Nature Search

TMEM145 is a key stereociliary component in the link structures of outer hair cells and mediates the secretion of stereocilin and tubby

The authors identify TMEM145 as a critical protein in cochlear outer hair cells, responsible for linking their stereocilia. Mice lacking TMEM145 develop severe hearing loss at an early age, providing new insights into hearing loss mechanisms.

Jae Won Roh
Kyung Seok Oh
Heon Yung Gee
ResearchOpen Access01 Dec 2025
Nature Communications

Volume: 17, P: 1-17
Aberrant maintenance of developmental transcription factor PAX6 promotes neuronal cell death via JNK3 signaling

Ji-Young Kim
Mi-Jin An
Jung-Woong Kim
ResearchOpen Access29 Jan 2026
Cell Death & Disease

P: 1-14
Factors associated with shock-refractory prehospital cardiac arrest

Kyung Hun Yoo
Byuk Sung Ko
Hye Jee Joo
ResearchOpen Access18 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Real-world outcomes of ranibizumab biosimilars in various retinal diseases: a Korean multi-center experience—ROSE Korea Study

Jae Ryong Song
Un Chul Park
Judy Kim
ResearchOpen Access09 Jan 2026
Scientific Reports

Volume: 16, P: 1-14
Mycobacterium tuberculosis-specific T cells restrain anti-cancer drug-induced neutrophilic lung inflammation in tuberculosis

Anti-cancer drugs could independently promote TB progression. Here, the authors show using mouse models, that anti-cancer drug treatments could induce delayed Mtb-specific T cell responses, followed by G-CSF dependent neutrophil manifestation in the lungs, leading to TB exacerbation.

Kee Woong Kwon
Tae Gun Kang
Sang-Jun Ha
ResearchOpen Access06 Oct 2025
Nature Communications

Volume: 16, P: 1-20
Production of Transgenic Cloned Miniature Pigs with Membrane-bound Human Fas Ligand (FasL) by Somatic Cell Nuclear Transfer

Jae Goo Seol
Soo Hyun Kim
Jae Young Heo
ResearchOpen Access15 Jun 2010
Nature Precedings

P: 1
Demonstration of CMOS-compatible memristor-based electrochemical biosensor transducer with threshold-sensing functionality

The study presents a CMOS-compatible memristor-based bio-to-electrical transducer with built-in threshold-sensing functionality, demonstrated for electrochemical biosensor applications.

Young-Joon Kim
Youna Kwon
Jongwon Lee
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 16, P: 1-11
Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death

Young Do Yoo
Young Min Chung
Hyung Jung Kim
ResearchOpen Access01 Sept 2002
Experimental & Molecular Medicine

Volume: 34, P: 273-277
A SARS-CoV-2 M^pro mutation conferring ensitrelvir resistance paradoxically increases nirmatrelvir susceptibility

SARS-CoV-2 variants resistant to current antivirals pose a significant threat, especially to high-risk patients. The authors identify a deletion mutation in M^pro that confers resistance to ensitrelvir but increases susceptibility to nirmatrelvir, suggesting potential for sequential or alternative therapeutic strategies in prolonged antiviral treatments.

Seong Cheol Min
Jin-Ju Seo
Min-Suk Song
ResearchOpen Access22 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Plasma GFAP as a mediator and moderator of Aβ, tau, and neurodegeneration in Alzheimer’s disease

Jun Sung Kim
Dahyun Yi
Hyeong Gon Yu
ResearchOpen Access09 Jan 2026
npj Dementia

Volume: 2, P: 1-8
Mutation analysis of p31^comet gene, a negative regulator of Mad2, in human hepatocellular carcinoma

Mi-Yong Yun
Sang Bum Kim
Kee-Ho Lee
ResearchOpen Access01 Aug 2007
Experimental & Molecular Medicine

Volume: 39, P: 508-513
FOXL2 posttranslational modifications mediated by GSK3β determine the growth of granulosa cell tumours

The majority of ovarian granulosa tumours harbour the C134W mutation in FOXL2 but the mechanism of tumorigenesis is largely unknown. Here, Kim et al. show that mutant FOXL2 is hyperphosphorylated by GSK3β, which targets the protein for degradation, and find that GSK3β inhibition represses the growth of ovarian granulosa cells.

Jae-Hong Kim
Yong-Hak Kim
Jeehyeon Bae
Research03 Jan 2014
Nature Communications

Volume: 5, P: 1-13
High-power electrically pumped microcombs

Combining a low-coherence source with silicon nitride ring resonators featuring normal group velocity dispersion enables electrically pumped, high-power microcombs, providing on-chip power up to 158 mW and high-coherence comb lines with linewidths as narrow as 200 kHz.

Andres Gil-Molina
Yair Antman
Michal Lipson
Research07 Oct 2025
Nature Photonics

Volume: 19, P: 1270-1274
Evaluation of a Apo-1/Fas promoter polymorphism in Korean stroke patients

Jung-Chul Seo
Sang-Won Han
Joo-Ho Chung
ResearchOpen Access01 Sept 2002
Experimental & Molecular Medicine

Volume: 34, P: 294-298
The efficacy of half saline in tumescent liposuction

Kyungho Paik
Nam Chul Kim
Chang-Hun Huh
ResearchOpen Access22 Dec 2025
Scientific Reports

Volume: 15, P: 1-7
A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy

Here, the authors show that higher levels of the gut bacterial clade TANB77 associate with better response to cancer immunotherapy, and further demonstrate in mice that a conserved pilin from TANB77 plays a role in enhancing immunotherapy efficacy, suggesting a potential therapeutic avenue.

Chan Yeong Kim
Dong Jin Park
Insuk Lee
ResearchOpen Access27 Dec 2024
Nature Communications

Volume: 15, P: 1-19
Impaired insulin secretion via the Wnt5a/β-catenin pathway contributes to diabetes development in pancreatic cancer

Minyoung Lee
Ho Seon Park
Shinae Kang
ResearchOpen Access28 Jan 2026
Experimental & Molecular Medicine

P: 1-12
Effect of petroleum ether extract of Panax ginseng roots on proliferation and cell cycle progression of human renal cell carcinoma cells

Jeongwon Sohn
Chul-Hee Lee
Woo Ik Hwang
ResearchOpen Access01 Mar 1998
Experimental & Molecular Medicine

Volume: 30, P: 47-51
Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin

Eui-Cheol Shin
Young Rim Seong
Jeon Han Park
ResearchOpen Access01 May 2002
Experimental & Molecular Medicine

Volume: 34, P: 114-122
Optically tunable catalytic cancer therapy using enzyme-like chiral plasmonic nanoparticles

Despite the potential of nanoparticles in facilitating cascade reactions in living organisms, precisely tuning each reaction within complex networks to enhance the catalytic activity is challenging. Here, the authors report a strategy to optically control each stage of cascade enzymatic reaction using chiral plasmonic nanoparticles under right- and left-handed circularly polarized light.

Haeun Kang
Subin Yu
Dong Ha Kim
ResearchOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-14
Photoautotrophic hydrogen production by eukaryotic microalgae under aerobic conditions

Eukaryotic algae and cyanobacteria can produce hydrogen in the presence of little or no oxygen. Here, the authors show that two microalgal strains are capable of producing hydrogen under aerobic conditions, and provide new insights into the natural evolution of oxygen-tolerant hydrogenase.

Jae-Hoon Hwang
Hyun-Chul Kim
Byong-Hun Jeon
Research04 Feb 2014
Nature Communications

Volume: 5, P: 1-6
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

Min-Seon Kim
Youngmi K Pak
Ki-Up Lee
Research18 Jun 2006
Nature Neuroscience

Volume: 9, P: 901-906
Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death

Seung-Chul Choi
Suk Ran Yoon
Hee Gu Lee
ResearchOpen Access01 Dec 2007
Experimental & Molecular Medicine

Volume: 39, P: 705-714
Exercise type and muscle fiber specific induction of caveolin-1 expression for insulin sensitivity of skeletal muscle

Yoon Sin Oh
Hyo Jeong Kim
Sang Chul Park
ResearchOpen Access01 Jun 2007
Experimental & Molecular Medicine

Volume: 39, P: 395-401
Roles of TNF-α and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride

Ok Hee Chai
Hern-Ku Lee
Chang Ho Song
ResearchOpen Access01 Oct 2005
Experimental & Molecular Medicine

Volume: 37, P: 408-417
Mucosal TLR5 activation controls healthspan and longevity

Understanding how the immune system’s functionality declines with age is crucial for addressing aging-related health issues. Here, the authors demonstrate that activating TLR5 in the mucosal layer can significantly improve healthspan and longevity, suggesting a novel approach for aging interventions.

Jae Sung Lim
Eun Jae Jeon
Kyung A Cho
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-14
The synthetic peptide, His-Phe-Tyr-Leu-Pro-Met, is a chemoattractant for Jukat T cells

Youndong Kim
Yoe-Sik Bae
Sung Ho Ryu
ResearchOpen Access01 Dec 2001
Experimental & Molecular Medicine

Volume: 33, P: 257-262
Mechanical and esthetic properties of denture base resins in relation to thermocycling

Ha Eun Choi
Sumin Kim
Kyung Chul Oh
ResearchOpen Access19 Nov 2025
Scientific Reports

Volume: 15, P: 1-8
Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway

Dong-Jo Kim
Jun-Ho Chung
Sang Chul Park
ResearchOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 401-407
Multi-point sensing organic light-emitting diode display based mobile cardiovascular monitor

Cardiovascular diseases require precise and continuous monitoring, but current PPG technology is limited to single-point sensing. Here, the authors present a display with organic photodiodes that enables multi-point PPG, high-resolution imaging, and user-interactive sensing.

Chul Kim
Kwangjin Lee
Changhee Lee
ResearchOpen Access15 Feb 2025
Nature Communications

Volume: 16, P: 1-15
An antioxidant modulates expression of receptor activator of NF-κB in asthma

Kyung Sun Lee
Hee Sun Park
Yong Chul Lee
ResearchOpen Access01 Jun 2006
Experimental & Molecular Medicine

Volume: 38, P: 217-229
Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome

Excessive NLRP3 inflammasome activation underlies inflammatory diseases such as gout. Here the authors show that orphan nuclear receptor small heterodimer partner protein (SHP) negatively regulates NLRP3, and its loss leads to accumulation of damaged mitochondria and gout-like immunopathology.

Chul-Su Yang
Jwa-Jin Kim
Eun-Kyeong Jo
ResearchOpen Access06 Feb 2015
Nature Communications

Volume: 6, P: 1-11
Fusogenic lipid nanoparticles for rapid delivery of large therapeutic molecules to exosomes

Exosomes have huge potential for drug delivery, but drug loading can be difficult. Here, the authors report on fusogenic lipid nanoparticles which, when mixed with exosomes rapidly fuse, non-destructively loading large drugs without compromising exosome biological functions, and demonstrate neurological application.

Gamsong Son
Jiyoung Song
Hojun Kim
ResearchOpen Access23 May 2025
Nature Communications

Volume: 16, P: 1-15
Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development

The regulation of KRAS oncoprotein stability remains to be completely determined. Here the authors identify that USP9X-mediated deubiquitination of KRAS protein is dependent on scaffolding protein NDRG3, suggesting KRAS-NDRG3 interaction as a targetable vulnerability in KRAS-driven cancers.

Han Koo
Kyung Chan Park
Dong Chul Lee
ResearchOpen Access16 Jan 2025
Nature Communications

Volume: 16, P: 1-17
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Chromatin accessibility of circulating CD8⁺ T cells differentiates disease severity in IgA nephropathy

Gwanghun Kim
Soojin Lee
Hyunah Ku
ResearchOpen Access30 Dec 2025
Scientific Reports

Volume: 16, P: 1-14
Relativistic frequency upshift to the extreme ultraviolet regime using self-induced oscillatory flying mirrors

Generation of ultrafast X-rays using lab-based laser sources is promising for numerous spectroscopic and imaging techniques. By generating a long underdense plasma in a solid, Kim et al.show relativistic frequency upshift of a laser pulse to 4.9 nm, caused by reflection from electron nanosheets.

I Jong Kim
Ki Hong Pae
Jongmin Lee
ResearchOpen Access27 Nov 2012
Nature Communications

Volume: 3, P: 1-7
Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1

Kyung Sun Lee
Ka Young Lee
Yong Chul Lee
ResearchOpen Access01 Dec 2007
Experimental & Molecular Medicine

Volume: 39, P: 733-745
Alternatively spliced mini-exon B in PTPδ regulates excitatory synapses through cell-type-specific trans-synaptic PTPδ-IL1RAP interaction

Synaptic adhesion molecules like PTPδ are critical for synapse formation and function. Here authors show PTPδ with mini-exon B regulates excitatory synapses in cell-type-specific and IL1RAP-dependent manners.

Seoyeong Kim
Jae Jin Shin
Eunjoon Kim
ResearchOpen Access13 May 2025
Nature Communications

Volume: 16, P: 1-20
Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection

Gil-Saeng Jeong
Gi-Su Oh
Hun-Taeg Chung
ResearchOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 393-400
A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor

Comparison between structures of human, mouse and rat P2X7 receptors define ortholog-specific pharmacology and facilitated structure-based drug design of UB-MBX-46, an antagonist that selectively inhibits the human P2X7 receptor with sub-nanomolar potency.

Adam C. Oken
Andreea L. Turcu
Steven E. Mansoor
ResearchOpen Access15 Sept 2025
Nature Communications

Volume: 16, P: 1-16
When bubble meets sludge

Piezoelectric ultrasound transducers generate transient cavitation that removes persistent fouling from mesh filters within seconds. This strategy enables stable, ultrahigh-flux wastewater treatment while substantially reducing energy demands.

Jae Chul Park
Jang Hwan Kim
Bong Hoon Kim
News & Views03 Dec 2025
Nature Water

Volume: 3, P: 1350-1351
Cation-eutaxy-enabled III–V-derived van der Waals crystals as memristive semiconductors

New two-dimensional semiconductors may exhibit properties beyond inherent semiconducting attributes. Here the authors report protonated semiconducting III–V-derived van der Waals crystals with memristive properties.

Jihong Bae
Jongbum Won
Wooyoung Shim
Research28 Aug 2024
Nature Materials

Volume: 23, P: 1402-1410
The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation

Microbiome-secreted proteins act as key modulators of host-microbiome crosstalk. Here, the authors show that Amuc_1409 protein, secreted from Akkermansia muciniphila, plays a key role in intestinal homeostasis by regulating intestinal stem cells through interaction with E-cadherin, indicating its potential as a biomolecule for improving gut health.

Eun-Jung Kang
Jae-Hoon Kim
Chul-Ho Lee
ResearchOpen Access06 Apr 2024
Nature Communications

Volume: 15, P: 1-20
Wnt-PLC-IP₃-Connexin-Ca²⁺ axis maintains ependymal motile cilia in zebrafish spinal cord

Ependymal cells are supporting cells in the central nervous system. Here the authors elucidate a signalling axis in zebrafish spinal cord ependymal cells that is important for motile cilia assembly and maintenance, demonstrating that it depends on intercellular propagation of calcium ions via connexin 43.

Jun Zhang
Gopalakrishnan Chandrasekaran
Seok-Yong Choi
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-14
Wafer-scale alignment and integration of micro-light-emitting diodes using engineered van der Waals forces

By engineering the upper and lower surfaces of micro-light-emitting-diode chips to have different van der Waals forces, hundreds and thousands of chips can be accurately aligned on substrates and used to create active-matrix displays.

Junsik Hwang
Hyun-Joon Kim-Lee
Kyungwook Hwang
Research30 Jan 2023
Nature Electronics

Volume: 6, P: 216-224
HPV E6 antisense induces apoptosis in CaSki cells via suppression of E6 splicing

Cheong Weon Cho
Haryoung Poo
Do Young Yoon
ResearchOpen Access01 May 2002
Experimental & Molecular Medicine

Volume: 34, P: 159-166
Association of castration-dependent early induction of c-myc expression with a cell proliferation of the ventral prostate gland in rat

Kyu Lim
Chung Park
Byung-Doo Hwang
ResearchOpen Access01 Dec 2000
Experimental & Molecular Medicine

Volume: 32, P: 216-221
Phylogenetic relationships and genetic diversity of the Korean endemic Phedimus latiovalifolius (Crassulaceae) and its close relatives

Myong-Suk Cho
Yongsung Kim
Seung-Chul Kim
ResearchOpen Access15 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Development of ligand-dependent regulatory system and its application to gene therapy of insulin-dependent diabetes mellitus

Jong-Min Kim
Soo-Jin Kim
Kyung-Sup Kim
ResearchOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 385-392

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