Clinical Sciences articles for France

Time frame: 1 May 2025 - 30 April 2026

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Count: 473

Article ‘Count’ for Clinical Sciences.

Journal Count Share
2 2.00
A multiscale finite element model of fluid-microstructure interactions in human intervertebral disc compression 1.00
Role of mechanical representativity in multiaxial and transverse mechanics of human annulus fibrosus: A microstructure-based biphasic finite element study 1.00
1 0.83
Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: A randomized, double-blind placebo-controlled study 0.83
1 1.00
Recovery after Low-Impact Laparoscopic Hysterectomy: A Randomized Controlled Clinical Trial 1.00
8 4.14
Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study 0.48
Study of Risk Assessment Scores as Surrogate Endpoints in Pulmonary Arterial Hypertension Trials 0.14
Plasma exchange for severe alveolar hemorrhage in ANCA-associated vasculitis: emulation of a target trial 0.98
Improving the Reporting of Trials Evaluating Organ Support Therapies Using Multistate Modeling 1.00
Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS) 0.05
Impact of Visitation Restrictions in ICU on Psychological Symptoms in Family Members: Experience of the COVID-19 Pandemic. 1.00
Physiological Consequences of Breathing Effort According to the Mode of Ventilation During Acute Hypoxemic Respiratory Failure. 0.29
Temporary Transvenous Diaphragm Neurostimulation for Weaning from Mechanical Ventilation (RESCUE-3). 0.19
3 0.25
Rapid Diagnosis of Bacteremia in Febrile Pediatric Oncology Patients via Host-Response Infrared Spectroscopy of Blood and Machine Learning 0.05
Seamless Tiling and Scalable Coherent Raman Spectroscopic Analysis Reveals Developmental Maturation of Lipids in the Mouse Brain 0.14
Augmentation of Infrared Microscopy of White Blood Cells and Medical Measures for Rapid and Accurate Diagnosis of Bacterial or Viral Infections in Febrile Pediatric Oncology Patients: An Expert System-Based Study 0.06
4 2.38
Severe post-operative bleeding after heart transplantation. 1.00
Relationship Between V̇A/Q̇ Mismatch and Capnogram Phase III Slope in Acute Bronchoconstriction and Its Modulation by Salbutamol Assessed by Synchrotron Imaging in Rabbit Lung. 0.29
Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain. 0.09
Early use of norepinephrine in high-risk patients undergoing major abdominal surgery: a randomized controlled trial. 1.00
2 1.07
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis. 0.07
Rituximab Versus Conventional Therapy for Remission Induction in Eosinophilic Granulomatosis With Polyangiitis : A Randomized Controlled Trial. 1.00
2 0.36
The Spectrum of Neurologic Phenotypes Associated With scpiNUS1/i/scp Pathogenic Variants: A Comprehensive Case Series 0.28
Biallelic Variants in the scpiDARS2/i/scp Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease 0.08
6 2.25
Hepatectomies under Hypothermic Perfusion of the Liver: Analysis of 110 Cases from a Single Center. 1.00
Two-stage Hepatectomy Versus Liver Transplantation for Patients with Marginally Resectable Extensive Bilobar Colorectal Liver Metastases. 0.83
Long-Term Outcomes of Patients Undergoing Two-Stage Hepatectomy For Extensive Colorectal Liver Metastasis Treated With Perioperative Hepatic Artery and Systemic Chemotherapy. 0.05
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.08
Perioperative Outcomes in Open Versus Minimally Invasive Gastrectomy For Gastric Cancer: A European Multicenter Study Based on the GASTRODATA Registry. 0.03
Novel Benchmark for Robotic Liver Resection - Bridging Tradition with Innovation. 0.27
18 4.93
Response of ultrasound-assessed synovitis to baricitinib, in monotherapy and combined with methotrexate, compared with etanercept in rheumatoid arthritis: a randomised, international, multicentre trial 0.08
Musculoskeletal ultrasound findings in people with asymptomatic hyperuricemia: baseline analysis from the Transitions in Gout Research (TIGER) study using the OMERACT gout ultrasound semiquantitative scoring system 0.04
Psoriatic arthritis monocyte DNA methylomes bridge joint and skin inflammatory pathways across rheumatoid arthritis and psoriasis 0.04
Risk score for early mortality to stratify for intensive SSc therapy in the EUSTAR network: the RESIST score 0.20
Prevalence and impact of suspected fibromyalgia on disease outcomes and treatment in axial spondyloarthritis: 10-year follow-up data from the DESIR cohort 0.80
A phase 2, randomised, placebo-controlled study of guselkumab in adults with new-onset or relapsing giant cell arteritis 0.07
The positive perspective paradigm: proposal of a model to mitigate the impact of chronic inflammatory arthritis through comprehensive and early intervention 0.14
The incidence of interstitial lung disease in patients with systemic sclerosis: rate, risk factors and prognostic implications in a EUSTAR cohort analysis (CP 133) 0.06
A genetic variant of BAFF is associated with the risk of lymphoma in Sjögren disease 0.80
Evaluation of the placebo and treatment effect overtime in randomised clinical trials evaluating the efficacy of biologics in axial spondyloarthritis: systematic review and meta-analysis 1.00
A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis 0.14
Final validation of the hierarchical framework for outcomes in axial spondyloarthritis: longitudinal determinants of health-related quality of life 0.38
Development and validation of a Disease Activity index for PSoriatic Arthritis based on 44 joints (DAPSA44) 0.14
Spatial mapping of rheumatoid arthritis synovial niches reveals a LYVE1+ macrophage network associated with response to therapy 0.73
Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland 0.05
Genome-wide association study in chondrocalcinosis reveals ENPP1 as a candidate therapeutic target in calcium pyrophosphate deposition disease 0.13
Remote monitoring or patient-initiated care in axial spondyloarthritis: a 3-armed randomised controlled noninferiority trial 0.07
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1 0.07
1 1.00
Shoulder rotators isokinetic profile according to instability and/or sport specificity: Implications for rehabilitation Shoulder rotators isokinetic profile 1.00
13 8.17
Machine Learning to Predict Remission Between Six and 24 Months in Rheumatoid Arthritis: Insights from the JAK‐pot Collaboration 0.02
18F‐Fluorodeoxyglucose Positron Emission Tomography Imaging Assessment within a Randomized Controlled Trial in Giant Cell Arteritis 0.08
Prognosis and Long‐Term Outcome of Stenotic Large Vessel Involvement in Giant Cell Arteritis 1.00
Prediction of Relapse and Glucocorticoid Dependence in Eosinophilic Granulomatosis With Polyangiitis: Findings From a Large European Cohort 0.40
In synergy with interferon‐gamma, interleukin‐17 activates vascular stromal cells towards a pro‐inflammatory profile in giant cell arteritis 1.00
Antineutrophil Cytoplasmic Antibody–Associated Vasculitides in Systemic Sclerosis: A Unique Clinical Overlap With Significant Implications for Treatment and Outcomes 1.00
Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis 0.96
Incidence of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis Treated With scpJAK/scp Inhibitors Compared With Biologic Disease‐Modifying Antirheumatic Drugs: Data From an International Collaboration of Registries 0.03
Spermidine reproduces the anti‐inflammatory effects of intermittent fasting and prevents urate and calcium pyrophosphate crystal‐induced inflammation 0.98
Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients 0.05
Monocyte‐derived macrophages‐synovial fibroblasts crosstalk unravels oncostatin signaling network as a driver of synovitis in osteoarthritis 1.00
A tolerogenic plasmid inhibits autoantibody production triggered by immunization with human peptidyl arginine deiminase 4. 0.64
Maintenance of remission after tocilizumab withdrawal in patients with glucocorticoid‐dependent polymyalgia rheumatica 1.00
7 4.90
Predictive models for ataxia progression and conversion in spinocerebellar ataxia type 1 and 3 0.20
Distinct cerebellar networks underpin clinical improvement in adolescent Tourette disorder 0.88
A large cohort study of prenatal exome sequencing redefines diagnosis in fetal corpus callosum anomalies 1.00
Interferon-γ causes myogenic cell dysfunction and senescence in immune myopathies 1.00
Combined genomics and proteomics unveils elusive variants and vast aetiologic heterogeneity in dystonia 0.05
Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits 0.96
Ventriculitis characteristics and outcomes (VELCRO): an international retrospective cohort study 0.81
2 0.91
Treatment strategies for Boerhaave syndrome: multinational retrospective cohort study 0.08
Endovascular aortic arch repair with a triple branch arch device 0.83
2 1.11
The spatiotemporal dynamics of postnatal vascularization in the mouse brain 0.85
Genetic modifiers and ascertainment drive variable expressivity of complex disorders 0.26
2 0.63
The DanRI regulatory system in uropathogenic Escherichia coli subverts neutrophil responses 0.33
Immune profiling in subclinical secondary dengue-infected cases reveals adaptive immune signatures correlated to protection from severe dengue 0.29
2 0.74
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes 0.05
Sphingomyelins in mosquito saliva reconfigure skin lipidome to promote viral protein levels and enhance transmission of flaviviruses 0.69
1 1.00
Lanthanide complexes with acetophenone-based push-pull antennas as efficient MRI and two-photon microscopy imaging probes 1.00
4 1.55
Inspiratory effort and dynamic transpulmonary driving pressure in extremely preterm infants 0.44
Mass medical evacuations to decrease the intensive care burden: results from the TRANSCOV cohort study. 0.95
Low tidal volume ventilation and mortality in patients with acute brain injury: a secondary analysis of an international observational study* 0.10
Ultrathin bronchoscopy with radial endobronchial ultrasound and rapid on-site evaluation for the diagnosis of peripheral pulmonary lesions: a multicentre randomized controlled factorial trial 0.06
2 0.07
High-Dose vs. Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: The FLUNITY-HD Prespecified Pooled Analysis. 0.04
PIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations. 0.03
13 8.38
Switch to BIC/TAF/FTC or DTG + TDF/FTC in virologically suppressed PWH: outcomes in real-world setting with and without tenofovir resistance 1.00
Prophylactic Efficacy of CD388, a Novel Drug–Fc Conjugate, in a Human Influenza A/H3N2 Virus Challenge Model: A Randomized, Controlled Phase 2a Study 0.15
Characterizing Treatment Adherence Trajectories in the endTB Multisite Cohort of Drug-Resistant Tuberculosis Patients: An Application of Group-Based Trajectory Modeling 0.09
Therapeutic Drug Monitoring of Long-Acting Cabotegravir and Rilpivirine in a National Cohort of People With Human Immunodeficiency Virus Type 1: First Results From the ANRS-MIE CARLAPOP Study 1.00
Should We Extend the Use of Oral Antibiotics in Infective Endocarditis? The ENDO-ORAL Study 1.00
Background HIV Incidence in PURPOSE 1 and 2 PrEP Trials 1.00
Comparing clinical, microbiological and genetic definitions of relapse in patients with subsequent episodes of MRSA bone and joint infection 0.17
Kinetics of Non-nucleoside Reverse Transcriptase Inhibitor Resistance-associated Mutations in HIV-1 Proviral Cellular Reservoirs in NNRTI-experienced Persons 1.00
Weekly Screening of Circulating iMucorales/i DNA and early treatment in Severely Burned Patients Improves Survival: Real-Life Bi-center Experience in France 1.00
Consequences of stopping antiretroviral treatment in a persistently seronegative individual infected with HIV-1 1.00
Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study 0.09
iHistoplasma/i Antigenuria Prevalence in Patients With Advanced HIV Disease in Côte d’Ivoire: A Prospective Trial Ancillary Study 0.77
Risk of Cancer in People With Human Immunodeficiency Virus Experiencing Varying Degrees of Immune Recovery With Sustained Virological Suppression on Antiretroviral Treatment for More Than 2 Years: An International, Multicenter, Observational Cohort 0.11
7 3.17
The Influence of Older Age on RBC Transfusion Decisions in ICU Patients. 0.07
Discrepancies Between Point of Care and Central Laboratory Sodium and Potassium Measurements in ICU: Analytical Biases and Physician Awareness. 1.00
Utilization of Intensive Care Interventions in Critically Ill Patients With Candidemia Versus Bacteremia: A Multicenter Retrospective Cohort Study 0.03
Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study. 0.02
Impact of Conservative Vs. Liberal Extracorporeal Oxygen Target During Venoarterial Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock: A Pilot Randomized Control Trial. 0.95
Differentiating Lung From Chest Wall Mechanics Is Difficult Without Esophageal Manometry in Children With Acute Respiratory Distress Syndrome. 0.10
Effects of Sevoflurane Inhalation on Pulmonary Hemodynamics in Moderate to Severe Acute Respiratory Distress Syndrome Patients With Septic Shock: A Prospective Cohort Study. 1.00
6 4.76
Poly-immunity arrays associated with Rhs toxins confer wide protection against competitors 0.71
Modulation of relative aversive and safety learning by D2-expressing neurons of the anterior paraventricular nucleus of the thalamus 1.00
A common serial structure causes offline excitability changes linked to generalization between different memory types 0.33
Motivational control is implemented by a cingulo-prefrontal network 1.00
Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army 0.71
The Arp2/3 complex maintains gut epithelial integrity under mechanical challenge 1.00
1 0.07
BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay 0.07
2 1.10
GLP-1 Receptor Agonists Are Associated With Reduced Mortality Following Diabetic Foot Ulcers: A Nationwide Observational Study. 1.00
Relationship Between Metabolic and Histological Responses in People With Metabolic Dysfunction-Associated Steatohepatitis With and Without Type 2 Diabetes: Participant-Level Exploratory Analysis of the SYNERGY-NASH Trial With Tirzepatide. 0.10
1 0.09
Effect modification of serum omega-3 fatty acids on the associations between urinary phthalate biomarkers mixture and pregnancy outcomes among women seeking fertility care. 0.09
4 3.08
Liver steatosis induced by per- and polyfluoroalkyl substances exerts a limited influence on heterocyclic aromatic amine–mediated DNA damage at population-relevant exposure levels 1.00
Inhibition of human organic anion transporter 4 (OAT4) activity by bisphenol analogues 1.00
Environmental exposure to endocrine disruptors induces insulin resistance and hepatic inflammation in adult male rats, with partial transmission across subsequent generations 0.94
Assessment of the effects of estetrol and 17α-ethinylestradiol on zebrafish (Danio rerio) metamorphosis: a morphological and transcriptomic approach 0.14
4 1.41
Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis 0.03
Using eye tracking to evaluate cognitive and visual outcomes of early life phenol exposure 0.73
Acute exposure to environmental doses of di-n-butyl phthalate but not di-2-ethylhexyl phthalate induces mortality in isolated and cold-stressed workers of Bombus terrestris L. (Hymenoptera: Apidae) 0.50
Adolescent exposure to benzophenone ultraviolet filters: cross-sectional associations with obesity, cardiometabolic biomarkers, and asthma/allergy in six European biomonitoring studies 0.15
2 0.13
Systematic Revelation of the Metabolic Fate of Typical Quaternary Ammonium Compounds in Wheat Seedlings 0.08
Prenatal Exposure to Mixtures of Nonpersistent Endocrine-Disrupting Chemicals and Angiogenic Biomarkers, Placental Function, and Fetal Growth 0.05
2 0.30
Accelerated vascular ageing after COVID-19 infection: the CARTESIAN study 0.14
Acute pulmonary embolism: a multimarker calculator to predict short-term outcomes 0.17
2 0.21
RESECT: A Randomised Controlled Trial of Audit and Feedback in Non–muscle-invasive Bladder Cancer Surgery 0.00
Duration of Androgen Suppression with Postoperative Radiotherapy (DADSPORT) for Nonmetastatic Prostate Cancer: A Collaborative Systematic Review and Meta-analysis of Aggregate Data 0.21
1 1.00
The natural history of gastroesophageal varices in children with portal hypertension 1.00
9 2.83
Novel insights into autoimmune gastritis: clinical profile and gastric neoplastic risk from an international multicentre study 0.09
Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes 0.13
<atl>Novel imyo/i -inositol to butyrate fermentation pathway in the prevalent human gut species iDysosmobacter welbionis,/i a bacterium associated with improved metabolic and liver health</atl> 0.25
First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia 0.10
Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data 0.89
Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort 0.42
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies 0.01
Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease 0.18
Toxic microbiome and progression of chronic kidney disease: insights from a longitudinal CKD-Microbiome Study 0.76
7 1.47
Original research: Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency. 0.03
Head-to-head comparison between vibration-controlled transient elastography and histology in predicting liver-related events due to metabolic dysfunction-associated steatotic liver disease. 0.18
Predictors of fibrosis, clinical events and mortality in MASLD: Data from the Global-MASLD study. 0.02
Serum bile acid levels predict the development of portal hypertension and high-risk esophageal varices following successful Kasai in biliary atresia. 1.00
Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study. 0.02
Association between longitudinal weight change and clinical outcome in individuals with MASLD. 0.17
Point-of-care ultrasound (POCUS)-guided volume management and the effect of cirrhotic cardiomyopathy on acute kidney injury outcomes in cirrhosis. 0.06
2 1.10
Fertility preservation and counselling in prepubertal and pubertal girls with Turner syndrome 1.00
Preimplantation genetic testing for neurofibromatosis type 1: molecular genetic aspects and impact on reproductive counseling 0.10
2 0.10
A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation 0.07
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis 0.04
1 0.29
Exploring a Rigid Macrocyclic Ligand Bearing Malonate Pendants for Gd(III) Complexation: the Coordination Chemistry of [Gd(OPDMA)]− 0.29
3 1.30
Inversed impaired osteogenic activity in children with severe obesity due to deficiency compared to and deficiency 0.25
Investigating the trend of revisional bariatric surgery, the complications, and associated risk factors in France 1.00
Sex-specific longitudinal associations between repeatedly measured movement behaviours and adiposity measures in school-aged children: a compositional data analysis approach 0.05
2 0.08
High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Diabetes 0.03
Transfusion Strategy Effect on Quality of Life in Patients With Myocardial Infarction and Anemia 0.05
2 0.25
Mental Health Antecedents and Correlates of 2 Distinct Developmental Pathways to Suicidal Ideation 0.08
Framework for Brain-Derived Dimensions of Psychopathology 0.17
2 1.19
Oncologic Risk of Missed Appendiceal Tumors in Acute Appendicitis 1.00
Diagnostic Accuracy of Imaging in Assessing Nonviability of Disappearing Colorectal Liver Metastasis 0.19
7 3.43
Restrictive vs Liberal Physical Restraint Strategies in Critically Ill Patients 1.00
Age-Adjusted D-Dimer Cutoff Levels to Rule Out Deep Vein Thrombosis 0.33
Discordance in Creatinine- and Cystatin C–Based eGFR and Clinical Outcomes 0.04
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock 0.00
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.06
Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury 1.00
Meningeal Embolization for Preventing Chronic Subdural Hematoma Recurrence After Surgery 1.00
6 3.93
Targeting Nipah virus replication: A fluorescence polarization assay for high-throughput modulators screening against the NTAIL–XD interaction 1.00
The butyrate-producing Gram-positive human gut bacterium, Hoskinsella mucinilytica, selectively targets host mucin N-acetylhexosamines 0.07
Identification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins 0.04
Cell wall arabinogalactan is responsible for Fungitell® cross reactivity in nocardiosis 0.82
Argonaute 1 contributes to the transcriptional silencing of HIV-1 1.00
Molecular recognition of fungal methylated glucosylceramides by ETD151 defensin 1.00
3 1.03
Three-Dimensional Geometry of the Normal Scapula: A Software Analysis. 0.86
Impact of Stem Design on Periprosthetic Femoral Fracture Risk 0.08
The T4-L1-Hip Axis Objectifies the Roussouly Classification Using Continuous Measures. 0.09
11 6.21
Circulating levels of ghrelin and hyperphagia in patients with rare genetic neurodevelopmental disorders 1.00
Clinical spectrum of extreme insulin resistance syndromes treated with rhIGF-1: A single-center experience 0.10
Immune Checkpoint Inhibitor Therapy for Aggressive Pituitary Neuroendocrine Tumors 0.06
Assessment of GFR Estimation Methods in Patients with Obesity 1.00
Challenges in Estimating Renal Function in X-linked Hypophosphatemia because of formula Overestimation and FGF23 Effects 1.00
Facial Analysis in Acromegaly Using Machine Learning: Toward Earlier Diagnosis 0.04
A Recurrent Splice Variant Sheds Light on 11β-Hydroxylase Deficiency in a Unique Large Cohort 0.96
Early Growth Hormone Treatment Enhances Growth and Nutritional Status in Silver-Russell Syndrome 1.00
A Global Approach to the Long-Term Follow-up of 17 Families with Bilateral Macronodular Adrenal Disease 0.17
Course of Pregnancies and Occurrence of Acute Pancreatitis in Women With Chylomicronemia 0.45
Near-Adult Height Outcomes in Patients Treated With rhIGF-1 for Severe Growth Failure: Real-World IGFD Registry Data 0.43
2 0.22
Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome 0.07
Divergent TIR signaling domains in TLR7 and TLR9 control opposing effects on systemic autoimmunity 0.15
2 2.00
Postoperative Hepatic Arterial Infusion With Oxaliplatin After Surgery of Four or More Colorectal Liver Metastases: A Randomized Phase II Trial. 1.00
Nivolumab ± Ipilimumab in Patients With Pretreated Advanced Neuroendocrine Carcinoma: The GCO-001 NIPINEC Randomized Phase II Trial. 1.00
12 2.94
Quantitative regression of qFibrosis with resmetirom: Exploratory histologic endpoints from the MAESTRO-NASH phase III clinical trial 0.09
Incidence and implications of abstinence-induced recompensation in alcohol-related cirrhosis 0.08
Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis 0.14
Intratumour Ploidy Heterogeneity and Clonal Evolution in Hepatocellular Carcinoma 1.00
Predicting hepatic decompensation using non-invasive tests in a contemporary multicentre cohort of patients with cACLD 0.12
Refining the Baveno VII criteria for clinically significant portal hypertension: an individual-patient data meta-analysis 0.10
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials 0.08
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.18
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.07
Effect of rifaximin in patients with severe cirrhosis and ascites: A randomized double-blind placebo-controlled clinical trial 1.00
Impact of first and further decompensation in patients with compensated ACLD due to MASLD 0.03
Safety and efficacy of elafibranor in primary sclerosing cholangitis: The ELMWOOD phase II randomized-controlled trial 0.05
11 4.22
Disease-Attenuated Pneumococcal Biosynthesis Gene Mutants Invade the Mucosal Epithelium and Induce Innate Immunity 0.07
Treatment Monitoring and Outcome Prediction in Invasive Aspergillosis Using Immunologic Markers 0.04
Methicillin-Resistant Staphylococcus aureus Bacteremia Relapses Show Diverse Genomic Profiles but Convergence in Bacteremia-Associated Genes 0.10
In Vivo Risk Assessment of Yellow Fever Virus Transmission Through Breastfeeding, and Mechanistic Insights 1.00
Chronic malaria is associated with trauma-related splenic rupture requiring splenectomy 0.04
Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness 0.05
Single-cell transcriptome profiling reveals the immune dysregulation characteristics of mice infected by iBrucella abortus/i 0.07
Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccination Against Hospitalizations and Deaths According to Frailty Score: A Post Hoc Analysis of the DANFLU-1 Randomized Trial 0.10
Cytolethal Distending Toxin-increased DNA damage and ploidy involve the YAP/TAZ-TEAD signaling pathway 1.00
γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1 1.00
Seroepidemiological Reconstruction of Long-term Rift Valley Fever Virus Circulation in Nouakchott, Mauritania 0.75
2 1.13
5imilar Response Dynamics Represent Opposite Behaviors and Rewards in Frontal Cortex 0.13
Optimal foraging requires coordinating decisions with movements 1.00
5 2.90
Multiple bursting patterns in lateral habenula neurons: Experiments and computational model 0.22
Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations 0.92
Capillary‐to‐sarcolemma distance and location of cytochrome c oxidase: Insights for maximal O2 uptake and muscle lactate release in trained athletes 1.00
Non‐homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity 0.36
Muscle regeneration is improved by hot water immersion but unchanged by cold following a simulated musculoskeletal injury in humans 0.40
2 1.07
Optimizing patient blood management through intraoperative goal-directed fluid therapy protocol within an enhanced recovery after cardiac surgery program 1.00
Intercostal Cryoanalgesia for Acute Pain after VATS Lung Resection (CRYO-VATS): a randomized controlled preliminary trial 0.07
7 3.96
Infection risk among psoriasis biologic-new users: a cohort study on the French National Health Data System 1.00
Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension 0.06
Ultraviolet induced fluorescent dermoscopy for the diagnosis of skin tumors: A multicenter study 0.05
Risk factors for recurrence or relapse after a first episode of adult IgA vasculitis: a multicenter retrospective study 0.90
Efficacy and Safety of Cosibelimab in Advanced Cutaneous Squamous Cell Carcinoma: Results From a Pivotal Open-label Study With a Median Follow-up of ≥2 Years 0.26
Chronic skin conditions and life trajectories: development and validation of “Dermatology Long-Term Life Impact Measure (DLLIM)” 0.69
Genomic and clinical characterization of anogenital basal cell carcinoma: a retrospective and prospective cohort study 1.00
3 2.26
A Deep-Red-Absorbing Osmium(II)-Based Photosensitizer Evokes Pyroptosis by Targeting Glutamine Metabolism and Impairing Cell Redox Homeostasis 1.00
Wall Teichoic Acids Are Direct Molecular Targets of Antimicrobial Peptides in Gram-Positive Bacteria 0.30
Selection of Ruthenium Polypyridyl Complex-Modified Aptamers for Photodynamic Therapy against Streptococcus Pneumonia 0.96
8 2.39
Chlorhexidine vs Povidone-Iodine Alcohol Solutions for Cardiac Implantable Electronic Devices A Prospective Randomized Study 1.00
High-Dose vs Standard-Dose Influenza Vaccine in Chronic Kidney Disease The DANFLU-2 Trial Subgroup Analysis 0.03
Effect of ECMO Flow Variations on Pulmonary Capillary Wedge Pressure in Patients With Cardiogenic Shock 0.94
Adiposity-Related Anthropometrics and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction A Participant-Level Pooled Analysis of Randomized Clinical Trials 0.06
Impact of Vutrisiran on Cardiac Biomarkers in Patients With Transthyretin Amyloidosis With Cardiomyopathy From HELIOS-B 0.06
Effects of Vutrisiran on Cardiac Function and Outcomes in Patients With Transthyretin Amyloidosis With Cardiomyopathy 0.08
Vutrisiran Improves Survival and Reduces Cardiovascular Events in ATTR Amyloid Cardiomyopathy HELIOS-B 0.10
Effect of Empagliflozin on the Mechanisms Driving Erythropoiesis and Iron Mobilization in Patients With Heart Failure The EMPEROR Program 0.11
5 2.18
Effect of Finerenone on Morbidity and Mortality in CKD. 0.04
Measurement, Estimation, and Correlates of the Glomerular Filtration Rate before and after Bariatric Surgery. 0.17
Identification of Renal Transcripts Associated with Kidney Function and Prognosis in ANCA-Associated Vasculitis. 0.93
Histologic Features Associated with Kidney Survival in Scleroderma Renal Crisis. 1.00
Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci. 0.04
5 1.24
Tattoos and risk of cutaneous melanoma and non-melanoma skin cancer in France 0.80
Lipid biomarkers of habitual alcohol intake and associations with pancreatic cancer risk 0.06
Tattooing and risk of melanoma: a population-based case-control study in Utah 0.02
Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study 0.30
Trends in the incidence of cancers related to HIV-AIDS in Harare, Zimbabwe 1990-2019 0.06
8 5.05
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy 0.11
Parathyroid hormone suppression profiles following oral calcium challenge in kidney transplant recipients 1.00
A national cohort study examined the risk of severe infection and infection-related mortality in patients with chronic kidney disease with lupus nephritis in comparison to other chronic kidney disease etiologies 0.06
Mono-allelic pathogenic variants in JAG1 cause Autosomal Dominant Tubulo-interstitial Kidney Disease (ADTKD-JAG1) 0.90
Mineralocorticoid receptor inhibition in parietal epithelial cells prevents focal segmental glomerulosclerosis and crescentic glomerulonephritis. 0.93
A stronger type I interferon signature distinguishes ANCA-associated vasculitis phenotypes and predicts kidney prognosis 0.76
Integrated spatial and functional metabolic profiling identified the thick ascending limb as a mitochondrial vulnerability hub in acute kidney injury 0.35
Medium chain fatty acids are potent binding competitors to improve protein-bound uremic toxin clearance during hemodialysis 0.92
9 3.05
A longitudinal DNA methylation atlas and its link to brain structure and mental health 0.20
Stress-induced plasminogen activator inhibitor-1 (PAI-1) as a blood biomarker and brain risk factor for PTSD 1.00
A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants 0.44
Psychotropic medications and their interactions with subcortical brain volume in bipolar disorder: An ENIGMA mega-analysis 0.01
Quantitative monitoring of ketamine’s impact on synaptic density using 11C-UCB-J PET imaging in the corticosterone mouse model of anxiety/depression 1.00
The psychedelic phenethylamine 25C-NBF, a selective 5-HT2A agonist, shows psychoplastogenic properties and rapid antidepressant effects in male rodents 0.13
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.00
GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy 0.13
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth 0.14
9 2.56
Prefrontal neural geometry of learned cues guides motivated behaviours 0.54
Albumin orchestrates a natural host defence mechanism against mucormycosis 0.05
Prevalence of Alzheimer’s disease pathology in the community 0.01
Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing 0.20
Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae 0.03
Maternal stress triggers early-life eczema through fetal mast cell programming 0.73
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury 0.04
Kupffer cell programming by maternal obesity triggers fatty liver disease 0.01
Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin 0.94
81 30.98
Clec3b⁺ fibroblasts are the primary effectors of portal fibrosis following activation via a KLF4/periostin axis 0.18
A family of ribosome hibernation factors widespread in Archaea 1.00
Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA interference response 0.06
Cross-species transcriptomics identify mineralocorticoid receptor pathway overactivation as a central driver of ocular rosacea 0.95
Investigating antibody cross-reactivity and transmission dynamics of alphaviruses and flaviviruses using a multiplex serological assay 0.58
CD73high fibroblasts orchestrate keratinocyte inflammation in the psoriasis-associated epithelial immune microenvironment 0.07
Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system 0.73
Subcellular reorganization upon phage infection reveals stepwise assembly of viral particles from membrane-associated precursors 0.62
Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still’s disease 0.11
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.09
Phage-steering permits antibody-mediated clearance of E. coli K1 from the gut 0.11
Segmented filamentous bacteria are worldwide human gut commensals 0.56
Post-treatment SIV control is associated with specific features of viral persistence before and after treatment interruption 0.94
Disrupted temperature-sleep coupling mechanism in a Dravet syndrome mouse model 0.27
Maintenance of intestinal CX3CR1+ macrophage homeostasis defines post-treatment control in SIV-infected macaques 1.00
Loss-of-function variants in the CAPN1 activator cause X-linked spastic ataxia 0.01
Competing cognitive pressures on human exploration in the absence of trade-off with exploitation 1.00
Latent transition analysis for longitudinal studies of post-acute infection syndromes 0.03
Multicountry genomic analysis underscores regional cholera spread in Africa 0.02
Miniature endoscope for high resolution electrophysiological recordings from the colon of live mice 0.09
Biomarker-integrated prognostic stagings for Alzheimer’s Disease 0.01
Electrographic cue-reactivity co-localizes with accumbens deep brain stimulation in a case of opioid use disorder 0.07
Targeting mGlyR with nanobodies for depression 0.23
Interaction and functional specialization across a distributed neural circuit for flexible task control in macaques 0.12
Using the linear references from the pangenome to discover missing autism variants 0.02
Endothelin-3 and T-type Ca2+ channels drive enteric neural crest cell calcium activity, contractility and migration 1.00
Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis 0.05
Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants 1.00
A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions 0.30
AI-powered SPOT imaging for enhanced myocardial scar detection and quantification 0.92
A synthetic cell phage cycle 0.25
Development of a replication-defective mpox virus platform for fundamental and therapeutic research 0.22
Circadian rhythm profiles derived from accelerometer measures of the sleep-wake cycle in two cohort studies 0.78
Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations 0.05
Anti-neuraminidase and anti-HA stalk antibodies reduce the susceptibility to and infectivity of influenza A/H3N2 virus 0.14
Early intrinsic excitability plasticity of neocortical engram neurons defines memory formation and precision 0.97
The NMDA receptor subunit GluN2D is a potential target for rapid antidepressant action 0.04
Oligomerisation of Ku from Mycobacterium tuberculosis promotes DNA synapsis 0.11
Polymerase theta repairs persistent G1-induced DNA breaks in S-phase during class switch recombination 0.78
Neural variability in the medial prefrontal cortex contributes to efficient adaptive behavior 0.92
Plasma p-tau217 as a biomarker of Alzheimer’s disease pathology in individuals with Down syndrome 0.01
Probabilistic classification of late treatment failure in uncomplicated falciparum malaria 0.20
Distinct autoreactive CD19 plasma cell subsets accumulate in lupus-prone mice 0.04
Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii 1.00
Proteome atlas for mechanistic discovery and risk prediction of diabetic retinopathy 0.02
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.01
Polygenic viral factors enable efficient mosquito-borne transmission of African Zika virus 0.54
Multi-lens ultrasound arrays enable large scale three-dimensional micro-vascularization characterization over whole organs 1.00
Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes 0.08
DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms 0.10
Eosinophil CD48 interactions with Candida albicans Als6 is protective in vitro and in mouse systemic candidiasis 0.05
Backtracking metabolic dynamics in single cells predicts bacterial replication in human macrophages 1.00
Deep mutational scanning of the human insulin receptor ectodomain to inform precision therapy for insulin resistance 0.13
Empathi: embedding-based phage protein annotation tool by hierarchical assignment 0.40
Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins 0.04
Dopamine dynamics during stimulus-reward learning in mice can be explained by performance rather than learning 0.29
Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites 0.10
Unlocking data in Klebsiella lysogens to predict capsular type-specificity of phage depolymerases 0.13
Rising dengue risk with increasing El Niño–Southern Oscillation amplitude and teleconnections 0.05
Pvf1-Pvr-mediated crosstalk between trachea and gut guides intestinal stem cell migration to promote gut regeneration 0.22
A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior in male mice 0.28
CCR7+ dendritic cells expressing both IL-23A and IL-12B potentially contribute to psoriasis relapse 0.03
Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious 0.12
Dengue virus susceptibility in linked to natural cytochrome P450 promoter variants 0.89
In vivo antimicrobial activity of engineered mesoporous silica nanoparticles targeting intracellular mycobacteria 0.69
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge 0.06
Higher-order and distributed synergistic functional interactions encode information gain in goal-directed learning 0.56
Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems 0.25
An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs 0.21
Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics 0.04
Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin in preclinical models 1.00
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge 0.01
Striatal astrocytes modulate behavioral flexibility and whole-body metabolism in mice 1.00
Genetic risk-dependent brain markers of resilience to childhood Trauma 0.14
Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety-like behaviors 1.00
Safety and efficacy of 3- and 5-day regimens of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial 0.58
Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy 0.73
Combining dynamin 2 myopathy and neuropathy mutations rescues both phenotypes 1.00
Adjunctive phage therapy improves antibiotic treatment of ventilator-associated-pneumonia with Pseudomonas aeruginosa 0.20
Tinnitus risk factors and its evolution over time 0.36
T cell toxicity induced by tigecycline binding to the mitochondrial ribosome 0.09
1 0.00
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling 0.00
1 0.29
Representational dynamics during extinction of fear memories in the human brain 0.29
3 0.94
Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses 0.83
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy 0.06
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis 0.05
9 0.41
Antisense oligonucleotide-mediated knockdown therapy in two infants with severe epileptic encephalopathy 0.03
Semaglutide on liver fibrosis and heart outcomes in patients at high risk of liver fibrosis: a prespecified analysis of the SELECT randomized trial 0.04
Deleterious coding variation associated with autism is shared across ancestries 0.01
Deciphering the etiology of the 2024 outbreak of undiagnosed febrile illness in Panzi, Democratic Republic of the Congo 0.03
Fecal microbiota transplantation plus immunotherapy in non-small cell lung cancer and melanoma: the phase 2 FMT-LUMINate trial 0.16
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.00
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure 0.04
A full life cycle biological clock based on routine clinical data and its impact in health and diseases 0.02
Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial 0.08
3 1.78
Deconstruction of a memory engram reveals distinct ensembles recruited at learning 0.58
Facial expressions in mice reveal latent cognitive variables and their neural correlates 0.19
Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits 1.00
8 2.86
Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes 0.08
A cortico-subthalamic circuit rapidly engages and releases inhibition of specific movements depending on the environmental context 0.13
Plug-and-play evolution of the Klebsiella pneumoniae capsule locus enables serotype exchange across genetic backgrounds 1.00
Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci 0.13
Temperate phage evolve to integrate host stress and quorum signals in lysis–lysogeny decisions 0.33
Uropathogenic Escherichia coli proliferate as a coccoid morphotype inside human host cells 0.08
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms. 0.11
The prefrontal cortex encodes task-identity information and flexibly adjusts its sensory processes as a function of the specific ongoing task 1.00
2 1.83
Ripply3 overdosage induces mid-face shortening through Tbx1 downregulation in Down syndrome models 1.00
Deciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile 0.83
1 0.18
Diagnostic accuracy of the WHO tuberculosis treatment decision algorithms for children with presumptive tuberculosis: An individual participant data meta-analysis 0.18
23 8.29
Erythroferrone derived from osteoblasts regulates stress erythropoiesis 0.07
Podocin oligomers regulate the ordering of nephrin chains, providing the molecular basis of NPHS2 interallelic interactions 0.12
Smooth-to-rough morphotype switching, a mechanism of phage resistance in Mycobacterium abscessus 0.20
Probabilistic mapping and automated segmentation of human brainstem white matter bundles 0.07
Integration of fear learning and fear expression across the dorsoventral axis of the hippocampus 1.00
Maladaptive immunity to the microbiota promotes neuronal hyperinnervation and itch via IL-17A 0.13
Reward-driven adaptation of movements requires strong recurrent basal ganglia–cortical loops 1.00
The olfactory bulb endocast as a proxy for mammalian olfaction 0.13
Genetics of prelingual isolated deafness and Usher syndrome in the Maghreb and Jordan: Harnessing the potential of homozygosity 0.17
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination 0.10
Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery 0.38
Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease 0.11
Structural pores not required: Antimicrobial peptides induce ion permeabilization of lipid membranes through transient water channels 0.25
Logarithmic coding leads to adaptive stabilization in the presence of sensorimotor delays 1.00
Microtubule remodeling by the innate immune factor Trim69 compromises dynein-dependent migration of HIV virion cores toward the nucleus 1.00
Evolving choice hysteresis in reinforcement learning: Comparing the adaptive value of positivity bias and gradual perseveration 1.00
A recurrent de novo damaging variant in EMP2 causes progressive symmetric erythrokeratoderma 0.18
Classical BSE emergence from Nor98/atypical scrapie: Unraveling the shift vs. selection dichotomy in the prion field 0.11
Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAΦ 0.50
Unraveling the role of rat and flea population dynamics on the seasonality of plague epidemics in Madagascar 0.33
The great phage escape: Activating and escaping lactococcal antiphage systems 0.23
Predicting high-fitness viral protein variants with Bayesian active learning and biophysics 0.13
Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses 0.07
1 1.00
Temporal power of a cycling sprinter: experiments and effective time theory 1.00
3 0.87
Prognostic Value of Global Longitudinal Strain using Automated Measurement in Cardiac MRI. 0.81
Impact of LI-RADS CT and MRI Ancillary Features on Diagnostic Performance: An Individual Participant Data Meta-Analysis. 0.02
Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis. 0.04
4 2.39
HNF1B integrates signals in a feed-forward loop driving kidney disease progression 0.83
Protein and genomic language models uncover the unexplored diversity of bacterial immunity 1.00
Population genomics of Anopheles darlingi, the principal South American malaria vector mosquito 0.13
Attenuation of virulence in Yersinia pestis across three plague pandemics 0.44
9 2.11
The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events 1.00
Bacteriophages mobilize bacterial defense systems via lateral transduction 0.22
Lipid self-assembly dependence on hyaluronic acid size reveals biolubrication and osteoarthritic degeneration mechanisms 0.08
Substitution of human olfaction by the trigeminal system 0.28
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate 0.05
Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches 0.05
Ethanol ingestion via frugivory in wild chimpanzees 0.08
Genetic foundations of interindividual neurophysiological variability 0.10
Direct and indirect striatal projecting neurons exert strategy-dependent effects on decision-making 0.25
5 3.14
The orphan receptor GPR84 drives inflammation in Buruli ulcer development 0.87
NKX6.1 mRNA copy number is an actionable biomarker associated with islet function and clinical outcomes after islet transplantation 0.81
Metabolic acidosis causes a Fanconi-like syndrome with intracellular trafficking defects and proximal tubule dysfunction 0.18
Epidemiological and antigenic inferences from serological cross-reactivity among arboviruses 0.29
<atl>Immune response and clinical severity are shaped by skin-adapted iStaphylococcus aureus/i in chronically infected patients</atl> 1.00
3 1.24
Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicentre, assessor blinded, cluster randomised clinical trial 1.00
Benefits and harms of ADHD interventions: umbrella review and platform for shared decision making 0.19
ADHD drug treatment and risk of suicidal behaviours, substance misuse, accidental injuries, transport accidents, and criminality: emulation of target trials 0.05
2 1.30
Iron limitation promotes metabolic cross-feeding between cheese ripening bacteria 1.00
Function-based selection of synthetic communities enables mechanistic microbiome studies 0.30
2 1.05
Remibrutinib in chronic spontaneous urticaria: 52-Week results from two phase 3 studies 0.05
Unraveling shared genetics across asthma subtypes and 81 asthma-related traits 1.00
7 2.30
A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial 0.07
Efficacy and safety of nipocalimab in patients with moderate-to-severe Sjögren's disease (DAHLIAS): a randomised, phase 2, placebo-controlled, double-blind trial 0.08
Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD): an individual-level pooled analysis 0.04
Cloxacillin versus cefazolin for meticillin-susceptible Staphylococcus aureus bacteraemia (CloCeBa): a prospective, open-label, multicentre, non-inferiority, randomised clinical trial 1.00
Efficacy and safety of single-anastomosis duodeno-ileal bypass with sleeve gastrectomy versus Roux-en-Y gastric bypass in France (SADISLEEVE): results of a randomised, open-label, superiority trial at 2 years of follow-up 1.00
Safety and efficacy of steroidal mineralocorticoid receptor antagonists in patients with kidney failure requiring dialysis: a systematic review and meta-analysis of randomised controlled trials 0.06
Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial 0.06
6 1.24
Safety, tolerability, pharmacokinetics, and efficacy of burosumab in infants with X-linked hypophosphataemia: an open-label, multicentre, non-randomised study 0.14
Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study 0.02
Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study 0.05
Treatments for MEN1-associated endocrine tumours: three systematic reviews and a meta-analysis 0.14
Once-weekly IcoSema versus multiple daily insulin injections in type 2 diabetes management (COMBINE 3): an open-label, multicentre, treat-to-target, non-inferiority, randomised, phase 3a trial 0.10
Surgery for the treatment of arterial hypertension in patients with unilateral adrenal incidentalomas and mild autonomous cortisol secretion (CHIRACIC): a multicentre, open-label, superiority randomised controlled trial 0.78
5 2.12
The aetiology and prevalence of preoperative anaemia in patients undergoing major surgery (ALICE): an international, prospective, observational cohort study 0.04
Melioidosis in Mali: a retrospective observational study 0.14
Plasmodium falciparum carriage in a population under long-term, intensive malaria control in Kedougou region, Senegal: a 1-year cohort study 0.64
Global burden of cancer attributable to HIV: a worldwide incidence analysis 1.00
Efficacy of non-pyrethroid indoor residual spraying or intensive behaviour change communication in combination with long-lasting insecticidal nets for malaria control in west Africa: a pragmatic, cluster-randomised, controlled trial 0.30
3 0.18
Specific midlife depressive symptoms and long-term dementia risk: a 23-year UK prospective cohort study 0.06
Comparison of antidepressant deprescribing strategies in individuals with clinically remitted depression: a systematic review and network meta-analysis 0.08
Efficacy and safety of iclepertin for cognitive impairment associated with schizophrenia (CONNEX programme): results from three phase 3 randomised controlled trials 0.05
14 2.00
Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI 0.11
Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism 0.03
Efficacy and Safety of Obinutuzumab in Active Systemic Lupus Erythematosus 0.04
Hematopoietic Stem-Cell Gene Therapy for Cystinosis 0.05
Deferring Arterial Catheterization in Critically Ill Patients with Shock 1.00
Belzutifan for Advanced Pheochromocytoma or Paraganglioma 0.12
Nexiguran Ziclumeran Gene Editing in Hereditary ATTR with Polyneuropathy 0.10
High-Dose Influenza Vaccine to Reduce Hospitalizations 0.04
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension 0.08
High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults 0.03
Proportional-Assist Ventilation for Minimizing the Duration of Mechanical Ventilation 0.17
Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis 0.09
Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma 0.07
Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis 0.09
1 1.00
Prognostic impact and safety of early adjunctive corticosteroid therapy in HIV-negative severe pneumocystis pneumonia: a propensity-matched multicentre study 1.00
1 1.00
The hospital sink drain biofilm resistome is independent of the corresponding microbiota, the environment and disinfection measures 1.00

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