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EuCo₂Al₉ is identified as a metallic spin supersolid with high thermal conductivity, exhibiting coexisting spin orders, strong quantum fluctuations and a giant magnetocaloric effect enabling efficient sub-Kelvin refrigeration.

The study identified macrophage-derived lactate as a driver of hypertrophic scar. Lactate influx via MCT1 triggers histone lactylation in fibroblasts to activate profibrotic genes.

The authors report diode-like resistance in a non-magnetic topological insulator in the quantum Hall regime.

Despite being essential to many applications in quantum science, entanglement can be easily disrupted by decoherence. A protocol based on repetitive quantum error correction now demonstrates enhanced coherence times of entangled logical qubits.

Distributed multiparameter quantum metrology allows to probe multiple spatially distributed parameters across networked quantum systems. Here, the authors demonstrate distributed multiparameter quantum metrology in a modular superconducting quantum processor network.

Quantum error mitigation refers to techniques that reduce, rather than correct, errors in quantum computing. Here the authors demonstrate zero-noise extrapolation applied to quantum error correction circuits on superconducting processors, effectively reducing logical errors and advancing early fault-tolerant quantum computing.

Enteroendocrine cells in the gut sense food to regulate feeding behavior. Here, the authors show in Drosophila L-glutamate reduces the frequency of calcium oscillations in enteroendocrine cells and decreases the release of NPF, thereby reducing the activation of a pair of anorexic enteric neurons.

The 1,2 migration reaction on tetracoordinate boron species have been well investigated but less work looked on 1,2-boryl radical shift for the construction of organoborons. Here, the authors demonstrate a visible-light-induced photoredox neutral decarboxylative radical cross-coupling reaction, which undergoes a radical 1,2-boron shift to give a translocated C-radical for further capture of versatile radical acceptors

A mechano-intelligent transmission mechanism based on the slipknot delivers precise force signals for clinical practice and robotic operations such as minimally invasive surgery and tendon-driven robotics.

Here, the authors perform a large scale profiling of human gut prophages, revealing prophage-encoded disease-specific gene shifts, and further showing that prophage-encoded gene depleted in IBD helps reduce gut inflammation via oligosaccharide synthesis.

Recently, a Luttinger liquid state was reported in a moiré superlattice of bilayer tungsten ditelluride at small twist angles and temperatures of a few kelvins. Here, the authors extend this result to millikelvin temperatures, supporting the existence of the 2D anisotropic Luttinger liquid as a stable ground state.

An enhanced superconducting pairing temperature (T_g) has only been observed in single-layer FeSe interfaced with TiO_x system. Here, the authors construct a new interface composed of single-layer FeSe interfaced with LaFeO₃ showing a highest T_g of 80 K among all-known interfacial superconductors.

Selective functionalization of aromatic compounds is important in synthetic chemistry. Here the authors report anN-heterocyclic carbene-catalysed approach for enantioselectively converting ortho-hydroxyaldehydes to cyclic products, via activation of both phenol and aldehyde groups.

Low-frequency quasiperiodic oscillations in X-ray data are thought to trace the accretion flow in X-ray binaries. Here, the detection of 200 keV oscillations probes the innermost regions of MAXI J1820+070, revealing the precession of a small-scale jet.

This paper proposes a knowledge-guided self-learning mixed platoon control strategy for the coexistence of autonomous and traditional vehicles. The framework provides a generalizable and scalable solution for the development and adoption of connected autonomous vehicle systems.

Heo, Xu et al. used comprehensive plasma proteomics to identify 416 plasma proteins (294 new) associated with Alzheimer’s disease and applied machine learning to select 7 proteins that were highly predictive of Alzheimer’s disease across multiple cohorts.

Using EMTracer, EndoMTracer, and MMTracer, this study shows that myofibroblasts in kidney fibrosis mainly originate from resident fibroblasts, not full or partial EMT, EndoMT, or MMT, guiding research toward fibroblast-targeted therapies.

Phellodendron amurense is a Tertiary relict species with significant ecological and medicinal value. Here, the authors report its genome assembly and reveal the involvement of CNMT gene family is berberine biosynthesis.

Age-related hearing loss (ARHL) is a prevalent and complex disorder in older adults. Guo et al. identify human antigen R as a regulator of ARHL in aged mice and demonstrate that cochlear human antigen R overexpression alleviates ARHL, highlighting it as a therapeutic target for the condition.

Wadsleyite and ringwoodite rather than dense hydrous magnesium silicates dominate water storage in the mantle transition zone, according to high-pressure and temperature experimental analysis.

Through multimodal analyses of human cardiac tissues across different ages, Fan, Zheng, Zhan, Xu, Liu and colleagues reveal that RNA-binding protein ARID5A drives inflammaging by stabilizing the MAVS mRNA and activating the NF-κB–TBK1 pathway, and show that inactivating myocardial ARID5A attenuates cardiac senescence and functional decline.

Due to their layered structure, and resulting weak interlayer exchange coupling, van der Waals materials can exhibit distinct behaviour depending on whether the spins are aligned in the plane, or perpendicular. Here, via magnetoresistance measurements, Zhu et al provide direct evidence of a magneto-band-structure effect due to the alignment of the spin in the van der Waals magnet, Cr₂Ge₂Te₆.

Optically active defects in hBN are promising for quantum sensing and information applications, however, coherent control of a single defect has not been achieved so far. By using an efficient method to produce arrays of defects in hBN, Guo et al. isolate a new carbon-related defect and show its coherent control.

This study demonstrates that simple alkali etching enables in-situ regeneration of oxygen vacancies on CuO, enhancing peroxymonosulfate activation for efficient pollutant degradation with a 42-fold increase and long-term stability.

In this study, the authors isolated and characterized neutralizing antibodies from vaccinated individuals with SARS-CoV-2 BA.1 breakthrough infection and show that elite antibodies derived from specific germlines provide potent pan-variant neutralization capacity and in vivo protection.

An optoelectronic device that converts light into a postsynaptic signal after two stages of cascaded potentiation can mimic the synaptic facilitation function of the human retina and could be used to create a curvy neuromorphic imager.

Electrocatalysis is a powerful tool in organic synthesis, but asymmetric strategies are still less developed. Now a cobalt/pyridoxal electrocatalytic system facilitates electrochemical single-electron transfer and asymmetric induction for the enantioselective generation of α-quaternary amino esters.

Coherence is widely seen as essential for quantum source quality. Here, authors demonstrate on-chip photon states with increased brightness and purity using incoherent light. It reveals the mechanism of pump coherence and lowers the barrier for the generation of high-quality quantum states.

A crystal with giant birefringence in the visible and infrared could benefit applications that rely on manipulating optical polarization.

The development of macrocyclic hosts with high-affinity 1:2 recognition capabilities is crucial for its applications. Here, the authors introduce enantiopure chiral macrocycles with remarkable 1:2 recognition properties in water comparable to those of cucurbit[8]uril.

Influenza virus ribonucleoprotein complexes (RNPs) are essential for replication and transcription. Here, authors solve the cryo-EM structure of influenza mini-vRNP to reveal detailed FluPol–NP–RNA coupling and suggest a conformational shift in RNPs during the viral life cycle.

CABLE harnesses cytoarchitectural information such as cell or nuclear shape to infer fiber tracts in the brain of, for example, marmosets, macaques or humans.

Homogeneous earth-abundant metal catalysis based on well-defined metal complexes is of interest for organic synthesis, but typically employs expensive catalysts, air sensitive or synthetically challenging chemicals. Here, the authors report an efficient and regio-selective catalytic system for hydroboration of vinylarenes and organic nitriles with HBPin, using commercially available CoI₂ and KO^tBu under ligand-free conditions.

Nonsense mutations in OTOF cause hereditary deafness. RESTART v3 achieves efficient, precise readthrough at Otof c.1315 C > T (p.R439*) sites, reinstating arginine to yield full-length, functional otoferlin, markedly restoring hearing in mice and showing strong promise for clinical translation.

Regulation of the electronic structure in aromatic systems has a significant influence on their chemical reactivity. Here, the authors employ single-molecule junctions to precisely tune the position of a hydrogen atom through the electric field.

Circularly polarised luminescence (CPL) is essential for asymmetric synthetic photochemistry. Here, the authors integrate white quantum dots with chiral nematic liquid crystal or liquid crystal polymer to achieve single-emitted tuneable full-colour or white CPL for enantioselective polymerization.

β-Hydrogen elimination is a fundamental reaction in palladium catalysis, however, the eliminated β-hydrogen is usually attached to a sp³-carbon. Here, the authors report a palladium-catalyzed cross-coupling reaction involving a β-vinylic hydrogen elimination from an allylic palladium intermediate.

CRISPR base editors directly modify the non-target strand (NTS). Here, authors reveal an activity by miniature Cas12f cytosine base editor (CBE) to also edit the TS, and next engineer a TS-preferential CBE. The work establishes a strand-selectable miniature CBE toolkit with therapeutic potential.

Infection with SARS-CoV-2 causes interstitial pneumonia and viral replication in the lungs of transgenic mice that express a human version of ACE2, confirming the pathogenicity of the virus in this model.

An iontronic tip-sensing guidewire measures haemodynamic and contact pressure in animal stenosis models and can be integrated with commercial workhorse guidewires.

Distributed quantum sensing typically requires shared reference frames to coordinate measurements. Here, authors develop a reversed-encoding protocol that circumvents this requirement, enabling Heisenberg-limited precision in quantum networks without frame alignment.

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.