Fatty acid-binding proteins (FABPs) are members of a highly conserved family of proteins central to lipid-mediated processes and related metabolic and immune response pathways. Here, the authors review the functions of individual FABP family members, emphasizing the potential of FABP inhibition as a novel strategy in the treatment of disorders of the metabolic syndrome including obesity, diabetes and atherosclerosis.
- Masato Furuhashi
- Gökhan S. Hotamisligil
