomised, multicentre clinical trial 0.08
1 0.01
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis 0.01
1 0.07
Mim8 Bispecific Antibody Prophylaxis in Hemophilia A with or without Inhibitors 0.07
2 2.00
Analysis of the removal process of residual tetrachloroethylene from simulated aquifer by a novel anionic-nonionic gemini surfactant 1.00
Click Chemistry-Empowered Multi-Channel Biosensing for Highly-Efficient Detection of Antibiotic Resistance Genes in Aquatic Environments 1.00

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