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The coexistence of topological and superconducting states in a single layer of FeSe on a SrTiO₃ substrate is reported.

Origami-based soft robotic manipulators offer compactness, cost-effectiveness, and scalability, but challenges related to stiffness, precision, and dexterity remain. To address these issues, the authors introduce the Micro-X4, a 4-degree-of-freedom origami micromanipulator that is capable of achieving three-dimensional translational motion, along with rotation around the central axis of the moving platform.

Release of the Damage-Associated Molecular Pattern ATP determines the immunogenic features of apoptosis, but the regulatory mechanisms are unclear. Here, the authors describe a pathway that inhibits ATP emission from dying cells to prevent immunogenicity.

The authors report their observation of the fractional quantum anomalous Hall effect in rhombohedral hexalayer graphene/hBN moiré superlattice devices.

Mass spectral analysis is used to map the composition of materials and surfaces in numerous fields. Here, the authors report a mass spectral technique based on extreme ultraviolet laser ablation that allows three-dimensional imaging of chemical composition in addition to giving highly sensitive nanoscale resolution.

A scanning tunnelling microscopy study of monolayer FeSe on strontium titanate reveals that this intriguing system has a plain s-wave pairing symmetry.

The joint analysis of datasets from NOvA and T2K, the two currently operating long-baseline neutrino oscillation experiments, provides new constraints related to neutrino masses and fundamental symmetries.

A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics.

In 1972, Erich Clar envisioned Clar’s goblet, a polycyclic aromatic hydrocarbon featuring two unpaired electrons that are spin-paired. However, synthesizing it in a solution phase remains challenging. Now a derivative of Clar’s goblet has been prepared in solution, and spin entanglement at the molecular scale has been demonstrated experimentally.

Investigating the inner structure of baryons is important to further our understanding of the strong interaction. Here, the BESIII Collaboration extracts the absolute value of the ratio of the electric to magnetic form factors and its relative phase for e + e − → J/ψ → ΛΣ decays, enhancing the signal thanks to the vacuum polarisation effect at the J/ψ peak.

Results from the first experimental campaign of the Wendelstein 7-X stellarator demonstrate that its magnetic-field design grants good control of parasitic plasma currents, leading to long energy confinement times.

Silicon carbide is a polymorphic material with over 250 known crystal structures. Here the authors show that such polymorphism can be used as a degree of freedom for engineering optically addressable and coherently interacting spin states, including many with room-temperature quantum coherence.

SUANPAN: A programmable and reconfigurable photonic linear vector machine with extreme scalability formed by a series of emitter-detector pairs as the independent basic computing units and implemented through time-space encoding.

A genome-wide association study including over 76,000 individuals with schizophrenia and over 243,000 control individuals identifies common variant associations at 287 genomic loci, and further fine-mapping analyses highlight the importance of genes involved in synaptic processes.

Phase separation is essential for various physiological processes. Feng et al. propose PSMutPred, a machine learning approach to predict impacts of missense mutations on phase separation and aid in understanding the pathogenesis of disease variants.

Wafer-scale 3R-MoS₂ with high phase purity is achieved through a homoepitaxy strategy, which demonstrates ferroelectricity and holds promise for multifunctional integration.

Two types of amyloid-β protein (1–42) (Aβ₄₂) fibrils are known to form in the insoluble fraction of diseased human brains. Now, another type of Aβ₄₂ fibril (type III) has been identified in the soluble fraction of Alzheimer’s disease brain using cryo-electron microscopy. These studies also reveal differences in ligand–fibril interactions between fibril types.

Zong et al. reveal that genetic and pharmacologic inhibition of TRPM7 channel function prevents the activation of Ca²⁺–CaM–calcineurin–KLF4 signaling, the phenotypic switch of vascular smooth muscle cells and the formation of abdominal aortic aneurysms.

By using a resonant sensor to couple two radio-frequency parametric oscillators behaving as Ising spins, a passive wireless device can implement programmable temperature threshold sensing.

Catenanes can exhibit chirality even when their component rings are achiral. Here an isostructural desymmetrization strategy is developed, demonstrating that two achiral rings, each featuring two mirror planes and a two-fold axis of symmetry, can form a catenane with tuneable mechanical chirality.

A nanofluidic intracellular delivery (NanoFLUID) patch provides a versatile, biocompatible and efficient method for the targeted delivery of payloads to internal organs for therapeutic purposes and for biomolecular investigations.

Metal anode instability due to several intrinsic factors limits their widespread use in energy storage. Here, the authors report a 3D alloy anode via a universal alloy electrodeposition approach to overcome the anode instability issues and demonstrate a seawater-based aqueous battery.

Metal- and N-coordinated carbon materials are promising electrocatalysts, but improved activity and stability are desirable for fuel cell applications. Chang et al. address this by introducing F atoms into Pd/N–C catalysts, modifying the environment around the Pd and enhancing performance for ethanol oxidation and oxygen reduction.

Here, the authors design NaNbO₃ based ceramics with the aim of enabling a field-induced reversible phase transformation between the antiferroelectric and ferroelectric phases, which manifests itself in a well-defined double hysteresis loop in the P-E hysteresis curve.

Human RNA binding protein Musashi-1 binds various host transcripts as well as Zika virus RNA in neural progenitor cells. Here, Chen et al. characterise the interactions between Musashi-1 and its binding site using a combination of molecular and biophysical methods to shed light on its role in viral neurotropism.

In ultrathin BiFeO₃ films on LaAlO₃, compressive strain of the substrate induces a polar skyrmion lattice with nanometre periodicity.

In situ mechanical testing and simulations unveil a reversible shuffle twinning mechanism enabled by bond switching, which gives rise to anisotropic tensile superelasticity in GeSe ceramics.

A complete genome assembly of a crab-eating macaque, revealing 46% fewer segmental duplications and 3.83 times longer centromeres than those of humans, is presented, enhancing understanding of lineage-specific phenotypes, adaptation and primate evolution.

Mass detection of single biological molecules in real time by a nanoelectromechanical system (NEMS) is demonstrated for the first time, and this is used to perform first generation NEMS-based mass spectrometry. Precipitous frequency shifts, proportional to the mass of the molecules, are recorded in real time by the NEMS mass spectrometry system as protein molecules and nanoparticles adsorb, one-by-one, onto an ultrahigh frequency NEMS resonator.

Enhancing the intrinsic activity and space time yield of Cu based heterogeneous methanol synthesis catalysts is one of the major topics in CO₂ hydrogenation. Here the authors develop a highly active inverse catalyst composed of fine ZrO₂ islands dispersed on metallic Cu nanoparticles.

The first operation of the European X-ray free-electron laser facility accelerator based on superconducting technology is reported. The maximum electron energy is 17.5 GeV. A laser average power of 6 W is achieved at a photon energy of 9.3 keV.

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

An intelligent environment has been developed for testing the safety performance of autonomous vehicles and its effectiveness has been demonstrated for highway and urban test tracks in an augmented-reality environment.

Ultrathin films of gallium oxide with a dielectric constant of around 30 can be formed on the surface of molybdenum disulfide using a liquid metal-based approach and used as the gate insulator in transistors.

The neural circuits that transmit cool signals remain not fully understood. Here, authors identify a spinal circuit in mice that transmits cool sensations from the skin to the brain, revealing a dedicated neural pathway for detecting innocuous cool temperatures.

The collective-flow-assisted nuclear shape-imaging method images the nuclear global shape by colliding them at ultrarelativistic speeds and analysing the collective response of outgoing debris.

The CMS Collaboration reports the study of three simultaneous hard interactions between quarks and gluons in proton–proton collisions. This manifests through the concurrent production of three J/ψ mesons, which consist of a charm-quark–antiquark pair.

A miniaturized and low-power-consumption system is designed to allow the accurate sensing and wireless transmission of internal temperature and strain signals inside lithium-ion batteries with negligible influence on their performance, improving their safety.

Recently, superconductivity near 80 K was observed in La3Ni2O7 under high pressure, but the mechanism is debated. Here the authors report angle-resolved photoemission spectroscopy measurements under ambient pressure, revealing flat bands with strong electronic correlations that could be linked to superconductivity.

A trans-ancestry meta-analysis of GWAS of glycemic traits in up to 281,416 individuals identifies 99 novel loci, of which one quarter was found due to the multi-ancestry approach, which also improves fine-mapping of credible variant sets.

The m6A binding protein YTHDF1 is frequently upregulated in cancer. Here the authors report that USP5 deubiquitinates and stabilizes YTHDF1, associated with cancer growth and immune evasion, and that targeting USP5 potentiates response to anti-PD-L1 in preclinical models.

Early stellarator designs suffered from high particle losses, an issue that can be addressed by optimization of the coils. Here the authors measure the magnetic field lines in the Wendelstein 7-X stellarator, confirming that the complicated design of the superconducting coils has been realized successfully.

The interaction between antiferromagnetic magnons and electrons sits at the heart of many strongly correlated systems, however, investigation has been hampered by a lack of clear-cut examples. Here, Yu et al directly observe a kink in the dispersion, a result of renormalization due to the electron-antiferromagnetic magnon interaction.

SEAM is a platform for the analysis of high-resolution secondary ion mass spectrometry imaging that allows spatially resolved nuclear metabolomic profiling at the single-cell level.

The recently discovered charge density wave in ScV₆Sn₆ kagome metal is under intense debate. By using a combination of experimental and theoretical techniques, the authors point to the role of flat phonon mode softening and momentum-dependent electron-phonon coupling in the formation of the charge density wave.

With ultra-deep RNA sequencing, Zhang et al. report increased usage of alternative promoters driven by AR, FOXA1 and MYC during prostate cancer progression and suggest altered DNA methylation as a potential underlying mechanism.