By silencing intracortical excitation in mouse primary visual cortex, Li and colleagues find that the tuning of layer 4 pyramidal cells is independent of cortico-cortical inputs. Instead, intracortical excitation amplifies thalamocortical signals and expands the spatial receptive field of layer 4 neurons.
- Ya-tang Li
- Leena A Ibrahim
- Huizhong Whit Tao