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Here, Ni-anchored Ru/RuO₂ heterostructure nanosheets serve as CO-tolerant hydrogen oxidation catalyst delivering a peak power density of 1.76 W cm^-2, along with long-term stability in an alkaline exchange membrane fuel cell operating under H₂/Air conditions.

Creating renewable nitriles faces challenges like competitive adsorption and harsh conditions. Here a CoRu dual-atom catalyst enables efficient ammoxidation of aldehydes to nitriles under ambient conditions through synergistic adsorption.

Developing Ru-intermetallic catalysts for mild ammonia synthesis faces structural complexity. Here, machine learning identified Sc_1/8Nd_7/8Ru₂, optimizing Ru–N bonding and orbital hybridization, enhancing catalytic activity under mild conditions.

Electrochemical nitrate reduction reaction offers a sustainable and efficient pathway for ammonia synthesis. Here, the authors report a unique K+ ions repelling effect on electron-deficient Ru electrocatalyst to realize efficient nitrate conversion under ampere-level current density.

Designing efficient and stable electrocatalysts for water splitting is of great interest for H2 fuel production. Here, the authors present a Ru nanoparticle catalyst on TiN, achieving 20 A mg−1 Ru at 63 mV in alkaline conditions, and operating at 5 A cm−2 for over 1000 hours in an anion exchange membrane electrolyzer.

There is an increasing interest in understanding how defect chemistry can alter material reactivity. Here, authors tune the electronic structure of RuO₂ by introducing W and Er dopants that boost acidic oxygen evolution performances by limiting oxygen vacancy formation during catalysis.

A short peptide derived from a commensal-fungal-secreted protein promotes repair in models of colon epithelial damage when delivered directly or via probiotic microbes.

Electrochemical water splitting is promising for sustainable energy, but relies on development of electrocatalysts for hydrogen evolution. Here the authors report nitrogen- and ruthenium-codoped carbon nanowires in which ruthenium atoms in a carbon matrix drive electrocatalysis of hydrogen evolution

Controlling localization of multiple metal nanoparticles on a single support is at the cutting edge of designing innovatory cascade catalysts. Here, the authors report a multicompartmentalized mesoporous organosilica to spatially position different metal nanoparticles in intimate proximity for efficient sequential hydrogenation reactions.

Previous structural studies of T cell recognition of SARS-CoV-2 have been confined to spike epitopes. Here the authors assess T cell recognition of SARS-CoV-2 nucleocapsid epitopes, which are more conserved than spike epitopes, providing structural insights into recognition of two epitopes.

Wang et al. propose a 3D meta-holographic zoom micro-projector, integrating a high-resolution metasurface with a tailored liquid lens, resulting in a 3D zoom micro-projector of only 0.18 cm³, small enough to fit on a fingertip.

Achieving general, efficient, and para-selective C-H amination under mild conditions remains a significant challenge. Here the authors report a fluorosulfuryl imidazolium triflate-mediated para-selective C-H amination of N-arylhydroxylamines for the synthesis of 1,4-diaminoarenes or para-azidoanilides.

The presence of electrically active defects on the surface of the support has been shown to be effective for N₂ activation. Here the authors discover that electron-rich polyanionic NH²⁻ defect allows for efficient ammonia synthesis via multiple reaction pathway by incorporating various affordable transition metals.

Cobalt ions in different sublayers of the double-layered Ruddlesden–Popper perovskite Sr₃Co₂O₇ are found to develop inequivalent ionic displacements, geometrically generating a polar state while preserving metallic conductivity and exhibiting antiferromagnetism.

A large number of marketed drugs contains a chiral carboxylic acid scaffold. Here, the authors report the asymmetric hydrogenation of α,β-unsaturated carboxylic acids to α-chiral carboxylic acids using a cobalt catalyst bearing an electron-donating chiral diphosphine ligand.

The Macaque Biobank initiated by Zhang et al. provides a comprehensive genetic and phenotypic characterization of Chinese rhesus macaques (CRMs). This resource enhances our understanding of the genetic diversity of CRMs and holds potential for biomedical research.

Ammonia is synthesized using a dual-site approach, whereby nitrogen vacancies on LaN activate N₂, which then reacts with hydrogen atoms produced over the Ni metal to give ammonia.

Artificial assembly of small functional proteins provides effective strategies for downsizing RNA degraders. Here, authors develop STAR, a hypercompact RNA degrader with evolved toxin endoribonucleases and engineered Cas6- CBS system, enabling efficient degradation of cytoplasmic and nuclear RNAs.

Electrocatalytic nitrogen reduction is promising for ammonia production, but electrocatalysts are limited by low efficiency and high cost. Here, the authors report electron-deficient copper nanoparticles, induced by rectifying contact with polyimide, for selective reduction of nitrogen to ammonia.

SARM1 is a key player in axon degeneration. Here, the authors generate a nanobody, which specifically recognizes the NMN-bound state of SARM1 and helps resolve the SARM1 structure in an intermediate state of activation.

Although SARS-CoV2 epitope characterization has been the focus of extensive research, these efforts have largely focused on the spike protein. Here, the authors demonstrate that CD8⁺ T cell responses can be directed against a dominant nucleocapsid epitope and rely on a highly focused T cell receptor repertoire.

The authors present an exciting 3D meta-holography based on angular spectrum diffraction theory that significantly improves depth limits. The showcased amorphous silicon metasurface with independent polarization control herein achieves a 47.5x depth increase and 0.95 dm depth reconstructions for polarization-independent and different color 3D meta-hologram.

Lysosomal activation via the MDM2-P53-V-ATPase axis unveils a potent host-directed strategy for eradicating intracellular pathogens and potentiating conventional antimicrobial therapy.

The high cost and low efficiency of current deuteration methods hinder scalable deuteration of organic compounds. Here, the authors report an electrolyser using Pdδ + /NC cathode achieving the deuteration of aldehydes, ketones, imines, and alkenes under solvent-free conditions using pure D2O.

The authors report coexisting ferromagnetism, polar distortion and metallicity in quasi-two-dimensional Ca₃Co₃O₈, providing a platform to exploit magnetoelectric coupling in a metallic system.

Stabilizing the ferroelectric phase in HfO₂ is a critical challenge for its application in next-generation nanoelectronics. Here, through a combination of first-principles calculations and experimental results the authors identify a critical extra-hole concentration for the stabilisation of the ferroelectric phase in HfO₂ thin films.

One key challenge in water science is to create a universal model that can predict the arrangement of water/solid interfaces. Here, the authors use STM and noncontact-AFM to discover common water clusters during the initial growth on hydrophilic and hydrophobic close-packed metal surfaces.

Converting solar energy to hydrogen fuel requires light-absorbers that well-match the wavelengths of incoming sunlight. Here, authors prepare a broadband visible-light-absorbing molecular complex that efficiently produces hydrogen from water.

This study demonstrated that different types of HC-Pros from potyviruses exhibit varying capacities to inhibit HEN1. This results in distinct levels of autophagic AGO1 degradation, which in turn leads to differences in RNA silencing suppression efficiency.

Durable agonism of NPR1 achieved with a novel investigational monoclonal antibody could mirror the positive hemodynamic changes in blood pressure and heart failure identified in humans with lifelong exposure to NPR1 coding variants.

Stabilize the active metal single atoms under harsh conditions is critical for the development of single atom catalysts. Here the authors report a nanoporous crystal, 12CaO·7Al₂O₃, that can firmly stabilize Pt single atoms in its surface cavities for efficient catalytic hydrogenation of nitroarenes.

In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

Platinum nanoclusters comprising about ten atoms each made by reducing isolated platinum cations in CeO_x nests isolated on high-area silica are demonstrated. Two forms of platinum were reversibly interconverted by oxidation/reduction, remaining stably confined to the nests even under severe conditions, in H₂ at 600 °C and under atmospheric pressure.

The ubiquitin E3 ligase OsCIE1 acts as a brake to inhibit OsCERK1 during homeostasis; this brake is released after chitin stimulation.

The study by Fu and colleagues presents a ferritin-adaptor platform for vaccine development, featuring a rabies virus vaccine candidate that enhances antigen stability and provides potent, durable protection after a single-dose administration.

This study reports that incorporating non-polar nanodomains into antiferroelectrics greatly enhanced the energy density and efficiency.

Tetracoordinate boron species are common radical precursors in organic synthesis, but the boron species are discarded as by-products. Herein the authors report a strategy to incorporate both the alkyl moiety and boron species into the eventual products, yielding organoboron compounds.

Metabotropic glutamate receptors exist as both homo- and heterodimers. Here, the authors report the mGlu2-4 receptor structures in the inactive, intermediate and active states, and reveal the reason for the partial activity of the mono-liganded dimers.

The nature of metal–ligand interactions remains unclear in coordination chemistry. Hao et al. address this question using in situelectrochemically controlled atomic force microscopy, which can monitor and modulate the coordinative bonding in a transition metal complex at a molecular level.

Genetic mechanisms underlying fetal hemoglobin (HbF) regulation and switching are not fully understood. Here, the authors develop a single-cell genome editing functional assay to model how effects of mutation-harbouring functional elements contribute to HbF expression.

The extracellular domain of the cell wall protein LtaS is an insulin-binding protein and mediates insulin resistance during Staphylococcus aureus infection.