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Showing 51–83 of 83 results

Advanced filters: Author: Dongsheng Zhu Clear advanced filters

A versatile CRISPR/Cas9 system off-target prediction tool using language model

CCLMoff is a deep learning framework that leverages RNA language modeling for accurate CRISPR/Cas9 off-target prediction, demonstrating strong generalization across datasets and advancing computational sgRNA design.

Weian Du
Liang Zhao
Dongsheng Tang
ResearchOpen Access06 Jun 2025
Communications Biology

Volume: 8, P: 1-10
Thioredoxin-1 inhibits NLRP3-mediated pyroptosis by regulating TXNIP in models of Alzheimer’s disease

Jinjing Jia
Zixuan Sheng
Hongjun Liu
ResearchOpen Access13 May 2025
Scientific Reports

Volume: 15, P: 1-14
hsa-miR-199b-3p suppresses osteosarcoma progression by targeting CCDC88A, inhibiting epithelial-to-mesenchymal transition, and Wnt/beta-catenin signaling pathway

Dongsheng Zhu
Han Qi
Hongqi Zhu
ResearchOpen Access02 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Theoretical framework and reliability verification of the loaded three-zone structural model in coal mine overburden strata

Yi Liu
Quanjie Zhu
Dongsheng Jiang
ResearchOpen Access09 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Chromosome-level genome assembly and annotation of the tropical sea cucumber Bohadschia ocellate

Qianying Huang
Xuan Wang
Aifen Yan
ResearchOpen Access17 Dec 2025
Scientific Data

Volume: 13, P: 1-12
Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth

Youwei Li
Wei Wang
Dongsheng Guo
ResearchOpen Access13 Jan 2023
Cell Death & Disease

Volume: 14, P: 1-15
SPA inhibits hBMSC osteogenic differentiation and M1 macrophage polarization by suppressing SETD2 in acute suppurative osteomyelitis

Dongsheng Zhu
Feng Chen
Han Qi
ResearchOpen Access03 Jun 2024
Scientific Reports

Volume: 14, P: 1-13
Multi-kingdom microbial changes and their associations with the clinical characteristics in schizophrenia patients

Baoyuan Zhu
Liqin Liang
Kai Wu
ResearchOpen Access05 Jul 2025
Translational Psychiatry

Volume: 15, P: 1-14
First-line penpulimab (an anti-PD1 antibody) and anlotinib (an angiogenesis inhibitor) with nab-paclitaxel/gemcitabine (PAAG) in metastatic pancreatic cancer: a prospective, multicentre, biomolecular exploratory, phase II trial

Huizi Sha
Fan Tong
Juan Du
ResearchOpen Access07 Jun 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-10
Propranolol accelerates adipogenesis and inhibits endothelium differentiation of HemSCs via suppressing HK2 mediated glycolysis

Tianshuang Zhu
Peipei Wang
Yu Cai
Research17 May 2025
Pediatric Research

Volume: 99, P: 351-361
IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis

Ningyu Zhu
Xia Wang
Shuyi Si
ResearchOpen Access28 Nov 2018
Scientific Reports

Volume: 8, P: 1-9
Gilgamesh is required for the maintenance of germline stem cells in Drosophila testis

Dongsheng Chen
Xiangxiang Zhu
Yuelin Gu
ResearchOpen Access18 Jul 2017
Scientific Reports

Volume: 7, P: 1-9
A ‘suicide’ CRISPR-Cas9 system to promote gene deletion and restoration by electroporation in Cryptococcus neoformans

Yu Wang
Dongsheng Wei
Xudong Zhu
ResearchOpen Access09 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
Multi-level genomic analyses suggest new genetic variants involved in human memory

Zijian Zhu
Biqing Chen
Yi Rao
Research03 Jul 2018
European Journal of Human Genetics

Volume: 26, P: 1668-1678
ALKBH4 impedes 5-FU Sensitivity through suppressing GSDME induced pyroptosis in gastric cancer

Xin Jiang
Zhiman Zhu
Dongsheng Pei
ResearchOpen Access20 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-16
Tertiary lymphoid structures in diseases: immune mechanisms and therapeutic advances

Lianyu Zhao
Song Jin
Haiwei Wu
ReviewsOpen Access28 Aug 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-43
Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels

Jin Wang
Minglin Wang
Qiuran Xu
ResearchOpen Access12 Sept 2024
Oncogenesis

Volume: 13, P: 1-11
Heritability of human visual contour integration—an integrated genomic study

Zijian Zhu
Biqing Chen
Fang Fang
Research30 Jul 2019
European Journal of Human Genetics

Volume: 27, P: 1867-1875
A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion

Zijian Zhu
Biqing Chen
Fang Fang
Research16 Sept 2020
Journal of Human Genetics

Volume: 66, P: 261-271
A MYST Histone Acetyltransferase Modulates Conidia Development and Secondary Metabolism in Pestalotiopsis microspora, a Taxol Producer

Qian Zhang
Oren Akhberdi
Xudong Zhu
ResearchOpen Access29 May 2018
Scientific Reports

Volume: 8, P: 1-11
Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity

Biqing Chen
Zijian Zhu
Yi Rao
Research26 Feb 2018
Journal of Human Genetics

Volume: 63, P: 605-619
Inhibition of nuclear receptor RORα attenuates cartilage damage in osteoarthritis by modulating IL-6/STAT3 pathway

Tongzhou Liang
Taiqiu Chen
Dongsheng Huang
ResearchOpen Access28 Sept 2021
Cell Death & Disease

Volume: 12, P: 1-13
Differentiation of intestinal tuberculosis and Crohn’s disease through an explainable machine learning method

Futian Weng
Yu Meng
Jianping Zhu
ResearchOpen Access02 Feb 2022
Scientific Reports

Volume: 12, P: 1-12
Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress

Yue Zhao
Qinglong Guo
Na Lu
ResearchOpen Access31 May 2019
Mucosal Immunology

Volume: 12, P: 1150-1163
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model

Jesus Campagna
Patricia Spilman
Varghese John
ResearchOpen Access04 Dec 2018
Scientific Reports

Volume: 8, P: 1-15
Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b

Jingbo Dai
Zhaoxia Wang
Zhongdong Qiao
ResearchOpen Access04 Aug 2017
Scientific Reports

Volume: 7, P: 1-15
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies

Liang Guo
Qionglei Mao
Yichang Jia
ResearchOpen Access04 May 2023
Cell Research

Volume: 33, P: 497-515
Photoluminescence of a single complex plasmonic nanoparticle

Tianyue Zhang
Guowei Lu
Qihuang Gong
ResearchOpen Access27 Jan 2014
Scientific Reports

Volume: 4, P: 1-7
Hedyotis diffusa–Sculellaria barbata (HD–SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis

Danye Zhu
Shanmin Yuan
Cong Chen
ResearchOpen Access16 Aug 2023
Scientific Reports

Volume: 13, P: 1-11
Endoplasmic reticulum stress is attenuated by glycolysis in lymphatic malformations

Xuecong Li
Wenqun Zhong
Yu Cai
Research06 May 2024
Pediatric Research

Volume: 96, P: 1210-1219
Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

Jun Lan
Xinheng He
Xinquan Wang
CorrespondenceOpen Access13 Apr 2022
Cell Research

Volume: 32, P: 593-595
Spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology

Recent progress in spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology has been summarized, including not only the static arrangement of inorganic nanoparticles but also the dynamic regulation of organic and biological units at a nanometer scale.

Zhongqiang Yang
Huajie Liu
Dongsheng Liu
ReviewsOpen Access27 Feb 2015
NPG Asia Materials

Volume: 7, P: e161
Roles of tRNA metabolism in aging and lifespan

Zheng Zhou
Bao Sun
Meng Bian
ReviewsOpen Access26 May 2021
Cell Death & Disease

Volume: 12, P: 1-11

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A versatile CRISPR/Cas9 system off-target prediction tool using language model

Thioredoxin-1 inhibits NLRP3-mediated pyroptosis by regulating TXNIP in models of Alzheimer’s disease

hsa-miR-199b-3p suppresses osteosarcoma progression by targeting CCDC88A, inhibiting epithelial-to-mesenchymal transition, and Wnt/beta-catenin signaling pathway

Theoretical framework and reliability verification of the loaded three-zone structural model in coal mine overburden strata

Chromosome-level genome assembly and annotation of the tropical sea cucumber Bohadschia ocellate

Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth

SPA inhibits hBMSC osteogenic differentiation and M1 macrophage polarization by suppressing SETD2 in acute suppurative osteomyelitis

Multi-kingdom microbial changes and their associations with the clinical characteristics in schizophrenia patients

First-line penpulimab (an anti-PD1 antibody) and anlotinib (an angiogenesis inhibitor) with nab-paclitaxel/gemcitabine (PAAG) in metastatic pancreatic cancer: a prospective, multicentre, biomolecular exploratory, phase II trial

Propranolol accelerates adipogenesis and inhibits endothelium differentiation of HemSCs via suppressing HK2 mediated glycolysis

IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis

Gilgamesh is required for the maintenance of germline stem cells in Drosophila testis

A ‘suicide’ CRISPR-Cas9 system to promote gene deletion and restoration by electroporation in Cryptococcus neoformans

Multi-level genomic analyses suggest new genetic variants involved in human memory

ALKBH4 impedes 5-FU Sensitivity through suppressing GSDME induced pyroptosis in gastric cancer

Tertiary lymphoid structures in diseases: immune mechanisms and therapeutic advances

Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels

Heritability of human visual contour integration—an integrated genomic study

A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion

A MYST Histone Acetyltransferase Modulates Conidia Development and Secondary Metabolism in Pestalotiopsis microspora, a Taxol Producer

Nature vs. nurture in human sociality: multi-level genomic analyses of social conformity

Inhibition of nuclear receptor RORα attenuates cartilage damage in osteoarthritis by modulating IL-6/STAT3 pathway

Differentiation of intestinal tuberculosis and Crohn’s disease through an explainable machine learning method

Flavonoid VI-16 protects against DSS-induced colitis by inhibiting Txnip-dependent NLRP3 inflammasome activation in macrophages via reducing oxidative stress

A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model

Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b

Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies

Photoluminescence of a single complex plasmonic nanoparticle

Hedyotis diffusa–Sculellaria barbata (HD–SB) suppresses the progression of colorectal cancer cells via the hsa_circ_0039933/hsa-miR-204-5p/wnt11 axis

Endoplasmic reticulum stress is attenuated by glycolysis in lymphatic malformations

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

Spatial regulation of synthetic and biological nanoparticles by DNA nanotechnology

Roles of tRNA metabolism in aging and lifespan

Search

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