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In a hybrid superconductor–ferromagnet device, the dynamic stray fields of current-driven vortices unidirectionally excite coherent short-wavelength magnons.

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

The authors conducted prospective multimodal monitoring of simultaneous brain and heart function to define physiological changes during the human dying process leading to circulatory arrest.

The use of antimicrobial agents can exacerbate the proliferation of antimicrobial resistance genes, which can put public health at risk; evaluating this risk requires proper monitoring. An extensive investigation of Australian wastewater reveals a distinct correlation between the type of antimicrobial used and the socioeconomic status of the population.

Particles produced by intense biomass burning can be transported, potentially by deep convection, in large numbers to the lower stratosphere, changing the stratospheric aerosol layer’s chemical and radiative properties, according to in situ measurements during an active fire season.

Hydrogen peroxide is a signaling molecule that can also cause damage if its levels are too high. Here, the authors report HyPerFLEX, a fluorescent sensor with tenable colors, to track very low peroxide levels in cellular organelles, even in low-oxygen or highly oxidizing environments.

Genomic sequencing of the thermotolerant coral species Oculina patagonica, single-cell transcriptomic analyses of symbiotic and non-symbiotic specimens and comparisons with obligate symbiotic coral species reveal adaptations that provide resilience to coral bleaching.

Ambient electromagnetic energy is ubiquitous, but it is a challenge to harvest this energy. Here the authors designed a dielectric polarization enabled textile which can harvest electromagnetic energy.

Distal mutations, though far from the active site, enhance Kemp eliminase catalysis by tuning conformational dynamics that facilitate substrate binding and product release, thereby promoting the full catalytic cycle.

The neural dynamics that optimize coordination of sensorimotor behaviour are not fully understood. Here authors show that the cerebellum receives a copy of the motor commands from the cerebrum during movement preparation, likely to generate motor predictions. During the execution, the cerebellum sends feedback to correct the motor cortical activity.

The analysis of radial velocity variations of O-type stars in the Small Magellanic Cloud reveals a large fraction of close binaries, suggesting that binary physics also plays a prominent role in the low-metallicity environment of the distant Universe.

The XRISM Resolve spectrum of the galactic neutron star X-ray binary, GX 13+1, reveals one of the densest winds ever seen in absorption lines.

Lai et al. show a function of astrocytic Ca²⁺ in preventing synaptic depotentiation by reducing repetitive dendritic activity in the motor cortex during motor training, thereby contributing to learning-dependent neuronal circuit modification.

New printing techniques demand methods capable of spreading uniform liquid films efficiently across surfaces. McHale et al.show that applying external electric fields to non-charged liquids can achieve this goal without complicated surface modification or adding surfactants in the liquids.

Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.

STING is a promising drug target, but selective activation is necessary for safety and efficacy. Researchers have developed a two-component prodrug system for potent pharmacological activation of STING that offers excellent tumour targeting.

A significant challenge in modern drug development is the comprehensive profiling of covalent inhibitors. Here, the authors develop COOKIE-Pro, an unbiased method for quantifying the binding kinetics of irreversible covalent inhibitors on a proteome-wide scale.

Using a trapped-ion quantum simulator of up to 50 spins, researchers explore new universal scaling laws in non-equilibrium dynamics, revealing unique critical behaviors following a sequence of quenches in a long-range 1D Ising model.

The electronic ground state of a correlated oxide interface is reversibly switched by light. Stemming from interfacial reconstructions, electrostatic confinement and photodoping, this effect opens a path towards engineering the optical response of oxides.

The Einstein Probe has discovered a fast X-ray transient, EP240414a, associated with a broad-lined type Ic supernova. Its unusually soft spectrum and weak jet add to the diversity of stellar deaths and suggest a previously unknown Wolf–Rayet star explosion mechanism.

A terahertz field exceeding 1 V nm⁻¹ induced a structural phase transition in the top atomic layer of a bulk WTe₂ crystal. Differential imaging revealed a surface shift of 7 ± 3 pm and an electronic signature consistent with a topological phase transition.

In vivo loss-of-function CRISPR screens were performed to identify genes influencing CAR T cell persistence and function in human multiple myeloma, highlighting CDKN1B as a promising target.

Comparison of the carbon balance during 2010–2018 with 2019 and 2020 shows that a decline in law enforcement may have led to an increase in Amazon forest carbon emissions.

This meta-analysis assesses the rates and drivers of greenhouse gas emissions from flowing and standing (sub)tropical inland waters, finding that emissions are lower than previous estimates. Considerable spatial variation in fluxes arises mainly from differences in hydroclimate, geomorphology, land cover and human disturbance.

Mellor et al. report that deficiency of GABARAPL1, an ATG8-specific linking protein, impairs diastolic function in diabetic mice. This effect can be reversed by gene delivery of the gene encoding GABARAPL1 in diabetic mice and a human organoid model of type 2 diabetes.

Military personnel face increased exposure to pandemic-related stressors, yet their mental health impacts remain underexplored. Here, the authors analyze data from the STARRS Longitudinal Study, revealing significant increases in mental health issues among soldiers during COVID-19, particularly among vulnerable groups, underscoring the need for targeted support during pandemics.

Coastal settlement retreat reflects human behavioural adaptation to increasing coastal climate hazards. Using night-time light data over 1992–2019, this study finds that over half of global coastal settlements have retreated, driven by insufficient infrastructure protection and adaptive capacity.

Measuring selection and dominance in fitness of the insecticide-resistant Ace alleles in Drosophila melanogaster, the authors show evidence for beneficial reversal of dominance, a mechanism that can stabilize large-effect polymorphisms in nature.

Brain age gaps (BAGs) highlight deviations from healthy brain aging, yet their biophysical underpinnings in aging and dementia are not well understood. Here, the authors use EEG connectivity and generative modeling across diverse populations to reveal that BAGs are influenced by geography, income, sex and education, with implications for understanding accelerated aging and dementia.

The zebra finch robust nucleus of the arcopallium (RA) directs singing by providing descending projections to brainstem motor neurons. The authors show that electrophysiological characteristics of RA neurons rely on resurgent Na+ currents that emerge early during song development only in males.

A strongly lensed galaxy at redshift z ≈ 6 is resolved into at least 15 star-forming clumps embedded in a rotating disk. Clump formation in this system, which is not predicted by cosmological zoom-in simulations, may be driven by disk instabilities with weak feedback, rather than past mergers.

Systematic characterization of Arabidopsis aminotransferase family enzymes uncovered many previously unrecognized activities and revealed their multi-substrate specificity, aspects that probably contribute to the robustness of the nitrogen metabolic network.

A unified framework is presented that integrates observed spatial patterns of individual trees in forests with ecological processes into a novel coexistence theory.

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

The authors combine tracking and body mass data from five migratory waterfowl species to understand their capacity to accelerate migration in response to earlier spring. They show considerable scope for faster migration by reducing the fuelling time before departure and subsequently on stopovers

Dielectric breakdown in Mott insulators induced by strong electric fields is thought to take place via a Zener mechanism. Guiot et al. show that the breakdown characteristics are instead similar to the avalanche breakdown in conventional semiconductors, although with much longer delay times.

Reliably probing rejuvenation and memory effects in spin glasses by means of simulations is difficult. Now, a state-of-the-art numerical study shows that at least three different length scales play a crucial role in aging dynamics of spin glasses.

Researchers observe directional strong coupling on the nanoscale between hyperbolic phonon polaritons and pentacene molecules.

Bennu comprises components of intra- and extra-Solar System origins. The parent bodies of Bennu, Ryugu and CI chondrites likely formed from a shared but heterogeneous reservoir in the outer parts of the solar protoplanetary disk.

The underlying physics of the strange metal phase observed in many strongly correlated materials is not well understood. Now, evidence emerges that antiferromagnetic spin fluctuations play an important role.

Observations of SN 2021yfj reveal that its progenitor is a massive star stripped down to its O/Si/S core, which remarkably continued to expel vast quantities of silicon-, sulfur-, and argon-rich material before the explosion, informing us that current theories for how stars evolve are too narrow.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

The authors present experimental evidence of three-dimensional superinsulation in a nanopatterned slab of NbTiN. In the electric Meissner state, they find polar nematic order arising from ferroelectric alignment of short electric strings excited by external electromagnetic fields.

The N-acyl-cyclolysine system regulates the expression of co-localized operons encoding diverse secreted molecules in Bacteroidota.