Screening methods to predict the development of type 1 diabetes (T1D) prior to pancreatic β-cell disruption are currently lacking. Here, the authors perform proteomics analysis of cord serum samples obtained from a Swedish birth cohort and identify an inflammatory signature predictive of disease development with good accuracy, suggesting that an inflammatory stage during pregnancy predisposes to T1D.
- Angelica P. Ahrens
- Raquel Dias
- Johnny Ludvigsson
