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Scientific Reports (105)
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Showing 1–50 of 175 results

Advanced filters: Author: Jin Hee Cha Clear advanced filters

Factors associated with shock-refractory prehospital cardiac arrest

Kyung Hun Yoo
Byuk Sung Ko
Hye Jee Joo
ResearchOpen Access18 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Fluorine-free binder-based dry thick electrodes with Parafilm^® M toward sustainable and efficient battery manufacturing

Fluorine-containing binders in battery dry electrode processing raise environmental concerns regarding restrictions on per- and polyfluoroalkyl substances. Here, authors show that a fluorine-free binder, Parafilm, can be an alternative to enable primer-free high-loading electrodes with stable cycling for sustainable lithium-ion batteries.

Min Kyung Kim
Taegyun Yu
Jinsoo Kim
ResearchOpen Access16 Dec 2025
Nature Communications

Volume: 16, P: 1-13
In vivo mitochondrial base editing restores genotype and visual function in a mouse model of LHON

Leber hereditary optic neuropathy (LHON) is caused by mtDNA mutations. Here, authors generated a mouse model with the common LHON mutation and showed that optimized TALE-like deaminases restored both phenotype and genotype via high-fidelity mitochondrial base editing.

Sanghun Kim
Jieun Kim
Hyunji Lee
ResearchOpen Access23 Nov 2025
Nature Communications

Volume: 16, P: 1-18
Diagnosis of thyroid nodules on ultrasonography by a deep convolutional neural network

Jieun Koh
Eunjung Lee
Jin Young Kwak
ResearchOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-9
Variations in survival outcomes of infants born at 22–23 weeks’ gestation by neonatal intensive care quality level in Korea

Ga Won Jeon
Minkyung Oh
Na Mi Lee
ResearchOpen Access05 Jan 2026
Scientific Reports

Volume: 16, P: 1-11
Artificial intelligence for breast cancer screening in mammography (AI-STREAM): preliminary analysis of a prospective multicenter cohort study

Artificial intelligence (AI) could improve mammography screening accuracy, but prospective evidence is still lacking. Here, the authors show in a prospective multicentre cohort study under single-read settings that the diagnostic accuracy of breast radiologists can significantly improve with AI-based computer-aided detection.

Yun-Woo Chang
Jung Kyu Ryu
Kyunghwa Han
ResearchOpen Access06 Mar 2025
Nature Communications

Volume: 16, P: 1-11
CHA₂DS₂-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation

Jeong-Eun Yi
Young Soo Lee
Junbeom Park
ResearchOpen Access21 Dec 2018
Scientific Reports

Volume: 8, P: 1-8
The difference of burden of ectopic beats in different types of atrial fibrillation and the effect of atrial fibrillation type on stroke risk in a prospective cohort of patients with atrial fibrillation (CODE-AF registry)

Seunghoon Cho
Jun Kim
Boyoung Joung
ResearchOpen Access14 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Structural insight into the distinct regulatory mechanism of the HEPN–MNT toxin-antitoxin system in Legionella pneumophila

HEPN–MNT is a bacterial type VII toxin-antitoxin (TA) system, comprising the HEPN toxin and the MNT antitoxin. Crystal structures and functional assays of the HEPN–MNT module suggest that HEPN is a metal-dependent RNase and identify its active site residues and regulatory mechanism.

Chenglong Jin
Cha-Hee Jeon
Bong-Jin Lee
ResearchOpen Access24 Nov 2024
Nature Communications

Volume: 15, P: 1-16
Histopathologic image–based deep learning classifier for predicting platinum-based treatment responses in high-grade serous ovarian cancer

Predicting the response to platinum-based chemotherapy in high-grade serous ovarian carcinoma (HGSOC) remains challenging. Here, the authors develop the histopathology image-based Pathologic Risk Classifier for HGSOC - PathoRiCH - to predict and stratify HGSOC patient response to therapy, especially when combined with molecular biomarkers.

Byungsoo Ahn
Damin Moon
Eunhyang Park
ResearchOpen Access18 May 2024
Nature Communications

Volume: 15, P: 1-13
Clinical impact of left atrial enlargement in Korean patients with atrial fibrillation

Min Soo Cho
Hyoung-Seob Park
Jun Kim
ResearchOpen Access10 Dec 2021
Scientific Reports

Volume: 11, P: 1-9
Clinical and Echocardiographic Risk Factors Predict Late Recurrence after Radiofrequency Catheter Ablation of Atrial Fibrillation

Yun Gi Kim
Jong-Il Choi
Young-Hoon Kim
ResearchOpen Access03 May 2019
Scientific Reports

Volume: 9, P: 1-9
Distinct spatiotemporal patterns of white matter hyperintensity progression

Researchers identified three distinct white matter hyperintensity progression patterns, validated in both patients and healthy individuals. Each pattern links to different vascular risks and outcomes, improving stroke prediction.

Jinyong Chung
Gilsoon Park
Dong-Eog Kim
ResearchOpen Access24 Oct 2025
Nature Communications

Volume: 16, P: 1-19
Versatile surface plasmon resonance of carbon-dot-supported silver nanoparticles in polymer optoelectronic devices

The coupling of surface plasmons and excitons in organic materials can improve the performance of organic optoelectronic devices. Carbon-dot-supported silver nanoparticles have now been used to improve the efficiency of polymer light-emitting diodes and polymer solar cells.

Hyosung Choi
Seo-Jin Ko
Jin Young Kim
Research21 Jul 2013
Nature Photonics

Volume: 7, P: 732-738
Therapy-induced senescent cancer cells contribute to cancer progression by promoting ribophorin 1-dependent PD-L1 upregulation

Conventional therapies can induce cancer cell senescence. Here the authors show that therapy-induced senescent cancer cells can escape T-cell immunity by upregulating PD-L1, whose expression and glycosylation levels are regulated by ribophorin 1.

Hyun Jung Hwang
Donghee Kang
Jae-Seon Lee
ResearchOpen Access03 Jan 2025
Nature Communications

Volume: 16, P: 1-20
Clinical impacts of concomitant left atrial appendage occlusion during mitral valve surgery in patients with mitral regurgitation

Jiwon Seo
Hee-Jung Lee
Chi Young Shim
ResearchOpen Access04 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Opioid use and subsequent delirium risk in patients with advanced cancer in palliative care: a multicenter registry study

Shin Hye Yoo
Jiseung Kang
Beodeul Kang
ResearchOpen Access12 Mar 2024
Scientific Reports

Volume: 14, P: 1-9
Correction: Corrigendum: Release of SOS2 kinase from sequestration with GIGANTEA determines salt tolerance in Arabidopsis

Woe-Yeon Kim
Zahir Ali
Dae-Jin Yun
Amendments and Corrections07 May 2013
Nature Communications

Volume: 4, P: 1
Disproportionality analysis of infection associated with antidiabetic drug use patterns

Tae Hyeon Kim
Kyeongmin Lee
Dong Keon Yon
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-11
Chloroquine and amodiaquine enhance AMPK phosphorylation and improve mitochondrial fragmentation in diabetic tubulopathy

Hye Yun Jeong
Jun Mo Kang
So-Young Lee
ResearchOpen Access08 Jun 2018
Scientific Reports

Volume: 8, P: 1-13
Effectiveness of 2D radiographs in detecting CBCT-based incidental findings in orthodontic patients

Jin-Young Choi
Song Hee Oh
Gerald Nelson
ResearchOpen Access29 Apr 2021
Scientific Reports

Volume: 11, P: 1-10
Multimodal AI model for preoperative prediction of axillary lymph node metastasis in breast cancer using whole slide images

Doohyun Park
Yong-Moon Lee
Dosik Hwang
ResearchOpen Access06 May 2025
npj Precision Oncology

Volume: 9, P: 1-13
Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest

Sejoong Ahn
Bo-Yeong Jin
Ji Hoon Kim
ResearchOpen Access18 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Plasma GFAP as a mediator and moderator of Aβ, tau, and neurodegeneration in Alzheimer’s disease

Jun Sung Kim
Dahyun Yi
Hyeong Gon Yu
ResearchOpen Access09 Jan 2026
npj Dementia

Volume: 2, P: 1-8
A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
ResearchOpen Access24 Jan 2023
Scientific Reports

Volume: 13, P: 1-8
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

Hyung-Lae Kim and colleagues report a genome-wide association study of quantitative traits of biomedical importance in Koreans. Although some loci were previously detected in European populations, others are new.

Yoon Shin Cho
Min Jin Go
Hyung-Lae Kim
Research26 Apr 2009
Nature Genetics

Volume: 41, P: 527-534
Exercise type and muscle fiber specific induction of caveolin-1 expression for insulin sensitivity of skeletal muscle

Yoon Sin Oh
Hyo Jeong Kim
Sang Chul Park
ResearchOpen Access01 Jun 2007
Experimental & Molecular Medicine

Volume: 39, P: 395-401
Author Correction: A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
Amendments and CorrectionsOpen Access14 Feb 2023
Scientific Reports

Volume: 13, P: 1
Automated interpretation of cardiotocography using deep learning in a nationwide multicenter study

Chang Eun Park
Byungjin Choi
Hye Jin Chang
ResearchOpen Access04 Jun 2025
Scientific Reports

Volume: 15, P: 1-10
Transient pacing in pigs with complete heart block via myocardial injection of mRNA coding for the T-box transcription factor 18

Intramyocardial injection of synthetic mRNA coding for the embryonic T-box transcription factor 18 gene generates rate-adaptive cardiac pacing and limits innate and inflammatory immune responses, as shown in rodents and pigs.

David W. Wolfson
Nam Kyun Kim
Hee Cheol Cho
ResearchOpen Access02 May 2024
Nature Biomedical Engineering

Volume: 8, P: 1124-1141
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

The amount of genetic material that can be packaged in AAV vectors used for genome editing is limited. Here the authors show that the smallest known Cas9 orthologue, cjCas9, can be packaged in a single AAV vector along with sgRNA and a marker gene, and demonstrate efficient gene editing in mice.

Eunji Kim
Taeyoung Koo
Jin-Soo Kim
ResearchOpen Access21 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Release of SOS2 kinase from sequestration with GIGANTEA determines salt tolerance in Arabidopsis

The flowering time and clock-related protein GIGANTEA has been broadly implicated in the development and physiology of plants. Kim and colleagues studyArabidopsisand find that GIGANTEA modulates salt stress via the release of the protein kinase SOS2, which is required for salt tolerance.

Woe-Yeon Kim
Zahir Ali
Dae-Jin Yun
Research15 Jan 2013
Nature Communications

Volume: 4, P: 1-13
Angiotensin II receptor blocker attenuates overexpression of vascular endothelial growth factor in diabetic podocytes

Eun-Young Lee
Myung Sook Shim
Choon Hee Chung
ResearchOpen Access01 Feb 2004
Experimental & Molecular Medicine

Volume: 36, P: 65-70
Shared genetic architectures of subjective well-being in East Asian and European ancestry populations

Won et al. compare genetic associations with subjective well-being in Korean and European populations, and show significant cross-population genetic correlations

Soyeon Kim
Kiwon Kim
Hong-Hee Won
Research19 May 2022
Nature Human Behaviour

Volume: 6, P: 1014-1026
Lipo-pam™ adjuvanted herpes zoster vaccine induces potent gE-specific cellular and humoral immune responses

Soo-Kyung Jeong
Su-Jin Ham
Eunyoung Chun
ResearchOpen Access17 Aug 2024
npj Vaccines

Volume: 9, P: 1-10
The Influence of the Variation in Sepsis Rate between Neonatal Intensive Care Units on Neonatal Outcomes in Very-Low-Birth-Weight Infants

Tae-Jung Sung
Jin A. Sohn
Jin A. Lee
ResearchOpen Access21 Apr 2020
Scientific Reports

Volume: 10, P: 1-11
β-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-κB activation

Se-Kyung Bai
Seon-Jin Lee
Young-Myeong Kim
ResearchOpen Access01 Aug 2005
Experimental & Molecular Medicine

Volume: 37, P: 323-334
SPP1+ macrophages in HR+ breast cancer are associated with tumor-infiltrating lymphocytes

Su Min Cha
Jung-Wook Park
Byung-Kwan Jeong
ResearchOpen Access30 Sept 2024
npj Breast Cancer

Volume: 10, P: 1-12
3D-cultured human placenta-derived mesenchymal stem cell spheroids enhance ovary function by inducing folliculogenesis

Tae-Hee Kim
Jong Ho Choi
Gi Jin Kim
ResearchOpen Access17 Oct 2018
Scientific Reports

Volume: 8, P: 1-11
Non-epitaxial single-crystal 2D material growth by geometric confinement

Geometric confinement on arbitrary substrates promotes, without epitaxial seeding, the layer-by-layer growth of two-dimensional single-crystal monolayers and bilayers of transition metal dichalcogenides.

Ki Seok Kim
Doyoon Lee
Jeehwan Kim
Research18 Jan 2023
Nature

Volume: 614, P: 88-94
Impact of pre-pregnancy body mass index and gestational weight gain on the risk of maternal and infant pregnancy complications in Korean women

Hansol Choi
Joong-Yeon Lim
Hyun-Young Park
ResearchOpen Access06 Sept 2021
International Journal of Obesity

Volume: 46, P: 59-67
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1

Lee et al. found that the ubiquitin-editing enzyme A20 promotes TGF-β1-induced EMT and metastases of breast cancer cells via ubiquitylation-mediated nuclear stabilization of Snail1.

Ji-Hyung Lee
Su Myung Jung
Seok Hee Park
Research11 Sept 2017
Nature Cell Biology

Volume: 19, P: 1260-1273
Long-term outcomes according to additional treatments after endoscopic resection for rectal small neuroendocrine tumors

Jae Hwang Cha
Da Hyun Jung
Hyun Jung Lee
ResearchOpen Access20 Mar 2019
Scientific Reports

Volume: 9, P: 1-8
The use of autologous platelet-rich plasma in embryo culture to obtain high-quality embryos

Yeo Jin Rhee
Jae Kyun Park
Woo Sik Lee
ResearchOpen Access18 Jul 2025
Scientific Reports

Volume: 15, P: 1-11
SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

SGLT2 inhibitors, a class of type 2 diabetes medication, reduce cardiovascular events in patients beyond expectation from blood sugar control. Here the authors report a randomized controlled trial showing that SGLT2 inhibitors reduce inflammasome activation in peripheral macrophages, which may contribute to the cardiovascular protection.

So Ra Kim
Sang-Guk Lee
Yong-ho Lee
ResearchOpen Access01 May 2020
Nature Communications

Volume: 11, P: 1-11
Diabetes Aggravates Post-ischaemic Renal Fibrosis through Persistent Activation of TGF-β₁ and Shh Signalling

Dong-Jin Kim
Jun Mo Kang
Sang-Ho Lee
ResearchOpen Access01 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
Father-inclusive chatbot-based prenatal education during COVID-19 pandemic enhances maternal–fetal attachment in Korean primigravida women across levels of partner support

Kyungmi chung
Kyungun Jhung
Jin Young Park
ResearchOpen Access05 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling

Transforming growth factor-β blocks the activation of pro-inflammatory cytokines, in part by the degradation of Myd88. This study shows that smad ubiquitin regulator proteins are shown to mediate the destruction of Myd8 and are therefore required for the anti-inflammatory effects of transforming growth factor-β.

Youn Sook Lee
Jin Seok Park
Seok Hee Park
Research06 Sept 2011
Nature Communications

Volume: 2, P: 1-11
Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

An analysis of gut microbiomes of patients with non-small-cell lung cancer reveals an association between Bifidobacterium bifidum abundance and response to cancer therapy. In murine models of syngeneic tumours, administration of commercial B. bifidum strains synergizes with immune checkpoint blockade to reduce tumour burden, but the therapeutic potential of B. bifidum is affected by strain-level variation.

Se-Hoon Lee
Sung-Yup Cho
Hansoo Park
Research11 Jan 2021
Nature Microbiology

Volume: 6, P: 277-288
Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancer

Sohyun Hwang
Ah-Young Kwon
Hee Jung An
ResearchOpen Access20 Jan 2020
Scientific Reports

Volume: 10, P: 1-10

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