Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by rapid motor neuron (MN) degeneration, with unclear causes in sporadic cases. Here, the authors showed that N6-methyladenosine (m6A) RNA modification drives ALS, and restoring it may protect MNs and lessen motor issues.
- Ya-Ping Yen
- Ting-Hsiang Lung
- Jun-An Chen
