The response of different immune cell subsets to radiation therapy (RT) greatly influences treatment outcome. Here, the authors compare the effects of RT and Boron neutron capture therapy (BNCT) in preclinical mouse models of melanoma and colorectal cancer, and show that BNCT achieves tumor cell-selective killing while preserving immune cell functions, allowing sustained anti-tumor immunity and long-term memory.
- Qi Sun
- Yanping Zhao
- Zhibo Liu
