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Single-cell analysis of B cells and their niches reveals gene regulation dynamics, developmental heterogeneity, cell-cell interactions, and age-associated B cell subpopulations with distinct secretory phenotypes.

This study shows that the rapid advancement of China’s urban sustainable development process has significantly reduced urban vulnerability, narrowing the gap in comprehensive humid-heat risk between urban and rural areas.

This study provides a cellular atlas of A. annua glandular trichomes using single-nucleus and spatial transcriptomics. It defines three developmental states and identifies hundreds of hub genes for trichome morphogenesis and artemisinin synthesis.

A ductile inorganic-rich solid–electrolyte interphase that retains its structural integrity and allows easy ion diffusion enables a long cycle life under practical conditions for lithium metal batteries.

High-voltage non-aqueous lithium metal batteries suffer from poor cycling stability due to the presence of impurities in the electrolyte solution. Here, the authors report lithium hexamethyldisilazide to scavenge HF and H₂O, prevent the Ni dissolution and suppress side reactions during cycling.

A Gd@C₈₂ molecule shows electric polarization switching behaviour under a gate bias voltage, thus demonstrating a single-molecule electret device.

Superconductivity is demonstrated in an infinite-layer nickelate similar to infinite-layer copper oxides, which is synthesized using soft- chemistry topotactic reduction of the perovskite precursor phase.

A type II supernova (SN 2023ixf) was observed in the galaxy M101 at a distance of 6.85  ±  0.15 Mpc, at about 1.0  h after the explosion.

The kiwifruit is an economically and nutritionally important fruit crop with high vitamin C content. Here, the authors report the draft genome sequence of a heterozygous kiwifruit and through comparative genomic analysis provide valuable insight into kiwifruit evolution.

Oxygen vacancies significantly influence the electronic and optical properties of oxide films, affecting the performance of photodetectors and power devices. However, their role in metastable materials such as κ-Ga₂O₃ remains underexplored. In this study, we apply hybrid density functional theory to investigate the thermodynamic, electronic, and optical properties of oxygen vacancies in κ-Ga₂O₃, revealing that they create a deep donor defect in the bandgap, which in turn affects both defect levels and optical transition energies due to Ga displacement

Superluminous supernova SN 2017egm has a complex light curve that is well modelled by successive collisions of a shockwave with dense circumstellar shells ejected by its massive progenitor star during the pair-instability pulsation stage. Such a scenario might be responsible for providing a power source for superluminous supernovae in general.

Both reusability and sensing capability of biosensors are required but usually challenging to achieve. Here a reusable and highly sensitive epidermal growth factor receptor sensor based on a drug-mediated organic electrochemical transistor is reported.

Solid polymer electrolytes suffer from limited ionic conductivity and poor interfacial stability for lithium batteries. Here, authors propose a fluorinated ether diluent to reduce the dipole-dipole interaction of ionic solvate with the polymer matrix and induce the formation of aggregates.

A very uncommon detached binary system with a 20.5-min orbital period has been discovered to harbour a carbon–oxygen white dwarf star and a low-mass subdwarf B star with a seven-Earth radius that traces the theoretical limit of binary evolution predicted 20 years ago.

Blue large-amplitude pulsators (BLAPs) represent a mysterious class of hot stars pulsating in an unexpectedly extreme way. Here we report the discovery of an unusual BLAP at a short-lived phase that provides a new path to understand their physical origins.

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Measurements of four different infinite-layer nickelates show that magnetic behaviour coexists with superconductivity. This is different from what is seen in cuprates, giving a strong distinction between the two classes of oxide superconductors.

In this work, authors report on SCIMP-positive exosomes secreted by macrophages, that play a crucial anti-inflammatory role in pneumonia. Exosomal SCIMP primarily achieves bacterial clearance by the SCIMP-FPRs-neutrophils chemotaxis.

While water splitting in acid offers higher operational performances than in alkaline conditions, there are few high-activity, acid-stable oxygen evolution electrocatalysts. Here, authors examine electrochemical Li intercalation to improve the activity and stability of RuO₂ for acidic water oxidation.

High yields of methanol are difficult to achieve with direct oxidation of methane to methanol. Here the authors report a high methanol space-time yield which is attributed to the confinement effect of 6-membered ring voids and the isolated Cu-OH single sites in SSZ−13 zeolite.

The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.

Cai et al. show that YAP forms liquid-like condensates in the nucleus that compartmentalize YAP’s DNA binding cofactors and transcription co-activators to induce transcription of YAP-specific proliferation genes.

The authors developed a highly conductive and dielectric composite solid-state electrolyte by coupling BaTiO₃ and Li_0.33La_0.56TiO_3–x nanowires with a side-by-side heterojunction structure in a polyvinylidene difluoride matrix, which simultaneously promotes the dissociation of lithium salts to produce more movable Li ions and efficiently transports the generated movable Li ions.

Developing hybrid rice cultivars requires time consuming random crossing. Here, the authors develop a new next generation sequencing-based quantitative trait locus mapping method to dissect heterotic gene OsMADS1 and demonstrate the feasibility of pyramiding two genes to achieve large heterotic effect.

Biopsy is recommended for definitive diagnosis of liver carcinoma, however, this process requires staining and expert pathologists to confirm diagnosis. Here, the authors employ a portable Raman spectroscopy system combined with deep learning to detect carcinoma from normal tissue in real time.

Genome-wide analysis identifies 30 loci associated with bipolar disorder, allowing for comparisons of shared genes and pathways with other psychiatric disorders, including schizophrenia and depression.

Here the authors show a beta alumina nanowires/gel polymer composite electrolyte design. The dense and homogeneous solid-liquid hybrid sodium-ion transportation channels promote uniform sodium deposition and stripping and significantly improve the performance of a Na metal battery.

Microflow catalysis represents a cutting-edge method for advancing chemical synthesis and manufacturing, though developing efficient and stable multiphase catalysts remains challenging. Here the authors demonstrate the incorporation of amine-containing metal-organic cages into automated microfluidic reactors through covalent bonds, facilitating highly continuous flow catalysis.

Aphid-transmitted viruses encode proteins that suppress the plant airborne defence response—which is triggered by volatile chemicals released by neighbouring plants after aphid attack—and the plants consequently become less repellent to aphids and more suitable for aphid survival, infestation and viral transmission.

High-resolution cryo-EM structures of Chlamydomonas light-harvesting complex II (LHCII)–photosystem II (PSII) supercomplexes show loosely and moderately associated LHCIIs forming multiple pathways for energy transfer to PSII reaction centres.

Measurements of a superconducting infinite-layer nickelate show that its upper critical field is largely isotropic despite its quasi-two-dimensional structure. This indicates that, unusually for layered oxides, the superconductivity is Pauli-limited.

Low-temperature ultraclean integration of large-area MoS₂ thin-film transistors with nitride micro-LEDs through a back end of line process enables the demonstration of displays with high resolution and uniformity.

Ring-opening polymerizations of α-amino acid N-carboxyanhydrides to form polypeptides are usually sensitive to moisture, slow and can undergo side reactions. Here the authors use lithium hexamethyldisilazide to initiate α-amino acid N-carboxyanhydride polymerizations that is very fast and can be conducted in an open vessel.