Search

Achieving photo-thermal stability and device operational stability of tin-lead perovskite solar cells remains a major challenge. Here, authors replace tin fluoride additive by lead powders followed by lead fluoride post-treatment, achieving efficiency of 24.07% in stable tin fluoride-free devices.

The use of non-noble metal catalysts is crucial for promoting the industrialization of proton exchange membrane water electrolysis. By introducing CF₃CF₂CF₂CH₂OH into Nafion ionomer, we optimized the water channels and enhanced the stability of the Co₃O₄ catalyst at the anode

In tonal languages, modulation of pitch distinguishes words with different meaning. Here the authors investigate neural mechanisms of pitch control during lexical tone production in Mandarin-speaking participants.

Ultraviolet light damages DNA and drives skin cancer. Here, the authors show that the DNA replication factor And-1 coordinates with DNA polymerase δ to repair UV-induced lesions, and that loss of And-1 phosphorylation impairs repair and promotes skin tumorigenesis.

1,6 enynes are a useful synthetic building block, but their use asymmetric intramolecular reductive couplings with cobalt catalysts have not been well-explored. Here, the authors describe an enantioselective intramolecular reductive coupling of enynes via the combination of electrochemistry and cobalt catalysis.

Zhang, Ma et al. report that ROS-activated O-GlcNAc transferase promotes FOXK2 O-GlcNAcylation and nuclear translocation to upregulate SLC7A11 expression, thereby modulating ferroptosis sensitivity, tumour development and chemoradiotherapy efficacy.

Reconstruction of metal-organic frameworks occurs under reaction conditions, hindering mechanism understanding. Here, the authors identify the alkaline reconstructed β-Ni(OH)₂ with residual ligand that can catalyze the deprotonated anion of hydrogen peroxide at high current densities.

The exact mechanism for superconductivity in iron-based superconductors remains elusive, but is thought to involve complex interactions between many orbitals. Using angle-resolved photoelectron spectroscopy, Liuet al. report the electronic structure of the single-layer parent compound FeSe.

Whether electron–phonon coupling is a generic feature in FeSe/SrTiO₃ to enhance superconductivity remains unclear. Here, Zhang et al. report replica bands in FeSe/SrTiO₃(110), suggesting a common mechanism in FeSe on SrTiO₃with different surface terminations.

Natural deep-mantle peridotites from eastern China reveal Fe-Ni alloys and Fe³⁺-rich olivine, providing direct evidence of iron disproportionation and slab recycling from the mantle transition zone beneath the eastern Asia big mantle wedge.

A new paleosol-based CO₂ record from the Chinese Loess Plateau reveals a stepwise decline in glacial CO₂ over the past 2.6 million years and suggests that climate sensitivity remained stable across glacial–interglacial cycles.

Climate dynamics in Earth’s distant history can provide important forecasting for future changes, but uncertainties in proxy-derived carbon dioxide results are common. Here Da and colleagues present a refined paleosol proxy for carbon dioxide reconstruction, and report persistently low levels ( < 300 ppm) throughout the Pleistocene interglacials.

Metabolic, immune and endocrine systems undergo seasonal changes in animals. Here the authors report the seasonal transcriptome of 80 tissues collected over 1 year from male and female rhesus macaques as well as sex differences in seasonally oscillating genes.

Rational design of efficient electrocatalysts for oxygen evolution reaction is critical for water-alkali electrolysis. Here, the authors fabricate a NiMoN/NiFe layered double hydroxide and show the accelerated oxygen evolution kinetics are due to the heterointerface.

Rational design of single atom catalyst is critical for efficient sustainable energy conversion. Single-atomic-site ruthenium stabilized on defective nickel-iron layered double hydroxide nanosheets achieve superior HER and OER performance in alkaline media.

Chemical biology tools are critical to provide new insights into glycobiology. A protein O-glycosyltransferase, Legionella translocated protein M (LtpM), is reported as a glycoengineering tool that requires strict and short consensus sequons to probe β-O-glucosylation and O-GlcNAcylation.

While water splitting is an appealing carbon-neutral strategy for renewable energy generation, there is a need to develop new active, cost-effective catalysts. Here, authors prepare a nickel-molybdenum oxide/sulfide heterojunctions as bifunctional H₂ and O₂ evolution electrocatalysts.

The transformation of CO and H₂O into C₂₊ fuels using renewable electricity represents a significant stride in carbon recycling. Here, the authors introduce a plasma-treated Cu catalyst, achieving high CO coverage and promoted C-C coupling ability for efficient n-propanol formation.

Symptom recovery is induced by a balanced “arms race” between viruses and plants. Here, the authors show that a small peptide mediates autophagic degradation of viral silencing suppressors to reach the balance of virus pathogenicity and plant immunity.

The reversible transformation of a nanohelix is one of the most exquisite and important phenomenon in nature but nanomaterials usually fail to twist into helical crystals or untwist. Here, the authors report a reciprocal effect between molecular geometry and crystal structure which triggers a twisting-untwisting-retwisting cycle for tri-cobalt salicylate hydroxide hexahydrate.

Bacteria can use type VI secretion systems (T6SSs) to inject toxic effector proteins into adjacent cells, in a contact-dependent manner. Here, the authors provide evidence of contact-independent killing by a T6SS effector that is secreted into the extracellular milieu and then taken up by other bacterial cells.

Tuning the spintronic structure in oxygen evolution reactions is underexplored, despite its potential to enhance catalytic performance. Here, the authors report a ruthenium-cobalt-tin oxide with an optimized spintronic structure, highlighting its improved performance and reaction mechanisms.

Lignin valorization has long been hindered by the challenge of precisely controlling product selectivity. Here, the authors construct a robust electrocatalytic system that enables pH-driven switching between depolymerization and hydrogenation pathways with high selectivity.

Based on differently-oriented MAPbBr3 single-crystal wafers, the authors revealed anisotropic carrier dynamics by using angle-resolved pump-probe technique, and the microstructural mechanism of the femtosecond laser-induced emission enhancement

Depletion of calcium from intracellular stores induces interaction between the endoplasmic reticulum STIM1 protein and the plasma membrane ORAI1 channel that facilitates cellular calcium entry. Here Ma et al. characterize a STIM1 gain-of-function mutant and propose a conformational switch that controls ORAI1 gating.

In this study, the authors develop a comprehensive taxonomy of brain-wide SPNs, identifying several novel subsets via their transcriptional signatures.

Antiferromagnetic materials are potentially useful for spintronic applications. Here, the authors report high thermoelectric power value of 390 μV/K Seebeck coefficient in IrMn-based half magnetic tunnel junctions at room temperature.

This study reveals the autocatalytic growth of Li₂S crystals at the solid-liquid interface in lithium-sulfur batteries enabling good electrochemical performance under high loading and low electrolyte conditions.

Establishing robust structure/performance correlations is critical for the development of single-atom-catalysts with improved activity. Here, the axial ligand on Pt single-atom-catalyst is precisely adjusted and studied, showing that the ligand’s first electron affinity is crucial for the catalysis.

Functional divergence of CYP76AK subfamily, accompanied by oxidation variations at C-20, leads to diverse abietane-type diterpenoids in Salvia species. Enzyme activity loss contributes to this unique chemical diversity within the lineage.

Asymmetric hydrophosphorylation of unsaturated compounds is a straightforward and atom-economic approach to obtaining chiral organophosphorus compounds. Herein, the authors describe a Pd-catalzyed ligand controlled regiodivergent and enantioselective hydrophosphorylation of styrenes.

Short tandem repeat mutations in a primate Alu element on chromosome 15q cause activation of a thyroid-specific enhancer, upregulating MIR7-2/MIR1179. This results in defective thyroid proliferation and thyrotropin resistance.

Treatment with the oncolytic herpes virus CAN-3110 is associated with improved survival responses in patients with recurrent glioblastoma, particularly in individuals who are seropositive for HSV1.

Different languages rely on different vocal sounds to convey meaning. Here the authors show that language-general coding of pitch occurs in the non-primary auditory cortex for both tonal (Mandarin Chinese) and non-tonal (English) languages, with some language specificity on the population level.

Through-plane conductivity in anion-exchange membranes is beneficial for their use in fuel cells as it aids movement of ions from cathode to anode. Liu and colleagues use ferrocenium polymers and an applied magnetic field to orient ion channels appropriately and achieve improvements in stability by formation of magnetically induced mixed-valence states.

Osteoclast differentiation is critical for bone homeostasis. The authors show the negative feedback regulation of BRD9-mediated chromatin remodeling on osteoclastogenesis via interferon beta signaling and its therapeutic potential for bone diseases.

The impact of chemical chirality on immune response attracts attention in cancer vaccine design recently. Here this group reports the chirality of poly(γ-ethyl-D-glutamate)-based hydrogel exhibiting higher levels of suppression on antigen-presenting cells and inducing stronger T cell exhaustion than L-Gel eventually leading to insufficient anti-tumor efficacy.

CRISPR-Cas9 genome editing systems have great potential in cancer therapy. Here the authors report a gene-editing delivery system using functionalized nanovesicles derived from E. coli protoplasts to encapsulate Cas9-sgRNA ribonucleoprotein for the selective targeting of Pik3cg in tumor associated macrophages.

The inability to access well-defined polysaccharides in sufficient quantities has hampered our understanding of their structure–function relationships. Now it has been shown that native precision polysaccharides can be readily prepared via living polymerization of 1,6-anhydrosugars. The obtained polymers display excellent chemical recyclability, suggesting their potential utility as a class of sustainable materials.

Targeting CDK4/6 in breast cancer has been demonstrated to be initially effective but often, resistance develops. Here, the authors identify microphthalmia-associated transcription factor-A (MITF-A) as a driver of CDK4/6 inhibitor resistance in breast cancer and show that MITF-A activity is mediated through O-GlcNAcylation at Serine 49, promoting its nuclear import.

The stability of perovskite solar cell remains the biggest challenge that hinders its commercialization. Here Li et al. incorporate crosslinkable molecules to form a crosslinked perovskite film and increase the device operational stability by 590 times to 400 h under standard Xenon lamp without filters.

Electrochemical conversion of CO₂ into value-added chemicals holds promise to enable the transition to carbon neutrality, but enhancing the selectivity toward a specific hydrocarbon product remains a challenging task. Now, the authors present a Cu–polyamine hybrid catalyst that achieves Faradaic efficiency of 87% for ethylene and full-cell energy efficiency of 50%.