Louis Miller (National Institute of Allergy and Infectious Diseases) and Stephen Hoffman (Naval Medical Research Institute) review progress toward developing malaria vaccines. They argue that multiple antigens from different stages may be needed to protect the diverse populations at risk, and that an optimal vaccine would induce immunity against all stages. Vaccines for African children, in whom the major mortality occurs, must induce immunity against asexual blood stages.
- Louis H. Miller
- Stephen L. Hoffman
