Nature Search

Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathies

Variants in the PSMC5 gene impair proteasome function and cellular homeostasis, altering brain development in children. This study reveals underlying molecular mechanisms contributing to this neurodevelopmental phenotype, and suggests therapeutic leads for neurodevelopmental proteasomopathies.

Sébastien Küry
Janelle E. Stanton
Elke Krüger
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-21
Diploid sporophytic tissue in the seed of Cupressus sempervirens L.

Aristotelis C Papageorgiou
Research01 Nov 1998
Heredity

Volume: 81, P: 586-590
Minimally invasive implantation of scalable high-density cortical microelectrode arrays for multimodal neural decoding and stimulation

A 1,024-channel microelectrode array is delivered to the brain cortex via a minimally invasive incision in the skull and dura, and allows recording, stimulation and neural decoding across large portions of the brain in porcine models and human neurosurgical patients.

Mark Hettick
Elton Ho
Benjamin I. Rapoport
ResearchOpen Access02 Oct 2025
Nature Biomedical Engineering

P: 1-16
Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer

Daniel R. Barnes
Jonathan P. Tyrer
Paul D. P. Pharoah
ResearchOpen Access20 Nov 2025
npj Genomic Medicine

Volume: 10, P: 1-21
Herpes-like Epstein–Barr Virus in Leprosy

P. S. PAPAGEORGIOU
C. SOROKIN
P. R. GLADE
Research07 May 1971
Nature

Volume: 231, P: 47-49
Anti-C3 antibodies in neonatal saliva

J. F. PRICE
B. D. WILLIAMS
S. J. CHALLACOMBE
Research11 Sept 1975
Nature

Volume: 257, P: 146-147
A Spectrum Response Study on Single Strand DNA Breaks, Sister Chromatid Exchanges, and Lethality Induced by Phototherapy Lights

E G Sideris
G C Papageorgiou
Eva M Vitsa
Research01 Jul 1981
Pediatric Research

Volume: 15, P: 1019-1023
Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase

In this work, the authors report a three-step charge-driven coacervation model involving dynamic complexes between a positively charged IDR of human RECQ4 and G-quadruplexes. The IDR also interacts with Replication Protein A, implying RECQ4’s regulatory role.

Anna C. Papageorgiou
Michaela Pospisilova
Konstantinos Tripsianes
ResearchOpen Access24 Oct 2023
Nature Communications

Volume: 14, P: 1-19
Fetal-specific DNA methylation ratio permits noninvasive prenatal diagnosis of trisomy 21

Noninvasive testing for Down's syndrome (trisomy 21) would greatly reduce the risks associated with the more invasive techniques used currently. Earlier identification of differentially methylated regions between fetal DNA and maternal peripheral blood has now enabled Elisavet Papageorgiou and her colleagues to develop a strategy involving methylated DNA immunoprecipitation in combination with real-time quantitative PCR that discriminates normal from trisomy 21 cases in maternal peripheral blood with high sensitivity.

Elisavet A Papageorgiou
Alex Karagrigoriou
Philippos C Patsalis
Research06 Mar 2011
Nature Medicine

Volume: 17, P: 510-513
Increasing blood pressure predicts levels of circulating neutrophil extracellular traps in untreated hypertensive patients

These authors contributed equally.

A. Malliora
A. Lazaridis
E. Gkaliagkousi
Research14 Aug 2025
Hypertension Research

Volume: 48, P: 2688-2700
Adenosine–deaminase–deficient mice die perinatally and exhibit liver–cell degeneration, atelectasis and small intestinal cell death

Alexandra A.J. Migchielsen
Marco L. Breuer
Dinko Valerio
Research01 Jul 1995
Nature Genetics

Volume: 10, P: 279-287
Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

AtEH/Pan1 proteins contain two N-terminal Eps15 homology (EH) domains and are subunits of the endocytic TPLATE complex present in plants. Here, the authors combine X-ray crystallography, NMR and MD simulations with biochemical and in planta analysis to characterize the two AtEH1/Pan1 EH domains and reveal their structural differences and complementary functional roles.

Klaas Yperman
Anna C. Papageorgiou
Daniel Van Damme
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-11
Genetic structure and differentiation among Greek brown trout (Salmo trutta L.) populations

Y Karakousis
C Triantaphyllidis
Research01 Jun 1990
Heredity

Volume: 64, P: 297-304
Seismic sequences in Greece interpreted in terms of barrier model

G. F. Karakaisis
B. G. Karacostas
B. C. Papazachos
Research01 May 1985
Nature

Volume: 315, P: 212-214
An IgG autoantibody which inactivates C1¯-inhibitor

J. Jackson
R. B. Sim
C. Feighery
Research23 Oct 1986
Nature

Volume: 323, P: 722-724
DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts

Epigenetic therapies are known to synergize with immunotherapies through the de-repression of endogenous retroviral element (ERV)-encoded promoters. Here the authors identify treatment-induced neoantigens and validate their ability to induce T cell response and anti-tumor effects in vitro and in patient samples.

Ashish Goyal
Jens Bauer
Christoph Plass
ResearchOpen Access23 Oct 2023
Nature Communications

Volume: 14, P: 1-19
A longitudinal MRI dataset of brain metastases with tumor segmentations, clinical & radiomic data

Dimitra Flouri
Christos-Panagiotis Papanikas
Vasileios Vavourakis
ResearchOpen Access19 Nov 2025
Scientific Data

Volume: 12, P: 1-7
Homo-coupling of terminal alkynes on a noble metal surface

Acetylenes can be covalently linked by oxidative coupling reactions. Zhanget al. report terminal alkyne C_sp-H bond activation and concomitant homo-coupling on a silver surface, yielding polymeric networks with a conjugated backbone.

Yi-Qi Zhang
Nenad Kepčija
Johannes V. Barth
Research18 Dec 2012
Nature Communications

Volume: 3, P: 1-8
Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

There are currently no drugs available to treat SARS-CoV-2 infection. A promising alternative treatment for COVID-19 patients is convalescent plasma. Here, Gharbharan et al. collect covalescent plasma and report no overall clinical benefit for 86 patients hospitalized for COVID-19 and treated with 300 mL convalescent plasma.

Arvind Gharbharan
Carlijn C. E. Jordans
Bart J. A. Rijnders
ResearchOpen Access27 May 2021
Nature Communications

Volume: 12, P: 1-12
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG

High intracellular concentrations of the α-ketoglutarate analog N-oxalylglycine, owing to MCT2-mediated transport of its newly described prodrug MOG, inhibit multiple enzymes in glutamine metabolism and selectively kill MCT2-expressing cancer cells.

Louise Fets
Paul C. Driscoll
Dimitrios Anastasiou
Research08 Oct 2018
Nature Chemical Biology

Volume: 14, P: 1032-1042
Pulmonary Uptake of Liposomal Phosphatidylcholine

Richard D Zachman
Francis H C Tsao
Research01 Jan 1980
Pediatric Research

Volume: 14, P: 24-27
Comparison of Red Cell Transfusion and Polyethylene Glycol-Modified Adenosine Deaminase Therapy in an Adenosine Deaminase-Deficient Child: Measurement of Erythrocyte Deoxyadenosine Triphosphate as a Useful Tool

C Bory
R Boulieu
M Hershfield
Research01 Aug 1990
Pediatric Research

Volume: 28, P: 127-130
Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)

The authors demonstrate a real-time, non-invasive, far-field optical probe to monitor particle size distribution in pharmaceutical manufacturing. It characterizes the speckle scattered from the surface using machine learning weaved into optical physics.

Qihang Zhang
Janaka C. Gamekkanda
George Barbastathis
ResearchOpen Access01 Mar 2023
Nature Communications

Volume: 14, P: 1-9
The Effect of Glucocorticoids on Plasma Insulin-Like Growth Factor I Concentration in the Rat Fetus

H David Mosier Jr.
E Martin Spencer
Regina A Jansons
Research01 Jul 1987
Pediatric Research

Volume: 22, P: 92-95
Observation of electroweak production of two jets and a Z-boson pair

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access09 Feb 2023
Nature Physics

Volume: 19, P: 237-253
The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis

Michael M Fuenfer
Victor C Herson
Peter J Krause
Research01 Aug 1987
Pediatric Research

Volume: 22, P: 150-153
Effects of Prenatal Dexamethasone on Development of Ornithine Decarboxylase Activity in Brain and Peripheral Tissues of Rats

Hernan A Navarro
Jean Lachowicz
Theodore A Slotkin
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 465-469
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

Indirect DNA damage to cells cultured below a cellular barrier caused by nanoparticles occurs across barriers containing two or more layers, but not monolayer barriers, suggesting that the thickness of the cell barrier is important in signalling.

A. Sood
S. Salih
C. P. Case
Research06 Nov 2011
Nature Nanotechnology

Volume: 6, P: 824-833
Test of the universality of τ and μ lepton couplings in W-boson decays with the ATLAS detector

The ATLAS Collaboration reports a measurement of the ratio of the decay rates of W bosons to τ leptons and muons, in agreement with universal lepton couplings as postulated in the standard model of particle physics.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access05 Jul 2021
Nature Physics

Volume: 17, P: 813-818
Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

The ATLAS experiment at the Large Hadron Collider reports a search for charged-lepton-flavour violation in decays of Z bosons into a τ lepton and an electron or muon of opposite charge.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access01 Jul 2021
Nature Physics

Volume: 17, P: 819-825
Evidence for light-by-light scattering in heavy-ion collisions with the ATLAS detector at the LHC

Quantum electrodynamics predicts a rare process in which light is scattered by light. The ATLAS Collaboration reports signs of this elusive effect in the collisions of ultra-relativistic lead ions.

M. Aaboud
G. Aad
L. Zwalinski
ResearchOpen Access14 Aug 2017
Nature Physics

Volume: 13, P: 852-858
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Stig Bojesen, Georgia Chenevix-Trench, Alison Dunning and colleagues report common variants at the TERT-CLPTM1L locus associated with mean telomere length measured in whole blood. They also identify associations at this locus to breast or ovarian cancer susceptibility and report functional studies in breast and ovarian cancer tissue and cell lines.

Stig E Bojesen
Karen A Pooley
Alison M Dunning
Research27 Mar 2013
Nature Genetics

Volume: 45, P: 371-384
The suppression of star formation by powerful active galactic nuclei

Observations at submillimetre and X-ray wavelengths show that rapid star formation was common in the host galaxies of active galactic nuclei when the Universe was 2–6 Gyr old, but that the most vigorous star formation is not observed around powerful black holes, thereby confirming a key prediction of models in which an active galactic nucleus expels the interstellar medium of its host galaxy.

M. J. Page
M. Symeonidis
M. Zemcov
Research09 May 2012
Nature

Volume: 485, P: 213-216
Submillimetre galaxies reside in dark matter haloes with masses greater than 3 × 10¹¹ solar masses

The extragalactic background light at far-infrared wavelengths comes from optically faint, dusty, star-forming galaxies with star formation rates at the level of a few hundred solar masses per year. These faint submillimetre galaxies are challenging to study individually, but their average properties can be studied using statistics such as the angular power spectrum of the background intensity variations. This study reports excess clustering over the linear prediction at arcminute angular scales in the power spectrum of brightness fluctuations at 250, 350 and 500 micrometres. It is found that submillimetre galaxies are located in dark matter haloes with a minimum mass of log₁₀[M_min/solar mass]=11.5^+0.7_-0.2 at 350° micrometres.

Alexandre Amblard
Asantha Cooray
M. Zemcov
Research16 Feb 2011
Nature

Volume: 470, P: 510-512
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Paul Pharoah and colleagues report the results of a large genome-wide association study of ovarian cancer. They identify new susceptibility loci for different epithelial ovarian cancer histotypes and use integrated analyses of genes and regulatory features at each locus to predict candidate susceptibility genes, including OBFC1.

Catherine M Phelan
Karoline B Kuchenbaecker
Paul D P Pharoah
Research27 Mar 2017
Nature Genetics

Volume: 49, P: 680-691
Real world data on the prognostic significance of monocytopenia in myelodysplastic syndrome

Panagiotis T. Diamantopoulos
Emmanouil Charakopoulos
Athanasios Galanopoulos
ResearchOpen Access26 Oct 2022
Scientific Reports

Volume: 12, P: 1-8
Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG

Louise Fets
Paul C. Driscoll
Dimitrios Anastasiou
Amendments and Corrections23 Oct 2019
Nature Chemical Biology

Volume: 15, P: 1249
The evolving etiologies of rapidly progressive dementia: a systematic review

Mei-Hua Lei
Li-Juan Cao
Song Qiao
ReviewsOpen Access27 Nov 2025
Translational Psychiatry

Volume: 15, P: 1-7
MODULATION OF CHLORAMPHENICOL(C) BIOAVAILABILITY(F) BY PANCREATIC ENZYME REPLACEMENT (PRE) IN CYSTIC FIBROSIS (CF)

Chris J Dickinson
Stephen C Aronoff
Jeffrey L Blumer
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 151
From data to dialogue in setting research priorities for Lewy body dementia

Irina Kinchin
Rachel L. Fitzpatrick
Iracema Leroi
ResearchOpen Access04 Aug 2025
npj Dementia

Volume: 1, P: 1-10
RECIPROCAL INHIBITION OF CARDIAC RESPONSES TO NORE-PINEPHRINE AND INSULIN

Dov B Nudel
John C Lee
S Evans Downing
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 396
Surface anchors target golden bullets

Gold nanomaterials are attractive for a variety of applications, including in medicine, but need to be made stable enough to operate in biological systems. Now, gold nanorods have been stabilized for photothermal therapy by sequential surface anchoring, using a bidendate PEG-based ligand that features a thiolate moiety and an Au–NHC moiety.

Guillaume Médard
Anthoula C. Papageorgiou
News & Views14 Dec 2018
Nature Chemistry

Volume: 11, P: 20-22
PREVENTION OF HOMOCYTOTROPIC ANTIBODY RESPONSE IN RATS

Mirla F David-Faridy
J C Haworth
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 411
A pharmacogenetic study of ABCB1 polymorphisms and cyclosporine treatment response in patients with psoriasis in the Greek population

Y Vasilopoulos
C Sarri
T Sarafidou
Research03 Jun 2014
The Pharmacogenomics Journal

Volume: 14, P: 523-525
Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall

Sharan Ananthaseshan
Krzysztof Bojakowski
Piotr Religa
ResearchOpen Access11 Aug 2022
Scientific Reports

Volume: 12, P: 1-14
Contribution of sewage to occurrence of phosphodiesterase-5 inhibitors in natural water

Youngmin Hong
Ingyu Lee
Hyunook Kim
ResearchOpen Access04 May 2021
Scientific Reports

Volume: 11, P: 1-12
Betamethasone and the Rhesus Fetus: Effect on Lung Morphometry and Connective Tissue

Jeanne C Beck
Wayne Mitzner
Rachel Scott
Research01 Mar 1981
Pediatric Research

Volume: 15, P: 235-240
Vaginal host immune-microbiome-metabolite interactions associated with spontaneous preterm birth in a predominantly white cohort

Megan Cavanagh
Emmanuel Amabebe
Dilly O. Anumba
ResearchOpen Access26 Mar 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-23
958 MANAGEMENT OF INFANTS BORN UNDER CONDITIONS THAT ARE NOT ASEPTIC (INFANTS CONTAMINATED AT BIRTH)

Antoine K Fomufod
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 523
955 LARYNGEAL INDUCED APNEA IN THE CHEMODENERVATED PIGLET

S Allen Fagenholz
John C Lee
S Evans Downing
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 523

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