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Single-cell analysis of human atherosclerosis revealed distinct endothelial cell subclusters associated with inflammation, angiogenesis, and endothelial-to-mesenchymal transition.

Bulk superconductivity has been observed up to 96 K in pressurized bilayer nickelate single crystals which were synthesized under ambient pressure.

This study discovers giant negative thermal expansion (volume contraction) in PrMnO₃ above 1000 K, linked to a unique 3D network of elongated chemical bonds, offering a new design strategy for high-temperature volume contraction materials.

The development of fast-charging and high-capacity negative electrodes is critical for advanced lithium-ion batteries. Here, authors use a vacancy engineering strategy to develop a layered Prussian blue analogue with competitive rate capability, delivering a specific capacity of 510 mAh g⁻¹ at a specific current of 8 A g⁻¹.

Although platinum (Pt) surface is generally considered stable during hydrogen electrocatalysis, this study shows the formation of surface hydrides on sub-2-nm Pt nanoparticles during prolonged hydrogen adsorption/desorption, enhancing their catalytic activity.

Chen at al. show that CHD1 loss in SPOP-mutated prostate tumors confers castration resistance by increasing SREBP2-mediated cholesterol synthesis and subsequent androgen supply, an effect counteracted by combined androgen and cholesterol inhibition.

The efficiency of a quantum computer depends on which basic operations it can implement. Now a scheme that can implement any two-qubit logic gate has been demonstrated on a superconducting architecture.

Small Cas enzymes are required for therapeutic use. Here the authors report an Interaction, Dynamics and Conservation (IDC) strategy for protein miniaturisation and use this to generate five compact variants of Cas13 based on a combination of IDC strategy and AlphaFold2.

LYTAC strategies often face challenges in solid tumor penetration and synthesis. Here, the authors introduce Pep-TACs, a modular TFRC-based covalent peptide degradation platform that effectively degrades membrane protein PD-L1. This approach significantly suppresses both anti-PD-1-responsive and -resistant tumor growth, particularly in brain tumors.

Li-rich oxides face challenges such as voltage decay and slow kinetics due to irreversible anionic reaction. Here, authors activated the Ni-t2g orbitals through generating superexchange interactions via Be doping. By triggering the reduction coupling mechanism, the reversibility and kinetics of the anionic reaction are effectively improved.

Tracking electrical and mechanical activity in in-vitro cardiac microtissues is challenging. Here, authors develop tissue-like electronics that can ‘grow’ with the cardiac microtissues and realize the simultaneous tracking of both signals.

Sodium co-intercalation in graphite negative electrodes delivers high-rate kinetics, and yet its implementation is plagued by notorious reaction potential. Here, the authors develop a flexible electrolyte design strategy based on synergistically competitive coordination that tailors the co-intercalation potential to 0.4 V in dilute ether systems, providing screening guidance for more potential regulation electrolytes.

Balancing the activity and stability of oxygen electrocatalysts is challenging but crucial for rechargeable zinc-air batteries. Here, the authors report a highly active Cu-N-C catalyst boosted by the main-group element for zinc-air battery with a long cycle stability over 5000 h.

Phonons are thought to transport elastically across most interfaces. Here, the authors show that a substantial portion of phonons transport inelastically, adding another heat conduction channel and enhancing thermal conductance across interfaces.

Cheng Yang and co-workers develop a “popcorn-making-mimic” strategy to fabricate a uniformly compounded graphene@NiFe2O4 composite film with strong electromagnetic interference shielding and absorption capability.

Promoting solid ion-diffusion is essential for fast-charging battery. Here, authors present near-barrier-free ion dynamics in an amorphous organic-hybrid vanadium oxide-based zinc ion battery and developed Ah-level fast-charging pouch cell.

The histone methyltransferase ASH1L has been linked to tumorigenesis, mainly in leukemia. Here, authors report that ASH1L cooperates with HIF-1α to induce a pro-metastatic transcriptome in prostate cancer cells, and promotes conversion of monocytes to lipid-associated tumor-associated macrophages in the bone metastatic niche.

State-of-the-art electrolytes limit the cycle life of halide-ion batteries. Here, the authors report a fluorinated low-polar gel polymer electrolyte capable of improving the stability of the electrolyte and electrode interphases to boost battery performance.

A heterogeneous nickel-catalysed deuteration reaction of benzylic C(sp³)–H bonds in alkylarenes and methylarenes using D₂O is developed. Such metal–H₂–D₂O systems could be extended to other catalytic reactions for the preparation of deuterium-labelled compounds in the future.

The authors report a difluoroester electrolyte to enhance anion intercalation lithium metal batteries (AILMBs), improving safety and cyclability. This enables cost-effective graphitic carbon cathodes, with high durability, stability, and performance.

Closed pores govern sodium-ion storage performance of hard carbon negative electrodes. Here, authors link pore mouth size evolution of the closed pores to the solvation structure and propose design principles for optimizing both closed pores and intrinsic defects.

The energy content increase is of paramount importance for the development of future Li-based batteries. Here, the authors propose a gel polymer electrolyte in combination with a positive electrode comprising of a Li-rich oxide active material and graphite to produce a high-energy Li metal cell.

Intensive efforts are under way to develop Li metal batteries with ether electrolytes, but their performance fails to meet practical requirements. Here the authors develop an ether-based electrolyte for Li metal batteries that substantially improves battery cyclability, especially at low temperatures.

An untethered phototactic soft machine composed of poly(N-isopropylacrylamide) hydrogel blended with graphene oxide and gold nanoparticles demonstrates underwater full-space artificial phototaxis and manoeuvres around obstacles in natural sunlight.

Aqueous Zn batteries offer safety, but the Zn anodes are vulnerable to dendrite failure and side reaction. Here the authors show a low-cost electrolyte that involves hydrate salt and organic solvent but proves inflammable. The Zn battery cell delivers excellent performance even at a low temperature of −30 °C.

High-voltage non-aqueous lithium metal batteries suffer from poor cycling stability due to the presence of impurities in the electrolyte solution. Here, the authors report lithium hexamethyldisilazide to scavenge HF and H₂O, prevent the Ni dissolution and suppress side reactions during cycling.

2D materials are promising substrates for surface-enhanced Raman scattering (SERS)-based molecular sensing, but their performance is usually inferior to their plasmonic counterparts. Here, the authors report the synthesis of 1D/2D WO_3-x/WSe₂ heterostructures, showing high molecular sensitivity associated to ultrafast charge transfer timescales of ~1 ps.

The formation of lithium dendrites remains a great challenge to lithium metal batteries. Here the authors show an anode design to laterally direct the dendrite growth inside the compartments, providing a feasible post-mortem solution to batteries with lithium dendrites already present.

Interface chemistry is essential for highly reversible lithium-metal batteries. Here the authors investigate amide-based electrolyte that lead to desirable interface species, resulting in dense Li-metal plating and top-down Li-metal stripping, responsible for the highly reversible cycling.

The authors developed a highly conductive and dielectric composite solid-state electrolyte by coupling BaTiO₃ and Li_0.33La_0.56TiO_3–x nanowires with a side-by-side heterojunction structure in a polyvinylidene difluoride matrix, which simultaneously promotes the dissociation of lithium salts to produce more movable Li ions and efficiently transports the generated movable Li ions.

Developing stable and efficient non-iridium-based acidic oxygen evolution reaction electrocatalysts is crucial but challenging. Here, we report that non-stoichiometric Ti oxides can safeguard the Ru sites through charge-redistribution, thereby enhancing the catalytic performance.

Sodium ion batteries are known to benefit from the use of ether electrolytes. Here the authors reveal the origin showing that the energy barrier of charge transfer at the electrolyte/electrode interface dominates the interfacial electrochemical characteristics and is favorably small.

Sodium–sulfur batteries operating at a high temperature between 300 and 350°C have been used commercially, but the safety issue hinders their wider adoption. Here the authors report a “cocktail optimized” electrolyte system that enables higher electrochemical performance and room-temperature operation.