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Showing 1–50 of 2344 results

Advanced filters: Author: M C Stevens Clear advanced filters

Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening severe cutaneous drug reaction mediated by CD8⁺ T cells. Here the authors characterise the immune response in skin samples at the site of tissue damage from patients affected with SJS/TEN and compare this to healthy skin or blister fluid and find populations of CD8⁺ T cell clonotypes expressing cytotoxic mediator molecules.

Andrew Gibson
Ramesh Ram
Elizabeth J. Phillips
ResearchOpen Access08 Oct 2024
Nature Communications

Volume: 15, P: 1-16
Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications

Mayumi Ueta
Hiromi Nishigaki
Chie Sotozono
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-10
Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement

Mayumi Ueta
Nahoko Kaniwa
Shigeru Kinoshita
ResearchOpen Access30 Apr 2014
Scientific Reports

Volume: 4, P: 1-6
Association of Human Leukocyte Antigen Class 1 genes with Stevens Johnson Syndrome with severe ocular complications in an Indian population

Chitra Kannabiran
Mayumi Ueta
Shigeru Kinoshita
ResearchOpen Access21 Nov 2017
Scientific Reports

Volume: 7, P: 1-4
Association of HLA class I and II gene polymorphisms with acetaminophen-related Stevens–Johnson syndrome with severe ocular complications in Japanese individuals

Mayumi Ueta
Ryosuke Nakamura
Shigeru Kinoshita
ResearchOpen Access28 Oct 2019
Human Genome Variation

Volume: 6, P: 1-6
Predictive biomarkers for the progression of ocular complications in chronic Stevens-Johnson syndrome and toxic Eeidermal necrolysis

Yamato Yoshikawa
Mayumi Ueta
Chie Sotozono
ResearchOpen Access03 Nov 2020
Scientific Reports

Volume: 10, P: 1-6
HLA-A*02:06 and PTGER3 polymorphism exert additive effects in cold medicine-related Stevens–Johnson syndrome with severe ocular complications

Mayumi Ueta
Katsushi Tokunaga
Shigeru Kinoshita
ResearchOpen Access16 Jul 2015
Human Genome Variation

Volume: 2, P: 1-5
Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications

Mayumi Ueta
Chitra Kannabiran
Shigeru Kinoshita
ResearchOpen Access07 Aug 2014
Scientific Reports

Volume: 4, P: 1-4
ClpC1-targeting peptide natural products differentially dysregulate the proteome of Mycobacterium tuberculosis

In this work, the authors reveal that three non-ribosomal peptides targeting a common protein quality system differentially alter the Mycobacterium tuberculosis proteome, providing new insight into the molecular mechanisms behind their antimycobacterial activity.

Isabel K. Barter
Max J. Bedding
Richard J. Payne
ResearchOpen Access29 Jan 2026
Nature Communications

P: 1-17
Identification of HLA-A*02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing

Ken Nakatani
Mayumi Ueta
Katsushi Tokunaga
ResearchOpen Access07 Nov 2019
Scientific Reports

Volume: 9, P: 1-8
Mapping of susceptible variants for cold medicine-related Stevens–Johnson syndrome by whole-genome resequencing

Yosuke Kawai
Yuki Hitomi
Katsushi Tokunaga
ResearchOpen Access11 Feb 2021
npj Genomic Medicine

Volume: 6, P: 1-8
Regulation of gene expression by miRNA-455-3p, upregulated in the conjunctival epithelium of patients with Stevens–Johnson syndrome in the chronic stage

Mayumi Ueta
Hiromi Nishigaki
Shigeru Kinoshita
ResearchOpen Access14 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
The global extent of the grassland biome and implications for the terrestrial carbon sink

By combining satellite observations with ground-based data and expert validation, this analysis demonstrates considerable misestimation of grassland extent and thereby carbon stock estimates in previous global assessments based on remote sensing.

A. S. MacDougall
B. Vanzant
M. B. Siewert
Research27 Jan 2026
Nature Ecology & Evolution

P: 1-12
A marker for Stevens-Johnson syndrome …: ethnicity matters

C Lonjou
L Thomas
J-C Roujeau
Research17 Jan 2006
The Pharmacogenomics Journal

Volume: 6, P: 265-268
Genome-wide association study using the ethnicity-specific Japonica array: identification of new susceptibility loci for cold medicine-related Stevens–Johnson syndrome with severe ocular complications

Mayumi Ueta
Hiromi Sawai
Katsushi Tokunaga
ResearchOpen Access19 Jan 2017
Journal of Human Genetics

Volume: 62, P: 485-489
A whole-genome association study of major determinants for allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis in Japanese patients

M Tohkin
N Kaniwa
Z Ikezawa
Research13 Sept 2011
The Pharmacogenomics Journal

Volume: 13, P: 60-69
NATURAL SCIENCE IN HUNGARY IN THE LAST TEN YEARS

J. M. A.
News26 Sept 1878
Nature

Volume: 18, P: 582-583
Biological Action of ‘Mustard Gas’ Compounds: Mutagenic Activity of beta-Chloroalkyl Amines and Sulphides

CARL M. STEVENS
AUGUSTA MYLROIE
Research16 Dec 1950
Nature

Volume: 166, P: 1019
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs

Manuela Neuman
Radu Nanau
Paul Hwang
ResearchOpen Access30 Sept 2011
Nature Precedings

P: 1
Deglaciation of the Prudhoe Dome in northwestern Greenland in response to Holocene warming

The ~500-metre-thick Prudhoe Dome in northwestern Greenland completely deglaciated 7,000 years ago, highlighting the sensitivity of the ice sheet to mid-Holocene warming, according to luminescence and geochemical data from sub-ice sediments and ice cores.

Caleb K. Walcott-George
Nathan D. Brown
Joerg M. Schaefer
Research05 Jan 2026
Nature Geoscience

P: 1-6
Permafrost slows Arctic riverbank erosion

Analysis of the sub-seasonal patterns of river migration reveals that permafrost reduces erosion rates and suggests that full permafrost thaw may lead to a 30–100% increase in the migration rates of Arctic rivers.

Emily C. Geyman
Madison M. Douglas
Michael P. Lamb
Research09 Oct 2024
Nature

Volume: 634, P: 359-365
Ribonucleic Acids in Liver Cytoplasm

E. REID
BARBARA M. STEVENS
Research16 Aug 1958
Nature

Volume: 182, P: 441-444
Landscape effects on global soil pathogenic fungal diversity across spatial scales

How landscapes are arranged affects soil pathogenic fungi worldwide. The authors reveal the global pattern and pronounced scale-dependency of landscape complexity and land-cover quantity on soil pathogenic fungal diversity.

Yawen Lu
Nico Eisenhauer
Carlos A. Guerra
ResearchOpen Access09 Jan 2026
Nature Communications

Volume: 17, P: 1-15
Late-stage C–H functionalization of complex alkaloids and drug molecules via intermolecular rhodium-carbenoid insertion

The ability to functionalize a C–H bond is useful in complex organic syntheses, but the scope of this approach is sometimes limited by its sensitivity to basic amines. Here, the authors achieve functionalization of amine-containing natural products by site-selective rhodium-carbene-mediated C–H insertion.

Jing He
Lawrence G. Hamann
Rohan E. J. Beckwith
Research12 Jan 2015
Nature Communications

Volume: 6, P: 1-9
Biological Action of ‘Mustard Gas’ Compounds: Mutagenic Activity of some ‘Mustard Gas’ Compounds

K. A. JENSEN
INGER KIRK
M. WESTERGAARD
Research16 Dec 1950
Nature

Volume: 166, P: 1020-1021
Emergence of Potato Blight, 1843–46

P. M. AUSTIN BOURKE
Research22 Aug 1964
Nature

Volume: 203, P: 805-808
Electrophoretic and Immunological Studies on Structural Sub-Units of Human Ceruloplasm

M. D. POULIK
Research02 Jun 1962
Nature

Volume: 194, P: 842-844
A calcium-based plasticity model for predicting long-term potentiation and depression in the neocortex

The study of learning algorithms in the neocortex requires comprehensive knowledge of synaptic plasticity between its diverse cell types, which is currently lacking. Chindemi et al. describe a modeling approach to fill these gaps in experimental literature, and predict the features of synaptic plasticity in vivo.

Giuseppe Chindemi
Marwan Abdellah
Eilif B. Muller
ResearchOpen Access01 Jun 2022
Nature Communications

Volume: 13, P: 1-19
Exchange Reactions in the Entry of Cations into Plant Tissues

R. SCOTT RUSSELL
M. J. AYLAND
Research29 Jan 1955
Nature

Volume: 175, P: 204-205
Chemistry, Toxicology, Pharmacology and Microbiology of a new Acid-Stable Penicillin, Resistant to Penicillinase (BRL.1621)

J. H. C. NAYLER
A. A. W. LONG
R. SUTHERLAND
Research29 Sept 1962
Nature

Volume: 195, P: 1264-1267
Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

Here authors show loss of AKAP11, a strong genetic risk factor for bipolar disorder and schizophrenia, disrupts PKA proteostasis and signaling, leading to widespread transcriptomic alterations across the brain, particularly in striatal neurons, as well as altered behavior.

Bryan J. Song
Yang Ge
Morgan Sheng
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-25
Multiplex serology reveals age-specific immunodynamics of respiratory pathogens in the wake of the COVID-19 pandemic

Non-pharmaceutical interventions for COVID-19 also reduced circulation of endemic viruses which may have led to immune waning. Here, the authors use multiplex serology data from King County, Washington, US to characterise age-specific changes in antibody levels to a range of endemic viruses during the COVID-19 pandemic.

Samantha J. Bents
Emily T. Martin
Cécile Viboud
ResearchOpen Access10 Dec 2025
Nature Communications

Volume: 16, P: 1-12
Penicillin-Like Substances in Preparations of 6-Aminopenicillanic Acid

F. R. BATCHELOR
M. COLE
G. N. ROLINSON
Research08 Sept 1962
Nature

Volume: 195, P: 954-955
Impacts of an industrial deep-sea mining trial on macrofaunal biodiversity

A species-level dataset of sediment-dwelling macrofauna, sampled 2 years before and 2 months after a test of a commercial deep-sea mining machine, reveals losses of macrofaunal density and species richness within the machine’s tracks and community-level effects in both the tracks and an area impacted by sediment plumes.

Eva C. D. Stewart
Helena Wiklund
Adrian G. Glover
ResearchOpen Access05 Dec 2025
Nature Ecology & Evolution

P: 1-12
Ovarian teratomas in mice are derived from oocytes that have completed the first meiotic division

JOHN J. EPPIG
LESLIE P. KOZAK
LEROY C. STEVENS
Research01 Oct 1977
Nature

Volume: 269, P: 517-518
Carbon dynamics of a controlled peatland rewetting experiment in the Norwegian boreal zone

Michael A. H. Bekken
Astrid Vatne
Norbert Pirk
ResearchOpen Access17 Dec 2025
Scientific Reports

Volume: 16, P: 1-16
Pre-existing cross-reactive immunity to highly pathogenic avian influenza 2.3.4.4b A(H5N1) virus in the United States

Highly pathogenic avian influenza A H5N1 clade 2.3.4.4b virus has caused outbreaks in dairy cattle and cases in humans in the United States. Here, the authors assess levels of pre-existing cross-reactive antibodies to the epidemic virus strain in human serum samples collected in the United States.

Zhu-Nan Li
Feng Liu
Min Z. Levine
ResearchOpen Access08 Dec 2025
Nature Communications

Volume: 16, P: 1-14
Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

Structurally resolving glycans remains a challenge. Here, the authors analyse influenza H3 hemagglutinin glycan evolution to show that over five decades of glycan incorporation highly impact structural stability and epitope accessibility, particularly in the head domain, providing key insights for vaccine design.

Rebeca de Paiva Froes Rocha
Ilhan Tomris
Andrew B. Ward
ResearchOpen Access11 Dec 2025
Nature Communications

Volume: 16, P: 1-14
Template Requirement in the Primary Antibody Response

K. M. STEVENS
Research07 Dec 1963
Nature

Volume: 200, P: 1017
Bone Turnover Model based on a Continuously Expanding Exchangeable Calcium Pool

L. BURKINSHAW
D. H. MARSHALL
M. M. YOUNG
Research12 Apr 1969
Nature

Volume: 222, P: 146-148
Valency Changes of Molybdenum During the Enzymatic Reduction of Nitrate in Neurospora

D. J. D. NICHOLAS
H. M. STEVENS
Research03 Dec 1955
Nature

Volume: 176, P: 1066-1067
Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin

V. Jevtović-Todorović
S. M. Todorovć
J. W. Olney
Research01 Apr 1998
Nature Medicine

Volume: 4, P: 460-463
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

Pathogenic variants in UNC13A underlie a novel neurodevelopmental syndrome, with three subtypes defined by distinct genotypes with varying clinical and functional impacts characterized in cellular and animal models.

Reza Asadollahi
Aisha Ahmad
Noa Lipstein
ResearchOpen Access22 Oct 2025
Nature Genetics

Volume: 57, P: 2691-2704
‘Hormonal’ risk factors, ‘breast tissue age’ and the age-incidence of breast cancer

M. C. Pike
M. D. Krailo
D. G. Hoel
Research30 Jun 1983
Nature

Volume: 303, P: 767-770
Intracellular Postsynaptic Potentials and Location of Synapses in Pyramidal Cells of the Cat Olfactory Cortex

M. A. BIEDENBACH
CHARLES F. STEVENS
Research22 Oct 1966
Nature

Volume: 212, P: 361-362
Presynaptic mechanism for long-term potentiation in the hippocampus

John M. Bekkers
Charles F. Stevens
Research23 Aug 1990
Nature

Volume: 346, P: 724-729
Concentration Effects in Chromatographic Analysis

I. D. RATTEE
D. M. LEWIS
C. B. STEVENS
Research16 Oct 1965
Nature

Volume: 208, P: 269-271
Molecular and electronic structure of terminal and alkali metal-capped uranium(V) nitride complexes

Actinide electronic structure determination is fundamentally challenging. Here, the authors assemble a family of uranium(V)-nitrides and quantify the electronic structure of the molecules, defining the relative importance of spin orbit coupling and crystal field interactions.

David M. King
Peter A. Cleaves
Stephen T. Liddle
ResearchOpen Access20 Dec 2016
Nature Communications

Volume: 7, P: 1-14
Projecting the morbidity burden of mental and behavioral disorders associated with increasing humid heat in Shanghai

This research quantifies hospital admissions in Shanghai for mental and behavioral disorders linked to humid heat, projecting a 68.2% increase by the 2090s under high greenhouse gas emissions and emphasizing the importance of mitigation strategies to reduce future morbidity burdens.

Chen Liang
Jiacan Yuan
Ragnhild Brandlistuen
Research02 Dec 2025
Nature Mental Health

Volume: 3, P: 1532-1544
Developing the ¹³⁴Ce and ¹³⁴La pair as companion positron emission tomography diagnostic isotopes for ²²⁵Ac and ²²⁷Th radiotherapeutics

¹³⁴Ce and ¹³⁴La have great potential as companion diagnostic isotopes for radiotherapeutics labelled with α-emitting ²²⁵Ac and ²²⁷Th. Now, by controlling the Ce^III/Ce^IV redox couple, the large-scale production, purification and characterization of ¹³⁴Ce- and ¹³⁴La-based radiolabels has been achieved and their use for in vivo positron emission tomography is demonstrated.

Tyler A. Bailey
Veronika Mocko
Rebecca J. Abergel
Research14 Dec 2020
Nature Chemistry

Volume: 13, P: 284-289

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