Medical Biotechnology articles for United Kingdom (UK)

Time frame: 1 June 2025 - 30 May 2026

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Count: 141

Article ‘Count’ for Medical Biotechnology.

Journal Count Share
5 1.72
Caveolar Endocytosis Governs Nanoneedle Transfection 0.75
Polyanion Chemistry Engineers Ternary RNA Nanoparticle Structure/Function from the Inside-Out 0.71
Osteoinductive and Piezoelectrically Malleable Nanocomposite Bone Graft 0.07
Direct Reversible Conjugation of an Adenosine Receptor Antagonist to an Axonal Transport Protein Carrier 0.10
Mechanically Matched Heart-on-a-Chip Platform Mediated Maturation of Excitation–Contraction Coupling 0.08
2 0.79
Improved in vivo bone regeneration and mechanical stability in critical-sized defects using WZM211 fluorine coated fibres 0.71
Inflammation-Responsive Biodegradable Nanocomposite Hydrogels for Enhanced Metalloimmunotherapy in Chronic Periodontitis 0.07
7 1.36
SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement 0.07
PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing 0.25
Revealing the Auxetic Behavior of Biomimetic Multimaterial and Region-Specific Nanofibrous Fascicle-Inspired Scaffolds via Synchrotron Multiscale Digital Volume Correlation: Innovative Building Blocks for the Enthesis Regeneration 0.13
A Peptide Nucleic Acid‐Functionalized Heterojunction Thin Film Transistor as a Scalable and Reusable Platform for Label‐Free Detection of MicroRNA 0.17
From Snapshot to Movie: Visualizing Native Silk Spinning Defines the Paradigm for Bio‐Inspired Spinning 0.14
Metal‐Organic Nanosheet Gels: Hierarchically Porous Materials for Selective Loading and Differential Release 0.50
Biomimetic Bacterial Framework‐Driven Point‐of‐Care Platform Enables Broad‐Spectrum Bacterial Sensing via PAMPs‐Triggered Competitive Recognition 0.10
3 1.10
Modular Supramolecular Polycations Enable Efficient Delivery of Diverse RNA Therapeutics and Vaccines 0.96
Microbubble Shell Stiffness Engineering Enhances Ultrasound Imaging, Drug Delivery, and Sonoporation 0.06
Dual‐Selective Terahertz‐Nanodisc Metasurfaces for Exploring Neurotransmitter Dynamics beyond Spectral Limitations 0.07
1 0.05
Enhanced muscle uptake of chemically optimized miR-23b antisense oligonucleotides as lead compounds for myotonic dystrophy type 1 0.05
6 3.57
DYNAMIC: A Novel Software Implementation of a Kinetic Model of TaqMan PCR 0.64
Programmable Hairpin Argonaute–Nanopore Detection System for Multiplex Mycotoxin Analysis 0.14
Infrared Spectroscopic Profiling of Volatile Metabolites from Uropathogenic Bacteria: Basic Investigations toward Rapid UTI Diagnostics 0.08
Application of Rapid Evaporative Ionization Mass Spectrometry (REIMS) to Identify Antimicrobial Resistance in Uropathogenic iEscherichia coli/i (UPEC) Isolates via Deuterium Isotope Probing 1.00
Smart-Plexer 2.0: Leveraging New Features of Amplification Curves to Enhance the Selection of Multiplex PCR Assays in Multi-Target Identification 1.00
Microarray-Based Nanoextraction Combined with Ambient Ionization Mass Spectrometry for Analysis of Drugs of Abuse in Wastewater 0.70
3 1.98
Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA‐Charge Neutral Linkages for Enhanced Splice‐Switching Antisense Oligonucleotides 0.96
Logic-Gated Release of a Dual Payload from a β-Lactam Mechanophore with a Rotaxane Actuator 1.00
AM-DMF-ddRPA: an All-in-One Digital Microfluidic Platform for Rapid and Automatic Digital Nucleic Acid Analysis 0.02
1 0.01
Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau scpPET/scp Clocks 0.01
2 1.13
Effect of intra-articular adipose-derived mesenchymal stromal cell versus placebo injection on pain and function in patients with knee osteoarthritis: the ADIPOA2 phase 2b randomised clinical trial 0.13
Spatial transcriptomic analysis of muscle biopsy from patients with treatment-naive juvenile dermatomyositis reveals mitochondrial abnormalities despite disease-related interferon-driven signature 1.00
1 0.09
Performance enhancement of Love wave sensor via a cost-effective and robust dual-layered waveguide 0.09
4 0.90
Von Willebrand factor deficiency impairs angiogenesis via angiopoietin-2: relevance for gut angiodysplasia 0.78
The interleukin-33 receptor (ST2) is a novel therapeutic target to attenuate the progression of hemophilic arthropathy 0.05
Tracking iclusterin/i expression in hematopoietic stem cells reveals their heterogeneous composition across the life span 0.05
Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study 0.03
7 1.88
Combined magnetic resonance imaging and serum analysis reveals distinct multiple sclerosis types 0.53
Muscle transcriptomics of alpha-sarcoglycanopathy highlights inflammatory pathways driving disease 0.04
Plasma phosphorylated tau217 strongly associates with memory deficits in the Alzheimer’s disease spectrum 0.01
Remyelination of chronic demyelinated lesions with directly induced neural stem cells 0.70
Exon skipping peptide-conjugated morpholinos downregulate dynamin 2 to rescue centronuclear myopathy 0.38
Deciphering iDST/i-associated disorders: biallelic variants affecting DST-b cause a congenital myopathy 0.14
Disease spectrum and long-term prognosis of patients with iBAG3/i-associated neuromuscular diseases in Europe 0.09
2 0.32
Fertilization triggers early proteomic symmetry breaking in mammalian embryos 0.27
A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells 0.04
3 2.12
Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology and cognitive resilience 0.12
comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders 1.00
Hypoxia promotes airway differentiation in the human lung epithelium 1.00
2 2.00
Differential self-assembly of sequence-isomeric phosphoestamers 1.00
Maximising the translation potential of electrochemical biosensors 1.00
4 2.46
A platform to design and optimise fluorogenic scFvs for detection of interleukin 33 0.57
A robust Au–C≡C anchoring group greatly improves the signal stability of electrochemical aptamer-based sensors for in vivo measurements 0.29
Degradable polyphosphoester-based aqueous two-phase systems and water-in-water emulsions 0.60
Engineering antisense oligonucleotides for targeted mRNA degradation through lysosomal trafficking 1.00
1 0.11
Songbird connectome reveals tunneling of migratory neurons in the adult striatum 0.11
3 2.05
Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation 1.00
Efficient stem cell-derived mouse embryo models for environmental studies 0.05
Eomes directs the formation of spatially and functionally diverse extraembryonic hematovascular tissues 1.00
1 0.10
Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials 0.10
1 0.07
Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation 0.07
1 0.23
TFIIH-p52∆C defines a ninth xeroderma pigmentosum complementation-group XP-J and restores TFIIH stability to p8-defective trichothiodystrophy 0.23
1 0.13
Canine Olfaction Combined With Bayesian Modeling for Multicancer Detection From Breath Samples: A Phase II Study in India. 0.13
1 0.68
Transcriptomic and epigenetic mechanisms controlling cholangiocytes transdifferentiation into hepatocytes 0.68
2 1.45
Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects 0.60
Adeno-associated virus-based rescue of Myo7a expression restores hair-cell function and improves hearing thresholds in a USH1B mouse strain 0.85
4 3.00
Structural Analysis of Valine Residues in Silk Fibroin by Solid-State NMR 0.20
Kinetic Locking of pH-Sensitive Complexes for Mechanically Responsive Polymer Networks 1.00
Harnessing BET-Bromodomain Assisted Nuclear Import for Targeted Subcellular Localization and Enhanced Efficacy of Antisense Oligonucleotides 1.00
Degradable Diblock Copolymer Vesicles via Radical Ring-Opening Polymerization-Induced Self-Assembly in Aqueous Media 0.80
1 0.26
Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6 0.26
1 0.01
A kinetics-based model of haematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells 0.01
29 11.68
ANXA11 suppression restores muscular function in the mdx mouse model of Duchenne muscular dystrophy (DMD) 0.04
Alzheimer’s Disease blood biomarkers measured through remote capillary sampling correlate with cognition in older adults 0.44
NELFA supports naïve pluripotency and drives 8C-like state in human embryonic stem cells 0.27
Lifetime chemical sensor arrays of organic fluorophores for bacterial fingerprinting 1.00
GWAS meta-analysis of cerebrospinal fluid Alzheimer’s biomarkers reveals loci regulating lipids, brain volume and autophagy 0.06
Developmental system drift in dorsoventral patterning is linked to transitions to autonomous development in Annelida 0.55
Restorative macrophage-derived RNAseT2 stimulates muscle stem cell fusion via an SLK/N-WASP/actin bundling dependent axis 0.11
Ultrahigh strength magnesium via solidification of nanocolloid 0.58
PRICE: direct and robust detection of microRNAs at single-nucleotide resolution 0.04
In vivo CRISPR screening identifies SAGA complex members as key regulators of hematopoiesis 0.33
Uncertainty-aware machine learning to predict non-cancer human toxicity for the global chemicals market 0.33
A binary self-amplifying expression platform enabling lipid nanoparticle-free vaccines and nanomedicines 0.07
Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy 0.50
Revealing heterogeneity and damage response in the adult human utricle 0.11
Early skin seeding regulatory T cells modulate PPARγ-dependent skin pigmentation 0.92
The nucleobase guanine at the 3’-terminus of oligonucleotide RGLS4326 drives off-target AMPAR inhibition and CNS toxicity 0.09
Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity 0.91
Mapping cell dynamics in human ex vivo hair follicles suggests pulling mechanism of hair growth 0.13
Spatial single-cell atlas reveals regional variations in healthy and diseased human lung 0.07
Coupling of polymerase-nucleoprotein-RNA in an influenza virus mini ribonucleoprotein complex 0.17
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics 0.08
Targeted high-resolution sensing of volatile organic compounds by covalent nanopore detection 1.00
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 0.78
Multiplex bead assays enable integrated serological surveillance and reveal cross-pathogen vulnerabilities in Zambezia Province, Mozambique 0.16
Temporo-spatial cellular atlas of the regenerating alveolar niche in idiopathic pulmonary fibrosis 0.94
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst 0.80
Raised Leptin and Pappalysin2 cell-free RNAs are the hallmarks of pregnancies complicated by preeclampsia with fetal growth restriction 0.45
Immunocompetent cell targeting by food-additive titanium dioxide 0.73
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC 0.01
1 0.06
Stable clonal contribution of lineage-restricted stem cells to human hematopoiesis 0.06
5 1.35
Predicting onset of symptomatic Alzheimerʼs disease with plasma p-tau217 clocks 0.01
Contaminating plasmid sequences and disrupted vector genomes in the liver following adeno-associated virus gene therapy 1.00
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology 0.11
Cardiotropic AAV gene therapy for heart failure: a phase 1 trial 0.02
Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions 0.20
2 0.83
Compact polyethylenimine-complexed mRNA vaccines 0.08
Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches 0.75
1 0.42
Hierarchical materials from fused silk 0.42
1 1.00
New Approach to Assembling Nucleic Acid Dendrons on a Solid Phase 1.00
1 0.14
Multispecies characterization of immature neurons in the mammalian amygdala reveals their expansion in primates 0.14
1 0.92
Nicotiana benthamiana as a Source of Cowpea Mosaic Virus-Derived Particles That Specifically Package Designer RNAs 0.92
5 2.13
Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly 0.25
Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification 0.03
Unraveling the maturation pathway of a eukaryotic virus through cryo-EM 0.71
VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment 0.14
MC1R determines healing outcomes in acute and chronic cutaneous wounds 1.00
3 0.98
Hyaluronic acid and tissue mechanics orchestrate mammalian digit tip regeneration 0.82
Single intramuscular injection of self-amplifying RNA of Nppa to treat myocardial infarction 0.09
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation 0.07
7 2.22
Immunometabolic resistors of aging in long-lived golden spiny mice 0.08
Role of CEBPa in trophectoderm competence installment 0.12
Ultrasonic cavitation shock wave exfoliation dynamics of 2D materials revealed in situ by MHz XFEL imaging and multiphysics modeling 0.32
Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation 0.11
Size matters: Micro- versus nanobubbles in ultrasound imaging and therapy 1.00
Enhanced immunocompatibility and hemocompatibility of nanomedicines across multiple species using complement pathway inhibitors 0.10
Sequential transcriptional programs underpin activation of hippocampal stem cells 0.50
2 0.21
HIF1α gates tendon response to overload and drives tendinopathy independently of vascular recruitment 0.12
Restoration of progranulin by engineered hematopoietic stem cell–derived microglia corrects phenotypes of granulin knockout mice 0.09
4 2.73
Quiescent neural stem cells transiently become neuron-like to coordinate long-range reactivation 0.83
Serum coating enables feeder-free culture of naive human pluripotent stem cells preserving developmental potential 0.02
TET knockout cells transit between pluripotent states and exhibit precocious germline entry. 0.92
NANOG is repurposed after implantation to repress Sox2 and begin pluripotency extinction. 0.96
1 0.06
Physicochemical Properties of a Water-Soluble Adduct of Csub60/sub with scpl/scp-Cysteine for Biomedical Applications 0.06
2 0.07
Overall survival with relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA): a phase 3 randomised controlled trial 0.02
Relacorilant and nab-paclitaxel in patients with platinum-resistant ovarian cancer (ROSELLA): an open-label, randomised, controlled, phase 3 trial 0.05
3 0.23
Safety and efficacy of fordadistrogene movaparvovec in ambulatory participants with Duchenne muscular dystrophy (CIFFREO): a phase 3, double-blind, randomised, placebo-controlled study 0.14
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis 0.04
Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers: a longitudinal cohort study 0.05
3 0.63
Mim8 Bispecific Antibody Prophylaxis in Hemophilia A with or without Inhibitors 0.07
DB-OTO Gene Therapy for Inherited Deafness 0.06
Sustained Clinical Benefit of AAV Gene Therapy in Severe Hemophilia B 0.50

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