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Showing 1–50 of 2046 results

Advanced filters: Author: S. A. McDonald Clear advanced filters

Implementing the 2017 McDonald criteria for the diagnosis of multiple sclerosis

The latest revision of the McDonald criteria for the diagnosis of multiple sclerosis (MS), released in 2017, was designed to facilitate early diagnosis of MS. Here, a panel of world-renowned MS specialists share their personal experiences of the new criteria.

Frauke Zipp
Jiwon Oh
Emmanuelle Waubant
Reviews13 May 2019
Nature Reviews Neurology

Volume: 15, P: 441-445
A radiolabeled dendrimer non-invasively identifies and tracks innate immune cell activation in a mouse model of experimental autoimmune encephalomyelitis

Non-invasive strategies to detect and track activated myeloid cells will facilitate disease diagnosis and monitoring in patients affected by neuroinflammatory disorders. Here, the authors present 18F-FMD, a dendrimer-based PET tracer that detects and monitors activated myeloid cells at different stages (presymptomatic and symptomatic) of Experimental Autoimmune Encephalomyelitis (EAE) in mice and in response to disease-modifying therapies.

Renesmee C. Kuo
Mackenzie L. Carlson
Michelle L. James
ResearchOpen Access30 Jan 2026
Nature Communications

Volume: 17, P: 1-14
Silencing lipid catabolism determines longevity in response to fasting

The relative contribution of lipid catabolism on fasting-induced longevity was unknown. Authors showed lifespan extension from fasting depend on silencing lipid catabolism upon nutrient replenishment through phosphorylation of NHR-49 by KIN-19.

Lexus Tatge
Juhee Kim
Peter M. Douglas
ResearchOpen Access22 Jan 2026
Nature Communications

P: 1-22
X-Ray and Optical Observations of the Pulsar NP 0532 in the Crab Nebula

H. BRADT
S. RAPPAPORT
J. KRISTIAN
Research24 May 1969
Nature

Volume: 222, P: 728-730
Response to Correspondence from McDonald et al.

Raghu Pullakhandam
Santu Ghosh
Harshpal S. Sachdev
Correspondence19 May 2022
European Journal of Clinical Nutrition

Volume: 76, P: 1202-1203
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

Eric Van Buren
Yi Zhang
Xihong Lin
Research31 Dec 2025
Nature Methods

P: 1-12
Transforming jet flavour tagging at ATLAS

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

G. Aad
E. Aakvaag
L. Zwalinski
ResearchOpen Access14 Jan 2026
Nature Communications

Volume: 17, P: 1-22
Natural gene therapy and the Darwinian legacy

Hagop Youssoufian
News & Views01 Jul 1996
Nature Genetics

Volume: 13, P: 255-256
A flexible extension of the log-logistic model with diverse failure rate shapes and applications

Ahmed Z. Afify
Mohamed E. Mead
Enayat M. Abd Elrazik
ResearchOpen Access24 Jan 2026
Scientific Reports

Volume: 16, P: 1-44
Endogenous inhibitor of prostaglandin synthetase

S. A. Saeed
Wendy J. McDonald-Gibson
H. O. J. Collier
Research03 Nov 1977
Nature

Volume: 270, P: 32-36
Cinematographic Recording of the Velocity of Arterial Blood-Flow

J. M. POTTER
D. A. McDONALD
Research07 Oct 1950
Nature

Volume: 166, P: 596-597
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling

In this study, Yu et al. found that a positive feedback loop between oxidized phosphatidylcholine and IL-1β promotes chronic neurodegeneration in the central nervous system and could be a contributing mechanism to progressive multiple sclerosis.

Ruoqi Yu
Brian M. Lozinski
Yifei Dong
Research01 Dec 2025
Nature Neuroscience

Volume: 29, P: 67-80
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors

Here the authors show that tissue-resident memory and exhausted T cells in tumors are distinct populations that are shaped by relative presence or absence of TCR signals, suggesting that a tailored therapeutic strategy is needed to target each subset.

Thomas N. Burn
Jan Schröder
Laura K. Mackay
ResearchOpen Access29 Dec 2025
Nature Immunology

Volume: 27, P: 98-109
Evidence for a charge-shift electrochromic mechanism in a probe of membrane potential

L. M. Loew
S. Scully
A. S. Waggoner
Research11 Oct 1979
Nature

Volume: 281, P: 497-499
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

K. S. Lee
R. W. Tsien
Research28 Apr 1983
Nature

Volume: 302, P: 790-794
Biomechanical effects of insole material stiffness on the human foot: a finite element analysis

Renbiao Lin
Xu Tao
Wencui Li
ResearchOpen Access29 Dec 2025
Scientific Reports

Volume: 15, P: 1-10
Neutral mutation hypothesis test

THOMAS S. WHITTAM
MASATOSHI NEI
Research14 Nov 1991
Nature

Volume: 354, P: 115-116
Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Variants in the PSMC5 gene impair proteasome function and cellular homeostasis, altering brain development in children. This study reveals underlying molecular mechanisms contributing to this neurodevelopmental phenotype, and suggests therapeutic leads for neurodevelopmental proteasomopathies.

Sébastien Küry
Janelle E. Stanton
Elke Krüger
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-21
Crystal Structures of [(CO)₃OsO]₄ and [(C₂H₅)₃PtCl]₄ and a Discussion of Known and Possible Related Tetrameric Compounds

R. S. NYHOLM
M. R. TRUTER
C. W. BRADFORD
Research14 Nov 1970
Nature

Volume: 228, P: 648-651
A resource to empirically establish drug exposure records directly from untargeted metabolomics data

This work presents a unified MS/MS spectral library of drugs and metabolites integrated with standardized pharmacologic metadata, enabling scalable, individualized profiling of drug exposure and metabolism directly from untargeted metabolomics data.

Haoqi Nina Zhao
Kine Eide Kvitne
Pieter C. Dorrestein
ResearchOpen Access09 Dec 2025
Nature Communications

Volume: 16, P: 1-16
Proton Magnetic Resonance Studies of Human Lysozyme

JACK S. COHEN
Research05 Jul 1969
Nature

Volume: 223, P: 43-46
Testing a digital and interactive scale (the three circles) to assess emotion regulation

Dylan Moloney-Gibb
Chase S. Sherwell
James N. Kirby
ResearchOpen Access10 May 2025
Scientific Reports

Volume: 15, P: 1-14
Genomic divergence of leopards in the Cape Floristic Region of South Africa: potential drivers for local adaptation

Laura Tensen
Anubhab Khan
Kathryn S. Williams
ResearchOpen Access24 Jan 2026
Heredity

P: 1-13
Spatially-restricted inflammation-induced senescent-like glia in multiple sclerosis and patient-derived organoids

In multiple sclerosis, smoldering inflammation contributes to clinical progression. Using multi-omics data, here the authors link chronic inflammation to senescence-like processes and cellular network changes, suggesting a potential therapeutic target.

Francesca Fagiani
Edoardo Pedrini
Martina Absinta
ResearchOpen Access26 Sept 2025
Nature Communications

Volume: 16, P: 1-26
Infra-red Spectra of Diamond Coat

R. M. CHRENKO
R. S. MCDONALD
K. A. DARROW
Research04 Feb 1967
Nature

Volume: 213, P: 474-476
Evidence for the Keplerian orbit of a close companion around a giant star

How do low-mass binaries age? Astronomers have constrained a tight, circular orbit of a close-in companion around a dying giant star, raising new questions about how tidal forces shape binary orbits in the final phases of stellar evolution.

Mats Esseldeurs
Leen Decin
Ka Tat Wong
Research13 Nov 2025
Nature Astronomy

Volume: 10, P: 124-143
FABP7 is increased in progressive multiple sclerosis and induces a pro-inflammatory phenotype in monocytes through a glycolytic switch

While immune dysregulation is acknowledged as causal for multiple sclerosis (MS), how monocytes contribute to MS etiology is still unclear. Here the authors analyze peripheral blood and cerebrospinal fluid samples as well as brain MRI image data from MS patients to implicate FABP7 in alteration of monocyte glycolysis, and as a potential marker for MS progression.

Rohit Patel
Devin King
Tanuja Chitnis
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-18
Editorial Expression of Concern: Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer

Christine M. Lovly
Nerina T. McDonald
William Pao
Amendments and Corrections20 Nov 2025
Nature Medicine

Volume: 31, P: 4316
Large benefits of timely planting

Advancing wheat sowing dates has a large benefit to crop yields in the Eastern Ganges Plain of India. The contribution of better crop calendar management to yield gains should be studied more extensively around the world, especially in underperforming regions.

Beibei Liu
Yi Yang
News & Views21 Jul 2022
Nature Food

Volume: 3, P: 495-496
Randomized trial testing a self-guided digital mental health intervention teaching calming skills for Ukrainian children

Joshua S. Steinberg
Jingxuan Sun
John R. Weisz
ResearchOpen Access16 May 2025
npj Mental Health Research

Volume: 4, P: 1-14
Cosmic Rays and the Sunspot Cycle: Primary α-Particle Intensity at Sunspot Maximum

P. S. FREIER
E. P. NEY
P. H. FOWLER
Research10 May 1958
Nature

Volume: 181, P: 1319-1321
Application of the ant colony optimization algorithm for the construction of a short version of the German alcohol decisional balance scale

Anne Moehring
Christian Meyer
Andreas Staudt
ResearchOpen Access25 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Extended Quarantine for Rabies

G. S. TURNER
Research18 Oct 1969
Nature

Volume: 224, P: 246-247
Electrostatic interactions in the assembly of haemoglobin

H. Franklin Bunn
Melisenda J. McDonald
Research01 Dec 1983
Nature

Volume: 306, P: 498-500
Testing the cross-cultural measurement invariance of the Penn state worry questionnaire for children (PSWQ-C) across Poland and the United States of America

Elżbieta B. Talik
Manuel S. Sprung
Bruce F. Chorpita
ResearchOpen Access13 Jan 2026
Scientific Reports

Volume: 16, P: 1-9
Flow of Viscous Liquids in Branched Tubes: with Reference to the Hepatic Portal Vein

C. H. BARNETT
W. COCHRANE
Research21 Apr 1956
Nature

Volume: 177, P: 740-742
Factors Affecting the Incidence of Club Root Disease of Brassicæ

JOHN COLHOUN
Research05 Jan 1952
Nature

Volume: 169, P: 21-22
Forms of Inositol Hexaphosphate in Soils

D. J. COSGROVE
Research30 Jun 1962
Nature

Volume: 194, P: 1265-1266
Defibrotide for prophylaxis of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) in pediatric high-risk patients: consensus guidelines from the European Society for Blood and Marrow Transplantation (EBMT)

Selim Corbacioglu
Rajinder Bajwa
Krzysztof Kalwak
ResearchOpen Access13 Jan 2026
Bone Marrow Transplantation

P: 1-9
Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens

Synthetic lethality can be used to identify potential drug targets in cancer based on simultaneous inactivation of two genes through genetic aberrations and gene silencing. Here, the authors develop a statistical framework to identify synthetic lethal pairs from large scale perturbation screens across multiple cancer types.

Sumana Srivatsa
Hesam Montazeri
Niko Beerenwinkel
ResearchOpen Access14 Dec 2022
Nature Communications

Volume: 13, P: 1-15
Elimination of a Glow Discharge in an Induction-heated Vacuum Furnace

J. P. BURDEN
Research15 Oct 1960
Nature

Volume: 188, P: 221-222
Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

α/β-hydrolase domain-containing protein 11 (ABHD11) is a mitochondrial hydrolase, and its expression in CD4 + T-cells has been linked to remission status in rheumatoid arthritis. Here the authors report that pharmacological inhibition of ABHD11 modulates T-cell effector function via increased 24,25-epoxycholesterol biosynthesis and subsequent liver X receptor activation.

Benjamin J. Jenkins
Yasmin R. Jenkins
Nicholas Jones
ResearchOpen Access03 Nov 2025
Nature Communications

Volume: 16, P: 1-18
Early identification of individuals at risk for multiple sclerosis by quantification of EBNA-1_381-452-specific antibody titers

Multiple sclerosis (MS) is linked to immune responses triggered by Epstein-Barr virus (EBV). Here, the authors demonstrate that elevated EBNA-1-specific IgG antibody titers, detectable soon after EBV seroconversion, are associated with individual MS risk potentially serving as a prognostic biomarker.

Hannes Vietzen
Laura M. Kühner
Elisabeth Puchhammer-Stöckl
ResearchOpen Access14 Jul 2025
Nature Communications

Volume: 16, P: 1-11
Simplified MRI prediction of clinically definite multiple sclerosis: a stepping stone towards treatment criteria?

Charles RG Guttmann
Comments & Opinion22 Jan 2008
Nature Clinical Practice Neurology

Volume: 4, P: 136-137
Where do general anaesthetics act?

N. P. Franks
W. R. Lieb
Research27 Jul 1978
Nature

Volume: 274, P: 339-342
Protein and Ribonucleic Acid Synthesis after Exposure to Warmth

EUGENE JACKIM
HARRY S. MCDONALD
Research22 Oct 1966
Nature

Volume: 212, P: 406
MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis—clinical implementation in the diagnostic process

The use of MRI in patients with multiple sclerosis (MS) is commonplace in clinical settings. However, the precise implementation of MRI in the diagnosis of MS is highly variable, which is problematic in the context of the substantial technical advances of the past decade. In these Evidence-based Guidelines, members of the MAGNIMS study group present a standardized approach to the use of MRI in the diagnosis of MS.

Àlex Rovira
Mike P. Wattjes
Xavier Montalban
ReviewsOpen Access07 Jul 2015
Nature Reviews Neurology

Volume: 11, P: 471-482
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

Noncoding transcripts contribute to the adaptation of cellular processes to oxygen levels. Here the authors characterize a hypoxia responsive lncRNA lincNORS and show that it has a role in cellular sterol homeostasis.

Xue Wu
Cristina M. Niculite
Mircea Ivan
ResearchOpen Access21 Sept 2020
Nature Communications

Volume: 11, P: 1-17
Phytochemical profiling in vitro and in silico evaluation of antioxidant, antimicrobial, and insecticidal properties of Moroccan matricaria chamomilla essential oil

El-Mehdi El-Assri
Anouar Hmamou
Abdelhak Bouia
ResearchOpen Access05 Dec 2025
Scientific Reports

Volume: 15, P: 1-17
Structure of cyclo-Octatetraene

E. R. LIPPINCOTT
R. C. LORD
R. S. McDONALD
Research05 Aug 1950
Nature

Volume: 166, P: 227

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