Nature Search

CDK10 suppresses nucleic acid sensors-mediated antitumor immunity

Xu et al. report that CDK10 drives immune evasion by reducing nucleic acid sensors-mediated innate immune response in tumor cells and that its inhibition improves response to immune-checkpoint blockade in preclinical cancer models.

Gaoshan Xu
Fusheng Guo
Jinfang Zhang
Research08 Jan 2026
Nature Cancer

P: 1-21
Reactive nitrogen-driven atmospheric multiphase buffering induces unintended concomitant pollution

The reactive nitrogen (Nr)-driven atmospheric multiphase buffering can induce unintended Concomitant Pollution. Given the importance of NH₃ in this process, rising global NH₃ emissions has positioned Concomitant Pollution as an urgent challenge.

Yuting Wei
Jie Gao
Armistead G. Russell
ResearchOpen Access12 Dec 2025
Nature Communications

Volume: 17, P: 1-14
iTRAQ-based quantitative analysis reveals proteomic changes in Chinese cabbage (Brassica rapa L.) in response to Plasmodiophora brassicae infection

Mei Lan
Guoliang Li
Rifei Sun
ResearchOpen Access19 Aug 2019
Scientific Reports

Volume: 9, P: 1-13
Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition

Li et al. demonstrate mitochondrial fission in macrophages as key for phagocytosis induced by therapeutic antibodies. They identify overexpression of GFPT2 as an inhibitor of the process and phase transition of the phagocytic machinery as its regulator.

Jiang Li
Yingying Ye
Shicheng Su
Research28 Apr 2022
Nature Cancer

Volume: 3, P: 453-470
Towards compute-efficient Byzantine-robust federated learning with fully homomorphic encryption

Lancelot, a compute-efficient federated learning framework using homomorphic encryption to prevent information leakage, is presented, achieving 20 times faster processing speeds through advanced cryptographic and encrypted sorting techniques.

Siyang Jiang
Hao Yang
Guoliang Xing
Research08 Sept 2025
Nature Machine Intelligence

Volume: 7, P: 1657-1668
Destruction of VISTA by TRIM25 ablation in T cells potentiates cancer immunotherapy

Yishuang Sun
Zijian Zhang
Jinfang Zhang
Research13 Nov 2025
Cell Research

Volume: 35, P: 1003-1020
9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

The molecular mechanisms of resistance to immune checkpoint therapy remain elusive. Here, the authors perform immunogenomic analysis of TCGA data and data from clinical trials for antiPD-1/PD-L1 therapy and highlight the association of 9p21 loss with a cold tumor microenvironment and resistance to therapy.

Guangchun Han
Guoliang Yang
Linghua Wang
ResearchOpen Access23 Sept 2021
Nature Communications

Volume: 12, P: 1-19
Huangqin-tang ameliorates dextran sodium sulphate-induced colitis by regulating intestinal epithelial cell homeostasis, inflammation and immune response

Ying Zou
Jiantao Lin
Honggang Chi
ResearchOpen Access16 Dec 2016
Scientific Reports

Volume: 6, P: 1-13
A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

Bacterial allosteric transcription factors can sense and respond to a variety of small molecules. Here the authors present CaT-SMelor which uses Cas12a and allosteric transcription factors to detect small molecules in the nanomolar range.

Mindong Liang
Zilong Li
Li-Xin Zhang
ResearchOpen Access14 Aug 2019
Nature Communications

Volume: 10, P: 1-9
Nanocluster superstructures assembled via surface ligand switching at high temperature

Synthesizing superstructures with precisely controlled nanoscale building blocks is challenging. Here the assembly of superstructures is reported from atomically precise Ce₂₄O₂₈(OH)₈ and other rare-earth metal-oxide nanoclusters and their multicomponent combinations. A high-temperature ligand-switching mechanism controls the self-assembly.

Grayson Johnson
Moon Young Yang
Sen Zhang
Research01 May 2023
Nature Synthesis

Volume: 2, P: 828-837
Convergence and coevolution of Hepatitis B virus drug resistance

Lamivudine treatment of hepatitis B is associated with drug-resistance mutations in the virus’ DNA polymerase. In this study, 11 patients with drug resistance are investigated and the primary mutation in the DNA polymerase shown to be essential but not sufficient for establishing drug resistance.

Hong Thai
David S. Campo
Yury Khudyakov
Research17 Apr 2012
Nature Communications

Volume: 3, P: 1-8
The landscape of promoter-centred RNA–DNA interactions in rice

The bound loci and functions of chromatin-associated RNAs remain unclear in rice. This study develops an RNA–DNA mapping method to reveal the identity and interaction patterns around active promoters within hierarchical genome architecture.

Qin Xiao
Xingyu Huang
Xingwang Li
Research03 Feb 2022
Nature Plants

Volume: 8, P: 157-170
Author Correction: LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer

Fei Li
Pengfei Dai
Dong Gao
Amendments and CorrectionsOpen Access18 Mar 2025
Cell Research

Volume: 35, P: 471-472
Estimation of the wetting induced settlement of loess soils from the wetting soil-water characteristic curve

Chang Li
Yuhui Chen
Qian Zhai
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
Digital economy, technological progress, and carbon emissions in Chinese provinces

Yuyan Shen
Guoliang Wang
Ce Shen
ResearchOpen Access03 Oct 2024
Scientific Reports

Volume: 14, P: 1-13
LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer

Fei Li
Pengfei Dai
Dong Gao
ResearchOpen Access02 Jan 2025
Cell Research

Volume: 35, P: 59-71
Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Jiaxin Ge
Ji Dai
Shuangshuang Zhang
ResearchOpen Access15 May 2025
Cell Death Discovery

Volume: 11, P: 1-12
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

Dongxin Lin and colleagues report a genome-wide association study for pancreatic cancer in Chinese populations. The authors identify five new genetic loci associated with risk of pancreatic cancer.

Chen Wu
Xiaoping Miao
Dongxin Lin
Research11 Dec 2011
Nature Genetics

Volume: 44, P: 62-66
Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA

Thomas L. Dunwell
Simon C. Dailey
Guoliang Fu
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-13
Correction to: Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Jiaxin Ge
Ji Dai
Shuangshuang Zhang
Amendments and CorrectionsOpen Access30 Jul 2025
Cell Death Discovery

Volume: 11, P: 1-2
Transcriptome analysis reveals anthocyanin regulation in Chinese cabbage (Brassica rapa L.) at low temperatures

Yun Dai
Lei Zhang
Shujiang Zhang
ResearchOpen Access15 Apr 2022
Scientific Reports

Volume: 12, P: 1-15
A case study on the bearing characteristics of a bottom uplift pile in a layered foundation

Laping He
Xuwei Chen
Zhao Long
ResearchOpen Access28 Dec 2022
Scientific Reports

Volume: 12, P: 1-14
TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism

Yuanping Hu
Meiling Zhang
Yuehua Li
ResearchOpen Access14 Mar 2017
Scientific Reports

Volume: 7, P: 1-12

Search

CDK10 suppresses nucleic acid sensors-mediated antitumor immunity

Reactive nitrogen-driven atmospheric multiphase buffering induces unintended concomitant pollution

iTRAQ-based quantitative analysis reveals proteomic changes in Chinese cabbage (Brassica rapa L.) in response to Plasmodiophora brassicae infection

Macrophage mitochondrial fission improves cancer cell phagocytosis induced by therapeutic antibodies and is impaired by glutamine competition

Towards compute-efficient Byzantine-robust federated learning with fully homomorphic encryption

Destruction of VISTA by TRIM25 ablation in T cells potentiates cancer immunotherapy

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

Huangqin-tang ameliorates dextran sodium sulphate-induced colitis by regulating intestinal epithelial cell homeostasis, inflammation and immune response

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

Nanocluster superstructures assembled via surface ligand switching at high temperature

Convergence and coevolution of Hepatitis B virus drug resistance

The landscape of promoter-centred RNA–DNA interactions in rice

Author Correction: LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer

Estimation of the wetting induced settlement of loess soils from the wetting soil-water characteristic curve

Digital economy, technological progress, and carbon emissions in Chinese provinces

LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer

Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA

Correction to: Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway

Transcriptome analysis reveals anthocyanin regulation in Chinese cabbage (Brassica rapa L.) at low temperatures

A case study on the bearing characteristics of a bottom uplift pile in a layered foundation

TIR/BB-loop mimetic AS-1 attenuates cardiac ischemia/reperfusion injury via a caveolae and caveolin-3-dependent mechanism

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