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A particle rotating in a fluid generates vorticity around itself. Now the dynamics of a collective of such spinners suspended in a liquid is shown to display flocking and three-dimensional active chirality.

Liquid jet formation is critical across climatology, environmental science, and health, yet traditional models neglect real-world factors like surface particulates. Here, authors demonstrate that surface particulates drastically lower the energy threshold for jet formation and reveal five new jet modes governed by the interplay between particulate immersion time and bubble depth.

Glioblastoma—the deadliest form of brain cancer—alters the calvarial bone and its marrow components, pushing it toward producing more myeloid cells and contributing to an immunosuppressive environment.

Here the authors use a range of approaches to examine the interplay between genetic variants linked to risk for polygenic skin diseases and transcription factors (TFs) important for skin homeostasis. The findings implicate dysregulated binding of specific TF families in risk for diverse skin diseases.

A gene therapy method using AAV can help deliver HIV-fighting antibodies long-term, but the body often rejects them. Here the authors show that a short course of the drug rapamycin helps prevent host anti-drug antibody responses, showing successful antibody delivery in mice and monkeys.

Small cell lung cancer cells form functional synapses with glutamatergic neurons, receiving synaptic transmissions and deriving a proliferative advantage from these interactions.

The ocean carbon sink strengthened in previous warm El Niño years due to reduced CO₂ outgassing in the tropics. Here the authors show that the ocean carbon sink declined in 2023 despite record-high sea surface temperatures (SSTs), primarily due to SST-driven outgassing of CO₂ in the subtropics.

Chemical doping allows for boosting the conductivity in conjugated polymers but the relationship between doping and the polymers’ complex, multiscale morphology remains elusive. Here the authors report that supramolecular chirality, which up to now had not been considered a parameter relevant to doping, significantly boosts the underpinning redox reaction in conjugated polymer thin films.

Context counts, and not just for social and economic aspects of urban life. This study finds that, for 16 cities in the United Kingdom, the landcover of the rural surroundings is a better predictor of ticks and environmental Lyme disease hazard than the landcover within the cities themselves.

The morphological complexity that develops on suspended sediment surfaces due to microbial colonization substantially increases drag, according to high-resolution microscopic imaging and fluid dynamics simulations.

Genome-wide association meta-analyses of attention-deficit/hyperactivity disorder symptom measures and clinical diagnoses identify new risk loci, highlight putative effector genes and yield improved polygenic risk scores.

iSCALE leverages histology and spatial transcriptomics to infer gene expression at super resolution in large tissues.

Modelling the statistical and geometrical properties of particle trajectories in turbulent flows is key to many scientific and technological applications. Li and colleagues introduce a data-driven diffusion model that can generate high-Reynolds-number Lagrangian turbulence trajectories with statistical properties consistent with those of the training set and even generalize to rare, intense events unseen during training.

The wetting behaviour of drops attached to fibres is exploited in many applications including fog harvesting. The presence of a background air flow on fibre-attached drops on parallel fibres is now shown to lead to alignment, repulsion and coalescence processes.

Cavitation is the formation of vapour bubbles within a liquid and is undesirable in many industrial applications. Here Stiegeret al. show how the anisotropic fluids influence this process in a nematic liquid crystal and find that orientational ordering of molecules can tune the onset of cavitation.

Transonic buffet is a ubiquitous challenge in commercial aviation since it can result in catastrophic structural failure of the aircraft wings. Here, authors experimentally show that this critical aerodynamic phenomenon can be mitigated using a carefully designed porous trailing edge on the wing.

The first controlled human infection model of cutaneous leishmaniasis transmitted by sand flies enables assessment of immune responses and parasitism in infected participants that can inform future vaccine and therapeutic development.

Nonlinear inertial flows usually influence the motion of swimming organisms, but most studies focus on the tractable case of swimmers too small to feel such effects. A mechanistic principle now unifies the varied dynamics of macroscopic swimmers.

Exploring astrophysical turbulent effects in laboratory plasma is challenging due to high threshold values of relevant parameters, such as the magnetic Reynolds number. Here the authors demonstrate the turbulent dynamo effect at large magnetic Reynolds numbers in laser-generated magnetized plasma.

Ultrasound-driven microbubbles are promising candidates for drug delivery, but the mechanism of action is unclear. Now, single microbubbles induce drug uptake through cyclic microjets formed at mild ultrasound pressures via interfacial instability.

Sharks’ dorsal fins are thought to assist propulsion and turns while pectoral fins are thought to oppose sharks’ negative buoyancy. Here, Payne and colleagues show that hammerhead sharks use an exaggerated dorsal fin to generate lift by swimming on their side.

Particle bombardment is a widely used tool for plant genetic engineering, but its low efficiency has been a bottleneck since its commercialization. Here, the authors design a flow guiding barrel to modulate particle and gas flow dynamics inside the gene gun and show its ability to enhance plant transformation efficiency.

Terrestrial and planetary subaqueous and aeolian ripples and dunes can be compared in a unified framework, according to simulations with a hydrodynamic and sediment transport model.

Microbial production of succinic acid at an industrially relevant scale has been hindered by high downstream processing costs arising from neutral pH fermentation. Here, the authors report an end-to-end pipeline for succinic acid production at low pH using engineered acid-tolerant Issatchenkia orientalis strain.

The authors characterize SMCHD1 as a nuclear lamina-associated protein in human myoblasts where it serves as an anchor for heterochromatin. Loss of SMCHD1 leads to B-to-A compartment transitions and numerous changes in 3D chromatin organization.

Understanding liquid friction on solid surfaces is key for fluid transport, with recent findings highlighting the role of solid internal excitations. Authors use AFM to show that supercooled glycerol’s slip length on mica increases unexpectedly strongly with decreasing temperature. The observations suggest that resonating vibrations within surface play a key role in liquid friction, challenging existing models.

In this study, Willenbockel et al. trace circulating itaconate in vivo to gain insight into its fate and systemic metabolism.

The energy transfer rate from a two-dimensional subaerial landslide to the tsunami produced may be limited to a value of about 70 % in the far field, according to Navier-Stokes simulations.

Supersonic turbulence is relevant to astrophysical plasmas with their study mostly limited to numerical simulations. Here the authors demonstrate supersonic turbulence in collisional high Mach number plasma jets generated in laboratory by using high power lasers.

The rapid decay of Earth’s dipole magnetic field has recently captured the public imagination. Here, the authors present a southern hemisphere magnetic record from South African Iron Age sites using oriented samples in the floors and suggest that the anomalous field behaviour is not just a recent feature.

A challenge of magnetically-actuated devices is to obtain different behaviours from each component under the same driving field. Here the authors tune the dipolar interactions between rotors to obtain different rotational behaviours when actuated by a magnetic field leading to complex collective dynamics.

Dioxythiophene-based polymers effectively convert electric potential into optical readouts. Here, the authors used such polymers to optically record bioelectric signals with microvolt sensitivity and sub-millisecond temporal resolution, highlighting their potential in optical bioelectronics.

Studying chemosensory processing desires precise chemical cue presentation, behavioral response monitoring, and large-scale neuronal activity recording. Here, the authors report a fluidics-based toolkit for studying chemosensation in larval zebrafish, and used it to reveal the brainwide neural representations of cadaverine sensing and its binasal input-dependent behavioral avoidance.