Search

2D p-type transistors are essential for the realization of complementary circuits for post-silicon electronics. Here, the authors report a chloroform doping strategy to fabricate p-type monolayer WSe₂ transistors with high performance and long-term stability.

Combining high-resolution microscopic techniques with luminescent probes is important for biological imaging. Here, Mi et al. demonstrate subwavelength imaging by combining lanthanide-doped upconversion nanocrystals with ionoluminescence, revealing cellular structure and particle spatial distribution at high resolution.

The combination of JWST and ALMA data here unravel the history of the gas content of a quiescent galaxy, which became quenched through an act of self-sabotage. Black-hole accretion feedback heated the galaxy’s surrounding material, preventing its accretion.

Guided by density functional theory, a commercially viable refractory alloy is developed, which exhibits excellent room-temperature ductility and strength, and high strength at elevated temperatures.

Imaging live cells at nanometre resolution is challenging because radiation damage kills the cells during exposure. Here, the authors overcome this difficulty in a ‘diffraction before destruction’ experiment using an X-ray laser and record signal to 4 nm resolution on a free-flying cell.

High-resolution flare footpoint observations in the extreme ultraviolet and X-rays were taken by Solar Orbiter. Combined with simulations, the results reveal that the dominant mechanism carrying flare energy through the Sun’s atmosphere can vary on small spatial scales.

Coordinated X-ray and radio observations reveal that disk winds and jets occur mutually exclusively in 4U 1630–472, providing new observational constraints on the interplay between different modes of outflow in X-ray binaries.

A neuromorphic sensing system combining a flexible piezoelectric sensor array, event-triggered circuitry and a memristive chip enables energy-efficient, low-latency edge processing of event-based data through analogue in-memory computing.

Tomographic reconstructions of cryopreserved specimens enable in-situ structural studies. Here, the authors present the beam image-shift electron cryo-tomography (BISECT) approach that accelerates data collection speed and improves the map resolution compared to earlier approaches and present the in vitro structure of a 300 kDa protein complex that was solved at 3.6 Å resolution as a test case.

Generation of orbital currents in a non-magnetic material can be useful to build efficient orbitronic devices. Now, the interplay of chiral phonons and electrons is shown to produce orbital currents in α-quartz.

Andersen et al. have demonstrated a new type of beam steering device based on the excitonic response of an atomically thin semiconductor. Using electrostatic gates, the authors achieved tunable steering with switching times on the nanosecond scale.

¹³⁴Ce and ¹³⁴La have great potential as companion diagnostic isotopes for radiotherapeutics labelled with α-emitting ²²⁵Ac and ²²⁷Th. Now, by controlling the Ce^III/Ce^IV redox couple, the large-scale production, purification and characterization of ¹³⁴Ce- and ¹³⁴La-based radiolabels has been achieved and their use for in vivo positron emission tomography is demonstrated.

The use of a needle-shaped optical beam improves the depth of field for photoacoustic imaging.

Customizing the output from a laser is typically done by appropriate optical elements. Here Ngcobo et al.show that a digitally controlled holographic mirror placed within the laser cavity can be used to dynamically select the desired laser output modes.

Better understanding the synergy between radiation and corrosion is necessary to deploy advanced nuclear reactors. Here, the authors contradict the misconception that radiation always results in deleterious effects and show that proton irradiation slows the corrosion of Ni-Cr alloys in 650 °C molten salt.

2D semiconductors are attracting attention as a potential alternative for post-silicon electronics, but the fabrication of high-performance 2D p-type transistors remains a challenge. Here, the authors report the realization of bilayer WSe₂ p-type transistor arrays with on-state currents up to 421 μA/μm, on/off ratios exceeding 10⁷ and subthreshold swings as low as 75 mV/decade.

Ghatbale et al. adapted a co-evolutionary technique to develop Klebsiella pneumoniae phages to be highly active longitudinally against K. pneumoniae clinical isolates, including drug resistant isolates.

Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it.

Optical control of atomic quantum systems poses stringent requirements on modulators. Here, the authors present a piezoelectrically actuated silicon-nitride-based high-speed spatial light modulator technology meeting those needs.

Previous work has shown the detection of quantum turbulence with mechanical resonators but with limited spatial and temporal resolution. Here, the authors demonstrate real-time detection of single quantum vortices in superfluid ⁴He with millisecond and micron resolution at temperatures of 10 millikelvin.

Improved vaccines and antivirals are needed for many enveloped viruses. Here, the authors identify sulfur-based small molecules that disrupt viral membrane properties, inhibiting fusion and entry, and safely inactivate influenza virus. The resulting inactivated influenza vaccine is protective in mice.

By exploiting geometric phase control inside a laser cavity to map polarization to orbital angular momentum, a new class of laser that is able to generate all states on the higher-order Poincaré sphere is reported.

Resonant dispersive wave (RDW) emission enables tunable few-femtosecond UV pulses which can be useful for ultrafast science. Here, the authors investigate ultrafast relaxation and structural evolution of morpholine with enhanced temporal resolution, following excitation via RDWs.

Using terahertz spectroscopy and ultrafast electron diffraction, the paper shows how the DC conductivity of warm dense matter depends on material phase. This provides insight to how electron scattering processes impact conductivity in this regime.

Entanglement between photons is easily destroyed by losses in optical systems as light propagates through it. For entanglement of orbital angular momentum, McLaren et al.show that losses caused by obstructions in the beam path can be overcome if measurements are made in the Bessel basis.

MYC-driven medulloblastoma is highly aggressive and associated with poor survival. Here, the authors perform single nuclei multi-omic analysis of matched primary and recurrent tumours and identify potential resistance mechanisms and targetable pathways.

Fast panoramic rotational ultrasound tomography and photoacoustic tomography are integrated for hybrid rotational ultrasound and photoacoustic tomography, for three-dimensional dual-contrast imaging of soft tissue and vasculature across the human body.

Researchers demonstrate systems in which optical solitons coexist and interact with topological solitonic structures localized in the molecular alignment field of a soft birefringent medium. The findings could lead to solitonic tractor beams and new light–matter self-patterning phenomena.

A 300-Gbit/s free-space optical communication system is demonstrated in the mid-IR wavelength region by using both wavelength- and mode-division multiplexing.

This study introduces 3D-PanoPACT, a panoramic photoacoustic imaging system enabling high spatiotemporal-resolution visualization of whole-body dynamics and metabolism, overcoming limitations in speed and field of view for advanced 3D tomography.

Nonlinear absorption of helical light beams offers a new chiroptical detection scheme for both chiral and achiral molecules in liquid phase.

Achieving nonlinear optical response of free-space planar solid devices in the few-photon regime will provide several technological advances. Here, the authors demonstrate a self-hybridised perovskite metasurface with strong nonlinear absorption at record low incident powers, by means of cavity critical coupling engineering

Multilayer-grating-based spectrometer with high photon flux and moderate energy resolution for tender X-ray

Lenses are well-understood optical instruments to focus light. The flame lens realized here by Michaelis et al. offers light focusing with a damage threshold several orders of magnitude higher than that of most conventional lenses.

Retarder arrays enable advanced photonic applications but are limited by controllable flexibility. Here, authors demonstrate a compound modulator that creates synthetic tuneable retarder arrays, offering unprecedented dynamic control of light, enabling new beam generation, analysis, and correction.

The downscaling process of conventional static random-access memory (SRAM) cells has recently slowed down, posing challenges for future electronic devices. Here, the authors demonstrate ~40% reduction in cell area and improved interconnect length for 2-tier 3D-integrated SRAM cells based on 2D MoS₂ transistors.

Lateral heterojunctions between two-dimensional semiconductor crystals are essential building blocks for electronic devices. Here, the authors utilize electron-beam lithography and selective conversion to simultaneously fabricate arrays of molybdenum diselenide–molybdenum disulfide heterojunctions.

Ptychography computationally reconstructs high-resolution images from overlapping diffraction patterns, recovering both amplitude and phase information. This Primer covers the technique’s principles, diverse wavelength implementations from optical to electron regimes, advanced reconstruction strategies and applications ranging from live cell imaging to atomic-resolution materials characterization.

Despite exhibiting ferroelectric features, SrTiO₃ fails to display long-range polar order at low temperatures due to quantum fluctuations. An ultrafast X-ray diffraction experiment now probes polar dynamics of this material at the nanometre scale.

A waveguide can increase the coupling between an electron beam and electromagnetic field in a THz Free Electron Laser. The authors characterize the spectral properties of a compact waveguide FEL including dual-frequency lasing and tunable wavelength.

A materials platform using tantalum as a base layer and silicon as the substrate to construct superconducting qubits enables device performance improvements such as millisecond lifetimes and coherence times, as well as high time-averaged quality factors.

Psoriasis is a difficult to treat chronic skin condition that could be limiting to quality of life. Here, authors present results of the phase 2 randomized clinical trial KNOCKOUT (NCT05283135) in which they treated patients with moderate-to-severe plaque psoriasis with higher-than-approved doses of risankizumab, an interleukin-23 inhibitor, to show high skin clearance rates and decreased tissue resident memory T cell numbers in the lesional skin.

The authors present an integrated acousto-optic modulator fabricated in a wafer-scale process that realizes efficient, high-speed modulation of visible light with high optical power handling.

This Review examines the bidirectional relationship between mental health conditions, particularly depression, anxiety and severe mental illness, and chronic kidney disease. The authors discuss the impact of these comorbid conditions; provide insights and recommendations on patient management, with a focus on integrated care; and highlight key research gaps.