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Whilst superlattices containing thin films of 5d transition metal oxides are expected to yield strong interfacial coupling, only weak effects have been observed. Here, the authors report strong coupling between 3d SrMnO₃ and 5d SrIrO₃due to the interplay of strong Coulomb and spin orbit interactions.

A single-cell epigenomic atlas of human immune cells highlights cell-type-specific features associated with genetic or environmental exposures.

Guided by density functional theory, a commercially viable refractory alloy is developed, which exhibits excellent room-temperature ductility and strength, and high strength at elevated temperatures.

The classification of magnets now includes altermagnets which possess opposite-spin sublattices connected by rotation and share some features with ferro- and antiferromagnets. Here the authors report the anomalous Hall effect in Mn5Si3 and interpret the results in terms of a d-wave altermagnetic phase.

A study reports a dual quantum spin Hall insulator in monolayer TaIrTe₄, arising from the interplay of its single-particle topology and density-tuned electron correlations.

A new type of Hall effect—the layer Hall effect—is produced in a 2D antiferromagnet that does not exhibit any net magnetization.

Previous measurements of interferometers based on quantum Hall (QH) edge channels have suggested potential electron pairing effects. Here, the authors investigate the coupling between QH edge channels in graphene Aharonov-Bohm (AB) interferometers, proposing a possible single-particle explanation for the apparent interference phase jumps and AB frequency doubling.

Interferometers can probe the wave-nature and exchange statistics of indistinguishable particles. Quantum Hall interferometers from graphite-encapsulated graphene heterostructures now enable the observation of the Aharonov–Bohm effect and of robust fractional quantum Hall states.

In electrostatically-gapped bilayer graphene, topologically-protected states can emerge at naturally occurring stacking domain walls even in the absence of a magnetic field. Here, the authors describe the interplay between such domain wall states and quantum Hall edge transport within the eight-fold degenerate zeroth Landau level of suspended bilayer graphene.

Graphene systems have the potential to host Wigner crystal states at zero magnetic field. Here, the authors report transport signatures consistent with Wigner crystallization in AB-stacked bilayer graphene at both zero and finite magnetic fields.

A simple transport model infers a material’s electronic dimensionality from standard transport measurements, revealing temperature-, doping- and alloying-driven shifts between low-dimensional and 3D transport in SrTiO₃, Bi₂O₂Se and Pb_1-xSn_xTe.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

Not only the area of Néel skyrmions, but also their number and sign contribute to their Hall resistivity.

Liquid charge density wave order is thought to occur in many correlated electron systems but has not been observed experimentally. Now, a liquid-like electronic state is shown to emerge in a transition metal dichalcogenide on photoexcitation.

This study examines long-term changes in species richness across tropical forests in the Andes and Amazon. Hotter, drier and more seasonal forests in the eastern and southern Amazon are losing species, while Northern Andean forests are accumulating species, acting as a refuge for climate-displaced species.

A combination of photoemission and scanning tunnelling spectroscopy measurements provide compelling evidence that single layers of 1T'-WTe₂ are a class of quantum spin Hall insulator.

The authors study epitaxial thin films of the pyrochlore-sublattice compound LiTi2O4 by RIXS and ARPES. They observe cooperation between strong electron correlations and strong electron-phonon coupling, giving rise to a mobile polaronic ground state in which charge motion and lattice distortions are coupled.

Climate change can alter when and how animals grow, breed, and migrate, but it is unclear whether this allows populations to persist. This global study shows that shifts in seasonal timing are key to helping vertebrate species maintain population growth under global warming.

cellSTAAR advances noncoding rare variant association analysis by integrating single-cell genomics data.

The quantum Hall effect is realized in a two-dimensional quantum gas system consisting of one spatial dimension and one synthetic dimension encoded in the atomic spin. Measurements show distinct bulk properties rooted in the topological structure.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

TEAD transcription factors are critical effectors and druggable sites of the Hippo pathway in cancer, however, the development of small molecule inhibitors and degraders remains underexplored. Here, the authors identify and characterize bifunctional IAP-based degraders targeting TEAD1 via a lipid pocket and recruit different members of the inhibitor of apoptosis proteins (IAPs) family, offering a comprehensive toolkit for structural, biophysical and cellular profiling.

Here the authors show that transient cell cycle arrest reprograms CD8⁺ T cells into a highly energized state, increasing proliferation and antitumor activity and boosting efficacy of immunotherapies in cancer models.

Macroscopic magneto-transport measurements enable investigation of the transport properties of materials in the presence of magnetic fields, yet they do not allow access to atomic scale details. Here, the authors combine scanning tunneling potentiometry with magnetic fields to demonstrate nanoscale magneto-transport.

Bernal-stacked bilayer graphene (BLG) has been extensively studied due to its tunable band gap and emerging electronic properties, but its low-energy band structure remains debated. Here, the authors report magnetotransport measurements of Bernal BLG, showing evidence of four Dirac cones and electrically induced topological transitions.

The author demonstrates that laser-driven ultracold Fermi gases can exhibit color-orbit-like coupling with SU(3) symmetry. This leads to color-like oscillations and other quantum-chromodyamics-like phenomena in an atomic physics laboratory.

Here the authors show that tissue-resident memory and exhausted T cells in tumors are distinct populations that are shaped by relative presence or absence of TCR signals, suggesting that a tailored therapeutic strategy is needed to target each subset.

A polariton is a hybrid excitation resulting from strong light–matter coupling. The magneto-transport measurements have now revealed the crucial role played by its electronic component.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

DNA double-strand breaks endanger genome stability. Here, the authors present cryo-EM structures showing how Ku70/80 and DNA-PK bind DNA ends on nucleosomes, offering a mechanistic model for break recognition within chromatin.

This study associates p53 loss and brain metastasis in breast cancer. Mechanistically, p53-null tumors recruit astrocytes that provide substrates for enhanced fatty acid synthesis via upregulated SCD1 expression, representing a targetable axis in the disease.

Magnetic impurities break time reversal symmetry in topological insulators, but there has been disagreement between theory and experiment. Here, the authors study the response of topological states to magnetic dopants at the atomic level and show that, contrary to what generally believed, magnetic order and gapless states can coexist.

The two-dimensional atomic layers of black phosphorus may be exfoliated to create devices with desirable electronic transport properties. Here, the authors observe two-dimensional quantum transport in black phosphorus quantum wells, protected from oxidation by encapsulation in a polymer layer.

The emergence of a liquid-like electronic flow from ballistic flow in graphene is imaged, and an almost-ideal viscous hydrodynamic fluid of electrons exhibiting a parabolic Poiseuille flow profile is observed.

The authors study microstructured UTe₂ by high-field transport, focusing on the field-reinforced superconducting phase. They reveal a highly-directional vortex pinning force typical of quasi-2D superconductors, indicating a vortex lock-in state and consistent with a change of order parameter from the low-field superconducting phase.

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

The influence of magnetic fields on the current-driven motion of domain walls in nanowires with perpendicular anisotropy shows that two spin–orbit-derived mechanisms are responsible for their motion.

The electrical current-induced creation, motion, detection and deletion of skyrmions in ferrimagnetic multilayers can be used to mimic the behaviour of biological synapses, providing devices that could be used for neuromorphic computing tasks such as pattern recognition.

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

The impact of late Pleistocene climate change on ecosystems has been hard to assess. Here, the authors sequence ancient DNA from Hall’s Cave, Texas and find that both plant and vertebrate diversity decreased with cooling, and though plant diversity recovered with rewarming, megafauna went extinct.