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Dissipative many body systems provide quantum-enhanced sensitivity to external near gap-closing points. Here, the authors demonstrate record sensitivity in a Rydberg-atomic platform in correspondence of folded hysteresis trajectories under external microwave driving

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Single-atom catalysts are promising for water treatment but remain difficult to produce at scale. This work presents a cascade fixation strategy that delivers kilogram-scale, high-loading single-atom catalysts with near 100% singlet-oxygen selectivity, providing efficient and stable antibiotic degradation.

Distributed quantum sensing typically requires shared reference frames to coordinate measurements. Here, authors develop a reversed-encoding protocol that circumvents this requirement, enabling Heisenberg-limited precision in quantum networks without frame alignment.

This work proposed a fully heterogeneous quantum network that connects diverse user systems and enables multiple quantum tasks. A software-defined quantum network structure is also proposed for coordinating network nodes and optimizing network performance. It paves the way for an open and versatile quantum internet.

Pcm1 bridges centrosome asymmetry and polarized endosome trafficking to regulate radial glia progenitor fate decisions, balancing self-renewal and differentiation in zebrafish and human cortical organoids.

Coherence is widely seen as essential for quantum source quality. Here, authors demonstrate on-chip photon states with increased brightness and purity using incoherent light. It reveals the mechanism of pump coherence and lowers the barrier for the generation of high-quality quantum states.

Quantum light sources are promising for quantum circuits, yet facing an inherent trade-off between multifunction and brightness. By leveraging a strategy based on parity-time symmetry, we demonstrate an on-chip quantum light source with programmable lifetime, achieving a 20-fold tuning range of lifetime and balanced photon-pairs generation rate.

This work presents a compact spectrometer using acoustic Brillouin scattering on a hybrid chip, achieving a 0.56 nm resolution in a 1 mm waveguide without an optical pump.

Alkene-terminated silicon carbide surfaces are proposed as a room-temperature divacancy spin qubit quantum sensor suitable for bioimaging and nanoscale nuclear spin sensing.

Optical frequency combs power technologies like communication but face stability issues in miniaturization. Here, authors present a self-locked microcomb in a lithium niobate chip by combining electro-optic, Kerr, and Raman effects, achieving a 300 nm span and low noise without external feedback.

The function and regulatory mechanism of mRNA acetylation modification in cancer progression remains largely unknown. Here the authors identify that targeting tumor N4-acetylcytidine (ac4C) RNA acetyltransferase NAT10 improves anti-tumor response via MYC/CDK2/DNMT1/dsRNA/type I IFN pathway, and show the synergic anti-tumor effect of NAT10 inhibition with aPD-1.

Geometric quantum gates—engineered evolution paths for qubit control—promise noise resilience but have shown limited fidelity in prior implementations in semiconductor quantum computation. Here the authors demonstrate high-fidelity single-qubit gates in a single-hole quantum dot in Ge, outperforming conventional dynamical gates.

Multielectron molecular CO₂ reduction in acid is challenged by weak CO binding and competing hydrogen evolution. Here a methanol Faradaic efficiency of 62% is achieved in acid by tuning the microenvironment with cationic, hydrophobic and aerophilic layers.

Universal control of the state of qubits on timescales much shorter than the coherence time is necessary for quantum computation. The authors demonstrate electrical control of a charge qubit in quantum dots on the picosecond scale, which is orders of magnitude faster than previously reported.

The authors introduce and demonstrate a programmable optically-driven organic micro-actuator for precise manipulation of on-chip structures. This paves the way for adaptive, multifunctional photonic systems.

Copy number variants (CNV) are shown to contribute to the etiology of various genetic disorders. Here, authors present ECOLE, a deep learning-based somatic and germline CNV caller for WES data. Utilising a variant of the transformer architecture, the model is trained to call CNVs per exon.

Photonic synthetic dimension (on TFLN chip) attracts broad interest. Here, authors achieve tunable couplings via MZI-linked resonators, and prove its versatility by realizing multiple models including tight-binding lattice, the Hall ladder and Creutz ladder along with their featured phenomena

This study reveals the triboluminescence (TL) phenomenon of the metal halide perovskite film for the first time, which is based on a new mechanism of friction-induced lattice stretching, significantly distinct from that of the conventional TL.

Non-neighbouring mechanical resonators can interact via indirect coupling. Here, the authors leverage a resonant phonon cavity in a graphene-based electromechanical system to demonstrate strong indirect coupling between separated mechanical resonators.

It is uncertain how much life expectancy of the Chinese population would improve under current and greater policy targets on lifestyle-based risk factors for chronic diseases and mortality behaviours. Here we report a simulation of how improvements in four risk factors, namely smoking, alcohol use, physical activity and diet, could affect mortality. We show that in the ideal scenario, that is, all people who currently smokers quit smoking, excessive alcohol userswas reduced to moderate intake, people under 65 increased moderate physical activity by one hour and those aged 65 and older increased by half an hour per day, and all participants ate 200 g more fresh fruits and 50 g more fish/seafood per day, life expectancy at age 30 would increase by 4.83 and 5.39 years for men and women, respectively. In a more moderate risk reduction scenario referred to as the practical scenario, where improvements in each lifestyle factor were approximately halved, the gains in life expectancy at age 30 could be half those of the ideal scenario. However, the validity of these estimates in practise may be influenced by population-wide adherence to lifestyle recommendations. Our findings suggest that the current policy targets set by the Healthy China Initiative could be adjusted dynamically, and a greater increase in life expectancy would be achieved.

Optically active defects in hBN are promising for quantum sensing and information applications, however, coherent control of a single defect has not been achieved so far. By using an efficient method to produce arrays of defects in hBN, Guo et al. isolate a new carbon-related defect and show its coherent control.

Microcombs are vulnerable to the environmental perturbations. Here, the authors propose a universal mechanism to fully control the microcombs. Based this reconfigurable microsoliton, a wavemeter with a precision of kHz is demonstrated.

Lu et al. characterize cis-regulatory element dynamics at different stages of colorectal cancer progression and identify a functional variant associated with increased colorectal cancer risk because of selective transcription factor binding.

Here, Zhang et al. succeed in creating a heavily distorted oxygen deficient film of lanthanum cobaltite. The new phase of LaCoO_2.5 has several unique properties, most notably, a Curie temperature of 284 K, significantly larger than the films from which it was derived.

Stimulated Brillouin scattering is a non-linear interaction that allows light to be stored as coherent acoustic waves. Here, the authors report on Brillouin scattering-induced transparency in an optical microresonator whose high quality allows for long-lifetime non-reciprocal light storage.

Experimental demonstrations of genuine high-dimensional multipartite quantum nonlocality have been lacking so far. Here, the authors fill this gap using entangled photons, surpassing qubit-based limits and paving the way for device-independent quantum information processing in more complex systems.

Generation of multipartite entanglement between quantum states is crucial for developing quantum computation systems, although it has proven harder to achieve for photons than ions. Here, an eight-photon entangled state based on four independent photon pairs is observed, beating the previous record of six.

Different types of correlations in quantum mechanical systems are crucial for quantum information processing. Xu and colleagues determine the sizes of classical correlations, entanglement and other types of quantum correlations in an optical setup.

Reconfigurable topological phononic circuits that are based on micrometre-scale unsuspended waveguides and operate at 1.5 GHz can be used to create a topological phononic Mach–Zehnder interferometer that rapidly switches topological phonon transmission paths.

Establishing multi-degree-of-freedom entangled memories is important for high-capacity quantum communications and computing. Here, authors experimentally demonstrate hyper- and hybrid entanglement between two atomic ensembles in multiple degrees of freedom including path and orbital angular momentum.

Quantum-information processing requires gates that can operate on multiple qubits. Here, the authors demonstrate a controlled-NOT gate operation on two coupled charge qubits comprising electrons confined in semiconductor double quantum dots.

Photonic quantum memories are necessary for quantum information networks and can be built using cold atomic gases. In this work, Ding et al. show the first storage and retrieval of single photons carrying orbital angular momentum using electromagnetically induced transparency in a cold rubidium ensemble.

Subwavelength focusing of electromagnetic fields often uses evanescent waves and nanostructures to aid confinement. Here, the authors localize a microwave field to 6 orders of magnitude smaller than the wavelength, by coupling to confined electron oscillations in a hybrid nanowire-bowtie antenna.

Quantum memories are key components for quantum communication, but current storage times are still too short. Here, the authors use the atomic frequency comb protocol in a zero-first-order-Zeeman field to coherently store an optical pulse for an hour in a cryogenically cooled rare-earth doped crystal.

Van der Waals NbOCl2 crystal is a candidate platform for subwavelength thin film photon-pair sources. Here, the authors demonstrate generation of polarization entangled states from a two-layer stack of orthogonally oriented van der Waals crystal.

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

A round-robin differential phase shift protocol, in which monitoring of the signal disturbance is unnecessary, has been experimentally realized. With 65 pulses in each packet, the system can distribute a secret key over a distance of 90 km.

Upconversion nanoparticles, which convert lower-energy light into higher-energy light, have many potential applications including sensing and imaging. Here, Wen et al. review recent advances that have addressed concentration quenching and enabled increasingly bright nanoparticles, opening up their full potential.

Guo et al. evaluate three cutting-edge cell foundation models on a diverse kidney nuclei dataset and develop a training strategy leveraging multiple cell foundation models to reduce pathologist labeling costs. Findings reveal that current histopathology models need organ-targeted improvements, and the framework consistently boosts performance.

Iron and phosphorus exist at low concentrations in surface waters and may be co-limiting resources for phytoplankton growth. Here, the authors show that phosphorus deficiency increases the growth of iron-limited cyanobacteria through a PhoB-mediated regulatory network.

A quantum memory based on a Raman scheme is implemented for photonic qubits encoded in the path and polarization of single photons. The performance is quantified before and after storage in cold atomic ensembles and the storage bandwidth is ∼140 MHz.

Artificial intelligence-based detection of gastric cancer at different stages from noncontrast computed tomography is suggested to be feasible in a retrospective analysis of large and diverse cohorts, including real-world populations in opportunistic and targeted screening scenarios.

A van der Waals crystal, niobium oxide dichloride, with vanishing interlayer electronic coupling and considerable monolayer-like excitonic behaviour in the bulk, as well as strong and scalable second-order optical nonlinearity, is discovered, which enables a high-performance quantum light source.

A very uncommon detached binary system with a 20.5-min orbital period has been discovered to harbour a carbon–oxygen white dwarf star and a low-mass subdwarf B star with a seven-Earth radius that traces the theoretical limit of binary evolution predicted 20 years ago.

Synthetically replicating transmembrane protein signal transduction is a gaol of synthetic biology. Here, the authors show how the dimerization of synthetic transmembrane DNA receptors can be used to engineer sensing and actuation cascades in response to external molecular signals.

Minimizing the non-radiative energy loss without sacrificing the charge collection efficiency is the key to improve the performance of organic solar cells. Here, the authors develop hybrid side chain-based asymmetric small molecule acceptors and achieve maximum power conversion efficiency of 19.76%.