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Radiative cooling is an emerging technology for cooling with reduced energy consumption. Here the authors present photoluminescent composites that combine subambient cooling with aesthetic colour, hydrophobicity and durability.

Electrochemical hydrogenation of quinoxaline is a promising alternative to traditional methods but is limited by low current density and Faradaic efficiency. Here, the authors report a Ru single atoms doped Co₃O₄ nanosheet catalyst that regulates interfacial water to achieve excellent performance.

This study establishes MPXV clade IIb-infected SCID mouse models presenting with pneumonia, lesions, and localized inflammation that recapitulate key clinical manifestations observed in high-risk populations, and demonstrates that the timing of treatment initiation and the stage of disease progression critically influence the anti-MPXV efficacy of both tecovirimat and cidofovir.

To achieve simultaneous transparency and vivid multicolor switching in electrochromics is desirable owing to their potential as next-generation transparent displays. Here, the authors show a single-molecule design strategy that integrates a rhodamine moiety with a propylenedioxythiophene unit and incorporates molecular doping to achieve high optical transmittance with three distinct optical states.

Cation effects in electrocatalytic reactions have attracted considerable interest due to their role in modulating reaction kinetics and mechanisms. Here, the authors use constant-potential density functional theory and ab initio molecular dynamics simulations to study the atomic-scale synergy between Na⁺ ions and stepped Pt(311) surfaces in the alkaline hydrogen evolution reaction, reporting the formation of a Pt–H₂O–Na⁺(H₂O)ₓ adduct at the step edges that positions cations closer to the surface compared to Pt(111) terraces, resulting in a lower Volmer step activation energy.

The inherent scaling relationships among the adsorption energies of intermediates limit the efficiency of oxygen electrocatalysis. Here, a dual-atom catalyst with aligned orbital energy level is developed, driving the dissociative pathway to bypass scaling relationships towards enhanced performance.

Poly(vinylidene fluoride-co-trifluoroethylene)’s (PVDF-TrFE) piezoelectricity can be enhanced by annealing, however current annealing methods are slow. Here, the authors perform ultra-fast flash annealing of PVDF-TrFE to achieve a high piezoelectricity.

This study identifies monoclonal antibodies A138 and B026 targeting MPXV proteins M1R and B6R. Both antibodies exhibit neutralization of MPXV and VACV, and their combination enhances protective efficacy in mice, supporting a dual-targeting strategy.

This work demonstrates superadiabatic topological pumping on photonic chips, achieving a 20-fold device miniaturization and high-efficiency operation across a 650–920 nm bandwidth, paving the way for ultracompact integrated photonic transports.

Strong nonlinear optical response of most thin layered materials is often narrowband, especially in the mid-infrared spectral range. Here, authors experimentally observe second harmonic generation in the range of 1.2-5.0 μm from Weyl semiconductor tellurium nanoflakes. The generation efficiency is shown to be two orders of magnitude larger than that of GaSe.

Liu et al. present TemporalVAE, a method for integrating single-cell time course data. The model proposes a workflow to determine the biological timing of samples and its temporally sensitive genes, enabling single-cell developmental stage inference.

Mechanochemical probes allow for direct visualization of the stress and damage behaviors of polymeric materials but both processes cannot be simultaneously mapped with a single mechanophore. Here, the authors employed rhodamine-based mechanophores embedded in multiple network elastomers to visualize stress and damage under both homogeneous and inhomogeneous deformations.

Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: A six-year crossover study in a cold region.

This study designs covalent organic frameworks with robust dipole moments, enabling efficient hydrogen and hydrogen peroxide production from pure water using mechanical vibration and light.

Seawater electrolysis for green hydrogen is hindered by corrosive chloride ions. Here, the authors report a substrate-adaptive sacrificial corrosion strategy for creating highly active anodes that resist seawater corrosion and break thermodynamic selectivity limits.

Replicating the properties of spider silk in synthetic materials is desirable but challenging. Here, the authors report a wet-spinning method using anti-solvent phase separation for polymer hydrogel fibres with favourable structures and properties.

Conventional iridium catalysts suffer from instability due to surface amorphization into hydrous IrOx phase during reaction. Here, the authors report how a TiOx@Ti support transforms iridium nanoparticles into stable crystalline IrO2, enabling both high activity and durability in water electrolyzers.

The oxygen reduction reaction (ORR) is limited by the scaling relationship in the conventional oxygen associative pathway. In this study, single p-block atoms and interstitial H are incorporated into Pd metallenes favoring the direct dissociation mechanism, leading to high alkaline ORR performance.

The authors perform a genome-wide association study of adolescent idiopathic scoliosis patients of Han Chinese descent, and identify 3 new loci for disease susceptibility.

Hepatitis B virus is an ancient human pathogen that dates back more than 10,000 years. Here, the authors investigate the evolutionary history of the virus in Eastern Eurasia by sequencing 34 genomes dating from approximately 400–5,000 years ago and comparing them with other contemporary sequences.

A comparison of alpha diversity (number of plant species) and dark diversity (species that are currently absent from a site despite being ecologically suitable) demonstrates the negative effects of regional-scale anthropogenic activity on plant diversity.

Pangolins are a potential reservoir for viruses with cross-species infection potential. Here, the authors characterize a HKU4-related coronavirus isolated from pangolin and demonstrate its ability to infect human cell lines as well as its potential to infect transgenic mice expressing the human receptor DPP4.

Monitoring the diversity of viruses infecting animals is important for assessing zoonotic risk. Here, the authors use metatranscriptomics to characterise the viromes of small mammals, pangolins, and zoo animals in China to identify potentially zoonotic viruses.

Adjuvant gefitinib improves outcomes in non-small cell lung cancer (NSCLC) patients compared to chemotherapy, but not in all cases. Here, the authors find genomic biomarkers of response to gefitinib in NSCLC patients from the ADJUVANT trial, and propose a score to stratify them by potential benefit from the treatment.

Proton exchange membrane water electrolyzers suffer from high catalyst loading and sluggish oxygen evolution. Here, the authors report that tunnel-type iridium oxide concentrates activity at tunnel mouths, enabling high performance at low catalyst loading.

Cobaltosic oxide hollow dodecahedra with abundant oxygen vacancy defects was synthesized and manifested extraordinary catalytic performance toward the oxygen evolution reaction.

Pressure treatment can modify the luminescence properties of materials. Here the authors use pressure to turn nonemissive organic zinc halide perovskites bright with full color tunability, which enables robust optical anti-counterfeiting applications.

Here, the authors find that high-pressure treatment in a diamond anvil cell turns initially non-emissive organic small molecules emissive after decompression, where their color can be tuned through the maximum applied pressure.

Dual-atom catalysts are promising for CO₂ reduction reactions; however, sluggish kinetics limit practical applications. Now, a Ni dual-atom catalyst has been synthesized, realizing efficient electrocatalytic CO₂ reduction with a CO partial current density of ~1 A cm² at >99% Faradaic efficiency.

This prespecified updated survival and exploratory subgroup efficacy analysis of the phase 3 DESTINY-Breast04 trial shows that trastuzumab deruxtecan treatment in patients with HER2-low metastatic breast cancer leads to continuous survival benefit irrespective of estrogen receptor or hormone receptor status.

The limited durability of metal-nitrogen-carbon electrocatalysts hinders their use in proton exchange membrane fuel cells for the oxygen reduction reaction. Here the authors transform active sites from FeN4 to stable monosymmetric FeN2 + N’2 via chemical vapor modification, resulting in enhanced improving the durability of the catalyst.

Intestinal crypt-resident Acinetobacter radioresistens secretes indole acetic acid which activates an Ahr-Wnt-β-catenin-EphB2 signalling axis to promote intestinal stem cell homeostasis and prevent tumour initiation and colorectal cancer.

The contribution of tumor-infiltrating B cells in anti-tumor immunity is not yet fully understood. Here the authors show in two mouse models that tumor-specific antigen presentation by B cells, rather than antibody secretion, is essential for tumor suppression.

The SsCm1 effector of the pathogenic fungus Sclerotinia sclerotiorum, despite the lack of canonical chorismate mutase activity, inhibits chloroplast immunity and alleviates photoinhibition in host cells via stabilizing chloroplast protein MORF2.

Traditional lithographic techniques could damage organic semiconductor crystals due to high-energy beams or solvents. Here, authors employ a chemical-free nanoimprint crystallography method for fabrication of independent complex 2D patterns that exhibit good lasing performance and reproducibility.

The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous outbreaks and that the genetic diversity of the virus has increased substantially, with the emergence of several novel lineages.

Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.