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Showing 1–50 of 189 results

Advanced filters: Author: Ahmed Mir Clear advanced filters

A high-performance hydrogel platform enabling dual anti-miR-21 and TGF-β1 delivery to improve arterial plaque stability and enhance therapeutic angiogenesis outcomes

Paromita Islam
Ahmed Abosalha
Satya Prakash
ResearchOpen Access23 Jan 2026
Scientific Reports

Volume: 16, P: 1-14
RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer

Treekitkarnmongkol, Katayama, Sankaran et al. identify RASH3D19 as a downstream target for KRAS signalling through miR-301a, which in turn leads to RAS activation and tumorigenesis. Targeting RASH3D19 inhibits growth of KRAS-mutant tumour cells in vivo.

Warapen Treekitkarnmongkol
Hiroshi Katayama
Subrata Sen
Research01 Dec 2025
Nature Cell Biology

Volume: 28, P: 197-206
Rapid reagent free COVID19 detection using MEMS based FTIR spectroscopy and machine learning in NIR and MIR regions

Ahmed Abdelkhalik
Mazen Erfan
Diaa Khalil
ResearchOpen Access07 Oct 2025
Scientific Reports

Volume: 15, P: 1-12
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

Clonal expansion of helper T lymphocytes initially requires inactivation of the transcription factor Foxo1 by post-translational modifications. Mashreghi and colleagues now show in the late phase of clonal expansion, Foxo1 is inhibited post-transcriptionally by the microRNA miR-182.

Anna-Barbara Stittrich
Claudia Haftmann
Mir-Farzin Mashreghi
Research10 Oct 2010
Nature Immunology

Volume: 11, P: 1057-1062
Mechanistic insights into the lipotropic and atheroprotective effects of rosuvastatin-loaded glycerosomes in dyslipidemic rats

Mohamed Fouad Mansour
Rabab A. Husseini
Mahran Mohamed Abd El-Emam
ResearchOpen Access29 Jan 2026
Scientific Reports

P: 1-20
The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

The miR-200 family of miRNAs is upregulated in diabetes and leads to the apoptosis of pancreatic beta cells, while its knockout prevents this pathology

Bengt-Frederik Belgardt
Kashan Ahmed
Markus Stoffel
Research18 May 2015
Nature Medicine

Volume: 21, P: 619-627
Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair

Here, the authors report on the discovery of physiological vasculogenic fibroblasts capable of forming functional blood vessels. In vivo tissue reprogramming triggered by topical tissue nanotransfection (TNT) of a single anti-miR-200b oligonucleotide achieved therapeutic tissue vascularization.

Durba Pal
Subhadip Ghatak
Chandan K. Sen
ResearchOpen Access28 Feb 2023
Nature Communications

Volume: 14, P: 1-20
The diagnostic value of LncRNA NEAT1 targeting miR-129-5p in pancreatic cancer patients

Hadeer Saied Mahmoud
Noha Abdel-Rahman Eldesoky
Ahmed A. El-Husseiny
ResearchOpen Access29 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
Serum expression signature of TUG1, MALAT1, miR-483, and miR-141 and their targets TGF-β1 and STAT3 in severe male factor infertility

Mahmoud A. Senousy
Olfat G. Shaker
Ghada Ayeldeen
ResearchOpen Access27 May 2025
Scientific Reports

Volume: 15, P: 1-18
MyomiR-133 regulates brown fat differentiation through Prdm16

Brown adipose tissue generates heat on exposure to cold temperatures. Stoffel and colleagues identify a cold-regulated pathway that increases levels of the transcriptional regulator Prdm16 to promote brown adipogenesis.

Mirko Trajkovski
Kashan Ahmed
Markus Stoffel
Research11 Nov 2012
Nature Cell Biology

Volume: 14, P: 1330-1335
Role of immune-inflammatory biomarkers and their derived ratio in predicting COVID-19 severity and mortality

Sara I. Taha
Shaimaa H. Fouad
Rasha Ahmed Ghorab
ResearchOpen Access07 Nov 2025
Scientific Reports

Volume: 15, P: 1-10
An unnatural enzyme with endonuclease activity towards small non-coding RNAs

Endonucleases play crucial roles in various biological processes but endonucleases that target small non-coding RNAs have not been reported. Here, the authors combined the metal binding non-canonical amino acid BpyAla and a high affinity binder to engineer a catalyst that degrades small non-coding RNAs.

Noreen Ahmed
Nadine Ahmed
John Paul Pezacki
ResearchOpen Access24 Jun 2023
Nature Communications

Volume: 14, P: 1-12
miRNA biomarkers for prognosis and therapy monitoring in a multi-ethnic cohort with SARS-CoV-2 infection

Farah Mustafa
Waqar Ahmad
Tahir A. Rizvi
ResearchOpen Access21 Aug 2025
Scientific Reports

Volume: 15, P: 1-21
Machine learning-based multimodal biomarkers enable accurate diagnosis and early detection of pancreatic ductal adenocarcinoma

Tsung-Hung Yao
Warapen Treekitkarnmongkol
Suprateek Kundu
ResearchOpen Access07 Jan 2026
Scientific Reports

Volume: 16, P: 1-15
A first-in-class fully modified version of miR-34a with outstanding stability, activity, and anti-tumor efficacy

Ahmed M. Abdelaal
Ikjot S. Sohal
Andrea L. Kasinski
ResearchOpen Access05 Sept 2023
Oncogene

Volume: 42, P: 2985-2999
Lymphocyte to monocyte ratio predicts survival and is epigenetically linked to miR-222-3p and miR-26b-5p in diffuse large B cell lymphoma

Ayman Mohamed Metwally
Ameera Abdel Hamed Mahmoud Kasem
Lobna Ahmed Refaat
ResearchOpen Access25 Mar 2023
Scientific Reports

Volume: 13, P: 1-13
Circulating miR-146b and miR-27b are efficient biomarkers for early diagnosis of Equidae osteoarthritis

Aya M. Yassin
Huda O. AbuBakr
Eman M. Gouda
ResearchOpen Access17 May 2023
Scientific Reports

Volume: 13, P: 1-11
Aberrant expression of miR-133a in endothelial cells inhibits angiogenesis by reducing pro-angiogenic but increasing anti-angiogenic gene expression

Suhail Ahmed
Sathishkumar Kurusamy
Angel L. Armesilla
ResearchOpen Access30 Aug 2022
Scientific Reports

Volume: 12, P: 1-15
MicroRNA-141-regulated KLK10 and TNFSF-15 gene expression in hepatoblastoma cells as a novel mechanism in liver carcinogenesis

Ahmed M. Awad
Emad Dabous
Hany Khalil
ResearchOpen Access12 Jun 2024
Scientific Reports

Volume: 14, P: 1-18
MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance

Faryal Mehwish Awan
Anam Naz
Hussnain Ahmed Janjua
ResearchOpen Access13 Sept 2017
Scientific Reports

Volume: 7, P: 1-21
The role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter

Paradesi Naidu Gollavilli
Beatrice Parma
Paolo Ceppi
ResearchOpen Access02 Mar 2021
Oncogene

Volume: 40, P: 2309-2322
GAS5 rs2067079 and miR-137 rs1625579 functional SNPs and risk of chronic hepatitis B virus infection among Egyptian patients

Rania H. Mahmoud
Enas Mamdouh Hefzy
Omayma O. Abdelaleem
ResearchOpen Access08 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
Nutrient requirements of organ-specific metastasis in breast cancer

How the complex interplay between multiple nutrients within the microenvironment dictates potential sites of metastatic cancer growth is explored.

Keene L. Abbott
Sonu Subudhi
Matthew G. Vander Heiden
ResearchOpen Access07 Jan 2026
Nature

Volume: 649, P: 1292-1301
A microRNA-based dynamic risk score for type 1 diabetes

A 50 microRNA-based dynamic risk score for stratifying individuals with and without type 1 diabetes was developed using samples obtained from multicenter and multiethnic cohorts.

Mugdha V. Joglekar
Wilson K. M. Wong
Noha Lim
ResearchOpen Access05 Jun 2025
Nature Medicine

Volume: 31, P: 2622-2631
Computational analysis of miRNA mediated KDR gene regulation and natural VEGFR2 inhibitors from Persicaria hydropiper in hepatocellular carcinoma

Sk. Faisal Ahmed
Sunbin Samin
Tithi Mondal
ResearchOpen Access30 Oct 2025
Scientific Reports

Volume: 15, P: 1-24
Epigenetic regulation of AURKA by miR-4715-3p in upper gastrointestinal cancers

Ahmed Gomaa
Dunfa Peng
Wael El-Rifai
ResearchOpen Access18 Nov 2019
Scientific Reports

Volume: 9, P: 1-11
The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice

Minamizaki et al. show that osteoblast-specific overexpression of miR-125b, a cargo of matrix vesicles, increases the bone mass from a reduced number of osteoclasts in mice. This study suggests that bone matrix stores miR-125b which inhibits bone resorption by downregulating PRDM1, a transcriptional repressor of anti-osteoclastogenic factors.

Tomoko Minamizaki
Yuko Nakao
Yuji Yoshiko
ResearchOpen Access16 Jan 2020
Communications Biology

Volume: 3, P: 1-11
Circulating miR-141 and miR-375 are associated with treatment outcome in metastatic castration resistant prostate cancer

A. H. Zedan
P. J. S. Osther
T. F. Hansen
ResearchOpen Access14 Jan 2020
Scientific Reports

Volume: 10, P: 1-9
Sustainable UV approaches backed by one step extraction procedure for quantifying the newly released mirabegron and silodosin mixture in urine

Ahmed R. Mohamed
Sara El‑Hanboushy
Eman Darweish
ResearchOpen Access14 Aug 2025
Scientific Reports

Volume: 15, P: 1-12
Exploring a Role for Regulatory miRNAs In Wound Healing during Ageing:Involvement of miR-200c in wound repair

Eerik Aunin
David Broadley
Natalia V. Botchkareva
ResearchOpen Access12 Jun 2017
Scientific Reports

Volume: 7, P: 1-10
Evaluation of tumorigenesis-related miRNAs in breast cancer in Egyptian women: a retrospective, exploratory analysis

Ghada M. Salum
Nesma M. Elaraby
Reham M. Dawood
ResearchOpen Access29 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Molecular detection of exosomal miRNAs of blood serum for prognosis of colorectal cancer

Tahani Bakhsh
Safiah Alhazmi
Ahmed Bahieldin
ResearchOpen Access17 Apr 2024
Scientific Reports

Volume: 14, P: 1-21
Plasma extracellular vesicle miRNAs as potential biomarkers of superstimulatory response in cattle

Ahmed Gad
José María Sánchez
Pat Lonergan
ResearchOpen Access05 Nov 2020
Scientific Reports

Volume: 10, P: 1-16
Impact of Micro-RNAs as biomarkers for end-stage renal disease related to hypertension and diabetes

Ali Ata
Doaa Ezzat
Weaam Gouda
ResearchOpen Access24 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration

The Iberian ribbed newt Pleurodeles waltl has a wide spectrum of regeneration abilities. Here, Elewa et al. sequence its ~20 Gb genome and transcriptome to investigate the molecular features underlying its regenerative capacities.

Ahmed Elewa
Heng Wang
András Simon
ResearchOpen Access22 Dec 2017
Nature Communications

Volume: 8, P: 1-9
Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer

Lijun Zhou
Mei Liu
Xiangdong Li
Research17 Nov 2025
Oncogene

Volume: 44, P: 4765-4780
Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma

Elham Ali
Marwa Adel Ahmed
Menha Swellam
ResearchOpen Access14 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Vesicle miR-195 derived from Endothelial Cells Inhibits Expression of Serotonin Transporter in Vessel Smooth Muscle Cells

Junzhong Gu
Huiyuan Zhang
Yuchun Gu
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
Small non-coding RNA landscape of extracellular vesicles from human stem cells

Sippy Kaur
Ahmed G. Abu-Shahba
Bettina Mannerström
ResearchOpen Access19 Oct 2018
Scientific Reports

Volume: 8, P: 1-18
In silico approaches unveil the mechanism of action of Eclipta prostrata against acute myeloid leukemia

K.M. Tanjida Islam
Md. Muzahidul Islam
Shahin Mahmud
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-28
Expression deregulation of mir31 and CXCL12 in two types of oral precancers and cancer: importance in progression of precancer and cancer

Esita Chattopadhyay
Richa Singh
Bidyut Roy
ResearchOpen Access06 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories

The overexpression of β-catenin and the transcription factor Gata4 in skin fibroblasts induces these cells to secrete reparative exosomes, as shown in mice models of myocardial infarction and Duchenne muscular dystrophy.

Ahmed G. E. Ibrahim
Chang Li
Eduardo Marbán
Research26 Aug 2019
Nature Biomedical Engineering

Volume: 3, P: 695-705
A multi-omics approach for biomarker discovery in neuroblastoma: a network-based framework

Rahma Hussein
Ahmed M. Abou-Shanab
Eman Badr
ResearchOpen Access17 May 2024
npj Systems Biology and Applications

Volume: 10, P: 1-14
MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans

Anusha Angajala
Hughley Raymond
Clayton Yates
ResearchOpen Access22 Dec 2022
Scientific Reports

Volume: 12, P: 1-14
Association of GAS6, AXL, and GAS6-AS lncRNAs with nephropathy in Egyptian patients with type 2 diabetes mellitus: a case–control observational study

Tarek Kamal Motawi
Dina Sabry
Nancy Nabil Shahin
ResearchOpen Access13 Nov 2025
Nutrition & Diabetes

Volume: 15, P: 1-10
Optimizing irrigation and nitrogen levels for improved soil nitrogen dynamics and use efficiency in temperate ecology of Kashmir

Mohd Salim Mir
Waseem Raja
Samy Sayed
ResearchOpen Access30 Dec 2025
Scientific Reports

Volume: 16, P: 1-16
Linagliptin and telmisartan induced effects on renal and urinary exosomal miRNA expression in rats with 5/6 nephrectomy

Denis Delić
Franziska Wiech
Thomas Klein
ResearchOpen Access25 Feb 2020
Scientific Reports

Volume: 10, P: 1-15
Bioinformatic prediction, annotation and experimental validation of conserved microRNAs in Lactuca sativa Linn

Shehnaz Shair Qambrani
Muhammad Naeem Shahwani
Asma Abro
ResearchOpen Access12 Aug 2025
Scientific Reports

Volume: 15, P: 1-10
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Differential analysis of histopathological and genetic markers of cancer aggressiveness, and survival difference in EBV-positive and EBV-negative prostate carcinoma

Khalid Ahmed
Alisalman Sheikh
Syed Hani Abidi
ResearchOpen Access05 May 2024
Scientific Reports

Volume: 14, P: 1-17

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