Search

The CMS experiment at CERN reports one of the highest-precision measurements of the W boson mass, finding it in line with standard model predictions and at odds with recent anomalous measurements.

Satellite observations over the Greenland Ice Sheet reveal a destructive mode of meltwater drainage whereby a subglacial flood induced by the rapid drainage of a subglacial lake burst through the surface, fracturing the ice sheet.

Physical networks can learn to accomplish tasks on the fly by adjusting their internal parameters. Now it is shown that such physical learning can be achieved in metamaterials that can learn to change shape.

Decreased brain volumes and increased NfL levels can be observed earlier than disease diagnosis in short-tandem-repeat-associated neurological diseases.

Climate and land-use change are transforming biodiversity, yet national futures remain uncertain. The study projects growing extinction debts, but suggests that sustainable low-emission pathways can limit the worst impacts on British biodiversity.

Scaling correlations, between adsorption energies of chemically related surface species, impose limits on selectivity in chemical processes, as exemplified by constraints in heterogeneous catalysis. Now it has been demonstrated that time-dependent surface polarization under oscillating potentials could overcome static scaling relationships and promote selectivity in acetylene semi-hydrogenation.

Authors perform an analysis of the patient data and risk factors to evaluate unfavorable outcomes and adverse events in adults with pulmonary tuberculosis treated with a 4-month rifapentine based regimen. Low rifapentine exposure was the most clinically significant risk factor for treatment failure and tuberculosis relapse.

XRISM spectroscopy of the nucleus of the Circinus galaxy indicates elemental abundances suggestive of a dominant enrichment from core-collapse supernovae with progenitors below 20 solar masses; more massive stars may directly collapse into black holes.

A star in a primordial dwarf galaxy has preserved the elements produced by the first generation of stars. The star lacks heavy elements but exhibits an extreme amount of carbon, suggesting that low-energy explosions can seed the initial chemistry of early galaxies.

Biological system for stable object manipulation is facilitated by a unified tactile memory system. Here, GenForce enables transferable force sensing across diverse tactile sensors using a unified representation, enhancing robot manipulation through cross-sensor transfer and multi-sensor coordination.

High hole mobilities in a polarization-induced two-dimensional hole gas at a gallium nitride/aluminium nitride interface can allow Shubnikov–de Haas oscillations of light and heavy holes to be observed in gallium nitride.

A pangenome reference for the phenotypically diverse crop sorghum aims to help accelerate future efforts to breed crops that are better adapted to changing environments.

Heterochronic human serum in a microphysiological system of hiPSC-derived white adipose tissue–liver axis allows the study of aging and rejuvenation in humans.

ANNEVO advances accurate and scalable ab initio gene annotation of evolutionarily diverse genomes using deep learning approach modeling sequence evolution and long-range dependencies and mixture of experts (MoE) architecture.

An architecture inspired by Hopfield networks based on a programmable, stable, room-temperature optoelectronic oscillator-based photonics Ising machine is introduced that can be used to efficiently address optimization and combinatorics problems.

Insulin controls adipocyte metabolism through changes in protein localisation. Here, the authors use cell-wide subcellular proteomics to uncover extensive insulin-regulated protein redistribution and identify C3ORF18 as a regulator of adipocyte insulin sensitivity.

An online experiment compared 12 brief online interventions for depression. Most improved mental health immediately, but these gains decreased over time, with only two interventions significantly reducing depression 4 weeks later.

Ion diffusion region is an indicator of active magnetic reconnection, but it had not been detected in Jupiter’s magnetosphere previously. Here, the authors show a magnetic reconnection event in Jupiter’s inner magnetosphere that presents the detection of an ion diffusion region.

This study examines long-term changes in species richness across tropical forests in the Andes and Amazon. Hotter, drier and more seasonal forests in the eastern and southern Amazon are losing species, while Northern Andean forests are accumulating species, acting as a refuge for climate-displaced species.

A qualitative analysis of two decades of policy documents from 200 countries and interviews with 46 key informants found that adoption of policies to promote physical activity has increased since 2004, but implementation remains weak because physical activity is still a low, albeit gradually increasing, political priority in most countries.

The role of mitochondrial supercomplexes in guiding redox proteins across membranes during energy conversion remains unclear. Here, authors integrate multiscale modeling and cryo-EM to examine mechanisms of electron transfer and energy conversion efficiency.

The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task in mice.

HIV-transcribing cells in people living with HIV are difficult to study with conventional single-cell RNA-seq. Here the authors develop a technique to increase detection of HIV RNA during scRNA-seq and, comparing the transcriptomes of HIV RNA+ blood cells obtained pre- and post-antiretroviral therapy, provide insights into the persistence of the HIV RNA+ reservoir.

Disease heterogeneity complicates precision medicine, which focuses on single conditions and ignores shared mechanisms. Here the authors introduce ‘pan-disease’ analysis using a deep learning model on multi-organ data, identifying 11 AI-derived biomarkers that reveal new therapeutic targets and pathways, enhancing patient stratification for disease risk monitoring and drug discovery.

Suture zones are abundant on Antarctic ice shelves and widely observed to impede fracture propagation. Here we show that fracture detainment is principally controlled by the zones’ enhanced seawater contents, reducing fracture-driving stresses by orders of magnitude and therefore greatly enhancing stability.

Using a hydrocarbon-soluble Mg⁰ complex, the heavier tetrel elements silicon, germanium, tin and lead are reduced to their ultimate negative oxidation state −IV. Despite fulfilling the octet rule, tetra-anionic tetrels are highly reactive anions which react as strong Brønsted bases, quadruple nucleophiles or eight-electron reducing agents.

Cluster synchronization in networks of coupled dynamical units is influenced by the symmetry and equitability of interaction patterns. Here, the authors demonstrate that equitability is both necessary and sufficient for the existence of linearly independent cluster synchronised solutions in multiplex and higher-order networks, explaining the prevalence of explosive synchronization and its constraints.

Brain-wide recordings in mice reveal that prior expectations are distributed through recurrent loops across all levels of cortical and subcortical processing.

Characteristic genes or proteins driving continuous biological processes are difficult to uncover from noisy single-cell data. Here, authors present DELVE, an unsupervised feature selection method to identify core molecular features driving cell fate decisions.

A 142-qubit processor can be realized by connecting two smaller quantum processors using classical communications and circuit cutting.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

A neuromorphic sensing system combining a flexible piezoelectric sensor array, event-triggered circuitry and a memristive chip enables energy-efficient, low-latency edge processing of event-based data through analogue in-memory computing.

A machine learning model that can solve nanocrystalline structures from highly degraded PXRD patterns is presented. It is shown to be successful on simulated crystals as small as 10 Å, and is robust to noisy patterns from real-world experiments.

Examples of materials with non-trivial band topology in the presence of strong electron correlations are rare. Now it is shown that quantum fluctuations near a quantum phase transition can promote topological phases in a heavy-fermion compound.

There has been a recent interest in control of magnetism via ionic transport. The appeal of such magneto-ionic control lies in its extent, non-volatility and potential energy-efficiency, however, the number of systems showing such behaviour is limited. Here, Tan, Ma, and coauthors demonstrate magneto-ionic control through Carbon transport.

Electrochemical hydrogenation drives a reversible conductor–insulator transition in graphene. Authors show that it is 10⁶× faster than other methods and tunable by isotope effects and lattice corrugations, enabling ionic control of 2D electronics.

Large-scale computational and in vitro analyses identify commensal type III secretion systems and substrates in the human gut microbiome that can interact with human proteins to modulate immune pathways.

Using multi-ancestry genome-wide association study and fine-mapping, 298 loci and 36 credible genes are identified in the aetiology of bipolar disorder.