Pharmacology and Pharmaceutical Sciences articles for University of Chinese Academy of Sciences (UCAS), China

Time frame: 1 June 2025 - 30 May 2026

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Count: 73

Article ‘Count’ for Pharmacology and Pharmaceutical Sciences.

Journal Count Share
9 1.43
Nose-to-Brain Delivery of mRNA-Loaded Lipid Nanoparticles Bypasses the Blood–Brain Barrier for Effective Brain Disease Therapy 0.27
Reversing Cuproptosis Tolerance with Twinborn Metallic Polymer Nanoparticles for Enhancing Efficacy of Chemo-Immunotherapy 0.50
A Redox-Responsive Selenium-Containing Nanomedicine Enables Dual Antioxidant System Inhibition to Overcome Platinum Resistance and Enhance Immunotherapy in Bladder Cancer 0.06
Chiral Polyproline Enables Functional Stealth for Simultaneous Long Circulation and Endoplasmic Reticulum-Targeted Antigen Presentation 0.02
Structure-to-Therapeutic Transformation of Nanohydrogels Triggers Calcium Overload for Potentiated Boron Neutron Capture Therapy 0.09
In Vivo Programmed Assembly of Polymer–Peptide Conjugates to Overcome Multistage Drug Delivery Barriers 0.29
Holistic and Multivalent Engineering of In Vivo Nanomedicine Reactions for Enhanced Multistage Tumor Delivery 0.07
Nanoparticles Induce Protein Corona Conformational Change to Reshape Intracellular Interactome for Microglial Polarization 0.10
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping 0.04
2 0.36
Biomimetic zwitterionic micelles for efficient mucus penetration and pulmonary targeting in acute lung injury 0.26
Multifunctional pH-responsive nanocarrier for targeted azithromycin delivery and immune modulation in bacterial sepsis 0.10
1 0.33
Terminal Group‐Determined and Dendrimer‐Encapsulated Perovskite Probes for High‐Contrast Biomedical Imaging 0.33
3 0.66
Dynamically Hydrogen-Bonded Microphase Separation Enabling Phase Transition in the Gel Composites With Tunable UCST 0.50
Synthetic High‐Density Lipoprotein Mimicking Nanodiscs with Pt(IV) Prodrug Enable Tumor Targeting and cGAS‐STING Pathway Activation for Chemo‐Immunotherapy 0.08
Lipidic Prodrug Co-Crystals: A Platform for Combination Therapy Targeting Fungal Biofilms 0.07
11 2.51
A Scalable, Direct-to-Biology Platform for Accelerated Discovery of Cereblon-Based Molecular Glue Degraders 0.20
Amphiphilic Zwitterionic Polymers Induce Liposome Morphogenesis into Nanodiscs for Deep Glioblastoma Infiltration 0.04
Benzaldehyde‐Tagged Cell‐Penetrating Peptides Enable Efficient Cytosolic Delivery of Bioactive Cargos via Dynamic Covalent Anchoring 0.38
Counterion-Engineered Water-Stable Intravenously Administered Nanoparticles Enable In Vivo Reversal of Ticagrelor 0.29
Kinetically Stereocontrolled Gem-Fluoro(chloro)-Olefination of Carbonyls by an Unprecedented Sulfoximine: Programmable Construction of Challenging Persubstituted Alkenyl Fluorides 0.05
Ionizable Nano-PROTAC Overcomes Endosomal Entrapment for Enhanced LRG1 Degradation and Tumor Suppression 0.09
De Novo Design of Hexamer‐Linker Dual‐Action Nano‐PROTAC for Tumor‐Specific Ferroptosis 0.15
A Self‐Homing Liposomal Nanobot for Active Therapy of Glioblastoma 0.50
Visible‐Light‐Mediated Intramolecular Dearomatization of Naphthalene and Anthracene with Bicyclo[1.1.0]butanes Through Energy Transfer Catalysis 0.33
Stereoselective Nucleophilic Di‐ and Monofluoro(sulfoximidoyl)Methylation of C═C Bonds: Remote Neighboring Group Participation Enables Facile Access to Chiral γ‐Fluorinated Amines 0.31
De Novo Design of Structure‐Tunable Multivalent Targeting Chimeras for Tumor‐Targeted PD‐L1 Degradation and Potentiated Cancer Immunotherapy 0.17
1 0.50
Multimodal supramolecular targeting chimeras enable spatiotemporally resolved protein degradation in vivo 0.50
1 0.20
Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates 0.20
1 0.15
Vitamin C conveys geroprotection on primate ovaries 0.15
4 1.54
Facile access to difluoromethylene-linked strained aliphatic rings from 2-(difluoromethylene)cyclobutyl sulfonium salts (CB-DFAS) and [1.1.1]propellane 0.33
J-aggregates of ethene-bridged aza-BODIPY dimers for bright NIR-II bioimaging and efficient photothermal therapy 0.48
Programmable PROTAC delivery for precise and spatiotemporal protein degradation 0.38
A CRISPR Cas protein coronated AuNP nanostructure for enhanced uptake efficiency into cells 0.36
1 0.57
Difluoromethylene cyclobutyl sulfonium salts: versatile reagents for chemodivergent synthesis of difluoroalkylated cyclobutenes and cyclobutanes 0.57
1 0.30
VOCs emission from landfills co-disposed of rural solid waste and sewage sludge: Identification, diffusion, and impact 0.30
4 1.56
Intermolecular Interactions as the Bridge: Establishing Structure–Activity Relationships between Microscopic Features of Organophosphorus Compounds (OPCs) and Their Adsorption Performance 0.29
Dynamic Evolution of Fe3O4 Nanoparticles’ Protein Corona during Extracellular to Intracellular Trafficking: The Interference of Integrin αMβ2 0.58
Arsenic Impairs Crab Carapace Sclerotization after Molting by Interfering with Phosphorus Metabolism 0.19
Single-Nucleus Transcriptomics Reveals Prenatal and Postnatal Pb Exposure-Induced Cell-Specific Neurotoxicity and Dysregulated Microglia-Neuron Communication in Mice Brain 0.50
1 0.31
Selenoprotein P deficiency drives hepatocellular carcinoma progression via induction of neutrophil senescence and immunosuppressive microenvironment 0.31
1 0.28
Multiscale Modeling and Experimental Validation of Solvent-Mediated Crystal Morphology Control in Sr(OH)2·8H2O for Industrial Crystallization Processes 0.28
5 0.65
Micron-Scale 2D Antibody Arrays for HER2 Signaling Blockade and Cancer Therapy 0.02
Iridium-Catalyzed Enantioselective C(sp3)–H Borylation of Bicyclo[1.1.0]butanes 0.13
A Versatile Bioorthogonal Theranostic Platform Enables Relay Activation of Tumor Cell Imaging and Targeted Protein Degradation 0.17
Biocatalytic- and Chemoproteomic-Guided Discovery of a PHGDH Inhibitor from Chemoenzymatic-Promoted DNA-Encoded Libraries Selection Platform 0.21
Enzymatic Basis of Stereochemical Control in Reserpine Biosynthesis 0.13
2 0.62
Role of Poly(ethylene glycol) Di(meth)acrylate Cross-linkers in Modulating Structures of Hexagonal Lyotropic Liquid Crystal toward Enhanced Nanofiltration 0.12
Hydrogen Bonding Mechanism in Cononsolvency 0.50
2 0.13
Synergistic Chemoimmunotherapy of Hepatocellular Carcinoma via ROS-Responsive Carrier-Free Prodrug Nanoparticles 0.03
Hydrophobically Modified Paclitaxel Prodrug Enables Ultrahigh Drug Loading Driven by Polarity Redistribution 0.10
1 0.05
Crystal structures of agonist-bound human cannabinoid receptor CB1 0.05
1 0.18
A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2 0.18
14 1.94
Structural characterization of kappa-opioid receptor dimer in complex with two G proteins 0.02
Rational design of a Kappa opioid receptor peptide agonist with attenuated β-arrestin signaling 0.06
LaMGen: LLM-based 3D molecular generation for multi-target drug design 0.06
Bioengineered ferritin-based lysosome-targeting chimera platform for tumor-targeted therapy 0.04
Engineered exosome nanovesicles for delivery of antibodies to treat inflammatory bowel disease 0.03
Alternative antigen retention by a gp96-fusion approach induces long-lasting and broad immunity in mice 0.30
Structural basis for pharmacotherapeutic action of triple reuptake inhibitors 0.44
Molecular basis of prostaglandin E reuptake by organic anion transporter PGT 0.09
Cryo-EM structure of the full-length LGR4-RSPOs complex and a targeting nanobody for anti-obesity therapy 0.05
Modular synthesis of CF-containing compounds with PhSOCFH reagent through difluoromethylene radical anion synthon strategy 0.45
Targeted degradation of cell surface proteins through endocytosis triggered by cell-penetrating peptide-small molecule conjugates 0.08
Unlocking tumor barrier: annexin A2-mediated transcytosis boosts drug delivery in pancreatic and breast tumors 0.14
Boosting RNA nanotherapeutics with V-ATPase activating non-inflammatory lipid nanoparticles to treat chronic lung injury 0.05
SE(3)-equivariant ternary complex prediction towards target protein degradation 0.13
1 0.29
Difluorocarbene as a Dual C1/CF2 Source for HCF2S Heterocycle Synthesis 0.29
1 0.15
Enhanced screening via a pure DNA-encoded peptide library enabled by an Fmoc modification 0.15
3 0.26
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia 0.03
Site-specific adaptive nanovesicles for oral insulin delivery 0.19
Construction of a whole-brain panorama for glioma vasculature reveals tumor heterogeneity and blood-brain barrier disruption 0.04
1 0.24
Intestinal TGR5-targeted carrier-drug conjugate improves glycemic control in mice and pigs 0.24
1 0.04
Structural insights into selective and dual antagonism of EP2 and EP4 prostaglandin receptors 0.04

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