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Showing 1–50 of 62 results

Advanced filters: Author: Guifang Wang Clear advanced filters

A telomere-to-telomere gapless genome assembly of the Tibetan wild ass (Equus kiang)

Bilige Wuyun
Jie Liu
Xihe Li
ResearchOpen Access06 Jan 2026
Scientific Data

P: 1-11
Machine learning identifies exosome related gene signatures for early prediction of non-small cell lung cancer

Lin Zeng
Guifang Zhao
Xia Hu
ResearchOpen Access24 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Radiomics models with baseline MRI and clinical data to predict target therapy response and high-risk mortality in metastatic GIST

Guifang Lin
Quanjian Zhu
Yongjian Zhou
ResearchOpen Access04 Nov 2025
Scientific Reports

Volume: 15, P: 1-11
Deep learning analysis of histopathological images predicts immunotherapy prognosis and reveals tumour microenvironment features in non-small cell lung cancer

Youyu Wang
Xueming Ju
Xiaohua Li
Research25 Oct 2024
British Journal of Cancer

Volume: 131, P: 1833-1845
DirectRM: integrated detection of landscape and crosstalk between multiple RNA modifications using direct RNA sequencing

Profiling RNA modifications is essential to understanding their functions. Here, authors present DirectRM, a nanopore sequencing analytical tool that simultaneously detects six RNA modifications, revealing that modifications cluster at the transcript level but exclude each other on individual RNA molecules.

Yuxin Zhang
Yuecheng Wu
Kunqi Chen
ResearchOpen Access27 Oct 2025
Nature Communications

Volume: 16, P: 1-15
Molecular Epidemiology of Japanese Encephalitis Virus in Mosquitoes during an Outbreak in China, 2013

Zexin Tao
Guifang Liu
Aiqiang Xu
ResearchOpen Access09 May 2014
Scientific Reports

Volume: 4, P: 1-7
Sintilimab with two cycles of chemotherapy for the treatment of advanced squamous non-small cell lung cancer: a phase 2 clinical trial

Combining standard 4-6 cycles of chemotherapy with immune checkpoints inhibitors has shown to improve survival in patients with non-small cell lung cancer (NSCLC), however increased toxicities have also been reported. Here the authors report the results of a phase 2 trial of sintilimab (anti-PD1) with two cycles of chemotherapy for treatment of previously untreated advanced squamous NSCLC.

Mina Zhang
Guowei Zhang
Huijuan Wang
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-10
Author Correction: Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis

Bochen Jiang
Zhenhui Zhong
Chentao Lin
Amendments and CorrectionsOpen Access19 Dec 2023
Nature Plants

Volume: 10, P: 192
Circular hole pose estimation of porous workpiece based on binocular vision system

Hongcui Wang
Zhe Li
Guifang Duan
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-19
RNA demethylation increases the yield and biomass of rice and potato plants in field trials

Rice and potato plants are more productive after epitranscriptome engineering.

Qiong Yu
Shun Liu
Guifang Jia
Research22 Jul 2021
Nature Biotechnology

Volume: 39, P: 1581-1588
FTO-mediated formation of N⁶-hydroxymethyladenosine and N⁶-formyladenosine in mammalian RNA

Internal modifications in mRNA and non-coding RNA are necessary for modulating various intracellular signalling pathways. In this study, the authors report novel modifications resulting from oxidative RNA demethylation, which regulate RNA–protein interactions affecting gene expression.

Ye Fu
Guifang Jia
Chuan He
Research30 Apr 2013
Nature Communications

Volume: 4, P: 1-8
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis

The metastatic tumour microenvironment in pancreatic ductal adenocarcinoma (PDAC) remains to be explored. Here, the authors perform single cell RNA sequencing analysis for synchronously resected PDAC primary tumours and matched liver metastases and find differences in cellular composition.

Shu Zhang
Wen Fang
Ying Lv
ResearchOpen Access23 Aug 2023
Nature Communications

Volume: 14, P: 1-19
Multifaceted membrane interactions of human Atg3 promote LC3-phosphatidylethanolamine conjugation during autophagy

Here, Ye et al use high-resolution NMR in conjunction with in vitro and in vivo assays to show the catalytically important C-terminal regions of human Atg3 are conformationally dynamic and directly interact with the membrane, in collaboration with its N-terminal membrane curvature-sensitive helix.

Yansheng Ye
Erin R. Tyndall
Fang Tian
ResearchOpen Access07 Sept 2023
Nature Communications

Volume: 14, P: 1-12
RBM8A confers oxaliplatin resistance in gastric cancer by maintaining EGFR mRNA stability

Yichun Ma
Ying Xiang
Guifang Xu
Research07 Dec 2025
Oncogene

Volume: 45, P: 339-351
C²-methyladenosine in tRNA promotes protein translation by facilitating the decoding of tandem m²A-tRNA-dependent codons

Duan et al. demonstrate that the m²A modification is ubiquitous in plants and tRNA m²A37 promotes a relaxed conformation of tRNA, enhancing translation efficiency by facilitating decoding of tandem m²A-tRNA-dependent codons.

Hong-Chao Duan
Chi Zhang
Guifang Jia
ResearchOpen Access03 Feb 2024
Nature Communications

Volume: 15, P: 1-17
Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis

Arabidopsis photoreceptor CRY2 controls chlorophyll homeostasis by blue light-induced liquid–liquid phase separation of the CRY2/SPA1/FIO1 complex, resulting in activation of the m⁶A writer FIO1, regulating mRNAs encoding chlorophyll homeostasis proteins.

Bochen Jiang
Zhenhui Zhong
Chentao Lin
ResearchOpen Access08 Dec 2023
Nature Plants

Volume: 9, P: 2042-2058
An artificial intelligence system for qualified mucosal observation time during colonoscopic withdrawal

Wu-Jun Li
Peng Yan
Lei Wang
ResearchOpen Access18 Nov 2025
npj Digital Medicine

Volume: 8, P: 1-11
Root-inspired, template-confined additive printing for fabricating high-robust conformal electronics

Guifang Liu
Xiangming Li
Jinyou Shao
ResearchOpen Access14 Dec 2024
Microsystems & Nanoengineering

Volume: 10, P: 1-16
Rayleigh scattering in few-mode optical fibers

Zhen Wang
Hao Wu
Guifang Li
ResearchOpen Access24 Oct 2016
Scientific Reports

Volume: 6, P: 1-8
Targeting GPX2 to disrupt lipid homeostasis and enhance cisplatin sensitivity in diffuse gastric cancer

Yanmei Zhu
Yichun Ma
Guifang Xu
ResearchOpen Access27 Oct 2025
Cell Death Discovery

Volume: 11, P: 1-14
Cellular crosstalk mediated by Meteorin-like regulating hepatic stellate cell activation during hepatic fibrosis

Yuxia Zhou
Guifang Wang
Bing Guo
ResearchOpen Access20 May 2025
Cell Death & Disease

Volume: 16, P: 1-16
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics

Liu et al. show that the non-oxidative pentose phosphate pathway is crucial for maintaining regulatory T cell (T_reg) function, as deletion of transketolase in T_reg cells results in loss of immune tolerance in mice.

Qi Liu
Fangming Zhu
Xuemei Tong
Research23 May 2022
Nature Metabolism

Volume: 4, P: 559-574
Dual-resolving of positional and geometric isomers of C=C bonds via bifunctional photocycloaddition-photoisomerization reaction system

The simultaneous identification of position and configuration of double bonds in unsaturated lipids is challenging. Here, the authors develop a workflow for deep structural lipidomics to address this issue using a bifunctional reaction system combined with liquid chromatography-mass spectrometry, revealing double bond patterns in bacteria and in mouse brain ischemia.

Guifang Feng
Ming Gao
Suming Chen
ResearchOpen Access12 May 2022
Nature Communications

Volume: 13, P: 1-12
Antibody-free enzyme-assisted chemical approach for detection of N⁶-methyladenosine

An antibody-independent m⁶A profiling method called m⁶A-SEAL was developed via turning m⁶A into stable dm⁶A after treatment by FTO and DTT. This method exhibits better reliability in detection of transcriptome-wide m⁶A sites in humans and plants.

Ye Wang
Yu Xiao
Guifang Jia
Research27 Apr 2020
Nature Chemical Biology

Volume: 16, P: 896-903
Comparison of non-first-degree related donors and first-degree related donors in haploidentical HSCT: a multi-centre retrospective analysis

Yishan Ye
Mowang Wang
Yi Luo
Research24 May 2021
Bone Marrow Transplantation

Volume: 56, P: 2567-2574
LncRNA SNAI3-AS1 promotes PEG10-mediated proliferation and metastasis via decoying of miR-27a-3p and miR-34a-5p in hepatocellular carcinoma

Yarui Li
Dan Guo
Shuixiang He
ResearchOpen Access11 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-11
High performance organic-inorganic perovskite-optocoupler based on low-voltage and fast response perovskite compound photodetector

Dong Li
Guifang Dong
Liduo Wang
ResearchOpen Access20 Jan 2015
Scientific Reports

Volume: 5, P: 1-6
Cloning of the broadly effective wheat leaf rust resistance gene Lr42 transferred from Aegilops tauschii

The Aegilops tauschii-derived leaf rust resistance gene Lr42 has been widely used for breeding resistance wheat cultivars, but the molecular basis is unknown. Here, the authors show that Lr42 encodes an NLR-type of disease resistance gene by bulked segregant mapping in Ae. tauschii and confirm its function in common wheat.

Guifang Lin
Hui Chen
Sanzhen Liu
ResearchOpen Access01 Jun 2022
Nature Communications

Volume: 13, P: 1-12
Near complete assembly of Pyricularia penniseti infecting Cenchrus grass identified its eight core chromosomes

Yuyong Li
Xianjun Wang
Huakun Zheng
ResearchOpen Access31 Oct 2024
Scientific Data

Volume: 11, P: 1-7
M2-like tumor-associated macrophages transmit exosomal miR-27b-3p and maintain glioblastoma stem-like cell properties

Guifang Zhao
Lijuan Ding
Ling Qi
ResearchOpen Access04 Aug 2022
Cell Death Discovery

Volume: 8, P: 1-10
A model-free and distribution-free multi-omics integration approach for detecting novel lung adenocarcinoma genes

Shaofei Zhao
Caleb Qi
Guifang Fu
ResearchOpen Access03 Aug 2024
Scientific Reports

Volume: 14, P: 1-15
Siesta characteristics mediated the association between siesta duration and sleep quality in Chinese incoming college freshmen

Huiying Wang
Jiali Li
Lishun Xiao
ResearchOpen Access30 Dec 2024
Scientific Reports

Volume: 14, P: 1-11
Surface thermal oxidation on titanium implants to enhance osteogenic activity and in vivo osseointegration

Guifang Wang
Jinhua Li
Xinquan Jiang
ResearchOpen Access22 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
Effects of Sr-HT-Gahnite on osteogenesis and angiogenesis by adipose derived stem cells for critical-sized calvarial defect repair

Guifang Wang
Seyed-Iman Roohani-Esfahani
Xinquan Jiang
ResearchOpen Access20 Jan 2017
Scientific Reports

Volume: 7, P: 1-11
Comparison of leaf anatomical structure and photosynthetic characteristics between weedy rice and cultivated rice at the seedling stage

Lei Dai
Xiuren Zhou
Guifang Xu
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-11
Mutations in the glucocerebrosidase gene are responsible for Chinese patients with Parkinson’s disease

Zhe Yu
Ting Wang
Fabin Han
Research18 Dec 2014
Journal of Human Genetics

Volume: 60, P: 85-90
Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo

Guifang Du
Jing Wang
Yinying Lu
ResearchOpen Access12 Feb 2020
Cell Death & Disease

Volume: 11, P: 1-12
Evaluate the photosynthesis and chlorophyll fluorescence of Epimedium brevicornu Maxim

Jian Zaiyou
Tang Xiaomin
Xu Guifang
ResearchOpen Access14 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation

Ma et al. show that exposure of Caenorhabditis elegans to mitochondrial stress triggers stress adaptation in offspring, which is mediated by 6mA DNA modification at mitochondrial unfolded-protein-response genes.

Chengchuan Ma
Rong Niu
Ying Liu
Research03 Dec 2018
Nature Cell Biology

Volume: 21, P: 319-327
3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness

Guifang Gan
Zhaopeng Shi
Jun Mi
ResearchOpen Access06 Jul 2021
Cell Death Discovery

Volume: 7, P: 1-10
A METTL3–METTL14 complex mediates mammalian nuclear RNA N⁶-adenosine methylation

Certain adenosine residues within mammalian RNAs undergo reversible N6 methylation. Two methyltransferase enzymes, METTL3 and METTL14, as well as the splicing factor WTAP are identified as core components of the multiprotein complex that deposits RNA N⁶-methyladenosine (m⁶A) in nuclear RNAs.

Jianzhao Liu
Yanan Yue
Chuan He
Research06 Dec 2013
Nature Chemical Biology

Volume: 10, P: 93-95
The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation

Lifen Xu
Yuxia Zhou
Bing Guo
ResearchOpen Access27 Feb 2023
Cell Death & Disease

Volume: 14, P: 1-15
N⁶-methyladenosine-dependent regulation of messenger RNA stability

The mRNAs of higher eukaryotes are extensively modified internally with N⁶-methyladenosine, but the specific functional role of this modification has been unclear; here this modification on mRNA is shown to be recognized by several proteins, the modification and its recognition serve to regulate the RNA’s lifetime.

Xiao Wang
Zhike Lu
Chuan He
Research27 Nov 2013
Nature

Volume: 505, P: 117-120
Author Correction: Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells

Jinhua Qin
Mingyang Chang
Yunfang Wang
Amendments and CorrectionsOpen Access06 Apr 2020
Scientific Reports

Volume: 10, P: 1-2
Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure

Two membrane curvature-sensitive motifs in unstructured regions of the N-terminal domain of VPS37A are required for its phagophore recruitment and autophagosome closure.

Yansheng Ye
Xinwen Liang
Fang Tian
ResearchOpen Access15 Mar 2024
Communications Biology

Volume: 7, P: 1-12
Better pre-transplant treatment options for TP53-mutated MDS: cytoreductive or non-cytoreductive therapy?

Bingqian Jiang
Tingting Yang
Jimin Shi
Research04 Dec 2024
Bone Marrow Transplantation

Volume: 60, P: 326-334
Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling

Xinlei Sun
Li Yao
Ke Zen
Research28 Aug 2019
Mucosal Immunology

Volume: 12, P: 1280-1290
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells

Jinhua Qin
Mingyang Chang
Yunfang Wang
ResearchOpen Access22 Nov 2016
Scientific Reports

Volume: 6, P: 1-16
Effect of ebosin on modulating interleukin-1β-induced inflammatory responses in rat fibroblast-like synoviocytes

Yang Zhang
Lifei Wang
Yuan Li
Research04 May 2015
Cellular & Molecular Immunology

Volume: 13, P: 584-592
An omnidirectional visualization model of personalized gene regulatory networks

Chixiang Chen
Libo Jiang
Rongling Wu
ResearchOpen Access11 Oct 2019
npj Systems Biology and Applications

Volume: 5, P: 1-11

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