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Showing 1–50 of 2390 results
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  • The quark structure of the f0(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f0(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

    • A. Hayrapetyan
    • A. Tumasyan
    • A. Zhokin
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

    • Daya Guo
    • Dejian Yang
    • Zhen Zhang
    ResearchOpen Access
    Nature
    Volume: 645, P: 633-638
  • Lipid nanoparticles (LNPs) are a versatile class of clinically approved drug delivery vehicles, particularly for nucleic acid cargoes, but they often suffer from instability issues. Here, the authors report that the room temperature stability of small interfering RNA LNPs formulated with unsaturated ionizable lipids can be improved by inclusion of mildly acidic, antioxidant-containing buffers.

    • Daniel A. Estabrook
    • Lihua Huang
    • Tingting Wang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15
  • Polygenic risk scores can help identify individuals at higher risk of type 2 diabetes. Here, the authors characterise a multi-ancestry score across nearly 900,000 people, showing that its predictive value depends on demographic and clinical context and extends to related traits and complications.

    • Boya Guo
    • Yanwei Cai
    • Burcu F. Darst
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • High-resolution geospatial mapping found that the annual incidence of cholera shifted from western to central and eastern Africa between 2011 and 2020, with the latter regions more likely to report cholera in 2022–2023, reflecting instability in cholera burden patterns that can impact progress in disease control.

    • Javier Perez-Saez
    • Qulu Zheng
    • Elizabeth C. Lee
    ResearchOpen Access
    Nature Medicine
    P: 1-8
  • Distinguishing glioblastoma and primary central nervous system lymphoma (PCNSL) remains challenging due to their overlapping pathology features. Here, the authors develop a computational tool, PICTURE, for differentiating similar pathological features enabling improved diagnosis of CNS tumours.

    • Junhan Zhao
    • Shih-Yen Lin
    • Kun-Hsing Yu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • Federated learning (FL) algorithms have emerged as a promising solution to train models for healthcare imaging across institutions while preserving privacy. Here, the authors describe the Federated Tumor Segmentation (FeTS) challenge for the decentralised benchmarking of FL algorithms and evaluation of Healthcare AI algorithm generalizability in real-world cancer imaging datasets.

    • Maximilian Zenk
    • Ujjwal Baid
    • Spyridon Bakas
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20
  • A general stereospecific glycosylation is developed that is applicable across a range of monosaccharides. A directing-group-on-leaving-group strategy allows mild donor activation and enables the complete inversion of anomeric configuration with excellent yields. This method can be applied in multistep oligosaccharide syntheses and automated glycan assembly.

    • Qing Zhang
    • Nils J. Flodén
    • Liming Zhang
    Research
    Nature Synthesis
    P: 1-7
  • The sub-arc mantle has remained persistently oxidized since ~0.8 billion years ago, unaffected by increasing atmospheric and oceanic oxygen, according to machine learning techniques that classified arc basalts and revealed stable V/Sc.

    • Chun-Tao Liu
    • Chen-Yang Ye
    • J. ZhangZhou
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10
  • By controlling oxygen partial pressure, this study coerces Mn and Fe into divalent states, stabilizing seven new high-entropy rock salt oxides, and introduces oxygen chemical potential as a key design axis for predictive synthesis.

    • Saeed S. I. Almishal
    • Matthew Furst
    • Jon-Paul Maria
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-9
  • iExoKrasG12D are engineered exosomes for the delivery of siRNA targeting KRASG12D. Here the authors describe the results of a phase I trial of iExoKrasG12D in patients with metastatic pancreatic cancer, reporting safety and clinical activity, as well as immunological correlates informing on tumor immune microenvironment reprograming and future combination with immune checkpoint inhibitors.’

    • Valerie S. Kalluri
    • Brandon G. Smaglo
    • Raghu Kalluri
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • Here the authors use a range of approaches to examine the interplay between genetic variants linked to risk for polygenic skin diseases and transcription factors (TFs) important for skin homeostasis. The findings implicate dysregulated binding of specific TF families in risk for diverse skin diseases.

    • Douglas F. Porter
    • Robin M. Meyers
    • Paul A. Khavari
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-28
  • Finite momentum superconducting pairing refers to a class of unconventional superconducting states where Cooper pairs acquire a non-zero momentum. Here the authors report a new superconducting state in bulk 4Hb-TaS₂, where magnetic fields induce finite momentum pairing via magnetoelectric coupling.

    • F. Z. Yang
    • H. D. Zhang
    • H. Miao
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-9
  • Trained and validated on multimodal data from 14.5 million images from multicountry datasets, a foundation model is shown to increase diagnostic and referral accuracy of clinicians when used as an assistant in a trial involving 16 ophthalmologists and 668 patients.

    • Yilan Wu
    • Bo Qian
    • Bin Sheng
    Research
    Nature Medicine
    P: 1-10
  • In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

    • Erin M. Buchanan
    • Kelly Cuccolo
    • Savannah C. Lewis
    Research
    Nature Human Behaviour
    P: 1-20
  • The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task in mice.

    • Leenoy Meshulam
    • Dora Angelaki
    • Ilana B. Witten
    ResearchOpen Access
    Nature
    Volume: 645, P: 177-191
  • PandemicLLM adapts the large language model to predict disease trends by converting diverse disease-relevant data into text. It responds to new variants in real time, offering robust, interpretable forecasts for effective public health responses.

    • Hongru Du
    • Yang Zhao
    • Hao ‘Frank’ Yang
    Research
    Nature Computational Science
    Volume: 5, P: 467-480
  • Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

    • B. Kool
    • K. Verhaegh
    • V. Zamkovska
    ResearchOpen Access
    Nature Energy
    Volume: 10, P: 1116-1131
  • The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

    • R. Aaij
    • A. S. W. Abdelmotteleb
    • G. Zunica
    ResearchOpen Access
    Nature
    Volume: 643, P: 1223-1228
  • Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s  = 13 TeV and an integrated luminosity of 140 fb−1.

    • G. Aad
    • B. Abbott
    • L. Zwalinski
    ResearchOpen Access
    Nature
    Volume: 633, P: 542-547
  • Probing spectral properties of complex quantum many-body systems is challenging with existing theoretical and experimental techniques. Here, the authors introduce quantum simulations as a potential alternative to scattering spectroscopy for estimating the spectral features of many-body systems.

    • Jinzhao Sun
    • Lucia Vilchez-Estevez
    • M. S. Kim
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13
  • Direct human impact on land disturbances in the USA is declining, while less controllable, undirected wild disturbances are increasing, according to a long-term record of high-resolution satellite imagery.

    • Shi Qiu
    • Zhe Zhu
    • Ramakrishna R. Nemani
    Research
    Nature Geoscience
    Volume: 18, P: 989-996
  • The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

    • Marek Cmero
    • Ke Yuan
    • Christian von Mering
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15
  • A modelling study based on satellite observations, machine learning and a chemical transport model quantifies the global and regional exposure to particulate-matter pollution and the human health impacts related to the 2023 Canadian wildfires.

    • Qiang Zhang
    • Yuexuanzi Wang
    • Kebin He
    ResearchOpen Access
    Nature
    Volume: 645, P: 672-678
  • An analysis of 18 metagenomic datasets of individuals with colorectal cancer, adenomas and healthy controls yields improved cancer prediction accuracy based solely on gut metagenomics, as well as the identification of new species associated with the development of cancer.

    • Gianmarco Piccinno
    • Kelsey N. Thompson
    • Nicola Segata
    ResearchOpen Access
    Nature Medicine
    Volume: 31, P: 2416-2429
  • Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

    • Shimin Shuai
    • Federico Abascal
    • Christian von Mering
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12
  • An analysis of data from the Sherlock-Lung study provides insight into the mutational processes that contribute to lung cancer in never smokers, and looks at the possible role of factors such as air pollution and passive smoking.

    • Marcos Díaz-Gay
    • Tongwu Zhang
    • Maria Teresa Landi
    Research
    Nature
    Volume: 644, P: 133-144
  • Primary angle-closure glaucoma is a leading cause of blindness. Here, the authors identify rare deleterious variants in UBOX5 as risk factors and implicate BIP ubiquitination as a potential disease mechanism.

    • Zheng Li
    • Wee Ling Chng
    • Chiea Chuen Khor
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13
  • Multisystem inflammatory syndrome in children (MIS-C) onsets in COVID-19 patients with manifestations similar to Kawasaki disease (KD). Here the author probe the peripheral blood transcriptome of MIS-C patients to find signatures related to natural killer (NK) cell activation and CD8+ T cell exhaustion that are shared with KD patients.

    • Noam D. Beckmann
    • Phillip H. Comella
    • Alexander W. Charney
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15
  • Theory predicts that phonons—quanta of lattice vibrations—can carry finite angular momentum and thus influence physical properties of materials. Now phonons with angular momentum have been seen in tellurium with a chiral crystal structure.

    • H. Zhang
    • N. Peshcherenko
    • H. Miao
    Research
    Nature Physics
    Volume: 21, P: 1387-1391
  • Identifying genes involved in MYC-driven lymphoma reveals therapeutic vulnerabilities. Here, the authors show by using CRISPR knockout screens in primary cells in vivo that the GATOR1 complex suppresses MYC-driven lymphomagenesis, and that GATOR1-deficient lymphomas are sensitive to mTOR inhibitors.

    • Margaret A. Potts
    • Shinsuke Mizutani
    • Marco J. Herold
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14
  • Assessing brain aging heterogeneity in a cohort of 49,482 individuals from 11 studies, a generative model identifies five dominant patterns of brain atrophy, with specific associations with biomedical, lifestyle and genetic factors.

    • Zhijian Yang
    • Junhao Wen
    • Christos Davatzikos
    Research
    Nature Medicine
    Volume: 30, P: 3015-3026
  • While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

    • M. Ablikim
    • M. N. Achasov
    • J. Zu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-9
  • Nickelate superconductors attract enormous attention in the field of high-temperature superconductivity. Here the authors report observation of perfect diamagnetism and interfacial effect on the electronic structures in infinite layer Nd0.8Sr0.2NiO2 superconductors.

    • S. W. Zeng
    • X. M. Yin
    • A. Ariando
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-6
  • Cationic polymers conventionally kill bacteria via physical membrane disruptions. Here, the authors report the development of carbon acid cationic polymers that show potent activity against multidrug-resistant strains in murine infection models and prevent bovine mastitis, and present evidence that these polymers translocate across bacterial membrane aided by N-heterocyclic carbene.

    • Chong Hui Koh
    • Mallikharjuna Rao Lambu
    • Mary B. Chan-Park
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18