Nature Search

Unveiling personalised targets of PD-1 blockade hyperprogression in a cervical adenocarcinoma via longitudinal single-cell and spatial monitoring

Zezhuo Su
Yue Xiao
Zhiyuan Xu
ResearchOpen Access13 Jan 2026
npj Precision Oncology

P: 1-13
The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

The role of protein UFMylation in cancer remains to be understood. Here, the authors show that UFM1-specific ligase 1 and AKT positively regulate each other through UFMylation and phosphorylation, facilitating lipid synthesis and breast tumor growth.

Fei Meng
Yating Du
Yan Chen
ResearchOpen Access20 Jan 2026
Nature Communications

Volume: 17, P: 1-18
A synergistic exploitation to produce high-voltage quasi-solid-state lithium metal batteries

The energy content increase is of paramount importance for the development of future Li-based batteries. Here, the authors propose a gel polymer electrolyte in combination with a positive electrode comprising of a Li-rich oxide active material and graphite to produce a high-energy Li metal cell.

Junru Wu
Xianshu Wang
Guoxiu Wang
ResearchOpen Access30 Sept 2021
Nature Communications

Volume: 12, P: 1-13
Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer

Gut microbial β-glucuronidases (gmGUSs) can potentially impact carcinogenesis in colorectal cancer (CRC). Here, the authors identify 550 gmGUSs in a public cohort of CRC patients as potential biomarkers for early diagnosis and therapeutic targets.

Junru Chen
Yan Li
Ru Yan
ResearchOpen Access27 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Suppression strategies for the polysulfide shuttle effect in electrolyte systems

Lithium-sulfur batteries are yet to achieve commercialization due to challenges associated with sulfur redox chemistry. This Review explores electrolyte design strategies, with a focus on preventing lithium polysulfide shuttling.

Junru Ke
Zhihua Wang
Si Lan
ReviewsOpen Access04 Nov 2025
Communications Materials

Volume: 6, P: 1-17
Kirkendall effect-induced uniform stress distribution stabilizes nickel-rich layered oxide cathodes

Nickel-rich layered oxide cathodes offer high energy density yet suffer from mechanical degradation during (de)lithiation. Here, the authors present a strategy that leverages the Kirkendall effect to equalize stress within the cathode particles, thereby stabilizing their structure and enhancing the cycling stability.

Ziyao Gao
Chenglong Zhao
Baohua Li
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-11
High-quality genome of a modern soybean cultivar and resequencing of 547 accessions provide insights into the role of structural variation

High-quality genome of the modern soybean cultivar Nongdadou2 and deep resequencing of 547 accessions provide insights into the role of structural variations in soybean improvement.

Caiying Zhang
Zhenqi Shao
Xihuan Li
Research09 Sept 2024
Nature Genetics

Volume: 56, P: 2247-2258
Melanin-like nanofibers with highly ordered structures achieve ultrahigh specific electromagnetic interference shielding efficiency

Lightweight electromagnetic shielding materials are of interest, though it is challenging to balance performance and processability with conventional materials. Here, the authors report, an ordered melanin-like polymer, using π–π stacking, for a microwave shielding material.

Peng Chen
Shibo He
Yiwen Li
ResearchOpen Access03 Aug 2025
Nature Communications

Volume: 16, P: 1-12
Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma

TFE3-translocation renal cell carcinoma (TFE3-tRCC) is a rare subtype of kidney cancer with no standard treatment options for the advanced disease. Here, the authors perform genomic and transcriptomic profiling of 63 untreated primary TFE3-tRCC tumours and reveal potential therapeutic targets.

Guangxi Sun
Junru Chen
Hao Zeng
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-13
Comprehensive molecular profiling of FH-deficient renal cell carcinoma identifies molecular subtypes and potential therapeutic targets

Currently, there is limited understanding of the molecular subtypes of fumarate hydratase (FH)-deficient renal cell carcinoma (RCC). Here, the authors employ integrated genomics and transcriptomics to develop a CpG site-specific methylation signature for the identification of FH-deficient RCC, and to identify three distinct molecular subtypes for this rare but highly lethal kidney cancer.

Xingming Zhang
Junjie Zhao
Guangxi Sun
ResearchOpen Access12 May 2025
Nature Communications

Volume: 16, P: 1-19
Photogating-assisted tunneling boosts the responsivity and speed of heterogeneous WSe₂/Ta₂NiSe₅ photodetectors

Photodetectors based on 2D materials can exhibit high photoresponsivity, but usually at the cost of their response speed. Here, the authors report a strategy based on photogating-assisted tunneling to overcome this trade-off in WSe₂/Ta₂NiSe₅ heterostructures.

Mingxiu Liu
Jingxuan Wei
Shaojuan Li
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-9
Pre-operative exercise therapy triggers anti-inflammatory trained immunity of Kupffer cells through metabolic reprogramming

Zhang et al. show that pre-operative exercise protects against liver injury by driving Kupffer cells towards an anti-inflammatory phenotype via itaconate metabolism.

Hongji Zhang
Tianmeng Chen
Hai Huang
Research14 Jun 2021
Nature Metabolism

Volume: 3, P: 843-858
Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion

Carnosine is a mobile buffering metabolite. Here the authors link carnosine accumulation, hypoxia and intracellular pH homeostasis in cancer cells as a mechanism of tumor immune evasion via NFX1 degradation and galectin-9 activity.

Ronghui Yan
Pinggen Zhang
Ping Gao
Research04 Jan 2024
Nature Immunology

Volume: 25, P: 483-495
Suppressing mosquito populations with precision guided sterile males

A. aegypti is the principal vector for arboviruses that impact on human health and wellbeing. Here the authors use precision guided sterile insect technique—pgSIT—to suppress or eliminate mosquito populations in multigeneration cage experiments.

Ming Li
Ting Yang
Omar S. Akbari
ResearchOpen Access10 Sept 2021
Nature Communications

Volume: 12, P: 1-10
Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment

Intermittent fasting (IF) has been shown beneficial in reducing metabolic diseases. Here, using a multi-omics approach in a T2D mouse model, the authors report that IF alters the composition of the gut microbiota and improves metabolic phenotypes that correlate with cognitive behavior.

Zhigang Liu
Xiaoshuang Dai
Xuebo Liu
ResearchOpen Access18 Feb 2020
Nature Communications

Volume: 11, P: 1-14
Predicting porosity in tight sandstone reservoirs based on logging while drilling engineering parameters

Dongyang Xue
Ligang Zhang
Chenxu Jiang
ResearchOpen Access24 Apr 2025
Scientific Reports

Volume: 15, P: 1-12
Quantum algorithm for MMNG-based DBSCAN

Xuming Xie
Longzhen Duan
Junru Li
ResearchOpen Access30 Jul 2021
Scientific Reports

Volume: 11, P: 1-8
Weight-adjusted waist index as a new predictor of osteoporosis in postmenopausal patients with T2DM

Guohui Du
Linna Zeng
Fuzai Yin
ResearchOpen Access25 Apr 2025
Scientific Reports

Volume: 15, P: 1-8
Tunable itinerant spin dynamics with polar molecules

Tunable itinerant spin dynamics enabled by dipolar interactions are demonstrated with polar molecules, establishing an interacting spin platform that allows for exploration of many-body spin dynamics and spin-motion physics using strong, tunable dipolar interaction.

Jun-Ru Li
Kyle Matsuda
Jun Ye
Research01 Feb 2023
Nature

Volume: 614, P: 70-74
Tuning of dipolar interactions and evaporative cooling in a three-dimensional molecular quantum gas

Realizing the potential of dipolar molecular gases to explore quantum physics needs elastic, tunable interactions and low temperatures. This is now possible due to advances in control that suppress molecular losses and enable efficient cooling.

Jun-Ru Li
William G. Tobias
Jun Ye
Research02 Sept 2021
Nature Physics

Volume: 17, P: 1144-1148
Physisorption-assistant optoelectronic synaptic transistors based on Ta₂NiSe₅/SnS₂ heterojunction from ultraviolet to near-infrared

Fan Tan
Chunlu Chang
Shaojuan Li
ResearchOpen Access17 Mar 2025
Light: Science & Applications

Volume: 14, P: 1-12
MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT

Chengbin Zhao
Ruiming Guo
Bo Yang
ResearchOpen Access11 Jun 2020
Scientific Reports

Volume: 10, P: 1-12
FLT1-enriched extracellular vesicles induce a positive feedback loop between nasopharyngeal carcinoma cells and endothelial cells to promote angiogenesis and tumour metastasis

Fei Li
Lin Song
Qing Zhang
Research13 Apr 2025
Oncogene

Volume: 44, P: 2253-2267
Comprehensive systems biology analysis reveals splicing factor contributions to cutaneous melanoma progression

Shuting Zhu
Rui Zhu
Wenna Guo
ResearchOpen Access19 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
A comprehensive psychological tendency prediction model for pregnant women based on questionnaires

Xiaosong Han
Mengchen Cao
Renchu Guan
ResearchOpen Access02 Jan 2023
Scientific Reports

Volume: 13, P: 1-13
Study on stress variation of advance fiberglass anchor bolts during tunnel excavation process

Jimeng Feng
Yumei Tan
Hongtao Li
ResearchOpen Access13 Mar 2023
Scientific Reports

Volume: 13, P: 1-15
Comprehensive Benchmark Dataset for Pathological Lymph Node Metastasis in Breast Cancer Sections

Xitong Ling
Yuanyuan Lei
Yonghong He
ResearchOpen Access07 Aug 2025
Scientific Data

Volume: 12, P: 1-15
IR-780 Dye as a Sonosensitizer for Sonodynamic Therapy of Breast Tumor

Yekuo Li
Qunfang Zhou
Hairong Zheng
ResearchOpen Access13 May 2016
Scientific Reports

Volume: 6, P: 1-10
Systematic correspondence in co-evolving languages

Junru Wu
Junyuan Zhao
ResearchOpen Access02 Aug 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-19
Transmissibility of hand, foot, and mouth disease in 97 counties of China

Wei Zhang
Jia Rui
Tianmu Chen
ResearchOpen Access08 Mar 2022
Scientific Reports

Volume: 12, P: 1-15
Modified stochastic medium prediction model for the deformation response of concealed underground stations under existing pipelines

Junru Zhang
Tong Pan
Chao Kong
ResearchOpen Access17 Jun 2023
Scientific Reports

Volume: 13, P: 1-15
A real-world pharmacovigilance study of FDA Adverse Event Reporting System (FAERS) events for osimertinib

Yanchao Yin
Yamin Shu
Juan Li
ResearchOpen Access15 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa

Yao Wang
Leiqiong Gao
Ziyu Hua
ResearchOpen Access06 Sept 2018
Scientific Reports

Volume: 8, P: 1-10
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase

Yinghui Wang
Hui Lu
Ping Gao
ResearchOpen Access02 Oct 2021
Cell Death & Disease

Volume: 12, P: 1-13
High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma

Beng Yang
Xiaode Feng
Shusen Zheng
ResearchOpen Access11 Sept 2020
Oncogene

Volume: 39, P: 6529-6543
New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine

Hanli Xu
Shuye Lin
Jiaqiang Huang
ReviewsOpen Access17 May 2023
Cellular & Molecular Immunology

Volume: 20, P: 739-776

Search

Unveiling personalised targets of PD-1 blockade hyperprogression in a cervical adenocarcinoma via longitudinal single-cell and spatial monitoring

The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

A synergistic exploitation to produce high-voltage quasi-solid-state lithium metal batteries

Gut microbial β-glucuronidases and their role in the microbiome-metabolite axis in colorectal cancer

Suppression strategies for the polysulfide shuttle effect in electrolyte systems

Kirkendall effect-induced uniform stress distribution stabilizes nickel-rich layered oxide cathodes

High-quality genome of a modern soybean cultivar and resequencing of 547 accessions provide insights into the role of structural variation

Melanin-like nanofibers with highly ordered structures achieve ultrahigh specific electromagnetic interference shielding efficiency

Integrated exome and RNA sequencing of TFE3-translocation renal cell carcinoma

Comprehensive molecular profiling of FH-deficient renal cell carcinoma identifies molecular subtypes and potential therapeutic targets

Photogating-assisted tunneling boosts the responsivity and speed of heterogeneous WSe₂/Ta₂NiSe₅ photodetectors

Pre-operative exercise therapy triggers anti-inflammatory trained immunity of Kupffer cells through metabolic reprogramming

Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion

Suppressing mosquito populations with precision guided sterile males

Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment

Predicting porosity in tight sandstone reservoirs based on logging while drilling engineering parameters

Quantum algorithm for MMNG-based DBSCAN

Weight-adjusted waist index as a new predictor of osteoporosis in postmenopausal patients with T2DM

Tunable itinerant spin dynamics with polar molecules

Tuning of dipolar interactions and evaporative cooling in a three-dimensional molecular quantum gas

Physisorption-assistant optoelectronic synaptic transistors based on Ta₂NiSe₅/SnS₂ heterojunction from ultraviolet to near-infrared

MicroRNA-128-3p Enhances the Chemosensitivity of Temozolomide in Glioblastoma by Targeting c-Met and EMT

FLT1-enriched extracellular vesicles induce a positive feedback loop between nasopharyngeal carcinoma cells and endothelial cells to promote angiogenesis and tumour metastasis

Comprehensive systems biology analysis reveals splicing factor contributions to cutaneous melanoma progression

A comprehensive psychological tendency prediction model for pregnant women based on questionnaires

Study on stress variation of advance fiberglass anchor bolts during tunnel excavation process

Comprehensive Benchmark Dataset for Pathological Lymph Node Metastasis in Breast Cancer Sections

IR-780 Dye as a Sonosensitizer for Sonodynamic Therapy of Breast Tumor

Systematic correspondence in co-evolving languages

Transmissibility of hand, foot, and mouth disease in 97 counties of China

Modified stochastic medium prediction model for the deformation response of concealed underground stations under existing pipelines

A real-world pharmacovigilance study of FDA Adverse Event Reporting System (FAERS) events for osimertinib

Characterization of lasR-deficient clinical isolates of Pseudomonas aeruginosa

Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase

High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma

New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine

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