The growing aging population is increasing the burden of neurodegenerative diseases, which highlights the need to understand disease heterogeneity for better management. Using a transformer-based analysis of electronic health records, Lian et al. identified five distinct Alzheimer’s disease and Parkinson’s disease subtypes with unique clinical trajectories, comorbidities and genetic profiles, which enhances understanding of neurodegenerative disease heterogeneity.
- Thomas Nedelec
- Jean-Christophe Corvol